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Tag: "activates" at medical news

Chemical Injections for Fat Removal

...rs describe a mechanism they found by which stress activates weight gain in mice, and they say this pathway ...the receptor (neuropeptide Y2 receptor, or Y2R) it activates in two types of cells in the fat tissue: endothelial cells lining blood vessels and fat cells themse...

New Oncogene for Brain Cancer

...ings, this led the team to hypothesize that IGFBP2 activates the Akt pathway, which they confirmed in subsequent lab experiments. In a final experiment, they treated IGFBP2-PDGFB infected cells in culture with a known Akt inhibitor, which killed more of the combination cells than those infected only with pla...

Scientists Discover Key to Manipulating Fat

...rs describe a mechanism they found by which stress activates weight gain in mice, and they say this pathway -- ...a neurotransmitter (NPY) and the receptor (Y2R) it activates in the fat tissue: endothelial cells lining blood vessels and fat cells themselves. In order to add ...

Parkinsons Disease Mechanism Identified

...gy. In earlier studies, they had found that MPTP activates protein-snipping enzymes called calpains in mitoch... researchers found that treating neurons with MPTP activates Cdk5 to switch off Prx2. Whats more, they found that activating Prx2 in MPTP-treated mice prevented ...

Bak Protein Sets Stressed Cells on Suicide Path

...en something happens that overwhelms the cell, it activates Bak and Bax to start cell death," says Mr. Brooks. "Some of the same proteins, cytochrome c is the big one, are needed for daily mitochondrial function like making energy, but if they are released from the mitochondria, they activate a cell ki...

Cytokine IL6 as a New Chemotherapeutic Target for Ras-driven Cancers

...couraging. "Targeting secreted proteins that Ras activates has opened the door to inhibit the oncogenic signal of Ras via druggable proteins," states Dr. Counter....

Tumor Painting to Fight Against Cancer

...avoid removing normal tissue. Chlorotoxin:Cy5.5 activates within hours and it begins binding to cancer cells within minutes. The Chlorotoxin:Cy5.5 signal lasts for 14 days, illuminating cancer cells. Contrast agents currently in use only last for a few minutes. I feel fortunate to be working with gifted s...

Researchers Find New Target for Anti-cancer Drugs

...drugs, we tried to determine if something that ras activates could be a possible target for a drug or therapy, said Christopher Counter, Ph.D., associate professor of pharmacology and cancer biology and senior member of the research team. We found a specific target that could be susceptible to drugs, and if ...

Group Therapy and Willpower can Help Smokers to Quit

...nfluences the brain's metabolism." The substance activates the brain's reward mechanisms and releases "feel-good" chemicals. As a result, smokers who do not light up just feel bad. Studies show that most habitual smokers only need to smoke one cigarette to find their emotional equilibrium. They have become...

Protein That may Prevent Eye Damage in Premature Babies Identified

...t UF's McKnight Brain Institute found that IGFBP-3 activates stem cells and other reparative cells of the bone marrow and the lining of blood vessels. Researchers from Harvard Medical School and the University of Goteborg in Sweden arrive at fundamentally the same conclusion in this study, identifying the pr...

Researchers Have Found the Role of Protein in Accelerating Breast Cancer Progression

... The new study identified PTN as one factor that activates stromal cells-cells found in the loose connective tissue-and induces several features of aggressive breast cancer. While the importance of these cancer cell-stromal cell interactions is well established, only limited progress has been made in identif...

Research Studies on Molecular Switches of Gene

...make the specific protein for which it codes. CREB activates genes in response to a molecule called cAMP, which acts as a messenger for a variety of stimuli including hormones and nerve-signaling molecules called neurotransmitters. The St. Jude team showed that each gene that responds to CREB chooses which c...

Protein Targets for Carcinogenesis

...to attach Ub to another protein: E1, E2 and E3. E1 activates Ub and transfers it to E2, which in turn cooperates with an so-called Ub ligase (E3) that couples Ub to a specific target protein. However, Dikic and colleagues discovered that certain proteins can be ubiquitinated independently of E3 ligases which c...

A New Signaling Mechanism in Drosophila

...or of the study, explains that the torso-like gene activates a membrane receptor molecule that is specific to Drosophila, but that the molecule belongs to a receptor family (that includes, for example, the human growth factor), which also reacts when it receives an external signal. This research describes a ...

Living With Stress

...d what causes this? Our stress response - that activates the release of stress hormones into our blood stream! It is only when extreme stress begins to affect an individual-physically or psychologically- that it becomes a cause for concern. Nevertheless, in the present time, stress has a negative connot...

RNA Play a Vital Role in Gene Activity

...pression." They have one clue: HOTAIR binds to and activates a group of enzymes called the Polycomb Repressive Complex 2 that modifies histones and helps them wind up the DNA. The researchers' interest is more than just theoretical. Polycomb proteins are improperly regulated in some types of cancers. HOX gen...

Stressed Mice may Hold Clue to How Fat is Stored: Study

...rs describe a mechanism they found by which stress activates weight gain in mice. By manipulating this pathway, they said they were in fact able to selectively add fat to their test subjects. "We couldn't believe such fat remodeling was possible, but the numerous different experiments conducted over four yea...

Useful Parasites

...LiveScience. It is yet to be seen how the parasite activates such fertility. Weeks is speculating on the fact that maybe, it produces some nutritional benefit in the host. Remarkable evolutionary changes usually millions of years but here in this aspect it has taken only 2 decades which is quite dramatic. Th...

Vitamin Extends Life in Yeast, Dartmouth Medical School Researchers Find

...am found that providing a newly discovered vitamin activates the yeast anti-aging gene product Sir2, which resembles sirtuins found in humans. The new work builds on Brenners prior discovery of the vitamin, termed NR (nicotinamide riboside), a natural product found in milk. Like the B3 vitamin, niacin, NR is a...

Diet for Autism

...tion. Another theory postulates that the leaky gut activates a negative immune response. Surveys reveal that nearly all the autistic children are placed on a diet, at some stage or the other of their life, with the fervent hope that selective abstinence will do them good. There are validations from va...

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