'Beavertail' Surgery Helps Tongue Cancer Patients
...e swallowing process; the base of a healthy tongue acts as a piston that pushes food down the throat. With surgery, the reconstructed tongue instead acts as a buttress, which squeezes the food into the esophagus. There are about 900 cases of cancer of ...A New Strategy to Control Breast Cancer
...CE (tumor necrosis factor-alpha-converting enzyme) acts like a “molecular scissors” that releases a pair of ligands, called Amphiregulin and TGF-alpha, from the cell surface. These ligands activate EGFR. EGFR, which stands for Epidermal Growth Factor Receptor, is the protein on the outer surface of a ce...WBC in Lung Produces Histamine: Study
... Caughey says the result could mean that histamine acts as a link between airway infections and asthma and bronchitis, which are associated with allergy. "In both, we observe inflammation –– swelling, blood vessel leak, and muscle contraction that narrows the airway." Caughey was investigating the well-......h at the Kottayam Medical College hospital through acts of ‘negligence’ and ‘corruption’. KGMCTA, Indian...h at the Kottayam Medical College hospital through acts of ‘negligence’ and ‘corruption’. KGMCTA, Indian Medical Association, P G Association and Medical Co...How Many Genes Does It Take to Learn? Lessons from Sea Slugs
...ion of the journal Cell. The findings suggest that acts of learning or the progression of brain disorders do not take place in isolation - large clusters of genes within an untold amount of cells contribute to major neural events. "For the first time we provide a genomic dissection of the memory-formin...Researchers Identify New Drug Targets for Cancer
...sing a tumor suppressor gene, which is a gene that acts to prevent cell growth. If a mutation occurs in this gene, it makes the individual – or in this case, the mouse – more susceptible to the development of cancer in the tissue in which the mutation occurs. “When we created mice missing a tumor suppr...Glucose Sensor That Controls Glucose Metabolism Identified
...ays an important role in metabolism of glucose. It acts like a switch that increases or decreases the manu...t of triglycerides into the bloodstream. Since LXR acts as the body's sensor of a buildup of pathogenic cholesterol, its ability to bind both glucose and ox...Mayo Researcher Discovers Target Site for Developing Mosquito Pesticides
...earchers elsewhere found that the cysteine residue acts as a hook that could tether a small molecule in the active site of an enzyme and permanently damage the enzyme. This led Dr. Pang to believe the cysteine and arginine residues could be targeted by a pesticide that would not affect humans and other ma...Researcher Discovers Target Site for Developing Mosquito Pesticides
...earchers elsewhere found that the cysteine residue acts as a hook that could tether a small molecule in the active site of an enzyme and permanently damage the enzyme. This led Dr. Pang to believe the cysteine and arginine residues could be targeted by a pesticide that would not affect humans and other ma...Impotent? No Problem – Have An Injectio
...rated into a packet of DNA called a plasmid, which acts as a carrier. The lead investigator Dr. Arnold Melman told Reuters Health, " The results of the early-stage trial suggest that the technology worked. We have shown that we could give a safe vector, naked DNA, and the hSlo gene and obtain an expecte...Brain Images Show Hysteria Not an Imaginary Disorder
...y this happens could be that bilateral stimulation acts as a distraction, shifting the patient’s attention, and thereby overcoming the inhibition. “Future studies plan to build on these findings by scanning more subjects and healthy controls,” said Ghaffar. “In addition, a study examining the role of di...Protein ‘Fingerprint’ in Spinal Fluid Could Spot Alzheimer’s Disese
...3 protein biomarkers// in cerebrospinal fluid that acts as a neurochemical “fingerprint,” which doctors might use someday to identify patients living with Alzheimer’s disease. The research will be published in the December online-edition of the journal Annals of Neurology. Right now, physicians rely o...Patients' Requests for Antidepressants can Influence Physician Evaluation of Depression
...ts would be screened for the existence of suicidal acts or impulses. The research was led by an investigator at the University of California, San Francisco (UCSF) in collaboration with researchers from the University of California, Davis and the University of Rochester. In a previous study, the first...From a Lowly Yeast, Researchers Divine a Clue to Human Disease
...ns when it doesn't work properly. Normally, Sen1 acts like a molecular stop sign, telling another protein called RNA polymerase II when to stop transcribing genetic information from DNA into related threads of RNA. The polymerase reads along DNA strands, building RNA as it goes. Multiple genes strung al...A New Rapid 3-D Cell-Growth Technique For Growing Heart Muscle
...n that included additional calcium and a drug that acts on beta-adrenergic receptors. Both are important to the signaling required to produce cohesive action by cells in tissue. The U-M team also assessed the BEHM's structure and function at different stages in its development. First author and postdoc...Underweight Moms: Weighed Down by the Risk of Miscarriages
...riage. This seems to imply that ‘morning sickness’ acts like an indicator that announces that all is well with the pregnancy. The findings of this research will definitely be an encouragement to women. Hopefully this will spur them on to include more veggies and fruits in their diet, commented lead res...Zinc – A New Key Player In Brain Circuitr
...mportant, since it directly demonstrates that zinc acts as an endogenous modulator of synaptic transmission." They wrote that the findings "will certainly revive the flagging hopes of zincologists. This work provides a clear demonstration that interfering with zinc modulation of a synaptic pathway leads t...Regulatory Mechanism for Tumor Suppressor Protein Identified
... half of human cancers. When working properly, p53 acts by binding to DNA to activate genes that direct cells with damaged DNA to cease dividing until the damage can be repaired. Cells with such damage include cancer cells, since all cancers track to genetic flaws of one kind or another, whether inherited......od. Composed of apple puree and oregano oil, which acts as a natural antibacterial agent, the coating shows promise in laboratory studies of becoming a long-lasting, potent alternative to conventional produce washes, according to a team of scientists from the U.S. Department of Agriculture (USDA) and the ...