How Plague-Causing Bacteria Disarm Host Defense
... they knock down the front door of resistance and disarm the cells alarm system. Now, researchers at the University of California, San Diego (UCSD) School of Medicine have identified a novel molecular target for an effector protein called YpkA, one of several effectors of the bacteria Yersinia the patho......neration of antibiotics will include products that disarm bacteria by neutralizing their virulence factors. In that way, the pathogens may be rendered harmless, without such a strong stimulus for resistance.” “By linking Scripps’s marine drug discovery program with the expertise in the Schools of Medicine......e agents called dendritic cells. Once the bacteria disarm the dendritic cells, they can evade the immune system's other defenders and spread unchecked.......s elusive bacterium."We can now figure out ways to disarm its defences through vaccines, identify it quickly through new diagnostic tests and eliminate it with specific, targeted antibiotics."...