Navigation Links
Untranslated in Medical News

Monitoring whether patients take medicines can help anticipate HIV treatment failure in Africa

... Related PLoS Medicine Perspective article: Citation: Hughes TA, Jones PF (2008) Regulatory RNAs: Have mRNA untranslated regions joined the party? PLoS Med 5(5): e110. doi:10.1371/journal.pmed.0050110 IN YOUR COVERAGE PLEASE LINK TO THIS URL, WHICH WILL PROVIDE ...

Drug Strategy Makes Cancer Genes Get Lost in Translation

... machinery that does the translating, making it a challenge to determine where to begin, he added. In contrast, strong mRNAs have only short 5' untranslated regions that allow for easier protein formation. The successful translation of weak mRNAs therefore depends more heavily on other protein factors, ...
Untranslated in Biological News

Modification of program enables prediction of gene transcription

... the protein sequences produced by genes and their untranslated regions. Researchers in recent years have grown increasingly enthusiastic about the significance of untranslated regions. By understanding the functions of these ... protein- coding region. Most of this extra-long untranslated region is then discarded by splicing the ...
Untranslated in Biological Technology

Get the 5'-End

... for translation is obvious, but without knowledge of the 5' untranslated sequence, it is difficult to be certain that 'an' AUG in the cDNA sequence is 'the' AUG start site. The upstream, untranslated region will typically contain stop codons in-frame with the ...

Getting Started with MicroRNA Research

... represses protein translation by binding to sequences in the 3' untranslated region of specific mRNAs. The exact mechanism of translation ... miRNA activity levels. The cloning site in the 3' untranslated region (3' UTR) of the luciferase gene allows ...

The GeneZoo or the GeneJungle?

... splice variants, which occur less frequently in the 3 untranslated regions of transcripts (Table 1). Utilizing the 3 sequences as ... cluster sequences from different gene family members, since the untranslated regions tend not to align. In contrast, sequencing artifacts are ...

FlexiPlate siRNA

... shown that off-target effects are frequently caused by matches of the seed region of the siRNA antisense strand with the 3' untranslated region of mRNA (2). siRNA designs are analyzed for 3' UTR/seed region complementarity and siRNAs with the least potential to cause ...

The let-7 microRNA Family Regulates RAS: Implications for Development and Oncogenesis

... identified genes, let-60/RAS stood out because it has eight LCSs and ten nonconforming sites in the 3' untranslated region (3'UTR), as well as three LCSs in the coding sequence. The role of let-60/RAS in C. elegans ...

MicroRNA Profiling by Array Analysis Reveals Critical BioMarkers

... least two genes, lin-14 and lin-28 [13]. The activity of lin-4 depends on the partial homology of the miRNA to specific regions of the 3' untranslated regions (UTRs) of lin-14 and lin-28 mRNAs [5, 14]. Additional miRNAs have been functionally characterized (Figure 2). The range ...

miRNA Expression in White Blood Cells

... are endogenous, 21-24 nt RNAs that mediate post-transcriptional gene regulation by pairing with the 3' untranslated region of messenger RNAs and acting as translational repressors. The study of miRNA is an emerging and ...

Detecting miRNA & siRNA

... regulation. Some of these miRNAs (e.g. lin-4 and let-7 ) inhibit protein synthesis by binding to the 3' untranslated region of target mRNAs. Others bind to perfectly complementary mRNA sequences to destroy target transcripts ...

Cancer-Related miRNAs Uncovered by the mirVana miRNA Microarray Platform

... specific miRNAs might be participating in cancer through the mis-regulation of oncogenes, we scanned the 3' untranslated regions (UTRs) of 150 well-known oncogenes for sequences with significant homology to the miRNAs identified ...

Human Universal cDNA Library Array I

... to hybridize to the beginning of the 5 translated region (ATG included) while the other corresponded to the end of the 3 untranslated region ( Figure 5 and Figure 6 ). The percentage of full-length cDNAs was determined by comparing the two results. ...

More>>

Untranslated in Biological Definition

Barr body

... X inactivation centre or Xic , usually found near the centromere . The centre contains twelve genes, seven of which code for proteins , five for untranslated RNAs , of which only two are known to play an active role in the X inactivation process, Xist and Tsix. The centre also appears to be important ...

Morphogenesis

... factors. Bicoid has a DNA-binding homeodomain that binds both DNA and the nanos mRNA. Bicoid binds a specific RNA sequence in the 3' untranslated region of caudal mRNA and blocks translation. Hunchback protein levels in the early embryo are significantly augmented by new hunchback gene ...

Morphogenesis

... factors. Bicoid has a DNA-binding homeodomain that binds both DNA and the nanos mRNA. Bicoid binds a specific RNA sequence in the 3' untranslated region of caudal mRNA and blocks translation. Hunchback protein levels in the early embryo are significantly augmented by new hunchback gene ...
Untranslated in Biological Dictionary

Untranslated RNA

... protein synthesis: ... DsrA is a small untranslated RNA that regulates expression of two global ... The untranslated RNA DsrA regulates at least two global ... by ... An RNA domain within the 5' untranslated region of the tomato bushy stunt virus ... of ...

Untranslated region

... The five prime untranslated region (5' UTR), also known as the leader ... of the coding region . ... The three prime untranslated region (3' UTR) is a particular section of ... It follows the coding region . Five prime untranslated region The five prime ...

Leader sequence

... a sequence of mRNA ... The five prime untranslated region (5' UTR), also known as the leader ... shorter than that of LV and ... Five prime untranslated region The five prime untranslated region ( 5' UTR ), also known as the leader ...

Triplet repeat expansion

... ... Triplet Repeats in Noncoding Regions Fragile X syndrome (CGG repeat ) Fragile ... is caused by the expansion of a (CGG)n repeat in the 5′ untranslated region ... Fragile X Syndrome Triplet Repeat Expansion Disease ... Trinucleotide repeat expansion and human disease. Annu. Rev. ....

Start codon

... AUG is the start codon , methionine is therefore the first amino acid of many proteins. The start codon is almost always preceded by an untranslated region ... Determining the accuracy of start codon prediction is more ... start codon predictions on Escherichia coli genes using ... ...

Gene insertion

... changes the number of DNA bases in a gene by adding a piece of DNA. ... This insertion occurs in a part of the gene known as the 3' untranslated region, ... DNA ; extracellular ; extracellular matrix ; gene ; insertion ; kilobase ; ... Gene , insertion ,biological ,biology ...

More>>

Other Contents
(Date:12/17/2014)... (PRWEB) December 17, 2014 This ... private practices that have made outstanding and innovative ... support and progression of private practice physical therapy ... Physical Therapy Association. , On behalf of Performance ... owner and CEO of Performance accepted the award ...
(Date:12/17/2014)... A group of 127 scientists sent an “open ... to a recent statement by the center that was highly ... the efficacy of all brain exercises. , Signatories to the ... the center’s statement critical of brain exercise companies that overstate ... its case, in a document it had entitled “A Consensus ...
(Date:12/17/2014)... (PRWEB) December 17, 2014 No matter ... been able to eradicate the head louse parasite—a common ... for parents. Each year between six and twelve million ... the Miami-based lice removal treatment company comes to the ... and environmentally friendly. With its track record of customer ...
(Date:12/17/2014)... 17, 2014 Project Veritas is releasing ... videos of MIT economist and Obamacare architect Jonathan Gruber ... O’Keefe conducted the interview, which is being distributed on ... was intentional mislabeling in the Affordable Care Act in ... A two-hundred-and-fifty billion dollar per year tax grab. , ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, 2014 (HealthDay ... phenomenon is when an illness that originated in animals jumps ... -- is not uncommon and keeps researchers on their toes ... make inroads into the human population. A new report ... in this case were guinea pigs. More specifically, they were ...
Breaking Medicine News(10 mins):Health News:Performance Physical Therapy Awarded with Jayne L. Snyder Private Practice of the Year 2014 2Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 2Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 3Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 4Health News:Lice Troopers Announces New Lice Treatment Clinic in Coral Gables to Service Key Biscayne, Coconut Grove, Kendall, Brickell & South Miami 2Health News:Project Veritas: James O’Keefe Interviews the Man Who Discovered Jonathan Gruber Videos 2Health News:Guinea Pigs Can Be Source of Serious Strep Infection 2Health News:Guinea Pigs Can Be Source of Serious Strep Infection 3
(Date:11/18/2014)... The Parenteral Drug Association (PDA) today confirmed that seven officials ... least seven more will participate in the upcoming 2014 PDA ... Washington D.C. , Dec. 2-4. ... the regulatory agencies in the United States ... to help advance the use of metrics in the regulatory ...
(Date:11/15/2014)... , Nov. 13, 2014  While we may still be ... McCoy used in "Star Trek" to gain instant access to ... to work with smartphones and tablets for monitoring and measuring ... healthcare world. This may seem a tad Orwellian to some, ... adopt some of these technological opportunities into their healthcare regime. ...
(Date:11/11/2014)... CHICAGO , Nov. 11, 2014  Forensicon, Inc., ... eDiscovery firm, is pleased to announce the promotion of ... to Director of Digital Forensics. In Schiff,s new role ... out the team of digital forensics examiners and provide ... Photo - http://photos.prnewswire.com/prnh/20141110/157719 ...
Breaking Biology News(10 mins):FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2
Other TagsOther Tags