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Tag: "inhibitor" at medical news

African HIV strains more resistant to anti HIV drugs

...ational Academy of Sciences.Comparing the protease inhibitor to a key and the protease to a lock, Dr. Freire said when there are new strains of the virus, the key will not fit the lock and hence it will be difficult to control the burgeoning AIDS situation in Africa. But he hopes that by adapting to the change...

Soluble IL-4 Receptor - A new boon for asthmatics

...monstrate the potential clinical efficacy of a TH2 inhibitor for the treatment of asthma," the investigators note. This soluble IL-4 receptor, which isn't a corticosteroid, selectivelyinhibits allergic mechanisms will be a new boon in the treatment strategy of asthma. "These data demonstrate the critical rol...

Iron supplements proves helpful in dry cough .

The ACE inhibitor is one of the most widely used drugs in cardiovascular medicine.It improves the survival rates and reducing complications in patients with cardiovascular conditions such as hypertension and heart failure.But however this drug produces dry cough as it...

Increased Heart Attack Risk From Celebrex,Vioxx

...ed by 14 million people last year. The other COX-2 inhibitor is Rofecoxib, sold as Vioxx. The drugs are popular because they provide the same pain- killing effects as aspirin and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen, but with less chance of causing ulcers and intestinal bleeding. ...

A new growth factor identified

...lity, such as the polycystic ovary syndrome and an inhibitor of EG-VEGF may have therapeutic value in this condition. He also added that the discovery also raises the possibility that other growth factors exist that act on specific tissues, such as the heart or lung or skeletal muscle, which could hold "consi...

New light on Cardiology

The angiotensin-converting enzyme (ACE) inhibitor ramipril, used for the treatment of hypertension, .../ The HOPE study compared the effects of the ACE inhibitor in addition to standard therapy with placebo and vitamin E in a sample of about 7,580 high-risk pati...

FDA Approves New HIV Drug, Viread

...he first nucleotide analogue reverse transcriptase inhibitor to be approved for treatment of HIV in the US. As a result//, it may offer a treatment option for patients whose infections have become resistant to currently available medications. Foster City, California-based Gilead said that the 300 milligram ta...

Garlic fights malaria and cancer

...lphide that naturally occurs in garlic, is a known inhibitor of glutathione reduction. ...

Beehives to curb caries

...uces dental plaque formation. Propolis is a potent inhibitor of glucosyltransferase (Gtf) enzymes, enzymes that synthesize glucans from sucrose and promote the binding of cariogenic bacteria to teeth, critical steps in the development of decay. This natural substance is actually used by bees to strengthen an...

Scios Inc. targets drug giants in arthritis war

... was forced to drop back after its lead p38 kinase inhibitor showed toxicity in high doses in some animals. There are also many competitors. They include drug giant GlaxoSmithKline, which first isolated the p38 kinase in the early 1990s. Glaxo's drug is in early stage clinical trials for rheumatoid arthritis, ...

Researchers trick Alzheimer's Enzyme

...chiatric diseases." Molecular drug designers make inhibitor molecules that fit snuggly into the active sites of target enzymes, blocking their action on other molecules. Many diseases -- cancer, AIDS, Alzheimer's, arthritis and anthrax, for instance -- induce unnatural functions in enzymes. Inhibiting enzyme ...

A ray of light on Cardiology

The angiotensin-converting enzyme (ACE) inhibitor ramipril, used for the treatment of hypertension, .../ The HOPE study compared the effects of the ACE inhibitor in addition to standard therapy with placebo and vitamin E in a sample of about 7,580 high-risk pati...

Hypertension drugs could lower Disability

...ging in Bethesda, Md. The women on continuous ACE inhibitor therapy showed slower loss of walking speed and mu...rds, the researchers found women on continuous ACE inhibitor therapy had a lower average decline in muscle strength of 2.5 pounds over the three years, as compar...

Beehives to curb dental caries

...uces dental plaque formation. Propolis is a potent inhibitor of glucosyltransferase (Gtf) enzymes, enzymes that synthesize glucans from sucrose and promote the binding of cariogenic bacteria to teeth, critical steps in the development of decay. This natural substance is actually used by bees to strengthen an...

Blood pressure control with ACE inhibitor or diuretic?

...iovascular disease was 11 percent lower in the ACE inhibitor group. Study author Dr. Christopher M. Reid of th... that their study recommended starting with an ACE inhibitor and then using a diuretic, if one is over the age of 65, while the ALLHAT study recommended starting...

Common Cold Remedy May Treat SARS

... the protease. Researchers hope to find a protease inhibitor against SARS soon. However developing a safe drug may be taking time. Meanwhile, researchers in New York have announced they may be making progress in developing a drug that prevents the SARS virus from entering cells. One need to note that SARS has ...

Lowering Risk of Breast Cancer Recurrence

... from fatty tissues. He says by using an aromatase inhibitor like exemestane, that small residual amount of estrogen is even further reduced. Dr. Cole says, "You're taking low estrogen and you're making it even lower. Now, why does that matter? Well, breast cancer cells that are hormone-sensitive can sense eve...

Drug Effective for Vascular Dementia

...stigators studied the effect of the cholinesterase inhibitor donepezil on people with a probable or possible diagnosis of VaD. About 600 patients with an average age of 75 took part in the study. Patients were randomized to receive the drug in one of two doses -- five milligrams once a day or 10 milligrams onc...

Link Between Alcohol Consumption And Cardiovascular Disease

...factor-alpha (TNF-alpha) and plasminogen activator inhibitor (PAI-1). Results show moderate drinkers had the lowest levels of IL-6 and CPR in comparison to non-drinkers. However, those who consumed high levels of alcohol had higher levels of IL-6 and CPR in comparison to non-drinkers and moderate drinkers. ...

Drugs Taken During Pregnancy Found To Affect Unborn Babies

...hers found that women who use a serotonin reuptake inhibitor (SSRI) to treat depression or other psychiatric problems during pregnancy may be putting their infants at risk for neurobehavioral problems. For the study researchers studied 17 full-term newborns whose mothers had taken an SSRI during pregnancy an...

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