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Toxin in Medical News

Genes key to staph disease severity, drug resistance found hitchhiking together

... S. aureus (MRSA), have discovered a potent staph toxin responsible for disease severity. They also found the gene for the toxin traveling with a genetic component of ... PSM toxin. The researchers hypothesized that the toxin was somehow connected to drug resistance. This ...

Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

... delivery of a DNA encoding diphtheria toxin suicide gene. These nanoparticles were injected ... as scientists were able to deliver diphtheria toxin genes, using a nanoparticle, to the actual tumor ... selective activity in the cancer cells (how the toxin genes were regulated once inside the cells). ...

Photos: Don't Let Them See You Sweat This Summer

... administer treatment with BOTOX((R)) (Botulinum toxin Type A). Results last up to 6.7 months and ... Important BOTOX ((R)) (Botulinum toxin Type A) Information BOTOX((R)) is approved ... "Units" or "U" are different among the botulinum toxin products; clinical doses expressed in units are ...

Cepheid Receives FDA Clearance for First On-Demand Molecular Diagnostic Test for Clostridium difficile Infection

... use. Instead, many use less labor-intensive toxin EIA (enzyme immunoassay) and GDH (glutamate ... from stool specimens. The test targets the toxin B gene, discovered in 1978 to be the cause of antibiotic-associated diarrhea and colitis. The toxin B ( tcdB ) gene is the critical component of all ...

New Survey Reveals High Expectations for Popular Aesthetic Injections

... were interested in receiving aesthetic botulinum toxin injections within the next six months.(1) ... many expressed reluctance to having a botulinum toxin injection. In fact, one-third of those who had ... who would ever consider receiving botulinum toxin injections cited that a guarantee of ...

Competing With Botox - What Is On the Horizon?

... near the eyes and thick bands in the neck. The toxin blocks the nerve impulses, temporarily paralyzing ... advancements in Botulinum Toxin: Topical toxin Developed by Revance Therapeutics: Michael Kane, ... a topical, non-injectable, form of Botulinum toxin developed by Revance Therapeutics. Dr. Kane will ...

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Toxin in Medical Technology

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... protect against lethal anthrax infection by its toxin neutralization activity that allows the ... the anthrax Protective Antigen (PA) of the lethal toxin complex produced by the bacterium. Preclinical ... with a similar potency for neutralizing anthrax toxin in vitro as was seen with serum obtained from ...

Data Demonstrate that Obagi Medical Products' Condition & Enhance Skin Care System is an Effective Complement to Facial Rejuvenation Procedures

... the Condition & Enhance System and botulinum toxin type A injections (i.e., Botox(R)) experienced a ... are independent of the effects of botulinum toxin type A, therefore supporting the benefit of using ... in combination with: -- Botulinum toxin type A -- Intense pulsed light therapy ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile

... in high density cultures, REP3123 inhibited toxin production at low concentrations (< 1 ug/mL) for ... as vancomycin and metronidazole did not reduce toxin production in these high density cultures even at ... recognize two disease-causing factors, toxin A ...

DOR BioPharma Receives EMEA Agreement on the Design of its Confirmatory Phase 3 Clinical Trial of orBec(R) in GI GVHD

... protect against the lethal effects of exposure to ricin toxin, botulinum toxin and anthrax. DOR's ricin toxin vaccine, RiVax(TM), has been shown to be well tolerated and immunogenic in ...

Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting

... in Europe have shown non-inferiority of NT-201 to one other botulinum toxin in the treatment of cervical dystonia," said Pappert. First Study ... double-blind studies in focal dystonia NT 201 and one other Botulinum toxin (BTXCo) have been used with a dose ratio of 1:1. The results demonstrate ...

PharmAthene Submits Proposal to BARDA in Response to Broad Agency Announcement for Advanced Research and Development for Valortim(R)

... known as the anthrax Protective Antigen (PA) of the lethal and edema toxin complexes produced by the bacterium. Preclinical studies suggest that ... of antibody after a month, with a similar potency for neutralizing anthrax toxin in vitro as was seen with serum obtained from subjects who had been ...

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Toxin in Medical Products

BD ColorPAC Toxin A C. difficile Rapid Toxin A Test

Description:... BD ColorPAC toxin A C. difficile Rapid toxin A Test gives your laboratory clear-cut results in ... C. difficile samples for testing, ColorPAC toxin A C. difficile ...
Company:BD Diagnostic Systems

ImmunoCard STAT!® EHEC Rapid Test

Description:... is the first one-step 20 minutes rapid test for the detection of Shiga toxin 1 and 2 produced by Enterohemorrhagic Escherichia coli in human ... with 92% sensitivity and 100% specificity. The separate result for toxin 1 and 2 is useful as the latter is associated to more severe clinical ...
Company:Meridian Bioscience, Inc.

C. Difficile Tox A/B II

Description:... and produces highly sensitive results detecting not only the more common toxin A+ samples, but also samples that are toxin A-/B+. It's easy to perform, produces no indeterminates and provides ...
Company:Inverness Medical Innovations

TOX A/B QUIK CHEK

Description:... >99% specificity compared to tissue culture. Because the test detects both toxin A and toxin B, the risk of false negative results due to A-/B+ strains is greatly ...
Company:Inverness Medical Innovations

Myobloc®(Botulinum Toxin Type B) Injectable Solution

Description:... Myobloc (Botulinum toxin Type B) Injectable Solution, the only Botulinum toxin Type B treatment available, has been demonstrated in numerous published ...
Company:Solstice Neurosciences, Inc.

Xpect Clostridium difficile Toxin A/B Test Kit

Description:... Remels newest member of the Xpect family, Xpect C. difficile toxin A/B, detects both toxin A and B in one rapid test. The simple-to-perform test requires no sample ...
Company:Remel Inc.

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Toxin in Medical Definition

Artificial induction of immunity

... growth but by bacterial production of a toxin . Tetanus toxin is so lethal that humans cannot develop immunity to a natural infection, as the amount of toxin required to kill a person is much less than is ...

Disease causative agent

... The term disease causative agent usually refers to a biological pathogen that causes a disease. Technically, the term can also refer to a toxin or toxic chemical that causes illness, however. ...

Family history (medicine)

... Consequences Not all positive family histories imply a genetic cause. If various members of the same family have been exposed to the same toxin , then they may develop similar symptoms without a genetic cause. If a patient has a strong family history of a particular disorder (or group of ...
Toxin in Medical Dictionary

Aflatoxin

... cancer in parts of the world where this myco toxin occurs in high levels in food . Aflatoxin ... cancer in parts of the world where this myco toxin occurs in high levels in ingested food . ... weapons program producing anthrax , botulinum toxin , and aflatoxin . During Operation Desert Storm, ...

Bacterial

... then you touch or rub your eye . bacterial toxin A toxic substance, made by bacteria , that ... neuritis ; endemic non bacterial ... ENDO toxin : A toxin present inside a bacterial cell . ENDPOINT: A ...

Botulism

... rare, but very serious condition. It's caused by toxin produced by bacteria called Clostridium ... dangerous form of food poisoning caused by the toxin of Clostridium botulinum. bovine ... ... injection s come from a substance botulism toxin . When used properly and appropriately, Botox ...

Clostridium

... preserved or canned food , where they produce toxin . When eaten, eventiny amounts of this toxin can lead to severe poisoning . ... detects the presence of C. difficile and toxin A, one of the two toxins the bacterium ...

Diphtheria

... with tetanus ," Congress passed the Virus - toxin law (also referred to as the Biologics Control ... created by linking a form of diphtheria toxin to transferrin (a protein that binds to and is ... cells, such as tumor cells). Once inside, the toxin portion of the molecule kills the tumor cells. ...

Entero

... ENTERO PATHY: An intestinal disease . ENTERO toxin : A toxic substance that causes gastrointestinal upset. Cholera toxin is an example of an entero toxin . ENT RY INHIBITOR: A drug that interferes ...

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Toxin in Biological News

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... delivery of a DNA encoding diphtheria toxin suicide gene. These nanoparticles were injected ... as scientists were able to deliver diphtheria toxin genes, using a nanoparticle, to the actual tumor ... selective activity in the cancer cells (how the toxin genes were regulated once inside the cells). ...

Scientists report first remote, underwater detection of harmful algae, toxins

... detection of a harmful algal species and its toxin below the ocean's surface. The achievement was ... for organism identification as well as the toxin needed to assess the risk to humans and wildlife. ... molecular-based measurements of species and toxin abundance, and transmits results to the ...

Monash scientists debug superbug

... accepted scientific belief, our results show that toxin B, which was considered the less important toxin is actually the toxin that causes disease," Professor Rood said. ...

NYU scientists discover dangerous new method for bacterial toxin transfer

... parasites as secret pipelines for transferring toxin genes to vastly different bacterial species. ... species could engage in phage-mediated toxin gene transfer. "We happened to be looking at ... nasty toxic shock toxin. As far as we know, this toxin is produced only by Staphylococcus aureus. No ...

Brown chemist finds gray mold's killer gene

... its target in a velvety vise, releasing a toxin that poisons the host plants' cells, eventually ... Spain, has figured out how the fungus's deadly toxin is made and how it might be disarmed naturally. ... identified the set of genes that manufactures the toxin and in particular the central gene the fungus ...

Scripps research scientists identify blood component that turns bacteria virulent

... dioxide and sodium bicarbonate strongly induced toxin production in the laboratory setting. The ... "It was observed that the best medium for toxin production was one that people believed mimicked ... inside the cell greatly decreased, induction of toxin gene expression did not occur, and virulence in ...

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Toxin in Biological Technology

Bacteria pack their own demise

... have several tens of thousands of genes. toxin and antitoxin If your genetic information ... T-A genes contain instructions for both a toxin and its antitoxin. As long as the cell is ... located gets damaged or lost, the production of toxin and antitoxin comes to a halt and a time bomb ...

Medarex and Massachusetts Biologic Laboratories Announce Primary Objective Achieved in Phase 2 Trial of Monoclonal Antibody Combination for the Treatment of Clostridium difficile Associated Diarrhea (CDAD)

... Medarex to target and neutralize the effects of toxin A and toxin B, respectively, the toxins produced by the ... the requirement for anti-C. difficile toxin B antibody in addition to anti-C. ...

Novel compound may treat acute diarrhea

... signaling. "You start with one molecule of a toxin or a hormone," said Alexander Kots, Ph.D., the ... of the UT Health Science Center at Houston. "The toxin binds to a target and influences it. Soon you ... is called signal amplification. One molecule of toxin can produce millions of molecules of water." ...

Elusys' Anthim(TM) Dramatically Improves Survival of Animals Treated After Active Anthrax Infection

... monoclonal antibody targeting the anthrax toxin protective antigen. Elusys' Anthim is designed ... continued, "Death from the effects of anthrax toxin can occur in a few days if patients are not ... 'instant protective immunity' against the anthrax toxin in a bioterrorism emergency. We believe ...

Solstice Neurosciences, Inc. Issues Corporate Response to FDA Early Communication

... of patients treated with Myobloc(R) (Botulinum toxin Type B) Injectable Solution has always been ... regulations. Manufacturers of botulinum toxin products have recently submitted safety ... injected into an affected muscle, botulinum toxin type B inhibits the release of the ...

New Online Learning Tool Fills the Knowledge Gap on Botulinum Toxin Type B for Cervical Dystonia

... and knowledge with techniques around botulinum toxin injections lead to the best results for patients ... demonstrations with Myobloc(R) (Botulinum toxin Type B) Injectable Solution. The course can be ... review of the condition and the role of botulinum toxin type B," said Eric J. Pappert, MD, ...

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Toxin in Biological Products

Rabbit Anti-RAC2 Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.

Description:... ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein ...
Company:Proteintech Group, Inc.

Chicken Anti-Ras-related C3 botulinum toxin substrate 1 Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description:... Ras-related C3 botulinum toxin substrate ...
Company:GenWay Biotech, Inc.

PARP Inhibitor XI, DR2313 from Calbiochem

Description:... respectively) with little activity against the dehydrogenase activity of GAPDH, ADH, LDH, or the ADP-ribosylase activity of bacterial diphtheria toxin even at concentrations as high as 10 µM. Shown to inhibit H 2 O 2 -induced PAR formation and neuronal cell death in primary rat cerebral cortex ...
Company:Calbiochem

Sheep Anti-ESCHERICHIA COLI (STABLE TOXIN (ST)) Polyclonal Antibody, Unconjugated from AbD Serotec

Description: SHEEP ANTI ESCHERICHIA ...
Company:AbD Serotec

Mouse Anti-DIPHTHERIA TOXIN (A SUBUNIT) Monoclonal Antibody, Unconjugated, Clone 8G2 from AbD Serotec

Description: ANTI DIPHTH TOX A ...
Company:AbD Serotec
Toxin in Biological Definition

Escherichia coli

... such as streptomycin , so treatment with antibiotics is usually effective. Certain strains of E.coli are toxigenic (some produce a toxin very similar to that seen in dysentery ) and can cause food-poisoning usually associated with eating contaminated meat (contaminated during or ...

Monoclonal antibody

... cancer cells specific antigen and induce an immunological response on the target cancer cell. Such mAb could also be modificated for delivery of a toxin , radioisotope , cytokine or other active conjugate; it is also possible to design bispecific antibodies that can bind with their Fab regions ...

Shigella

... multiply intracellularly, and spread to contiguous epitheleal cells resulting in tissue destruction. Some strains produce enterotoxin and Shiga toxin (very much like the verotoxin of E. coli O157:H7 ). ...
Toxin in Biological Dictionary

Shigella

... in ... General information about the bacterium including infection, transmission, immunity and vaccines, incidences, pathogenesis, and Shiga toxin produced by the bacterium. General information about the infectious disease caused by a group of bacteria, how it is spread, and how it can be ...

Recombinant DNA

... Recombinant DNA form should be completed and submitted to the IBC, ... Formation of recombinant DNA containing genes for the biosynthesis of toxin ... Recombinant DNA summary with 15 pages of encyclopedia entries, essays, summaries, research information, and more. ... Get Recombinant ...

Recombinant

... Recombinant DNA form should be completed and submitted to the IBC, ... Formation of recombinant DNA containing genes for the biosynthesis of toxin ... Browse Pronto.com's most popular recombinant proteins offers. Compare and buy recombinant proteins products at the lowest prices. ...

Prophage

... in bifidobacteria: insights from genomics, transcription, ... Complete nucleotide sequence of the prophage VT1-Sakai carrying the Shiga toxin ... Prophage Finder initially uses BLASTX to compare input DNA sequences to a ... This Perl program predicts prophage by clustering BLAST hits ...

Masseter

... innervated by the masseteric nerve from the mandibular division ... Al-Muharraqi MA, Fedorowicz Z, Al Bareeq J, Al Bareeq R, Nasser M. Botulinum toxin for masseter hypertrophy. Cochrane Database of Systematic Reviews 2009, Issue 1. ... Information about masseter in the free online English ...

G2 phase

... FORM OF CELL DEATH IN T-CELLS ... of programmed cell death that kills T-cells in the G2 phase of the cell cycle. ... C. botulinum C2 toxin delays the G2 /M phase transition in synchronized HeLa cells. ... not allow one to distinguish between cells in G2 phase and cells in ...

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Other Contents
(Date:8/29/2014)... As reported by WKMS.com in the article ... municipal court drug has come up with a new strategy ... as the presiding judge in a Southeastern Ohio municipal court ... a medicated treatment option that can literally prevent them from ... Vivitrol, which blocks receptors in the brain that would normally ...
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(Date:8/28/2014)...  Privacy Advocate and Senior Staff Attorney at the ... the lineup of biometric and mobile commerce experts set ... Summit in Tampa, Florida on ... include Steven Rahman, Director, Technology and Strategy at Samsung, and ... theme of this year,s event is Mobility at the ...
(Date:8/28/2014)... WASHINGTON, Aug. 28, 2014A new method for measuring and ... help doctors and researchers better understand how drug abuse ... surgery and tissue engineering, and lead to better treatment ... by a team of researchers from Stony Brook University ... of Health, was published today in The Optical Society,s ...
(Date:8/28/2014)... mould in homes could pose a significant health risk to ... the Journal of Allergy and Clinical Immunology . , ... different countries, the research has found that the presence of ... asthma sufferers, as well as increasing the likelihood of developing ... team at the University of Exeter Medical School and is ...
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