receptor 1 1

Tag: "receptor" at medical news

New drug to treat Heart Attack and damaged tissue

...y, such as the stimulation of chemokines, adhesion receptor molecules, procoagulants and permeability – related genes. By deleting Egr-1 gene, the tissue injury level decreases and it enhances oxygen function and survival of the subject...

ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer

...been shown that ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, has confirmed, durable responses and safety in patients with advanced non-small cell lung cancer (NSCLC) as monotherapy and in combination with standard chemotherapy agents after segmental scrutinization in two different st...

Soluble IL-4 Receptor - A new boon for asthmatics

...ing avenged by a new drug. A soluble interleukin-4 receptor (IL-4R), which acts as an IL-4 antagonist, appears...nd were divided into two groups. In one group IL-4 receptor were given and to the other group placebo was given. It was found that, after a 12-week trial, thos...

New FDA Approved Drug To Treat Migraine

...s to a class of drugs known as selective serotonin receptor agonists.Axert tablets contain almotriptan malate, a selective 5-hydroxytryptamine receptor agonist.// This drug targets serotonin receptors and act against migraine headaches by inducing the...

Medications to Prevent Relapse to Cocaine Use

...ng relapse to cocaine use. By blocking cannabinoid receptor activity with chemical antagonists, the investigators prevented relapse to cocaine use induced by exposure to cocaine-associated cues or by cocaine itself. This finding could open up a new avenue for the development of drugs to prevent relapse to...

Snake venom a treatment for digestive disease

...dition, the researchers found a site that may be a receptor on the surface of intestinal muscle cells. This site had a chemical structure that may be able to bind with the proteins in the laboratory, indicating that the prokineticins could control muscle cells' movement through a receptor. The researchers n...

Too much coffee is too bad

...ho were homozygous for a mutation in the vitamin D receptor (VDR) gene were at greater risk for caffeine-related bone loss.// Women in the high cafeeine category with the tt genotype lost bone density over 3 years, compared with no change in bone desity in women in the low caffeine group.Though the number of...

ZYDUS enters female health care segment

...isk of fractures. Bonmax is a selective estrogen receptor modulator. It maximises bone mass thereby reducing the risk of breast cancer and decreases total and LDL cholesterol. Currently international trials are on to explore its use as a drug to prevent and treat breast cancer. Bonmax comes to India with ...

Control of inflammation

...y activity abates. Adenosine and its membrane-bund receptor made attractive cnadidates for signal and sensor, Sitkovsky notes. A simple molecule that leads a busy life, adenosine is the core of the cell’s energy-containing compound, ATP, and elevated levels of it in the brain appear to cause sleep. Despite i...

Combination therapy to treat breast cancer

...actors receptors, HER2 and epidermal growth factor receptor (EGFR). Previous research has shown that these growth factor receptors are involved in 20 and 70 per cent of breast cancers, respectively, and it has been suggested that they interact with one another to ensure cell proliferation and survival. Trast...

Nose plug-switch that stops smelling

...rotein called CNGA4 helps plug the ‘nose’ of odour receptor cells.//The main job of these reurons is to detect smells and send that information to the brain as an electrical signal.The ‘nose’ is really a channel in the neurons’ membrane that opens when an odour is presented and closes as the neuron becomes de...

Comprehension of taste receptor

...ferent combinations of receptors, though the exact receptor mechanisms are still being sorted out.They have focused on T1R receptors, a family of proteins remotely related to receptors in the brain that recognise the amino acid glutamate and related chemicals.Different T1R genes can be expressed in cells in d...

Nose plug: switch that stops smelling

...rotein called CNGA4 helps plug the ‘nose’ of odour receptor cells.The main job of these neurons is to detect smells and send that information to the brain as an electrical signal. The ‘nose’ is really a channel in the neurons’ membrane that opens when an odour is presented and closes as the neuron becomes d...

Chemical in Gila monster's saliva yields Alzheimer drug

...ains a chemical which acts on a previously unknown receptor pathway in the brain that affects memory. New York-based biotechnology company Axonyx Inc., which is developing the drug, Gilatide, plans to start human trials with it as a treatment for Alzheimer’s disease later this year. A growing number o...

Gene variation simulates cholesterol response to oestrogen

...terol). The gene concerned is called the oestrogen receptor alpha and, in this study, 20 per cent of the women...rch is needed before genetic testing for oestrogen receptor alpha can be recommended for women considering HRT. But this study promises a way of detecting those...

Leptin connected to obesity blood clots

...mal mice. And mice with a deficiency in the leptin receptor - a protein necessary for leptin's function - also...e findings suggest that blocking the leptin/leptin receptor interaction might be a useful treatment in cutting the risk of heart disease and stroke among obese ...

Gene glitches connecting pot with Schizophrenia

...tly in the brain. The chemical, called cannabinoid receptor protein, studs the surfaces of brain cells and lat...e and his team examined the gene for the marijuana receptor in 115 Japanese patients with schizophrenia and an average age of 40.When they compared this gene in...

Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients

... about the effects of long-acting beta2-adrenergic receptor agonists, such as salmeterol, on inflammation. The clinicians enrolled 20 patients, between the ages// of 18 and 55, with mild stable asthma who were randomized to receive salmeterol (50 micrograms b.d), fluticasone propionate (250 micrograms b.d), o...

Treatment for cholesterol-related illnesses likely with the discovery of receptor in mice

...n humans may now be easier with the discovery of a receptor in the cells of mice that protects them from toxins. Researchers discovered the receptor during a study of cerebrotendinous xanthomatosis (CTX), a rare and often fatal disorder caused by ex...

Stroke victims have new hope with activated protein C

...o cellular receptors, called endothelial protein C receptor and protease-activated receptor 1, to reduce the level of p53 in damaged cells by 75 per cent. APC also increases anti-apoptotic sig...

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