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Transposable in Medical News

Scientists Map Genome Sequence Dengue Mosquito

... of Notre Dame. Zhijian Tu, a co-author and member of the Vector-Borne Infectious Disease Research Group at Virginia Tech, helped annotate transposable elements (TEs), genetic material that move around the mosquitos genome and have a significant impact on its structure and size. Another ...
Transposable in Medical Technology

Lorus Therapeutics Announces Scientific Presentations for Lead Antisense and siRNA Drug Candidates at International Cancer Conference

... as a potential therapy for a variety of diseases including cancer. From an evolutionary perspective, RNAi helps protect cells from viruses and transposable genetic elements in addition to carrying out more routine cellular tasks essential to development and growth. In mammalian cells siRNAs have ...
Transposable in Biological News

After dinosaurs, mammals rise but their genomes get smaller

... for the long terminal repeat (LTR) sequences of transposable elements, a curious sort of "jumping" genetic ... of mammalian and non-mammalian genomes. transposable elements often lose their functionality soon ... common. In the human genome, for example, transposable elements constitute as much as 45 percent of an ...

New research shows how gene function drives natural selection in important class of genetic elements

... function is driving the evolution of one kind of transposable element called the LTR retrotransposon. (LTR ... evolutionary pressures between host genome and transposable element will in the future be of interest to ... been known for a long time that the insertion of transposable elements can harm the host, but few studies have ...

Researchers piggyback to safer reprogrammed stem cells

... into the Epi-stem cells, they turned to a special type of DNA, called a transposable element, which can insert itself into an organism's DNA and carry a cargo with it, in this case Klf4. The transposable element Smith and colleagues used in their study is called Piggybac, which ...

Scientists discover small RNAs that regulate gene expression and protect the genome

... they act as a kind of immune system to suppress genetic interlopers called transposable elements, which were discovered at CSHL by Nobel laureate Barbara ... RNAs. The new small-RNA class both modifies gene activity and suppresses transposable elements, thus serving as a defense mechanism. These findings, the ...

'Junk' DNA proves functional

... called 'transposable elements' that are able to jump from one site to another at certain times in the history of the organism. The families of these transposable elements vary from species to species, as do the distributed DNA segments which bind the regulatory proteins." Dr. White also added, "This ...

Kansas state flower receives scientific attention

... species grow in extreme environments, Ungerer hypothesizes that environmental stress may have caused the activation of a typically inactive class of transposable elements of DNA, called long terminal repeat retrotransposons. "These elements are DNA sequences related to infectious retroviruses and are ...

Common aquatic animals show extreme resistance to radiation

... in high-school biology classes, bdelloid rotifers are highly unusual in several regards: They appear to be exclusively asexual, have relatively few transposable genes, and can survive and reproduce after complete desiccation at any stage of their life cycle. Meselson and Gladyshev hypothesize that it's this ...

Present-day species of piranha result from a marine incursion into the Amazon Basin

... at different spatial and temporal scales, is responsible for the diversification of the piranhas. This is an evolutionary progression which should be transposable to other fish communities inhabiting South American waters. ...

Selfish DNA and the Genetic Control of Vector-Borne Diseases

... of deadly pathogens to merely annoying pests. There are a number of naturally occurring selfish genetic elements. The most familiar of these are transposable elements, often called jumping genes, but more exotic examples include sex ratio distorters, and gamete killers. Each selfish element uses a ...

KGI professor contributes new insights on 'jumping genes'

... professor at the University of Zurich, were reported in the paper Transposon Excision from an Atypical Site: A Mechanism of Evolution of Novel transposable Elements. The work extends theories of the renowned cytogeneticist Barbara McClintock, who originally discovered moveable genetic elements. Rays ...

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Transposable in Biological Products

GPS -M Mutagenesis System from New England Biolabs

Description:... GPS-M Mutagenesis System enables you to insert a transposable element of your own design into your target DNA ... of target DNA molecules each containing the transposable element at a different position. To facilitate adaptation of the transposable element to your particular mutagenesis ...
Company:New England Biolabs
Transposable in Biological Dictionary

Transposable element

... Genetic transformation of Drosophila with transposable element vectors" ... A wiki specially dedicated to transposable elements and their classification ... transposable element . filipina. wahm. scientist-on-hold. ...

Inverted repeat

... repeat . ... Miniature Inverted - repeat transposable Elements (MITEs) (Class III) Transposons. in maize ... Miniature Inverted - repeat transposable Elements (MITEs) ... Furthermore, we found ... , genes, testis, DNA ... inverted repeat transposable elements (MITEs) ... rice miniature inverted ...

IS element

... insertion sequence is a short DNA sequence that acts as a simple transposable element . Insertion sequences have two major characteristics: they are small relative to other transposable elements and only code for proteins implicated in the transposition ...

Inverted Repeats

... repeats , because ... ... also known as Miniature Inverted - repeats transposable Elements or MITEs. ... Inverted - repeat transposable ... characteristic inverted repeats of about ... 2. Inverted ...

Insertion sequences

... An insertion sequence is a short DNA sequence that acts as a simple transposable element. Insertion sequences have two major characteristics: they are small relative to other transposable elements and only code for proteins implicated in the transposition ...

Insertion Sequence

... An insertion sequence is a short DNA sequence that acts as a simple transposable element. Insertion sequences have two major characteristics: they are small relative to other transposable elements and only code for proteins implicated in the transposition ...

Transposon mapping

... syndromes. ... TRAMP is a software package for generating transposon maps that are used for DNA sequencing. ... Chromosome Mapping . DNA transposable Elements. Software ... ... to a 466-bp region which spans nucleotides 15215 to 15681 on the transposon map . ... an intact chromosome-borne ...

Retrotransposons

... They are particularly abundant in plants, where they are often a principal ... 1.1 Class I: Retrotransposons . 1.1.1 Retroviruses as transposable elements ... Initially retrotransposons copy themselves to RNA (transcription) but, in ... Dan Voytas Lab at the University of Minnesota ... ...

Intergenic

... were unique to species ... We generated a set of 66 intergenic sequences in Arabidopsis lyrata, a close ... The intergenic regions included transposable element (TE) remnants and regions ... more problematic for intergenic regions of plant nuclear genomes, because plant ... In theory ...

Epigenetic

... arise during the lifetime of monozygotic twins. ... Provide information to researchers, students, and others about genomic imprinting. ... transposable elements and an epigenetic basis for punctuated equilibria ... Epigenetic mechanisms such as DNA methylation, histone ... an Epigenetic ...

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