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Transferrin in Medical News

Iron banded worms drying out of blood could be linked to Parkinson's and Alzheimer's

... Human blood relies on a protein called transferrin to safely transport iron through the bloodstream ... such as Parkinsons, Huntingtons and Alzheimers transferrin takes up iron out of bloodstream and transports ... to bind to two sites on the surface of the transferrin protein. It then curls around the iron and seals ...

Stretching exercises may reduce risk of pre-eclampsia during pregnancy

... provide protection against preeclampsia because stretchers produced more transferrin than walkers did, Yeo said. transferrin is a plasma protein that transports iron through the blood and protects ...

Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa

... of pregnancy should be discussed and the need for contraception evaluated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional ...

Diabetes, obesity and hypertension increase mortality in hepatitis C patients

... 40 U/L, AST> 37 U/L in men, and ALT> 31 U/L, AST>31 U/L in women), excessive alcohol use (>10 grams/day in women and > 20 grams/day in men), elevated transferrin saturation (>50%) and positive hepatitis Bs antigen were designated controls without liver disease. HCV patients were compared to HCV-negative ...

Iron overload: An important co-factor in the development of liver disease in alcoholics

... was found in alcoholics, which appeared to be related to the development of liver disease [odds ration for having liver disease in alcoholics with transferrin saturation greater than 45% was 2.2 (95% CI 1.37-3.54)]. Regarding HFE mutations, only H63D was found to be associated with alcoholic liver disease ...

UCLA and biotech company develop first blood test to measure key hormone that regulates iron

... The current tests do not measure hepcidin but instead measure some of its direct and indirect effects on iron and the iron-binding proteins transferrin and ferritin. The new blood test will directly measure hepcidin, offering more information to clinicians to help diagnose conditions and monitor the ...

Modeling Simulation Predicts Potential Negative Impact on U.S. Blood Supply if ESA Use Limited for Chemotherapy-Induced Anemia

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Updated Analysis of 2001 Epoetin Alfa Study Posted

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Ortho Biotech to Submit Official Request for Reconsideration to CMS Regarding ESA Coverage Policy

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...
Transferrin in Medical Technology

InVitria Showcases Cell Culture Productivity Enhancers at BioProcess International

... can replace bovine or human sources of albumin or transferrin and provide better productivity, enhanced safety ... -- Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, Lacromin is a ...

Siemens Healthcare Diagnostics Launches B12, Folate, and Ferritin Tests on Its Dimension vista Intelligent Lab System

... Iron Binding Capacity by photometric methodology; and Haptoglobin, Soluble transferrin Receptor, and transferrin testing by nephelometric methodology. The Dimension Vista Intelligent Lab ...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

... of pregnancy should be discussed and the need for contraception evaluated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional ...

Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Observational Studies Assess the Potential Impact of Limiting Erythropoiesis-Stimulating Agent Availability on Frequency of Blood Transfusions

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

New Data Highlighting Possible Impact of ESA Reimbursement Policies on Patient Care, Nation's Blood Supply, to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Data From Ortho Biotech-Sponsored Studies to be Presented at National Kidney Foundation 2008 Spring Clinical Meetings

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Ortho Biotech Statement on U.S. Food and Drug Administration Oncologic Drugs Advisory Committee Vote

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Totality of Available Data Reaffirms PROCRIT(R) (Epoetin alfa) Is Safe and Effective When Used Appropriately as Labeled to Treat Chemotherapy-Induced Anemia

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Observational Data Show Transfusion Patterns in Chemotherapy-Induced Anemia Patients Receiving Erythropoiesis-Stimulating Agents

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...
Transferrin in Medical Products

Transferrin

Description:... For the quantitative in vitro determination of transferrin in human ...
Company:Randox Laboratories Ltd.

Transferrin (Liquid)

Description:... For the quantitative in vitro determination of transferrin in ...
Company:Randox Laboratories Ltd.

Soluble Transferrin Receptor

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

Carbohydrate Deficient Transferrin for Congenital Glycosylation Disorders

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

Carbohydrate Deficient Transferrin for Alcohol Use

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

Glycosylated Transferrin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

Beta-2 Transferrin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories
Transferrin in Medical Definition

Atransferrinemia

... Atransferrinemia is a genetic disorder in which there is absence of transferrin , a plasma protein that transports iron through the blood . ... away from heart failure with atransferrinemia. The half-normal levels of transferrin in her parents ' bloodstream supported the notion that this disorder is ...
Transferrin in Medical Dictionary

Serum iron

... really transferrin-associated ferric iron. Each transferrin molecule can carry 2 iron atoms. Normally about ... sites are filled. This is called the percent transferrin saturation. Serum iron studies are blood ... by 8 per cent, serum iron by 17 per cent and transferrin saturation by 23 per cent as well as a decrease ...

Serum

... in the labor atory, is really transferrin-associated ferric iron. Each transferrin molecule can carry 2 iron atoms. Normally about 30% of the available sites are filled. This is called the percent transferrin saturation. Serum iron studies are blood tests that: measure the ...

Diphtheria

... Biologics Control Act), that required licensing of biologics establishments, ... A substance created by linking a form of diphtheria toxin to transferrin (a protein that binds to and is taken up by rapidly growing cells, such as tumor cells). Once inside, the toxin portion of the molecule kills ...

Ferritin

... is also stored as ferritin and hemosiderin in the bone marrow , spleen , and liver . levels by 8 per cent, serum iron by 17 per cent and transferrin saturation by 23 per cent as well as a decrease in the total iron binding capacity by 7 per cent. All of these changes were statistically ....

Hemochromatosis

... diagnosis . These include: Elevated serum iron Elevated TIBC (total iron binding capacity) Elevated serum ferritin Elevated percentage of transferrin saturation ... Hemochromatosis develops when the body builds up too much iron. The condition can be inherited, or acquired. Causes of aquired ...

Immunoelectrophoresis

... compares the clearance (for example, the rate that the kidney s excrete and clear the blood stream) of IgG (an antibody ), versus the clearance of transferrin (an iron-transport protein ). Immunoelectrophoresis - Urine Alternate Names : Gamma globulin Electrophoresis - Urine , IEP - Urine , ...

TIBC

... saturating all the available binding sites, it is possible to measure the total iron binding capacity ( TIBC ). This is really a measure of the transferrin in the serum . ...

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Transferrin in Biological News

Rusty worms in the brain

... A malfunction of the blood transporter transferrin may be to blame. A team led by Peter J. Sadler at ... (Kanpur, India) has now been able to show that transferrin can clump together to form wormlike fibrils. As ... The researchers deposited iron-loaded human transferrin onto various surfaces under conditions that ...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

... uses of transferrin. "We discovered that transferrin can bind to receptors on the intestinal ... stream," Shen says. "Humans naturally produce transferrin to move iron through the blood to the liver, ... After that, the researchers needed to bring transferrin and G-CSF together, a process that is detailed in ...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

... classic "Trojan horse" approach, a protein called transferrin that normally delivers iron into cells is ... through the bloodstream until it meets up with a transferrin receptor on the surface of another cell. The transferrin binds tightly to a receptor on the cell's ...

Discovery could lead to better control of hemorrhagic fever viruses

... lab by Jonathan Abraham, PhD, an MD-PhD student at HMS, turned out to be transferrin receptor 1 (TfR1), a well-known protein that is key in enabling cells to ... have shown that when the iron level in the body is low, the number of transferrin receptors in tissues increases. Consistent with these findings, Choe's ...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

... initiate a self-destruct process called apoptosis in cells with genetic damage. The liposome-antibody complex finds the cancer cell by binding to the transferrin receptor, which is present on the cancer cell surface in high numbers. When this happens, the p53 "payload" moves into the tumor cell. "If we ...
Transferrin in Biological Technology

InVitria's Animal Free Lacromin(TM) Provides a Cost-Effective Improvement Over Transferrin

... growth factor for cell culture media outperforms transferrin and provides a cost-effective solution to rising transferrin costs. Because Lacromin is produced in a ... to the challenge of rising transferrin costs and increasing concern over the use of ...

InVitria Further Strengthens Sales Team with Promotion of Brandy Sargent to Account Manager - Western United States

... cell media. -- Lacromin - Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, Lacromin is a strong growth promotant ...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... of pregnancy should be discussed and the need for contraception evaluated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional ...

Beckman Coulter Announces Fourth Quarter and Full Year 2008 Results; Earnings Outlook Achieved on Strong Fundamentals

... systems customers can choose from to meet a wide range of test mix and volume requirements. Received FDA clearance for the Access(R) Soluble transferrin Receptor assay and the sTfR/log ferritin index as aids in the diagnosis of iron deficiency anemia and anemia of chronic disease. Launched the ...

InVitria Touts Product Advantages at Cambridge's Cell Culture Conference

... media.(see http://www.Cellastim.com ) -- Lacromin - Lacromin is recombinant human lactoferrin, a growth factor that also delivers iron similar to transferrin in cell culture media. (see http://www.Lacromin.com ) -- Lysobac - Lysobac is a bacterial cell lysis agent that is more efficient and more ...

InVitria Sponsors Cambridge Healthtech's Optimizing Cell Culture Development Conference

... cell media and primary cell media. (see http://www.Cellastim.com ) -- Lacromin -- Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, Lacromin is a strong growth promotant as a cell culture ingredient in mammalian cell culture media. (see ...

InVitria Expands Sales Team

... also has been an effective component in stem cell media. -- Lacromin -- Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, at higher inclusion levels, Lacromin is a strong growth promotant as a supplement for mammalian cell culture ...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa)

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents

... should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from Recent FDA Advisory Committee Meetings

... should be discussed and the need for contraception evaluated. * Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or ...
Transferrin in Biological Products

Mouse Anti-Transferrin, N-terminus Monoclonal Antibody, Unconjugated, Clone 236-18241 from Meridian Life Science, Inc.

Description:... MAb to transferrin Dry Ice: No Preservative: NaN3 Availability When Not in Inventory: 14-21 Business ...
Company:Meridian Life Science, Inc.

Rabbit Anti-TRANSFERRIN RECEPTOR Polyclonal Antibody, Unconjugated from AbD Serotec

Description:... RABBIT ANTI transferrin ...
Company:AbD Serotec

Multiple Affinity Removal System from Agilent Technologies

Description:... more with just one device. With this revolutionary system, you can: Remove six targeted, high-abundant proteins: albumin, lgG, antitrypsin, lgA, transferrin and haptoglobin (representing 85-90% of total serum protein mass) Improve the results you get with protein separation methods such as 1DGE, 2DGE ...
Company:Agilent Technologies
Transferrin in Biological Definition

Fungus

... to: Fatty acid content of the skin . pH of the skin, mucosal surfaces and body fluids Epithelial turnover Normal flora transferrin Cilia of respiratory tract . When fungi do pass the resistance barriers of the human body and establish infections, the infections are ...
Transferrin in Biological Dictionary

Transferrin receptor

... transferrin receptor (TfR) is a carrier protein for transferrin . It is needed for the import of iron into the ... iron concentrations promote increased levels of transferrin receptor , to increase iron intake into the cell. ...

Serum

... Blood serum is blood plasma without fibrinogen or the other clotting factors (i. ... transferrin saturation = Serum iron / Total iron-binding capacity ... Serum may refer to: The serum is a fluid component of clotted blood and it lacks ...
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