Contraceptive Spray Shows Positive Clinical Trial Result
...ve skin sprays, each containing a progestin and an estrogen . The first study was a Phase I, pharmacokinetic study, investigating the delivery of a formulation combining Nestorone and the synthetic estrogen, Ethinyl Estradiol. A single dose of the combination formulation was applied to the forearm of health...Liver Cancer More Prevalent in Males
...d cells in the liver that produce IL-6 showed that estrogen acts on these cells to suppress IL-6 production. A similar mechanism may account for the gender bias in liver cancer in humans, according to the researchers. Their discovery could lead to development of therapies to reduce development of liver canc...Hormone Replacement Therapy Liberation at a Cost
... HRT is a means of replacing the sex hormones estrogen and often progesterone for post-menopausal women. The two major female hormones estrogen and progesterone control the female reproductive system and have an effect on many systems and tissu...Afro- American Women Have More Aggressive Breast Cancer
...mmel Cancer Center at Jefferson. Such tumours lack estrogen and progesterone receptors, resulting in a lack of effectiveness of the commonly used breast cancer drug tamoxifen. The tumours also lack the HER2-neu receptor protein, rendering the drug Herceptin ineffective as well. While African American women ...Study Links Breast Cancer to Western Diet in Chinese Women
...was linked to more than double the risk of getting estrogen receptor positive (ER+) breast cancer, one of the ...st-menopausal women, especially heavier women with estrogen receptor-positive tumors," she said. "Our study suggests the possibility that the 'meet-sweet' pat...Study Links Breast Cancer to Western Diet in Chinese Women
...was linked to more than double the risk of getting estrogen receptor positive (ER+) breast cancer, one of the ...st-menopausal women, especially heavier women with estrogen receptor-positive tumors," she said. "Our study suggests the possibility that the 'meet-sweet' pat...Src Inhibitors in Breast Cancer Therapy
Estrogen, which binds estrogen receptor alpha (ER-alpha), is a risk factor for br...sitive breast cancers, and have been thought to be estrogen independent. In a study appearing online on July 12 in advance of publication in the August print ...Kerala Institute to Hold International Seminar on Drug Discovery
...of ligands and focused library design of selective estrogen receptor. Modulators using combinatorial docking method, quantum mechanics in structure based drug design, novel methods to predict protein conformational changes during ligand binding are included for deliberations. Jorg Weiser, vice president, ...Genetic Variation may Increase Premenstrual Depression Risk
...morphisms, in one of the two genes that encode the estrogen receptor. The variants, which are differences in s... nucleotides A, G, C, or T, were identified in the estrogen receptor alpha gene, ESR1. The scientists found that compared to the control group, women with PMD...Bone Health Protection by Dietary Calcium
...bone mineral density and urinary concentrations of estrogen metabolites." The researchers found that the wom... intake at 1,620 milligrams per day. The hormone estrogen is known to maintain bone mineral density. But the standard form of estrogen is broken down or metab...Women Taking Oestrogen Therapy Showed Reduced Coronary Artery Calcification
...lts showed that in these younger menopausal women, estrogen therapy reduced calcified plaque buildup in the ar...ern California. These data support initiation of estrogen therapy, where indicated when a woman first enters menopause and begins experiencing symptoms and bo...Cost-effective Treatments for Breast Cancer
...y breast cancer. In a Canadian economic study of estrogen receptor positive breast cancers, switching from tamoxifen to the oral steroidal aromatase inhibitor exemestane (trade name: Aromasin) extended disease free survival at a minimal cost per person. In another of study of human epidermal growth factor r...New Adjuvant Breast Cancer Treatments Found Cost-effective
...y breast cancer. In a Canadian economic study of estrogen receptor positive breast cancers, switching from tamoxifen to the oral steroidal aromatase inhibitor exemestane (trade name: Aromasin) enlarged disease free survival at a minimal cost per person. In another of study of human epidermal growth factor...Estrogen Therapy Protects Against Fading Mental Powers: Study
...placement therapy (HRT). The study suggests that estrogen protects the neurons in the post-menopausal female...fore menopause when production of the sex hormones estrogen and progesterone begins to ease off. The findings indicate that the debate on the potential benefi...Testosterone Cream Ineffective in Enhancing Libido in Female Cancer Survivors
...y and increased sex drive in women with sufficient estrogen levels, this new study was conducted on 150 post m... the testosterone cream could be attributed to low estrogen levels among the women who took part in the study, researchers said, "If providing supplemental estr...Researchers Identifies Molecules That is Effective in Fighting Against Breast Cancer
...mong women and tamoxifen is the preferred drug for estrogen receptor-positive breast cancer treatment. Many of these cancers are intrinsically resistant to tamoxifen or acquire resistance during treatment. Consequently, there is an ongoing need for breast cancer drugs that have different molecular targets. ...Estrogen May Be a Good Therapy for Women Before They Turn 65
...ht be a double blessing for those women who are on estrogen therapy before the age of 65. Recent research has... The study showed that women who took any form of estrogen hormone therapy before the age of 65 cut their risk of dementia by 50%, as compared to women who wer...Study to Investigate Gene's Effect on Bone Loss in Breast Cancer Patients
...cer are often prescribed a drug that reduces their estrogen levels. But because estrogen is important to bone health, there is widespread concern about how the estrogen-reducing drugs - ca...Operation on Pillow Angel Violated Laws, Says US Advocacy Group
...st buds were removed, and she received a high-dose estrogen therapy. As a result, Ashley was frozen as a child. She attained her full growth at 4 feet 5 inches and 75 pounds, with no reproductive capacity. Ashley's parents say that compassion, not convenience of care, was their motive. Writing on their bl...Estrogen is Important for Bone Health in Men as Well as Women
...es of osteoporosis are numerous, but in women, low estrogen levels after menopause have been considered an imp... in St. Louis has shown that low amounts of active estrogen metabolites also can increase their osteoporosis risk. "Most people don't think about estrogen in ...