Researchers Identify Immune Dysfunction in Melanoma Patients
...ly to a molecule called interferon, which normally activates the immune system. Without the ability to respond to interferon, the cells are less able to fend off the cancer, according to the study that will be published in the May issue of Public Library of Science-Medicine. These results help explain a deca...Soy Products a Double-edged Sword for Breast Cancer
...most active of the soy isoflavones, and because it activates estrogen receptors in cells, including some breast tumour cells. Dozens of studies of the role of human and plant estrogens in breast cancer have yielded seemingly contradictory findings. Some found that feeding genistein to female rats prior to p...Study Implicates Protein as a Trigger of Advanced Prostate Cancer Recurrence
...ology, and other Lineberger scientists. The kinase activates the receptor via phosphorylation by adding a phosphate group to this protein molecule. "This biochemical action converts a prostate cell that would need an androgen signal for its growth to one that is independent of the androgen signal," said sen...Suicide Gene Therapy Kills Bowel Cancer Cells
... is switched on, the virus produces a protein that activates an otherwise harmless prodrug, given separately. ... because the virus doesnt produce the protein that activates the drug unless it is inside a tumour. "The beauty of our approach is that the cancer cells are ma...Scientists Activate New Cancer Drug Using Light and Oxygen
...e selectively attacked using a PDT. When the light activates this new drug, it then works to produce a reactive form of oxygen, which destroys only the cells that have been marked by the cancer-fighting drug, thereby sparing other normal healthy neighboring cells. The process really is about controlling the...Sleep Apnea may Increase Risk of Diabetes
...apnea and diabetes, it is thought that sleep apnea activates the bodys fight-or-flight response. This triggers a cascade of events, including the production of high levels of the hormone cortisol that ultimately leads to insulin resistance and glucose intolerance, pre-diabetic conditions that, if left untreate...Genetic Code That Helps Kill Colon Cancer Cells Identified
... Institute of Genetic Medicine, suspected that p53 activates microRNAs like miR-34a, for various studies have demonstrated that these tiny RNA molecules are frequently abnormal in cancer cells. "P53 is one of the most commonly mutated genes in human cancers. And there is now a great deal of evidence that mic...Cannabinoids Regulate Inflammation Process
...'THC attaches itself to cannabin-oid receptors and activates them. In this way the active substance reduces the allergic reaction.' Incidentally, ointment like this would probably not have an intoxicating effect, for this the amount of THC contained would be much too small....Breast Cancer Drug Curbs Heart Disease.
...cking HER2 is different. We found that lapatinib activates a critical pathway that protects heart cells from ...d human heart muscle cells indicate that lapatinib activates a pathway that protects cardiac muscle cells from the death-promoting effects of mediators of inflam...Photodynamic Therapy can Scramble the Immune System to Fight Cancer Spread
...r one of these drugs has been injected selectively activates the drug in that area, treating the cancer but avoiding some of the side effects associated with chemotherapy. Researchers from the Roswell Park Cancer Institute in the US have now shown that one particular form of PDT might have the potential to d...Vitamin Extends Life in Yeast, Dartmouth Medical School Researchers Find
...am found that providing a newly discovered vitamin activates the yeast anti-aging gene product Sir2, which resembles sirtuins found in humans. The new work builds on Brenner’s prior discovery of the vitamin, termed NR (nicotinamide riboside), a natural product found in milk. Like the B3 vitamin, niacin, NR is ......LiveScience. It is yet to be seen how the parasite activates such fertility. Weeks is speculating on the fact that maybe, it produces some nutritional benefit in the host. Remarkable evolutionary changes usually millions of years but here in this aspect it has taken only 2 decades which is quite dramatic.” T...A New Pill to Burn Away Unwanted Fat
...e switch called PPAR-delta. Turning on this switch activates the same fat-burning process that occurs during exercise. Lead researcher Dr Ronald Evans believes the same will occur in humans. UK expert Dr Fredrik Karpe, from the Oxford Centre for Diabetes, Endocrinology and Metabolism, is hoping to test t...Marijuana Helps to Combat Lung Cancer
...and inflammation. THC seeks out, attaches to and activates two specific endocannabinoids that are present in high amounts on lung cancer cells, Preet said. This revs up their natural anti-inflammatory properties. Inflammation can promote the growth and spread of cancer. In the new study, the researchers fi...Alarming Rise of Methamphetamine Use Among Australian Youth
...mphetamine is a very addictive stimulant drug that activates certain systems in the brain. It is chemically related to amphetamine but, at comparable doses, the effects of methamphetamine are much more potent, longer lasting, and more harmful to the central nervous system (CNS). Street methamphetamine is ref...Glucose Causes Death of Brain Cells in Rodents Following Hypoglycemic Coma
... damage: the sudden return of glucose to the brain activates the enzyme NADPH oxidase, which in turn initiates a process of oxidative stress that is fatal to neurons. Oxidative stress occurs when cells are poisoned by highly reactive forms of oxygen. Previously, it had been assumed that oxidative stress in n...Canadian Researchers Raise Hopes of Treatment for Memory Loss
...inutes to hours. But intense, repeated training activates mechanisms in the brain, which stabilize nerve connections. Thus long-term memories lasting days, weeks or years are formed. GPL/M...Inhibiting Blood to Save the Brain
...amage in MS, but an active participant. Fibrinogen activates macrophage cells in the brain called microglia, causing inflammation which damages myelin. The scientists sought to design a therapeutic strategy that would block the damaging effects of fibrinogen without affecting its beneficial blood coagulation...Inflammation Promotes Metastasis of Prostate Cancer
... in the pathway that turns off the Maspin gene and activates the metastatic program. The new results also support the view that RANK ligand is a general promoter of prostate, and possibly breast, cancer metastasis. "Maspin is a very potent inhibitor of metastasis; in a patient with metastasis, cells have fo...... in the pathway that turns off the Maspin gene and activates the metastatic program. The new results also support the view that RANK ligand is a general promoter of prostate, and possibly breast, cancer metastasis. 'Maspin is a very potent inhibitor of metastasis; in a patient with metastasis, cells have fo...