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Tag: "spectrometry" at medical news

Detection of Cancer

...of the test, C-Test1, uses a technique called mass spectrometry to search for the diagnostic molecule, which seems...nique to identify the type of cancer present."Mass spectrometry may enable us to identify a molecular 'signature' unique to each cancer and therefore give us a way ...

A new test to detect pregnancy risks

...nnecticut and his associates by using imaging mass spectrometry obtained the details of the proteins present in the amniotic fluid. These were obtained from women who delivered pre-term babies. The researchers identified 13 proteins associated with inflammation of the amniotic fluid. Then they identified four i...

Mass Spectrometry to Identify Viruses

Although mass spectrometry has been used to determine the chemical compositio... Applied and Environmental Microbiology. In mass spectrometry is essentially a laser turns a sample into ionized particles, which are then accelerated in a vacuum...

Antarctica: The story behind the ice

...s using a technique called thermal ionization mass spectrometry revealed the teeth neodymium had a signature of the Pacific, indicating at least a surface connection between the oceans. The presence of neodymium with a Pacific signature in the deep Atlantic suggests that Pacific surface waters flowed into the Sou...

Cell Survival Depends on Chromosome Integrity

...tational approaches, proteomics technologies, mass spectrometry technologies, single-cell profiling and other novel methods to detect, quantify and monitor lysine modifications on DNA-coiling histones. Histone modifications are critical for many biological processes, such as epigenetic control of gene expression,...

A Mushroom Extract May Impact the Body’s Immune Syste

...ing both low-performance and high-performance mass spectrometry (MS). Statistical analyses of low- and high-resolution MS data were cross-validated to determine whether changes in immunologically relevant proteins occurred that were attributable to treatment with the mushroom extract. ResultsStatistical analysi...

Brain protein expression can be damaged with prolonged alcohol exposure

...es known as 2-D electrophoresis and MALFI-TOF mass spectrometry were used to identify proteins in the central nervous system that showed increased or decreased expression. The photographs showed that after a week of alcohol exposure, the fish became less clustered and occupied a larger area of the tank. However...

New And Improved Blood Test For TB Developed

...ical Research, said, “Current developments in mass spectrometry together with new statistical methods for pattern discovery are allowing us to identify biomarkers of infection.” He further said, “Our work opens the door to further research into translating these findings to fast and reliable methods of detecting ...

Plague Proteome Reveals Proteins Linked to Infection

... techniques called accurate mass and time tag mass spectrometry and clustering analysis to compare abundance changes in 992 proteins under four different growth conditions, at 26 degrees and 37 degrees Celsius and with and without calcium. They found 89 candidate proteins with similar abundance changes to 29 kn...

New Technique to Identify Bacteria for Food Safety

...stant professor of biochemistry; and Cooks. Mass spectrometry works by turning molecules into ions, or electrically charged versions of themselves, inside the instrument's vacuum chamber. Once ionized, the molecules can be more easily manipulated, detected and analyzed based on their masses. The key DESI innova...

Tears Reveal Some of Their Deepest Secrets to Researchers

...ry. They used a technique called electrospray mass spectrometry to differentiate between the different lipid compo...s of lipids in the tear film, but advances in mass spectrometry technology are improving research efforts. “Other scientists used different techniques to try to d...

More Support for Zinc-antiatherogenic Link

...They used isotope dilution gas chromatography-mass spectrometry techniques to measure biomarkers of oxidative lipid damage in atherosclerotic rabbit aorta. In the past the research team used F(2)-isoprostane measurement. But since analysis of different biomarkers often requires different protocols, it adapted ...

"Pre-treatment Blood Test" A New Guide to Lung Cancer Therapy

...e Oncology Group protocol. At the time of the mass spectrometry analysis and classification, the researchers were blind to the survival status of the patients. We classified the patients as being either likely to benefit (good) or not likely to benefit (poor) from the TKIs, Carbone said. The method was highly s...

Clinical Outcomes of Nonsmall Cell Lung Cancer Patients can Be Classified by New Algorithms

... with nonsmall-cell lung cancer (NSCLC) using mass spectrometry techniques . Currently, clinicians do not have adequate methods for determining which patients will benefit from treatment with certain drugs. The new models could help physicians decide who will benefit from certain treatment options. The studies ...

Genetic Cause of Inherited Eye Diseases Identified

...analyses for this study. The researchers used mass spectrometry to identify and measure the amounts of proteins in mouse photoreceptor sensory cilia. They found many proteins in the cilia that had not been identified in photoreceptors before. This includes proteins involved in intraflagellar transport, which is a...

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