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Urea in Medical News

Hyperion Therapeutics Raises $60 Million Series C

... the chronic treatment of patients with urea cycle disorders (UCD). The capital will fund the ... unmet needs remain in the treatment of both urea cycle disorders and hepatic encephalopathy," said ... management of patients with the most prevalent urea cycle disorders: carbamylphosphate synthetase ...

Hyperion Therapeutics Announces Results of Phase I Study in Patients With Liver Cirrhosis

... management of patients with the most prevalent urea cycle disorders: carbamylphosphate synthetase ... providing a potential alternative pathway to the urea cycle for the disposal of waste nitrogen through ... for the use of HPN-100 in the treatment of urea cycle disorders and plans to initiate a phase II ...

Hyperion Therapeutics Completes Phase 2 Data Analysis and Schedules End of Phase 2 Meeting With FDA for HPN-100 in the Chronic Treatment of Urea Cycle Disorders

... current standard of care in patients with urea cycle disorders. Data from the trial will be ... to develop a new therapy for patients with urea cycle disorders," said Dr. Bruce Scharschmidt, ... Cindy LeMons, Executive Director of the National urea Cycle Disorders Foundation (NUCDF). ...

World fertilizer prices continue to soar, scientists stress need for fertilizer efficiency

... more steeply than the price of nitrogen-based urea because production sources are more limited, Roy ... material resource to provide hydrogen needed in urea production. Thats why urea plants are dispersed in oil-producing regions ...

Hyperion Therapeutics Announces Enrollment of First Patient in Phase 2 Clinical Trial in Patients With Hepatic Encephalopathy

... respectively to provide an alternative route to urea for waste nitrogen excretion and thus attenuate ... in patients with deficiencies in enzymes of the urea cycle. In acute neonatal hyperammonemic coma, ... In patients with deficiencies in enzymes of the urea cycle, the most common adverse reactions are ...

Hyperion Therapeutics Elects Lota Zoth to Board of Directors

... division currently markets two products in the United States for urea cycle disorder. The Company is also conducting two phase II trials, one in the chronic treatment of urea cycle disorder and the other in the treatment of acute hepatic ...

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Urea in Medical Technology

Hyperion Therapeutics Receives Orphan Drug Designation for HPN-100 for the Treatment of Urea Cycle Disorders

... treatment of patients with enzymes of the urea cycle. The Company recently announced results ... management of patients with the most prevalent urea cycle deficiencies including those related to ... drug designation for HPN-100 in the treatment of urea cycle disorders is an important milestone and ...

Hyperion Therapeutics Announces Results for Phase II Study in Urea Cycle Disorders

... phase II study of HPN-100 for the treatment of urea cycle disorders. The data was presented on March ... A Novel Ammonia Scavenging Agent In Adults With urea Cycle Disorders (UCDs) ." (Logo: ... the potential of HPN-100 for the treatment of urea cycle disorders." ...

Hyperion Therapeutics Completes Enrollment in Phase 1/2 Clinical Trial in Patients With Urea Cycle Disorders

... (sodium phenylbutyrate) in patients with urea cycle disorders (UCD). The company plans to ... to improve care for these patients." About urea Cycle Disorder UCDs are inherited, inborn ... in one of the key enzymes that comprise the urea cycle, the body's primary vehicle for removing ...

Hyperion Therapeutics Announces Enrollment of First Patient in Phase 1/2 Clinical Trial of GT4P in Patients With Urea Cycle Disorders

... Tri (4-Phenylbutyrate) (GT4P) in patients with urea cycle disorders (UCDs). (Logo: ... of GT4P focused on the chronic management of urea cycle disorders," said Marvin Garovoy, Senior ... in the chronic management of patients with urea cycle disorders involving deficiencies ...

Results and Additional Analyses From Study Show That Corthera's Relaxin for Acute Heart Failure is the Strongest Predictor of Improved Longer-Term Outcomes Following Hospital Discharge When Compared to Other Variables

... In the 60-day multivariate analysis, relaxin treatment was the strongest predictor of less CV death or heart failure re-admission (p<0.01). Blood urea nitrogen (BUN) on admission (p=0.02) and WHF during hospitalization (p=0.02) were also significant predictors. Relaxin treatment was the only ...

Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results

... Renal Function In studies of ACE inhibitors in patients with unilateral or bilateral renal artery stenosis, increases in serum creatinine or blood urea nitrogen (BUN) have been reported. There has been no long-term use of olmesartan medoxomil in patients with unilateral or bilateral renal artery ...
Urea in Medical Products

Infinity Urea (Nitrogen) (Powder)

Description:... The Infinity urea (Nitrogen) powder reagent once reconstituted offers the laboratory all the ... quick result turnaround time. The patented technology of the Infinity urea (Nitrogen) powder reagent provides a long shelf life and stability once ...
Company:ThermoFisher Scientific

Infinity Urea (Nitrogen) (Liquid)

Description:... The Infinity urea single liquid stable reagent offers the laboratory all the convenience of ... quick result turnaround time. The patented technology of the Infinity urea reagent provides a long shelf life that will minimize reagent ....
Company:ThermoFisher Scientific

Urea (BUN)

Description:... The BUN method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of urea nitrogen in serum, plasma and ....
Company:Randox Laboratories Ltd.

Urea (Kinetic) 1 minute read

Description:... For the quantitative in vitro determination of urea in serum, plasma and ....
Company:Randox Laboratories Ltd.

Urea (Kinetic) 3 minute read

Description:... For the quantitative in vitro determination of urea in serum, plasma or ....
Company:Randox Laboratories Ltd.

EnteroScreen 4™

Description:... aid in the detection and the differentiation of Salmonella and Shigella species. Three media, Modified Lysine Iron Agar, Lysine Iron Agar (LIA), and urea Agar, are used to screen non-lactose fermentors isolated from stool specimens. This battery of tests is helpful in differentiating Salmonella and ...
Company:Hardy Diagnostics

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Urea in Medical Definition

Pathology

... carboxylase deficiency ) - Transport ( Cystinuria , Cystinosis , Hartnup disease ) - Sulfur ( Homocystinuria , Cystathioninuria ) - urea cycle ( Argininosuccinic aciduria , Citrullinemia , Hyperammonemia ) - Glutaric acidemia type 1 - Sarcosinemia Carbohydrate ...
Urea in Medical Dictionary

BUN

... Forums ] ... BUN Definition: BUN ( blood urea nitrogen ) is a test that measures the amount of urea nitrogen (a breakdown product of protein metabolism ) in the blood . BUN ( Blood urea Nitrogen ) Test What is the BUN test? The ...

Creatinine

... levels of serum creatinine or blood urea nitrogen , which indicate decreased kidney ... body's waste products of metabolism (such as urea and creatinine ) may be found in the blood . ... blood chemicals, such as creatinine and urea nitrogen . Additional tests may be necessary to ...

Urea Cycle

... The urea cycle is a metabolic process in which waste ... Rhythms ( Arrhythmias ) Abnormality of the urea Cycle - Hereditary (Hereditary urea Cycle Abnormality) ABO Incompatibility ...

Urea nitrogen

... Blood urea nitrogen : Abbreviated BUN . A measure primarily of the urea level in blood . urea is cleared by the kidney . Disease s that ...

Uremia

... from advanced stages of kidney failure in which urea and other nitrogen-containing wastes are found in ... Uremia : The presence of excessive amounts of urea in the blood , which may be a sign of kidney ... The illness associated with the buildup of urea in the blood because the kidney s are not ...

Abnormal posturing

... Bleeding ( Vagina l Bleeding Between Periods) Abnormality of the urea Cycle - Hereditary (Hereditary urea Cycle Abnormality) ABO Blood Typing ( Blood Typing ) ... Call If: ...

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Urea in Biological News

Urea tanks on diesel trucks -- that's the law in the United States starting in 2010

... urea tanks will be standard equipment for most new ... States after Jan. 1, 2010. An automotive grade of urea will be injected into the vehicles' exhaust ... respiratory and heart diseases. The system, urea SCR or "urea-based selective catalytic ...

Bangladesh to dramatically expand technology that doubles efficiency of urea fertilizer use

... of Bangladesh has announced that it will expand urea deep placement (UDP)a technology that doubles the efficiency of urea fertilizer useto almost 1 million hectares (ha) ... or dry season. UDP is the insertion of large urea briquettes into the rice root zone after ...

HU scientist finds way to catch terrorists red-handed

... Applied Chemistry detects the home-made explosive urea nitrate. When sprayed on cotton swabs taken from ... a suspect, if they have had recent contact with urea nitrate, the chemical will turn a blood red hue. urea nitrate is a powerful improvised explosive, ...

Tips from the American Journal of Pathology

... L-FABP correlated with the level of acute kidney injury at significantly earlier time points than levels of conventional renal markers such as blood urea nitrogen (BUN) or urinary N-acetyl-D-glucosaminidase (NAG). In addition, L-FABP showed better correlation than BUN or NAG with final histological ...

Updated formula measures kidney function more accurately

... of what biochemical analyses are being used by their institutions to measure waste products excreted by the kidney, such as creatinine and blood urea nitrogen (BUN), and different analyses would yield different estimate formulas," said George J. Schwartz, M.D., chief of Pediatric Nephrology at the ...

Diatom genome helps explain success in trapping excess carbon in oceans

... other taxa." From plants, the diatom inherited photosynthesis, and from animals the production of urea. Bowler speculates that the diatom uses urea to store nitrogen, not to eliminate it like animals do, because nitrogen is a precious nutrient in the ocean. What's more, the tiny alga draws the ...
Urea in Biological Technology

Helix BioPharma to Present L-DOS47 Analytical Method Development Findings at 2009 AAPS National Biotechnology Conference

... a natural process in the body called the urea cycle, to produce an anti-cancer effect. It is ... called urease that essentially reverses the urea cycle by breaking down urea into metabolites that include ammonia and ...

Helix BioPharma to Present L-DOS47 Research Findings at the National Research Council of Canada's Eighth Annual General Meeting of the Genomics and Health Initiative in Saskatoon, Canada

... a natural process in the body called the urea cycle, to produce an anti-cancer effect. It is ... called urease that essentially reverses the urea cycle by breaking down urea into metabolites that include ammonia and ...

Helix BioPharma Corp. contracts KBI Biopharma to develop an L-DOS47 clinical packaging format

... a natural process in the body called the urea cycle to produce an anti-cancer effect. It is ... called urease that essentially reverses the urea cycle by breaking down urea into metabolites that include ammonia and ...

HU scientist finds way to catch terrorists red-handed

... Applied Chemistry detects the home-made explosive urea nitrate. When sprayed on cotton swabs taken from ... a suspect, if they have had recent contact with urea nitrate, the chemical will turn a blood red hue. urea nitrate is a powerful improvised explosive, ...

Hyperion Therapeutics, Inc. Announces Senior Management Team and $15M Financing Event

... trials of GT4P for potential use in urea cycle disorder (UCD) and hepatic encephalopathy ... in patients with deficiencies in enzymes of the urea cycle. The most common adverse reactions ... in the chronic management of patients with urea cycle disorders involving deficiencies ...

Hyperion Therapeutics Secures $40 Million In Series B Round

... and hepatology therapies for the treatment of urea Cycle Disorders (UCD) and Hepatic Encephalopathy ... "The unmet medical need for patients with urea Cycle Disorders and Hepatic Encephalopathy remain ... Le Mons, Executive Director of the National urea Cycle Disorders Foundation commented, "We are ...

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Urea in Biological Products

Marker for 2D Electrophoresis from Sigma-Aldrich

Description:... in this marker have been selected to provide a diagonal pattern across a 2D gel. The pI range is 7.6 to 3.8. Mol wt: 17,000-89,000 Physical Form: urea ...
Company:Sigma-Aldrich
Urea in Biological Definition

Urea cycle

... The urea Cycle is a cycle of biochemical reactions occurring in many animal organisms that produces urea from ammonia . This cycle, also known as ... cycle discovered (Krebs and Hensenleit, 1932) urea is much less toxic than ammonia, therefore ...

Dialysis

... In medicine , dialysis is a method for removing waste such as urea from the blood when the kidneys are incapable of this, i.e. in renal ... of glucose, amino acids and mineral ions. The solution is sterilized. urea diffuses into the dialysing fluid, which does not contain the compound. ...

Homeostasis

... , various ions , oxygen , and wastes, such as carbon dioxide and urea . Since these properties affect the chemical reactions that keep bodies ... take in oxygen and give off carbon dioxide . The kidneys remove urea , and adjust the concentrations of water and a wide variety of ions . ...

Nephron

... filtrate , contains water , glucose , salt , amino acids , and urea . Proximal tubule The valuable molecules, water , glucose , salt ... urine. Lower portions of the collecting duct are also permeable to urea , allowing some of it to enter the medulla of the kidney , thus ...

Biochemistry

... the discovery of the first enzyme , diastase , in 1833 by Anselme Payen . In 1828 , Friedrich Whler published a paper about the synthesis of urea , proving that organic compounds can be created artificially, in contrast to the common belief of the time that organic compounds could only be ...

Enzyme

... Tyrosine kinases : those enzymes which transfer phosphate groups to a tyrosine residue in a protein Tyrosinase Urease : hydrolizes urea into carbon dioxide and ammonia Xanthine oxidase : oxidizes hypoxanthine to xanthine and further to uric acid Purification ...

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Urea in Biological Dictionary

Urea cycle

... The urea cycle is a cycle of biochemical reactions occurring in many animals that produces urea (NH2)2CO from ammonia (NH3). This cycle was ... metabolic cycle discovered . In mammals, the urea cycle takes place only ... An ...

Urea

... urea or carbamide is an organic compound with the ... joined by a carbonyl (-CO-) functional group. urea n. A water-soluble compound, CO(NH 2 ) 2 , that ... metabolism and is the chief nitrogenous urea cycle n. The sequence of chemical reactions ...

Tobacco mosaic virus

... causes mosaic disease in ... Tobacco mosaic virus - Wikipedia, the free encyclopedia ... Disintegration of tobacco mosaic virus in urea solutions" ... After the double helix: Rosalind Franklin's research on Tobacco mosaic virus " ... ... the best known examples of this is the ...

Glomerulus

... wastes pass into the tubule and become ... Blood leaving the glomerulus passes into a second capillary network (not shown ... only 50% of the urea filtered at the glomerulus is reclaimed ... Renin Release by Kidney Glomerulus ,Afferent arteries from the glomerulus release renin, an ...

Endonuclease

... including the families contained in it. Additional information provided includes InterPro ... Endonuclease V is also active toward abasic and urea sites, base pair mismatches, ... At low concentrations, Endonuclease V first nicks a DNA strand at the lesions ... An endonuclease of ...

Denaturing Gel

... in the absence of SDS. ... ... there were 2 bands on the non- denaturing PAA gel (Fig. 41) ... Denaturing PAA gels. Denaturing 6% PAA/7M urea sequencing gel can be easily used to separate ... Laboratory equipment and supplies, including Denaturing Gel Mix, 6%. Choose from ...

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