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Vector in Medical News

Developing gene therapy to fight blindness

... plan to deliver the MERTK gene in a viral vector a carrier commonly used to deliver genetic ... in proof-of-concept studies that viral vector delivery of MERTK corrects the mutant gene and ... as early as spring of 2010. The same type of vector has been successfully tested in both animals and ...

Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

... . They present a novel adenoviral vector that binds to the EphA2 receptor (EphA2R). This ... viral capsid. The ablated retargeted adenoviral vector was produced on 293T cells. Specific targeting of this novel adenoviral vector to pancreatic cancer was investigated on ...

Coming Soon: Lung-Cancer Spray?

... cancer that were treated with a vaporized viral vector twice a week for four weeks had fewer, smaller ... In the study, researchers used a lentiviral vector derived from a retrovirus able to infect ... causing lasting genetic changes. The lentiviral vector included a carboxyl-terminal modulator protein ...

Vaporized viral vector shows promise in anti-cancer gene therapy

... lung cancer therapy employing a vaporized viral vector to deliver a cancer-inhibiting molecule directly ... genetic changes. They transfected the lentiviral vector with a negative regulator of Akt signaling, ... to the aerosolized CTMP vector, one-third to the vector alone and one third were untreated. "In this ...

Veterans Administration Awards Small Business' $13 Million Contract to Digitize Veterans Health Records

... Department of Veterans Affairs has selected DOMA vector and DOMA Technologies to provide Record ... Department of Veterans Affairs has selected DOMA vector and DOMA Technologies to provide Record ... and participates in the SBA 8(a) program. DOMA vector is a Protégée of DOMA Technologies. ...

Nose-spray vaccine against botulism effective in first tests

... inoculation (nose spray) of the adenovirus vector brought about a high level of HC50-specific ... symptoms, whereas none of the mice that received vector control without Hc50 survived. The protective ... intranasal vaccination of an adenovirus-based vector encoding a humanized HC 50 of BoNT/C can provide ...

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Vector in Medical Technology

Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting

... license to utilize Adeno-Associated Viral (AAV) vector technology in heart failure, which bodes well for ... is a recombinant adeno-associated viral (rAAV) vector that transfers the SERCA2a gene into heart muscle ... low levels of pre-existing antibodies to the AAV vector did not show improvement in these parameters. The ...

AlphaVax Announces Promising Results in Melanoma Studies

... the ability of AlphaVax's virus-like replicon vector particles (VRP) encoding melanoma-specific tumor ... intervention with a novel vaccine vector such as ours may prove beneficial as a treatment ... company that uses a novel alphavirus vector platform technology that has proven to be highly ...

VIRxSYS to Host a Web Conference to Announce Clinical Trial Update

... removed. VIRxSYS used this vector to deliver RNA antisense targeting the HIV ... a new vaccine approach that uses a lentiviral vector expressing HIV antigens. In the study, VRX1023 ... gene therapies because it uses a lentiviral vector derived from HIV-1 itself. Unlike other viral ...

Gene Therapy Improves Vision in Patients with Congenital Retinal Disease

... better functioning eye. The LCA gene therapy vector showed no signs of causing inflammation in the ... biological effects of the therapeutic gene or the vector used to carry it. The patients enrolled in ... a period of six months following the gene therapy vector administration. One patient was better able to ...

In Blood Vessel Stents, Innovative Materials Allow Better Control, Delivery of Gene Therapy

... is an amplifier that increases the dose of gene vector more than fourfold over the previous ... component, the stent can be tuned to release vector at a controlled rate that can theoretically be ... studies have shown that 90 percent of the gene vector is released within 12 to 24 hours, after which ...

VIRxSYS Presents Data on HIV Vaccine at Keystone HIV Vaccine Symposia

... HIV-Based Lentiviral vector VRX1023 Shows Promising Results GAITHERSBURG, ... approach -- using HIV-based lentivector as vector boost. VRX1023, an HIV antigen expressing ... is using an engineered HIV-based lentiviral vector to deliver the vaccinating antigens. In small ...

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Vector in Medical Products

Vector Volume Application

Description:... The vector Volume Application for POLYGRAM NET™ (PNET) works with the ... may be carried out manually with the help of a metronome feature in the vector Volume Application. The analysis requires the use of a manometry catheter ...
Company:Medtronic Gastroenterology

Multi-Use Pediatric Anorectal Water Perfused Catheters

Description:... We have water perfused manometric catheters for esophageal, anorectal and vector volume diagnostic tests. All Medtronic Water Perfused Catheters are made using clear, medical grade PVC tubing. For pressure measurement in the ...
Company:Medtronic Gastroenterology

Multi-Use Pediatric Esophageal Water Perfused Catheters

Description:... We have water perfused manometric catheters for esophageal, anorectal and vector volume diagnostic tests. All Medtronic Water Perfused Catheters are made using clear, medical grade PVC tubing. For pressure measurement in the ...
Company:Medtronic Gastroenterology

Multi-Use Adult Anorectal Water Perfused Catheters

Description:... We have water perfused manometric catheters for esophageal, anorectal and vector volume diagnostic tests. All Medtronic Water Perfused Catheters are made using clear, medical grade PVC tubing. For pressure measurement in the ...
Company:Medtronic Gastroenterology

Single-use Anorectal Water Perfused Catheters

Description:... because cleaning is eliminated, you have more time for patient care. We have water perfused manometric catheters for esophageal, anorectal and vector volume diagnostic tests. All Medtronic Water Perfused Catheters are made using clear, medical grade PVC tubing. For pressure measurement in the ...
Company:Medtronic Gastroenterology

Multi-Use Adult Esophageal Water Perfused Catheters

Description:... We have water perfused manometric catheters for esophageal, anorectal and vector volume diagnostic tests. All Medtronic Water Perfused Catheters are made using clear, medical grade PVC tubing. For pressure measurement in the ...
Company:Medtronic Gastroenterology

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Vector in Medical Definition

Ramón Carrillo

... 1946 to 132.000 in 1954. He eradicated, in only two years, endemic diseases such as malaria , by means of highly aggressive campaigns against the vector . Syphilis and veneral diseases practically vanished. He built 234 free, public hospitals or policlinics, lowered tuberculosis ' mortality rate ...
Vector in Medical Dictionary

Adenoviruses

... of these virus es. Other virus es used as vector s include adenoviruses , adeno-associated virus ... , and eye infections . Other viral vector s, like the adenoviruses , are often recognized ... so it performs its role properly after vector delivery is difficult. ...

Adenovirus

... military recruits. Other virus es used as vector s include adenovirus es , adeno-associated ... , Pox virus , and Myxo virus . Other viral vector s, like the adenovirus es , are often ... so it performs its role properly after vector delivery is difficult. types of pneumonia ...

Vector

... vector -borne disease s are infections transmitted by ... many others in every country in the world. vector : A nonpathogenic bacterium or virus used to ... to child during pregnancy or birth . vector An animal that spreads an infectious agent from ...

Carrier

... age 60 years ... Globally, ticks are second only to mosquitoes as vector s ( carrier s) of human disease . In North America, ticks outrank even mosquitoes as the leading perpetrator of vector -borne infections . Hepatitis C : Are You a Silent Carrier ? Health ...

Retrovirus

... retrovirus es to de liver the desired gene . Other virus es used as vector s include adenoviruses , adeno-associated virus es, lentiviruses, ... Med Help International ] [ Search ] [ Ask the Doctor Forums ] ... Some vector s, like retrovirus es, can also enter cells functioning properly and ...

Ticks

... about one in 250. Globally, ticks are second only to mosquitoes as vector s ( carrier s) of human disease . In North America, ticks outrank even mosquitoes as the leading perpetrator of vector -borne infections . Both deer ticks and black-legged ticks are ...

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Vector in Biological News

Amarna Therapeutics B.V. and TNO announce SVac research and development partnership

... a revolutionary novel viral gene delivery vector platform technology SVac for producing human ... the extremely important therapeutic area of viral vector and gene delivery technologies and is yet another ... therapeutics is the SVac viral gene delivery vector platform, which provides sensational characters ...

IVCC and Syngenta start project for novel insecticidal active ingredient for malaria control

... has increased significantly its activities in the vector Control area since 2008. We are really excited ... project with IVCC," said Frdric Baur, Global Head vector Control at Syngenta. "It represents a key ... project will accelerate the development of new vector control products, which benefit communities where ...

UF researchers develop improved gene therapy agent

... and doctors using AAV as a gene therapy vector how to administer enough of the gene-toting ... was working 29 times better than the standard vector was at incorporating the new gene into cells, at ... goal of creating what Srivastava calls a perfect vector that lacks all seven phosphate-attracting ...

U. Mass Medical School and Carnegie announce licensing agreements with Oxford BioMedica

... using lentiviral vectors. A lentiviral vector is based on a type of virus that infects dividing ... opportunities presented by Oxfords lentiviral vector delivery technology is intriguing to us. We have ... on their established broad IP in the lentiviral vector delivery space. Our hope is to see the further ...

UMMS and CIW grant key RNAi rights to Oxford Biomedica

... using lentiviral vectors. A lentiviral vector is based on a type of virus that infects dividing ... opportunities presented by Oxfords lentiviral vector delivery technology is intriguing to us. We have ... on their established broad IP in the lentiviral vector delivery space. Our hope is to see the further ...

New screening strategy for detection of chagas disease in children

... interrupting the transmission of T. cruzi through vector control measures (such as insecticide spraying), ... a peri-urban community of Arequipa, Peru, where a vector control campaign is currently disrupting ... to data that had been collected during the vector control campaign (entomological, spatial, and ...

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Vector in Biological Technology

Cynvec to Present at The 2009 New York Venture Summit

... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly ... Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real ... CYN 101 in the third quarter of 2009. The sindbis vector has demonstrated in vivo efficacy delivering a ...

Cynvec to Present at the 11th Annual Shanghai International Forum on Biotechnology and Pharmaceutical Industry

... titled "Cynvec: Breakthrough Oncolytic Viral vector Therapy with Sindbis" at the 11th Annual Shanghai ... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly ... Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real ...

Cynvec to Present at New York Biotechnology Association 18th Annual Meeting

... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly ... Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real ... cancer in the third quarter of 2009. The sindbis vector has also demonstrated in vivo efficacy delivering ...

Cynvec to Present at the BIO National Venture Conference

... CYN 101 is a replication defective, apoptotic RNA vector that has shown tumor eradication and highly ... Cynvec is also developing a companion vector that will provide an in vivo, quantitative, real ... cancer in the third quarter of 2009. The sindbis vector has also demonstrated in vivo efficacy delivering ...

GeneCopoeia Introduces Genome-Wide MicroRNA (miRNA) Functional Analysis Tools

... reagents and tools. They include 1) miExpress(TM) vector based precursor miRNA expression clones; 2) ... RT-qPCR system. Constructed in a lentiviral vector system, miExpress(TM) precursor miRNA expression ... mouse (450), and rat (270). These lentiviral vector based expression constructs allow efficient ...

Virginia Tech researchers discover how mosquitoes avoid succumbing to viruses they transmit

... small RNAs modulate pathogenesis in disease vector mosquitoes," by Myles; Michael R. Wiley of ... a mosquito called Aedes aegypti, an important vector of yellow fever and dengue. In response, the ... a virus that is transmitted by an arthropod vector , said Myles. The researchers used an Illumina ...

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Vector in Biological Products

Zero Background Cloning Kit from Invitrogen

Description:... Zero Background Cloning Kit includes the pZErO-1 vector with Zeocin resistance for selection in E. coli. The pZErO-1 vector utilizes positive selection to eliminate high ... of the Zeocin resistance gene reduces the overall vector size for increased ligation and transformation ...
Company:Invitrogen

PinPoint™ Vector Sequencing Primer from Promega

Description:... The PinPoint™ vector Sequencing Primer is designed for sequencing ... Xa Vectors. The sequence of the PinPoint™ vector Sequencing Primer is 5-CGTGACGCGGTGCAGGGCG-3. It ... Features: Performance Tested: The PinPoint™ vector Sequencing Primer is tested in double-stranded ...
Company:Promega

Zero Blunt TOPO Kit for Sequencing with One Shot Mach1 T1 Phage-Resistant Chemically Competent E. coli from Invitrogen

Description:... insertion site. This minimizes the amount of vector DNA that needs to be read before reaching the ... your insert.vectors are available. The pCR4-TOPO vector provides 3-T overhangs for direct ligation of Taq-amplified PCR products. The pCR4Blunt-TOPO vector provides blunt ends for cloning PCR products ...
Company:Invitrogen

pAcAB4 Baculovirus Transfer Vector from BD Biosciences Pharmingen

Description:... The pAcAB4 vector is a 10.0 kb Autographa californica (AcNPV) polyhedrin locus-based vector that contains two copies of the AcNPV polyhedrin ... site downstream of the first p10 promoter. This vector allows simultaneous expression of four foreign ...
Company:BD Biosciences Pharmingen

Ligase, T4 DNA from USB Corp.

Description:... of ligation reaction, a combination of 2040 ng of vector DNA and a 1:3-10 fold molar excess of foreign DNA ... most cloning purposes. 1. Combine the following: vector DNA (2040 ng) __ l Insert DNA (310-fold molar ... be carried out at a higher concentration of both vector and insert DNA. To stimulate the blunt-end ...
Company:USB Corp.

LabShare 3.0 for Vector NTI Data Management Software from Invitrogen

Description:... LabShare for vector NTI allows you to store and manage very large ... desktop sequence analysis applications vector NTI Advance on Windows PCs and vector NTI Suite on Macs running OS X. By combining ...
Company:Invitrogen

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Vector in Biological Definition

Gradient

... In vector calculus , the gradient of a scalar field is a vector field which points in the direction of the ... is noted by: where ( nabla ) is the vector differential operator del , and φ is a ...

Operator

... most frequently met usage is a mapping between vector spaces ; this kind of operator is distinguished by taking one vector and returning another. For example, consider an ... 3.4 Fundamental operators on scalar and vector fields 4 Operators in physics 5 See ...

Malaria

... parasite , Plasmodium (one of the Apicomplexa ) and the transmission vector for human malarial parasite is the Anopheles mosquito . For his ... and Training in Tropical Diseases story of the discovery of the vector of the malarial parasite History of discoveries in malaria New ...

Polymerase chain reaction

... PCR is often used to amplify the gene, which can then be inserted into a vector (a vector is a piece of DNA which 'carries' the gene into the GEO) such as a ...

Biotechnology

... See also Biochemistry Bioreactor Biorobotics EU Directive on the patentability of biotechnological inventions Expression vector Genetic engineering genetically modified food Industrial biotechnology intein List of publications in biology#biotechnology ...

Biomechanics

... mechanisms and structures can be simulated and studied. Relevant mathematical tools include linear algebra , differential equations , vector and tensor calculus , and computational techniques such as the finite element method. The study of biomaterials is of crucial importance to ...

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Vector in Biological Dictionary

Vector

... vector graphics is the use of geometrical primitives ... mathematics, physics, and engineering, a vector is a geometric object that has both a magnitude (or length), direction and sense, . A vector is frequently represented by a line segment ...

Vectors

... have close analogues for vectors . ... A vector space is a mathematical structure formed by a ... of two force vectors : ... Examples of vector quantities which have been previously discussed ... things happening in space by giving a ... vector n. Mathematics. A quantity, such as velocity, ...

Subcloning

... a particular gene of interest from a parent vector to a destination vector in order to further study its functionality. ... and subcloning . General definition. Cloning vector - intentionally designed artificial DNA construct ...

Shuttle vector

... A shuttle vector is a vector constructed so that it can propagate in two ... . Therefore, DNA inserted into a shuttle vector can be tested or manipulated in two different ...

Shotgun cloning

... by DNA sequencing from both ends of the vector is ... This involves shotgun cloning the ... siRNA (Gene Silencing) Two-Hybrid. Other. vector Construction ... Shotgun , cloning ... cloning into a pSMART® or other Lucigen vector ... GapFree cloning uses Lucigen's ...

Recombinant clones

... clones in the library containing the intact vector were ... Non- recombinant clones contain the ... ... Clones are constructed by ligation of a vector and a fragment insert. ... Home / Windows / ... Recombinant DNA Technology ... its cloning vector in the lab, it is called a " recombinant DNA ......

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