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Tag: "tamoxifen" at medical news

Cost-effective Treatments for Breast Cancer

...n receptor positive breast cancers, switching from tamoxifen to the oral steroidal aromatase inhibitor exemesta...erapy. A recent study showed that switching from tamoxifen to exemestane after two to three years of tamoxifen significantly improves disease-free survival com...

New Adjuvant Breast Cancer Treatments Found Cost-effective

...n receptor positive breast cancers, switching from tamoxifen to the oral steroidal aromatase inhibitor exemesta...erapy. A recent study showed that switching from tamoxifen to exemestane after two to three years of tamoxifen considerably improves disease-free survival comp...

Women With Atypia Nearly Eight Times More Likely to Develop Breast Cancer

... adviced to consider defensive medications such as tamoxifen or other risk-reducing approaches. However, questions remained from previous research on whether a positive family history further increases risk in women with atypia and for how long the increased risk in women with atypia lasts. The most commonl...

Researchers Identifies Molecules That is Effective in Fighting Against Breast Cancer

...t cancer is the most common cancer among women and tamoxifen is the preferred drug for estrogen receptor-positi...ny of these cancers are intrinsically resistant to tamoxifen or acquire resistance during treatment. Consequently, there is an ongoing need for breast cancer dru...

Chemo Brain- Nothing Forgettable About It

...herapy and supplementary hormonal treatments, like tamoxifen or aromatase inhibitors that lower the amount of estrogen in women who have cancers fueled by female hormones, as well as early-onset cancer that catapults women in their 30s and 40s into menopause. There are other suggestions got from various stu...

Researchers Have Identified Subgroup Sensitive to the Drug Cisplatin

...erone, and in recent years antiestrogen drugs like tamoxifen have improved outcomes for women with those tumors. About 20 to 30 percent of tumors, some with hormone receptors, have elevated levels of a growth-promoting protein called HER2, and those tumors are candidates for treatment with the monoclonal antib...

Combining Therapies can Improve Survival for Early-stage Breast Cancer Patients

... cancer who are treated with both chemotherapy and tamoxifen have a higher survival rate than patients who receive only tamoxifen//. But a combination of tamoxifen and ovarian suppression—treatment to stop the ovaries from functioning—did not show any additional b...

Breast Cancer? ER Positive or Negative

...able to at least two important factors: the use of tamoxifen after surgery, which substantially reduces the risk of recurrence in ER-positive tumors only; and widespread use of screening mammography, which is more likely to detect the slow-growing tumors that tend to be ER-positive,' said Ismail Jatoi, MD, PhD...

Tamoxifen Yields Long-term Reduction in Breast Cancer Risk

...isk of breast cancer. However, most of the data on tamoxifen for breast cancer prevention comes from the period... little information about breast cancer risk after tamoxifen use is stopped. Tamoxifen, an antiestrogen drug, is only active on estrogen receptor (ER)-positive b...

New Drug Therapy for Breast Cancer Offers Hope

... a full five years of tamoxifen, or treatment with tamoxifen followed by exemestane. Giving women tamoxifen after surgery already reduced the risk of dying by 33 per cent compared with no treatment. After ano...

Early Switch to an Aromatase Inhibitor Increases Survival

...uce the risk of breast cancer recurrence. However, tamoxifen is associated with increased risk of death from ot...strokes and endometrial cancer. Despite this risk, tamoxifen and another drug in this class, raloxifene, remain an extensively used and popular treatment. Aro...

Hormone Drug Type Makes Survival Difference in Advanced Breast Cancer

...ancer treatments that also affect estrogen include tamoxifen and progestins. Tamoxifen is the most widely used hormonal treatment in advanced breast cancer; however, it carries a risk of blood clots and other rare but potentially serious side effects. Bliss said that the review found very little reliable dat...

Cancer Recurrence in Older Breast Cancer Patients Reduced By Radiation Therapy

...ectomy// and five years of treatment with the drug tamoxifen can dramatically reduce the risk of both cancer recurrence and new tumors in older women with early breast cancer. "While these treatments are standard care for younger patients, it is has been shown that older women are less likely to receive the...

Tamoxifen Discontinuation Rates Surprisingly High

...o reveals that over one third of women have ceased tamoxifen treatment. In the clinical practice setting alm... a quarter of women treated for breast cancer stop tamoxifen within one year, a rate twice as high as indicated by previous studies. Tamoxifen is a selective est...

Breast Density and the Risk of Cancer

...o elevate breast density. It is here that the drug tamoxifen can help in reducing breast density. "Now we can also incorporate a woman's breast density to help inform the decision as to whether or not one should take tamoxifen," said Dr. John Mackey of the Alberta Cancer Board in Edmonton....

Selective Marker Found to Indicate Aggressive Form of Breast Cancer

...inates several important lines of therapy, such as tamoxifen or Herceptin, that work well for other breast cancer subtypes. 'Currently, there is no direct means of determining if a breast cancer is a basal epithelial tumor – doctors only know for certain once the other forms of breast cancer are ruled out,'...

Selective Marker Found to Indicate Aggressive Form of Breast Cancer

...inates several important lines of therapy, such as tamoxifen or Herceptin, that work well for other breast cancer subtypes. 'Currently, there is no direct means of determining if a breast cancer is a basal epithelial tumor – doctors only know for certain once the other forms of breast cancer are ruled out,'...

Seven Things You Should Know About Breast Cancer Risk

...s. Chemoprevention. Taking the anti-estrogen drug tamoxifen or raloxifene may cut the incidence of breast cancer in women at increased risk for the disease. Source-Newswise SRM...

Study Identifies Mechanism Which May Help Tamoxifen Work Better

...esistant to the breast cancer drug tamoxifen. “For tamoxifen to work better, you need to inhibit the Notch pathway,” said co-author Dr. Kathy S. Albain, professor, division of hematology/oncology, department of medicine, Loyola University Chicago Stritch School of Medicine. “This can be done by using a nove...

New Study Shows Efficacy of AROMASIN on Early Breast Cancer

...t cancer who received Aromasin after five years of tamoxifen were 56% less likely to have a relapse of breast c... cancer free, having completed about five years of tamoxifen therapy – the standard treatment at the time of the start of the trial. Patients were randomly assig...

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