Deafness and seizures result when mysterious protein deleted in mice
... perception, learning and memory.
The missing protein is a particular vesicular
neurotransmitter transporter, a machine within nerve cells that ferries ... of behavior.
Scientists have known for several years about two vesicular
glutamate transporters, VGLUT1 and VGLUT2. As would be predicted, they are ...
Virus evolution topic of Darwin talk at UH April 2
... pathogens evolve.
Turner often performs basic research on non-dangerous viruses that serve as models for important pathogens. An example is the vesicular
stomatitis virus that does not cause disease in humans but provides an excellent model for the sometimes deadly Dengue virus and other viruses ...
Neurocrine Biosciences Reports Fourth Quarter and Year-End 2008 Results
... studies. The favorable results of these studies should allow urocortin 2 to be infused for periods up to two weeks in duration in humans.
Monoamine Transporter 2 Inhibitor (VMAT2 )
VMAT2 is a protein concentrated in the human brain that is essential for the transmission of ...
Zebrafish Journal Publishes Skin Pigmentation Studies That Shed Light on the Evolution of Race
... of the guppy, the link between pigment and fish behavior, and pigment dilution mutants in fish models connected to lysosome-related organelles and vesicular
Zebrafish is an authoritative peer-reviewed journal published quarterly in print and online. This is the only peer-reviewed ...
Tumor-killing virus selectively targets diseased brain cells
... cells they target, conducted by senior author Anthony van den Pol, PhD, and his team at Yale University School of Medicine. They set out to test the vesicular
stomatis virus, which was selected for its ability to attack brain tumors and leave healthy tissue largely uninfected.
Tumor cells from brain ...
Researchers train the immune system to deliver virus that destroys cancer in lab models
The study appeared in the Dec. 9 online issue of Nature Medicine.
The technology combines infection-fighting T-cells with the vesicular
stomatitis virus that targets and destroys cancer cells while leaving normal cells unharmed. The study, which has not yet been replicated in humans, ...
Protein-dependent 'switch' regulates intracellular trafficking in epithelial cells
... sickness not only of cells but of the organ of which those cells are a part," Dr. Kreitzer explains.
Scientists have spent decades investigating vesicular
trafficking. But the exact role for each of the 41 members of the kinesin family has remained unclear.
In their study, Dr. Kreitzer's team focused ...
Study Revises Dynamin's Role in Nerve Cell Function
... recycling process,' Dr. Ryan explains. 'Essentially, the enzyme undergoes a chemical change whereby it physically squeezes off a piece of the old vesicular
membrane creating a brand new vesicle poised to take on a new load of neurotransmitter.'
Based on this work in fruit flies, neuroscientists ...
FMD tests at abattoir
... to the Institute for Animal Health.”
Ms Reynolds said today: “Further negative laboratory test results for foot and mouth disease and swine vesicular
disease mean that restrictions have been lifted on the slaughterhouse and the farm the pigs originated from.”