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Uric in Medical News

The Gout & Uric Acid Education Society (GUAES) Announces New Survey Results Highlighting Major Gaps in Public Awareness of Gout

... NEW YORK, May 22 /PRNewswire/ -- The Gout & uric Acid Education Society announced today that new ... Edwards, M.D., chairman of the Gout & uric Acid Education Society, and a specialist in ... is associated with an abnormally high level of uric acid in the blood (a condition known as ...

Arthritis Trial Leads to Potential Cure for High Blood Pressure

... the patients in the trial have recorded reduced uric acid levels after being in the program for as ... Dr. Palma noticed a marked drop in uric acids levels in all patients, up to 50% in some ... of the product for arthritis, as well as the uric acid discovery, was recently aired on Australias ...

FDA approves ULORIC (febuxostat) for the chronic management of hyperuricemia in patients with gout

... gout a new treatment option that helps prevent uric acid production," said Nancy Joseph-Ridge, M.D., ... gout is the reduction and maintenance of serum uric acid levels of less than 6 mg/dL. ULORIC, a ... inhibitor, effectively lowers levels of serum uric acid in patients with hyperuricemia associated ...

C8 Science Panel Completes Uric Acid Study

... The C8 Science Panel has completed a new study on uric acid and C8 and C8S, based on existing data from the C8 Health Project. While increased uric acid is associated with higher levels of C8 and ... that these chemicals can cause an increase in uric acid. The Science Panel team recently ...

Gene Mutation in Dalmatians Sheds Light on Kidney Stones in Humans

... Finding explained high levels of uric acid in dog breed FRIDAY, Nov. 7 ... -- A gene mutation that causes the high levels of uric acid that lead to bladder stones in Dalmatians ... apes and Dalmatians produce elevated levels of uric acid in their urine and blood. Other dog breeds ...

New Drug Helps Relieve Gout

... Pegloticase normalized uric acid levels within 6 hours for participants in ... gout drug called pegloticase lowered levels of uric acid in the blood to target levels within a few ... takes about two hours. Pegloticase normalized uric acid levels within six hours for participants in ...

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Uric in Medical Technology

Phase III Trial Results Show Elitek(R) (rasburicase) Significantly Reduced Plasma Uric Acid Levels versus Allopurinol in Adults with Hematologic Cancers at Risk for Tumor Lysis Syndrome

... (rasburicase) significantly reduced plasma uric acid (PUA) levels compared to allopurinol alone ... alone, which showed a reduction in plasma uric acid levels for the sequential combination versus ... by-products into the blood system such as uric acid, faster than can be eliminated. Elevated ...

Arthritis Advisory Committee Recommends FDA Approval of Febuxostat for the Treatment of Hyperuricemia in Patients With Gout

... studied for its ability to lower levels of serum uric acid in patients with hyperuricemia associated with gout. Hyperuricemia, elevated uric acid levels in the body, is associated with gout, ... symptoms, and diarrhea. About Gout and uric Acid ...

Ardea Biosciences Advances Lead Product Candidate for the Treatment of Gout, RDEA594, Into Phase 1 Clinical Trial

... the safety, tolerability, pharmacokinetics and uric acid lowering effects of single ascending oral ... disease caused by abnormally elevated levels of uric acid in the blood stream. These abnormally elevated levels lead to the deposition of uric acid crystals in and around the connective tissue ...

Ardea Biosciences Identifies Lead Development Candidate for Gout, RDEA594

... that is caused by abnormally elevated levels of uric acid in the blood stream. RDEA594 is a major ... to be responsible for essentially all of the uric acid lowering effects seen with RDEA806. ... the URAT1 transporter-mediated uptake of uric acid ex vivo and increases uric acid excretion in ...

Ardea Biosciences, Inc. Announces New Clinical Development Program Directed Toward the Treatment of Gout

... Dose-Dependent Reduction in Serum uric Acid in Phase 1 Clinical Study - Phase 2 ... disease caused by abnormally elevated levels of uric acid in the blood stream. These abnormally elevated levels lead to the deposition of uric acid crystals in and around the connective tissue ...

Savient Provides Update on Pegloticase BLA

... can be detected within the first 4 months through monitoring serum uric acid in normal medical practice patterns. A lack of uric acid response correlates with high levels of antibody production. The ...
Uric in Medical Products

Infinity Uric Acid (Powder)

Description:... The Infinity uric Acid powder reagent once reconstituted offers the laboratory all the ... quick result turnaround time. The proprietary technology of the Infinity uric Acid powder reagent provides a long shelf life and stability once ...
Company:ThermoFisher Scientific

Infinity Uric Acid (Liquid)

Description:... The Infinity uric Acid single liquid stable reagent offers the laboratory all the ... quick result turnaround time. The proprietary technology of the Infinity uric Acid reagent provides a long shelf life that will minimize reagent ....
Company:ThermoFisher Scientific

Uric Acid (UA) Liquid

Description:... URCA (Uric acid) method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of uric acid in serum, plasma and ....
Company:Randox Laboratories Ltd.

Uric Acid (UA)

Description:... For the quantitative in vitro determination of uric Acid in serum, plasma and ...
Company:Randox Laboratories Ltd.

StatStrip Glucose Monitoring System

Description:... one well. Novas exclusive Multi-Well system measures and corrects hematocrit interference as well as interferences from acetaminophen (Tylenol), uric acid, ascorbic acid (Vitamin C), maltose, galactose, xylose, and lactose. StatStrip also eliminates oxygen interference to provide accurate glucose ...
Company:Nova Biomedical

Uric Acid (Liquid) Reagent Set

Description:... For the quantitative determination of uric acid in ....
Company:Teco Diagnostics

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Uric in Medical Dictionary

Acid

... it doesn't describe the affected body part. uric acid tests Definition uric acid tests are tests that are done to measure the levels of uric acid in blood serum or in urine . ...

Arthritis

... , gout : Joint inflammation caused by uric acid crystal deposits in the joint space. An attack is usually extremely painful. The uric acid crystals are deposited in the joint fluid ... A form of arthritis caused by deposits of uric acid crystals in the joints , usually the feet, ...

Gout

... which the body has a problem in the handling of uric acid . People with gout either produce too much uric acid or more commonly their bodies have a ... and deforming. It results from deposits of uric acid crystals in connective tissue or joints ....

Hyperuricemia

... ... Hyperuricemia Excessively high levels of uric acid in the blood , often producing gout . ... that is one of the building blocks of DNA. uric acid is produced when p urine is broken down in ... Gout is caused by too much uric acid in the blood ( hyperuricemia ). ...

Metabolism

... metabolism that results in an overproduction of uric acid or a reduced ability of the kidney to eliminate uric acid . The exact cause of the metabolic defect is ... are hyperuricosuria which is a disorder of uric acid metabolism , gout , excess intake of ...

Uric acid

... uric acid is a waste product that results from the ... (Nucleic acids are the building blocks of DNA.) uric acid is made in the liver and excreted by the kidney s. uric acid is the end product of p urine metabolism ...

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Uric in Biological News

Too much fructose could leave dieters sugar shocked

... part of the equation, UF researchers say. Eating too much fructose causes uric acid levels to spike, which can block the ability of insulin to regulate ... in the UF College of Medicine. UF researchers first detailed the role of uric acid on insulin resistance and obesity in a 2005 study in rats. ...

Experts lay to rest long-held misconceptions about high fructose corn syrup at ILSI-USDA workshop

... sugar (or sucrose) have differing effects on satiety, overall energy balance, metabolic hormones or biochemical metabolites such as triglycerides and uric acid all suggesting no unique causal role for high fructose corn syrup in obesity. According to Suzanne P. Murphy, Ph.D., R.D., research ...

Seabird ammonia emissions contribute to atmospheric acidity

... climate change on ecosystem function." According to Chief Editor Peter Brimblecombe, this study is "fascinating in the context that birds excrete uric acid unlike mammals, where excreted urea is readily converted to ammonia. Ammonia is the only major alkaline gas in the atmosphere and has a major ...

New player in commitment to life as a fat cell

... for its role in producing the metabolic byproduct uric acid, XOR had earlier been implicated in gout, ... is a painful type of arthritis that results when uric acid crystals build up in the joints. "These ... association with the catabolism of purines into uric acid, the production of reactive oxygen species, ...

Killing the messenger RNA -- But which one?

... for an essential enzyme involved in synthesizing uric acid. If levels of the enzyme are poorly ... example, too-high levels of the enzyme can cause uric acid levels to rise in the blood, triggering ... episodes of gout. Similarly, in the brain, excess uric acid can damage sensory neurons and cause ...

Simple home spit test to spot deadly pre-eclampsia

... problems with high blood pressure may not occur until the latter stages. The new test works by monitoring levels of urate, a salt of uric acid, increased levels of which are thought to be due to impaired kidney excretion in pre-eclampsia. 'A salivary urate test is simple, ...
Uric in Biological Technology

FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout

... gout a new treatment option that helps prevent uric acid production," said Nancy Joseph-Ridge, M.D., ... gout is the reduction and maintenance of serum uric acid levels of less than 6 mg/dL. ULORIC, a ... inhibitor, effectively lowers levels of serum uric acid in patients with hyperuricemia associated ...

Savient's Pegloticase Data in Treatment-Failure Gout Patients Presented at 72nd Annual Meeting of the American College of Rheumatology Conference

... endpoint relating to the normalization of plasma uric acid, for pegloticase 8 mg intravenous infusion ... treatment effect not only for the control of uric acid, but more importantly for the amelioration ... the GOUT 1 and GOUT 2 studies (Gout Outcomes and uric Acid Treatment) and the OLE Study is known as ...

Ardea Biosciences to Present Data on Gout and Inflammation Programs at the 2008 ACR/ARHP Annual Scientific Meeting

... a.m. PDT Abstract Title: RDEA594, A Potential uric Acid Lowering Agent through Inhibition of uric Acid Reuptake, Shows Better ... kidney, which is responsible for regulation of uric acid levels. We are evaluating our lead MEK ...

Ardea Biosciences' Advances RDEA806 Into Phase 2a Proof-of-Concept Study for Gout

... to be responsible for essentially all of the uric acid lowering effects seen with RDEA806. uric acid lowering effects have been observed ... In this trial, we plan to evaluate the serum uric acid (sUA) level, pharmacokinetics, safety and ...

Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology

... statistically significant reduction of serum uric acid (sUA) compared to placebo. In order to ... inhibitory effect on the URAT1-mediated uptake of uric acid ex vivo and increases uric acid excretion in animal models. These findings ...

Ardea Biosciences Establishes Scientific Advisory Board for Inflammation Program

... drug delivery. Recent areas of study include transporters in the lung, uric acid transporters, drug-induced changes in uric acid transporters, species effect on transporters and drug transports ...
Uric in Biological Products

Mouse Anti-Human Xanthine Oxidase / Aldehyde Oxidase Ab-2 Mouse Monoclonal Antibody, Biotin Conjugated, Clone 145.4 from Lab Vision

Description:... In normal tissues this enzyme exists predominantly as XDH which converts hypoxanthine and xanthine to uric acid, a critical plasma antioxidant. During ischemia, XDH is reversibly converted to the oxygen radical producing XO by oxidation of essential ...
Company:Lab Vision
Uric in Biological Definition

Purine

... enzymes , including xanthine oxidase , into uric acid . High levels of uric acid can predispose to gout when the acid ... urease enzyme that can further degrade uric acid. The deficiency of another enzyme, ...

Enzyme

... Urease : hydrolizes urea into carbon dioxide and ammonia Xanthine oxidase : oxidizes hypoxanthine to xanthine and further to uric acid Purification Since enzymes are proteins , enzyme purification begins with protein purification . Each step in the purification ...

Excretion

... , amoebae , and various parasitic worms . Urine, on the other hand, contains excess water, salt, and protein waste in the form of urea as uric acid, and seldom any pathogens; should a person be in a situation of insufficient water and in danger of overheating due to lack of persperation, ...

Osmoregulation

... and is generally converted to less toxic substances after it is produced then excreted; mammals convert ammonia to urea while birds and reptiles form uric acid to be excreted with other wastes via their cloacas. How osmoregulation is achieved in vertebrates Four processes occur: filtration ...

Protein

... substance. It is then converted in the liver into urea , a much less toxic chemical, which is excreted in urine . Some animals convert it into uric acid instead. Protein nutrition in humans In terms of human nutritional needs, proteins come in two forms: complete proteins contain all ...

Urea cycle

... than ammonia, therefore organisms which can't easily and quickly remove ammonia usually have to convert it to some other substance, like urea or uric acid . Insufficiency of the urea cycle occurs in some genetic disorders ( inborn errors of metabolism ), and in liver failure . The result in ...

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Uric in Biological Dictionary

Uric acid

... uric acid (or urate) is an organic compound of ... and hydrogen with the formula C5H4N4O3. uric acid n. A semisolid compound, C 5 H 4 N 4 O 3 ... metabolism and is the chief nitrogenous High uric acid level — Overview covers definition, ...

Purine

... Dietary purines are converted into serum uric acid (which is can cause gout when ... Purine ... bases are guanine (G) and adenine (A). uric acid, the offending substance in ... Get ... ... MODERATELY HIGH IN PURINES (100 to 400 mg. uric acid/100g) Bean, seed, white, dry ... A ...

Backcross

... cannot be AKC registered nor shown in conformation at ... Normal uric Acid Dalmatians also known as Low uric Acid Dalmatians & Backcross Dalmatians ... The "Dalmatian Backcross ...

Kidney

... KIDNEY STONES OVERVIEW Kidney stones (also called nephrolithiasis or ... The first kidney stone and asymptomatic nephrolithiasis in adults. uric acid nephrolithiasis ... ...

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