African HIV strains more resistant to anti HIV drugs
...difficult to latch on to the protease, which is an enzyme useful in the replication of the virus inside the body. If the drug attaches itself to the protease, then it is easier for the drug to deactivate the virus. This is difficult in two African strains called A and C subtypes of HIV, the researchers say...A ribozyme, an enzyme that can be used to kill the deadly Hepatitis E virus has been designed by Indian scientists.The ribozyme had been designed using the viral clones and would kill the virus by cutting RNA. The efficacy of the ribozyme was being tested on animal...Iron supplementation for a common side effect
... pressure medication. The angiotensin-converting enzyme (ACE) inhibitors are often used to treat high blood pressure, heart failure and other cardiac conditions. But up to 40% of people on ACE inhibitors are troubled by a cough. The side effect is not considered serious by doctors, but it is the most comm...... found a previously unknown chemical site on a key enzyme that regulates production of the genetic messenge...NA.In a series of complicated experiments with the enzyme from the bacteria E.Coli. Erie and her students found that when the precursor molecule does not occu...Iron supplements proves helpful in dry cough .
...for patients suffering from angiotensin-converting enzyme (ACE) inhibitor-induced dry cough. Kyung Pyo Hong, MD, of the Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, in his trial which included 19 subjects who had developed persistent dry cough while receiving ACE inhibi......s noticed that flavonol production depended on the enzyme chalcone isomerase (CHI). By inserting a Petunia gene that encodes for CHI, they engineered tomatoes with skin that had up to a 78-fold increase in flavonol levels - around the same amount as onions. The researchers found that four subsequent genera......extracts to mice and measuring creatine kinase, an enzyme produced during muscle breakdown, in the blood.// The study "raises as many questions as answers, at least in my mind," said Dr. Denis Benjamin, chair of the North American Mycological Association's toxicology committee.There are other mushrooms wh......omosome 15, called CYP19, codes for aromatase - an enzyme that converts testosterone into oestrogen in both sexes. Oestrogen influences height because it is responsible for bones fusing over at the ends, which stops people growing. A person's height depends on both genetic and environmental influences. Pr...Therapy for stopping the spread of cancer cells
An enzyme that affects the spread of cancer cells could prov...rs at the University of Georgia have found that an enzyme that affects cell surface carbohydrates is more highly expressed in cancer cells. The enzyme makes i......heart attacks than non-smokers. Paraoxonase is a enzyme which helps to prevent fatty deposits building up and blocking the blood vessels. A team of Swiss researchers examined 367 people with heart disease. Blood tests revealed significantly reduced levels of paraoxonase activity among current smokers and ...The angiotensin-converting enzyme (ACE) inhibitor ramipril, used for the treatment of hypertension, can retrieve, and may even prevent, left ventricular hypertrophy (LVH), thereby lowering the risk of stroke and myocardial infarction (MI), a new study has shown.Results from the landm...Antioxidants used for longevity
A natural antioxdant enzyme called superoxide dismutase (SOD) lacking in mice ...and how to repair it.// This natural antioxidant enzyme called superoxide dismutase (SOD) in mice normally swipe off the free radicals produced by mitochond...FDA Approves New Arthritis Drug, Bextra
...n as COX-2 inhibitors, which work by blocking// an enzyme called cyclooxygenase 2. These drugs are believed to sidestep the stomach-irritating effects of other nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin. The drug would also be indicated for treating rheumatoid arthritis and menstrual p...Enzyme may be target for obesity drugs
An enzyme involved in hormone production may help explain wh... glucocorticoids. Alteration in the levels of this enzyme in mice produces not only obesity, but obesity especially of abdominal fat. Since this enzyme is k...Ibuprofen weakens aspirin's effect
...e that ibuprofen clogs a channel inside a clotting enzyme known as cyclooxygenase-1. Aspirin gets stuck and cannot reach its own active site inside the enzyme. The study found no conflict between aspirin and three other arthritis drugs: rofecoxib, diclofenac, and acetaminophen, which is in Tylenol. But th...Choose the correct hypertensive drug
...rt failure. For instance, angiotension converting enzyme (ACE) inhibitors are more effective than other drugs in reducing the risk of heart attack. And the long-acting calcium channel blockers are linked to a 20 per cent higher risk of heart attack and heart failure in comparison with other drugs. When a n...Weight-Loss Drinks Can Make You Gassy
...ividual lacks a sufficient supply of an intestinal enzyme critical for the digestion of milk-based foods. Consuming large amounts of lactose can cause such individuals to experience bloating, diarrhoea and flatulence. While eating solid foods with milk can reduce such reactions, the researchers point out ......deoxycyclic acid, which reduced the activity of an enzyme called diamine oxidase (DAO). DAO is thought to re...ver in the bowel lining and reduced levels of this enzyme could be responsible for abnormal cell turnover. But the Oxford researchers found the olive oil se......ckly. The gel works by inhibiting the action of an enzyme involved in cell division. By applying GW8510 directly to the scalp, the drug does not enter the bloodstream and affects only the hair cells and not the cancer cells.......ibodies to glutamic acid decarboxylase (GAD65), an enzyme involved in the production of a movement-regulating neurotransmitter.// Patients are usually treated with Valium (diazepam), which is only mildly successful at controlling symptoms. While the cause of stiff-person syndrome is unknown, doctors had sus...