A new century of Alzheimer's disease research
...ls, destroying the pathways along which packets of chemical “information” move. Memories cannot be stored or r...ases that may stop tau from initially changing its chemical shape. One design for a therapeutic drug could be to inhibit the molecules involved in the abnormal ...Structure of TB Enzyme Points the Way to New Drugs: Study
... So Pieters and colleagues decided to examine the chemical structure of the PknG molecule and the compound that inhibits it in atomic resolution, using a technique called X-ray crystallography. They found that the compound acted on a segment of the protein that is unique to PknG -- not shared by any of the...Blood Protein may Hold Key to Why Healthy People Get Heart Attacks
...educes the availability of nitric oxide, a natural chemical that relaxes the blood vessels. "MPO levels help to identify individuals at increased risk for CAD when traditional risk screening fails," Dr. Boekholdt said. The findings of the study were published in the July issue of the Journal of the Ameri...Chemical Injections for Fat Removal
...cal Center have been able to use simple, non-toxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals. They say the discovery, published online in Nature Medicine on July 1, could revolutionize human cosmetic and reconstructive plastic surgery and treatment of d...Gene Variation Increases the Risk of Lung Cancer
...ngels, the IL1B protein is an integral part of the chemical cascade by which cell signals moderate the response to inflammation. Variations in the gene may lead to greater expression of the protein, which is more likely to turn on the cascade and sustain the damaging effects of inflammation. Over time, the co...Variation in Genes Related to Inflammation Increase Lung Cancer Risk
... that the IL1B protein was an integral part of the chemical cascade by which cell signals moderate the response to inflammation. Variations in the gene might lead to greater expression of the protein, which is more likely to turn on the cascade and sustain the damaging effects of inflammation. Over time, th...Lab Tests Throw Up New Path for Parkinson's
...e degeneration of cells that produce the key brain chemical dopamine and can even help damaged cells to recover. Tested on lab rodents engineered to have Parkinson's, CDNF "was at least as efficient" as GDNF (glial cell-derived neurotrophic factor), which until now has generated the most excitement in this ...Scientists Discover Key to Manipulating Fat
...ity Medical Center have been able to use non-toxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals. They say the discovery, published online in Nature Medicine on July 1, could revolutionize human cosmetic surgery and treatment of diseases associated with human...When CIAs Poisoned Capsule for Castro Stuck to the Freezer!
...by the CIA to discredit Castro was a plan to place chemical powders on his boots that would cause his beard to fall out when he was in New York to speak at the United Nations in 1960. When that failed, the CIA planned to slip him a box of cigars tainted with LSD so that he would burst into fits of laughter ...Nanospectrometer Aids in Identifying Nutrient Cycle
...Laboratory can image and measure minute amounts of chemical elements. Douglas Capone and Kenneth Nealson, US...he technology produces time-series observations of chemical composition, and doubles as an electron microscope to allow researchers to overlay chemical and phys...Novel Light Weight Polymers Made Up of Carbon Nanotubes
...rther. Guptas team then added a foaming agent a chemical that creates air pockets to the material. The results astounded even the researchers; this extra step reduced the weight of the material by 50 percent and increased its flexibility. Gupta's team included U.Va. postdoctoral fellow Dr. Y. Yang, and ...Discourage Less Educated Women from Conceiving , Says New Zealand Academic
... antidote," he said. "You could of course have a chemical in the water supply and have to take an antidote. If you had contraception made easier by progress, then every child is a wanted child." Free bottled water containing contraceptives could be provided at supermarkets. Or the government could adopt S...Liver Cancer More Prevalent in Males
...nder disparity in HCC, the UCSD researchers used a chemical carcinogen, DEN, to induce cancer in mice. This resulted in HCC in 100 percent of male mice, but only in 10 to 20 percent of their female littermates. The researchers discovered that normal female mice given DEN produced far less IL-6 than the male...Neurotransmitter That can Yield New Insights in the Fight Against Diabetes Identified
...niversity of Southern California have identified a chemical that can carry the electrical signal that alerts t...repinephrine. According to the researchers, the chemical travels from the hindbrain, which receives warnings of low glucose levels from the body, to the para...Eastern Equine Encephalitis Spreading Its Tentacles in Massachusetts
...ave protested the pesticide spraying -- saying the chemical could wreak havoc on aquatic ecosystems and taint organic farms -- state officials have argued that it's worth it to protect residents from the EEE virus, which has killed six people in Massachusetts over the past three years. "I'm still not one-te...Invisible Gases Form Most Organic Haze in Urban, Rural Areas: Study
...enez said. Reactive gases are a diverse group of chemical compounds that include VOCs, surface ozone, nitrogen compounds and sulfur dioxide. All play a major role in the chemistry of the atmosphere and as such are heavily involved in inter-relations between atmospheric chemistry and climate. According to ...Smoking Linked to Lower Parkinson's Disease Risk
...al studies have indicated two possible mechanisms: chemical or biochemical processes may exist by which substances contained in cigarette smoke such as nicotine or carbon monoxide exert a protective effect and promote survival of dopaminergic neurons; or cigarette smoke alters the activity of metabolic enzyme...Completely Neutral Evolutionary Changes Helped Shape Our Genome
... of DNA containing the same repetitive sequence of chemical base pairs several hundred times. "For a long time, the basic belief of evolution was that all random genetic changes that manage to stick around have some selective advantage. But our work adds to the case that frequently, we are what we are large...Spain Withdraws Contaminated Chinese Toothpaste
... other American countries. Reportedly, a Chinese chemical maker had sold the industrial-grade chemical as glycerine, which is often used as a moistener or sweetener in products like toothpastes, soaps an......en with prostate cancer that has spread, is to use chemical suppressants or surgery to inhibit testicular synthesis of male hormones. However, this treatment does not block the production of male hormones elsewhere in the body. Abiraterone, a drug that is taken orally, inhibits an enzyme called CYP450c17, w...