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Tag: "engineered" at medical news

Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis

... undesirable effects. This consists of introducing engineered genes based on the culprit peptides into the body. When the patient's immune system sees these genes as outside invaders, it produces its own neutralizing antibodies capable of restraining the disease. Essentially, the process involves teaching the i...

Endangered species may be successfully cloned in another animal's womb

...major breakthrough a Massachusetts scientists who engineered the feat has managed to clone cells from an endangered animal (Asian Gaur) and successfully impregnated an Iowa cow with the clone. The scientific journal Cloning has reported in its upcoming edition that the Iowa cow is expected to deliver the cl...

WORM! WORM! all the way

... day scientists would create organisms genetically engineered to produce vaccines and drugs to treat IBD and other diseases. Weinstock said even genetically engineered helminths are a possibility. But doctors face at least two potential hurdles before probiotics with...

New FDA Approved Drug NATRECOR For Heart Failure Patients

The US government has approved a genetically engineered drug called NATRECOR to ease the breathing of hosp... known chemically as nesiritide, is a biologically engineered version of a natural hormone that helps dilate blood vessels. That dilation helps blood flow from th...

Tomatoes for the heart

...nserting a Petunia gene that encodes for CHI, they engineered tomatoes with skin that had up to a 78-fold increase in flavonol levels - around the same amount as onions. The researchers found that four subsequent generations of the tomatoes inherited the higher level of flavonol and that 65 per cent of the com...

Drugs disrupt formation of blood vessels

...n tumours. Mice used in the study were genetically engineered to produce a form of cancer of the pancreas. The scientists tested drugs to see if they could stop the signals that are emitted to trigger the formation of the blood vessels that fuel the growth of tumours. Four compounds, known as AGM-1470, BB-94,...

UV Radiation induces Melanoma

...land exposed mice, whose skin had been genetically engineered to mimic human skin, to high doses of ultraviolet (UV) rays. The results showed that young mice went on to develop melanoma - the most serious form of skin cancer - in adulthood. A single dose of UV radiation was enough to induce melanoma in the yo...

Alcohol within the body

...Diehl's team tested the theory on mice genetically engineered to be obese. The mice were fed on a diet that did not contain alcohol, and breath samples were taken as they aged. Obesity-related fatty liver disorder usually develops in older animals and people. The scientists found that older obese mice produced ...

Nose plug-switch that stops smelling

...ls from these odour receptors cells in genitically engineered mice, one research team showed that mice lacking CNGA4 could sense odours but could not adapt to them.Other scientists studied the molecule’s behaviour in laboratory-grown cells and reported that CNGA4 speeds up the ‘nose’s closing. Without CNGA4, th...

Heriditary dental disorders

...r. Ashok Kulkarni and his colleagues genetically// engineered mice that make extra amounts of TGF-b1 (transforming growth factor beta-1) in their teeth. The animals were born with no apparent defects, but at two weeks their teeth became discolored and eventually fractured, leaving behind small stumps. Specializ...

WBC linked with periodontitis

... showed that at six weeks of age the// genetically engineered mice had lost 27 percent of their alveolar bone whereas the normal mice had no bone loss. The loss of alveolar bone, which anchors teeth in place, is an indication of periodontitis. The scientists also supplied evidence that bacteria are necessary ...

Nose plug: switch that stops smelling

...ls from these odour receptors cells in genitically engineered mice, one research team showed that mice lacking CNGA4 could sense odours but could not adapt to them. Other scientists studied the molecule’s behaviour in laboratory-grown cells and reported that CNGA4 speeds up the ‘nose’s closing. Without CNGA4,...

Surgery-Rigged pulley helps patients

...his grow-your-own-new-bone method with genetically engineered drugs to make that bone grow faster. Surgeons have long lengthened leg bones by breaking them, pulling them apart and letting the body grow new bone - just as it would if you'd naturally broken your leg. Several years ago, a New York physician adapt...

Leptin linked to Blood Clots

...t a group of overweight mice that were genetically engineered to lack the gene needed to produce leptin. He found they took an average of 70 minutes to clot, almost twice as long as normal mice who clotted at 40 minutes. Blood clotting capabilities were tested on another group of mice missing the gene for the ...

Enzyme stimulates growth of adult stem cells

...ance of MMP9 when they examined mice that had been engineered to grow and develop without the enzyme. When the researchers treated the mice with chemotherapy that severely damaged bone marrow, 72% died, while all of the mice that still produced MMP9 survived because they successfully regenerated blood and immun...

Ginseng aids Diabetes

...t on diabetic symptoms. Mice that were genetically engineered to have type 2 diabetes received injections of the substance daily for 10 days. They were then compared to mice that didn't receive the injections. Researchers found the mice that received the injections had significantly improved results on standar...

Stem cells aid to cure brain cancer

...ack and destroy brain tumour cells. The scientists engineered the cells to produce interleukin-12, a natural compound which can kill glioma cells. In this study, the stem cells were injected into mice with brain tumours. The animals survived far longer than mice not given the cells and, what is more, they also ...

Bioengineering production strains - Microbia develops new methods

...se arrays for transcriptional profiling of strains engineered to produce varying levels of lovastatin-a drug used widely to treat high cholesterol. By integrating transcriptional and metabolite data, the authors elucidated the key genetic components and critical regulatory nodes affecting lovastatin production....

Resistant tumors could be treated with the discovery of a new molecule within cancer cells

...nd in many other kinds of cancer. They genetically engineered cervical cancer cells with the gene for AURORA-A i...at when treated with Taxol only about half as many engineered cells were killed by the drug as non-engineered cells. In normal cell division, a cell can only div...

Vitamin D May Aid Breast Cancer Treatment

...d -- in this case vitamin D -- that is genetically engineered by adding or removing certain chemical elements. In the instance of EB1089, it was necessary to modify vitamin D because "at the dose you need to give to have an effect on cancer, it could cause some side effects," Sundaram says. Those side effects w...

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