New Surgical Technique Decreases Colorectal OR Time
...ed in its normal place." The GelPort device also acts to seal in gas that is introduced into the abdominal cavity to give the surgeon more room during the laparoscopic portion of the procedure. Dr. Richard L. Whelan, chief of colon and rectal surgery at NewYork-Presbyterian/Columbia University Medical...Rare Mutation Causes Early Heart Disease and Metabolic Syndrome
...und a single mutation in a gene called LRP6, which acts in the Wnt signaling pathway and which was previously known to be involved in development and in certain forms of cancer. The mutation changed one amino acid in the protein, which the team showed altered the activity of the protein encoded by LRP6. ...Access to Pornography Among Teenagers on the Rise
... DVD, but suggests that parents may think distance acts as a buffer. “Maybe they have a false sense of thinking they are far away from unhealthy influences.” Rural boys also reported a lower incidence of parents talking with them about sexual media content. Urban girls were most likely to have had discuss...No Scientific Evidence to Support Drug Safety Recommendations
...luence from the pharmaceutical industry that these acts may have invited have also played a role. Yet the scientific basis that too many unsafe drugs enter the market is lacking. The IOM report does not document, for example, whether the reductions in approval times for bringing drugs to the market nega...Primitive Yeast Yields Secrets Of Human Cholesterol And Drug Metabolism
... “Collectively, our experiments suggest that Dap1 acts as a common regulator of cytochrome P450s in mammals,” says Espenshade. Because Dap1 affects one particular P450 responsible for drug metabolism, Espenshade suspects that genetic variations in the genetic blueprint coding for Dap1 may provide clue...Never-Betrayed Men Less Likely to Indulge in Child Sex Abuse
...cused toward men to help them understand that such acts do occur and that the abuse often can contribue to a number of societal ills. Among the problems, she noted, are mental and physical health problems, substance abuse, victimization and criminality in adulthood. 'There is a very high prevalence of c...New Mechanism for Nutrient Uptake Discovered
...T1;1, located at the surface of the cell membrane, acts as a switch. "The terminus is an arm-like feature that physically grabs a neighboring short-chain molecule, binds with it, and changes the shape of itself and its neighbor thereby activating all the pores in the complex," continued Loqué. "The pore...Mental Health of Kashmiris Needs Urgent Attention: Survey
...on of impunity in Kashmir for those who perpetrate acts of terror and violence against the people of the region. Until this cycle of violence is addressed, the situation of the people of Kashmir cannot be improved, says MSF. Source-IANS SR......ne to breakage. They found the microscopic protein acts like a tiny Slinky spring toy within the coating of nerve cells, giving them strength. When 1-millimeter-long nematode worms were bred with the mutant gene, they lacked beta spectrin, resulting in breakage of their nerve cells' axons, the long, wir...How Bacteria Generate Energy to Live?
...trations between outside and inside. This gradient acts like a battery that powers essential cell functions, such as the movement of the bacterium’s tail, the flagellum. Most cells, including human cells, use gradients of protons for this energy conservation function, but enzymes that work with sodium i...Immune System Gears Up by Specific Enzymes
...dulating the expression of a molecule, LAG-3, that acts as an immunological molecular brake. In turn, this process is controlled by the strength of the T cell receptor signal—the immunological ‘accelerator.’ So the more the T cell ‘accelerates,’ the more the ‘brake’ is released.” The St. Jude team prev...Reactivated Genes Cause Tumors to Shrink (or) Disappear
...l drugs now under investigation, known as nutlins, acts by interfering with MDM2, an enzyme that keeps p53 levels low. In follow-up studies, the MIT researchers are looking at other types of cancer, such as epithelial (skin) cancer, in their mouse model, and they plan to see if the same approach will al...Single Protein Plays A Major Role In Prion Diseases
...disperse. Prion protein works the same way. Hsp104 acts like the wind, blowing apart the flower and spreading the seeds."Serio said that prions still multiply without fragmentation. However, she said, they do so at a much slower rate. So a drug that blocked the activity of Hsp104 could seriously slow prog...Scientists Identify Gene That May Indicate Predisposition To Schizophrenia
...nd family-based investigations. The CHI3L1 gene acts as a survival factor in response to adverse environments, countering various types of physiological stress, such as inflammation, nutrient deprivation, and oxygen deficiency, all of which may induce high expression of CHI3L1. The gene is located on c...Cancer Scientists' Gene Research Offers New Treatment Hope
...In fact, the first anti-cancer drug, Methotrexate, acts by binding and inhibiting the enzyme produced by this gene," he said. The Oxford study is to be published in the journal Nature. Another approach is being adopted by Professor Michael Weller, medical director of general neurology at the University ...First Liver Donation in Armed Forces
...eral Medical Services (Army), said: 'Such selfless acts are typical of armed forces personnel and would serve as an inspiration to others.' Source-IANS...Role of RNA in Checking the Development of Tumors
...In fact, the first anti-cancer drug, Methotrexate, acts by binding and inhibiting the enzyme produced by this gene." Dr Akoulitchev believes that understanding how we can use the RNA to switch off or inhibit DHFR and other genes may have important therapeutic implications for developing new anti-cancer t...Lead With a Poisonous Electron Shield
...emerging free electron pair of the lead cation. It acts as an electronic shield on one side, pushing away the fourth ligand. Such a dramatic geometrical distortion at the active center could explain why lead inhibits this enzyme. The different behavior of lead in these two enzymes demonstrates that it c......ir, imparting a brown or black color. This pigment acts as a natural sunscreen and renders protection while being exposed to the sun. The fair-skinned folks lack this protection and melanoma results. Besides, the dark-skinned people are blessed with more youthful suppleness, resulting in the product......me and the status conferred on a scientist somehow acts like a health booster and prolonged his life. This research was titled "Mortality and Immortality" and published this month. PRI...