Biologics valuable treatment option for patients with inflammatory bowel disease
... management of inflammatory bowel disease has been significantly affected by the development of biologic therapies,” according to Dr. Hanauer. “Biologic therapies provide new options and hope for many patients, however they may be accompanied by serious side effects, both when used alone or in combination with oth...A new century of Alzheimer's disease research
... meant that a compound that could successfully and significantly lower AB42 must be one without such severe side effects. So, the first NSAIDs that Drs. Golde and Koo screened were known as COX2 inhibitors because they were believed to be safer. (NSAIDs reduce inflammation because they target enzymes that are know...White Blood Cell Booster May Help Cancer Patients Avoid Deadly Complications
...wth of infection-fighting white blood cells may be significantly less likely to die from a chemotherapy-related complication characterized by fever and low white blood cell levels, according to a multi-institutional study led by researchers from the University of Rochester School of Medicine and Dentistry and the ...One-third of Adults Have Had Some Form of Alcohol Use Disorder During Their Lifetimes
... were alcohol-dependent. "Alcohol dependence was significantly more prevalent among men, whites, Native Americans, younger and unmarried adults and those with lower incomes. Current alcohol abuse was more prevalent among men, whites and younger and unmarried individuals while lifetime rates were highest among mi...Electric Field Therapy to Zap Cancerous Tumours
...ividing cells. The study found that the therapy significantly slowed the growth of tumours as well as increased survival rates. Previously, patients with advanced glioblastomas could expect to live on average six months or less. With the therapy, the average reprieve was more than a year, and three of patients ...Blood Protein may Hold Key to Why Healthy People Get Heart Attacks
...rs found that the average blood levels of MPO were significantly higher in those who developed heart disease than in those who remained healthy. The study suggested that although MPO is intended to kill harmful bacteria, it might instead inflame the body's arteries and cripple protective substances in the blood...Rosehips may Be an Effective Alternative for Rheumatoid Arthritis
...ally, the overall tenderness of painful joints was significantly reduced in patients given the supplement, and quality of life greatly improved. Stefan Willich, from the Charite University Medical Centre in Berlin, who co-led the study, said: "I think we were all surprised to see such meaningful results. Rheumat...Alcohol Abuse, Addiction Hits 3 of 10 Americans
...pendence was 29.8 years. "Alcohol dependence was significantly more prevalent among men, whites, Native Americans, younger and unmarried adults and those with lower incomes," the study's authors wrote in a summary of the study, which is published in the July issue of Archives of General Psychiatry....Adult Stem Cells Show Promise for Peripheral Vascular Disease
...toms, including lower limb pain and coldness, were significantly improved in 137 (90.1%) of the patients; limb ulcers improved or healed in 46 (86.8%) of the 53 patients, while 25 of the 48 (47.9%) patients with limb gangrene remained steady or improved. Angiography (an X-ray) before treatment, and at 12 weeks aft...Skin Rashes Signifies Longer Survival in Cancer Patients
...d that overall survival in these patients was also significantly longer (a median of 8.2 months compared to 4.7 months), compared to placebo patients who didn't develop a rash. "We don't know why some patients treated with a placebo developed a rash, but it could be due to the strength of their immune system, and ...Epilepsy Increases Suicide Risks
...y when the seizures are uncontrolled, suicides are significantly higher." The most common cause of death associated with epilepsy, said Dr. Sperling, is "unexplained death in epilepsy, which is responsible for 15% to 50% of the excess deaths in these patients. Typically, these patients are found dead in their be...Anti-depressants Do Not Increase the Overall Risk of Most Birth Defects
...), anti-depression drugs , during pregnancy do not significantly increase the overall risk for most birth defects. However, each study found that taking SSRIs during pregnancy is associated with a small increase in the risk of certain rare birth defects but they are different birth defects. The studies show h...Great Lakes Fish in Canada Heavily Polluted
...ealth is threatened, it said, calling for steps to significantly reduce pollution emissions in the Great Lakes basin and deal with the continuing legacy of dangerous chemicals, such as PCBs, once used electrical equipment but banned in 1970s. Even though PCBs have not been used for decades, they are still being fo...Cat Exposure Increases Bronchial Responsiveness
...even moderate exposure to cat allergen resulted in significantly greater responsiveness. Among people with any sensitization, the difference in BR between those who had low versus high exposure to cat allergen was almost as great a difference as that between non-asthmatic and asthmatic individuals in the United ......ost advanced stage of glioma, gliobastoma, has not significantly improved for decades, note Zhang and Fuller. We hope IGFBP2 will provide an effective target for treatment of this devastating disease. Sarah Dunlap, a student in the Graduate School of Biomedical Sciences jointly operated by M. D. Anderson and The...Use of Implantable Cardioverter Defibrillators Canada Lags Behind U.S
...efibrillators in Canada is rising, but it is still significantly less than that in the United States. Dr. David Birnie and colleagues from the University of Ottawa Heart Institute report that, between 1995 and 2003, the use of implantable cardioverter defibrillators in adults who survived a cardiac arrest increas...Insight Into Neural Stem Cells Has Implications For Designing Therapies
...ific types of neurons. The finding, the team says, significantly shifts the perspective on how these cells could be used to develop cell-based brain therapies. The results of their study are reported online in "Science Express" today, July 5, and will be published in an upcoming issue of "Science." Adult neura...New Spinal Cord Stimulation System Launched
...ling programming improvements that are designed to significantly impact patient outcomes and clinical results." EGL Scan (Electronically Generated Lead Scan) technology displays the relative position of implanted leads, within seconds and without using fluoroscopy or x-ray. The information from EGL Scan can be u...DNA Sample Suggests Greenland was Much Warmer During Last Ice Age
...t we've learned is that this part of the world was significantly warmer than most people thought,' said Martin Sharp, a glaciologist at the University of Alberta and a co-author of the paper appearing in the journal Science. Sharp said the sample suggested that the temperature of the southern Greenland boreal fo...... prescription costs for men over the age of 65 is significantly higher than it is for women. The primary object... of age, the mean prescribing costs for males were significantly higher than females. On average, costs for a 75-year-old man would be 12 times the costs for a 25-...