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tolerance in Medical News

Is somatic hypersensitivity a predictor of irritable bowel syndrome?

... others have reported similar cold presser pain tolerance in IBS patients and controls. These conflicting ... area. Heat pain threshold (HPTh) and heat pain tolerance (HPTo) were assessed on the left ventral forearm ... significantly lower pain threshold and pain tolerance at both test sites. A unique finding of this ...

Microscopic 'beads' could help create 'designer' immune cells that ignore transplanted organs

... says. "It's like a calming effect and once tolerance is established, we don't need it any more." ... immune system, are good examples of the specific tolerance HLA-G affords, Dr. Horuzsko says. "We want to create in kidney transplant patients, the same tolerance to the new kidney." Within five years, HLA-G ...

Bayer CropScience and Monsanto Sign Cross Licensing Agreement on Herbicide Tolerance Traits in Rapeseed/Canola

... to cross license their respective herbicide tolerance traits in rapeseed/canola on a non-exclusive ... will grant Monsanto access to its LibertyLink(R) tolerance trait for use in canola. The agreement also ... on a non-exclusive basis, future herbicide tolerance traits and other agronomic traits that may be ...

Arete Therapeutics Presents Positive Clinical and Preclinical Data for AR9281

... exerts sEH mechanism-based improvement in glucose tolerance in preclinical models of type 2 diabetes. In ... blood pressure in patients with impaired glucose tolerance and hypertension to further corroborate the ... AR9281 inhibits sEH and improves glucose tolerance in a highly-dose dependent manner. ...

New Study Shows Long-Term Benefits for Patients with Pulmonary Arterial Hypertension

... shown to increase quality of life and exercise tolerance in individuals living with PAH; however, research ... drug therapy. Functional parameters and exercise tolerance were improved, and clinical worsening was reduced ... is intended to improve the symptoms, exercise tolerance and overall survival of PAH patients. Ambrisentan ...

Mom's Cells Prime Fetal Immune System

... strategies aimed at promoting immunological tolerance in human beings," he said. Modifying the ... HIV. Perhaps some aspect of the immunological tolerance of the fetal immune system explains how the baby ... may play a specific role in mediating immune tolerance to both self and foreign antigens encountered ...

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tolerance in Medical Technology

Spherix Announces Positive Phase 2 Study Results

... separate 3-hour oral glucose and tagatose tolerance tests. The subjects were also given 75 g of ... a novel hexose: Acute effects on carbohydrate tolerance in subjects with and without type 2 diabetes. ... participated in 11 separate 2-h meal or glucose tolerance tests. A total of 33 non-diabetic, healthy ...

Overweight Siblings of Children With Type 2 Diabetes Likely to Have Abnormal Blood Sugar Levels

... looked at the risk of abnormal glucose tolerance among siblings of children diagnosed with type 2 ... having abnormal glucose levels (impaired glucose tolerance or type 2 diabetes) than other overweight ... screening of obese children for abnormal glucose tolerance by primary care providers. This could also help ...

Genaera Corporation Presents Promising Preclinical Type 2 Diabetes Data for Trodusquemine (MSI-1436) at Keystone Symposia

... MSI-1436 leads to marked improvement in glucose tolerance and lowers plasma insulin levels in diet-induced ... and improves fasting blood glucose and glucose tolerance in hyperglycemic animal models, and that ... in glucose tolerance, as measured by oral glucose tolerance testing can be sustained during long periods of ...

Genaera Corporation Presents Additional Promising Preclinical Type 2 Diabetes Data for Trodusquemine (MSI-1436) at American Diabetes Association

... poster presentation, entitled "Trodusquemine (MSI-1436) Improves Glucose tolerance and HbA1C Levels in Murine Models of Insulin Resistance" concluded that ... dose of MSI-1436 demonstrated a significant improvement in oral glucose tolerance (OGTT) within 24 hours of dosing, and prior to any significant change in ...

Genaera Corporation Provides Highlights of Positive Phase 1 Trodusquemine (MSI-1436) Data from the North American Association for the Study of Obesity Annual Meeting

... pharmacodynamic impacts of the drug (improvement of abnormal glucose tolerance and appetite suppression) and to fully validate its proof-of-concept ... reduces body fat (with no reduction of lean mass), and improves glucose tolerance via inhibition of a unique combination of signaling pathways in a mouse ...

Genaera Corporation Presents Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting

... the first opportunity to study short-term glucose control indices, glucose tolerance and insulin sensitivity. The poster presented at NAASO, "First in Human ... reduces body fat (with no reduction of lean mass), and improves glucose tolerance via inhibition of a unique combination of signaling pathways in a mouse ...

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tolerance in Medical Products

FLEXILOG Gastrointestinal Single use pH catheters

Description:... one or two sensors. Flexilog single-use catheters are made from tubing measuring just 5.3 Fr or less than 1.8mm in diameter providing good patient tolerance whilst still providing the right stiffness for ease of intubation. This size makes one catheter suitable for both adult and pediatric use. They ...
Company:Oakfield Instruments, Inc.

Pyrex brand volumetric pipette, color-coded

Description:... These 25mL PYREX volumetric pipets were designed primarily for schools and laboratories where the Class A tolerance of No. 7100 is not required. They are constructed to the same wall thickness and length as our No. 7100, but have larger tip openings for faster ...
Company:Sigma-Aldrich

Boston Keratoprosthesis

Description:... performed. It is the most commonly used keratoprosthesis in the United States. The keratoprosthesis is made of clear plastic with excellent tissue tolerance and optical properties. It consists of two parts but when fully assembled, it has the shape of a collar button. (See picture above.) The device is ...
Company:Massachusetts Eye & Ear Infirmary

FlexNet™

Description:... data from multiple devices. Using this technology allows FlexNet to support comprehensive patient monitoring networks while providing superior noise tolerance and communications integrity. FlexNet can coexist with the hospital network or be installed as a separate ....
Company:Welch Allyn Medical Products

The EXTENDED FIT

Description:... the highest level of protection available. Techno-Aide offers the highest quality lead protective eyewear. Consistent lens thickness with only a + tolerance allowed. Mfg supervised by Licensed and Board Certified Opticians. All lens meet or exceed standards for optical clarity, visible light ...
Company:Techno-Aide

The WRAP AROUND

Description:... the highest level of protection available. Techno-Aide offers the highest quality lead protective eyewear. Consistent lens thickness with only a + tolerance allowed. Mfg supervised by Licensed and Board Certified Opticians. All lens meet or exceed standards for optical clarity, visible light ...
Company:Techno-Aide

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tolerance in Medical Definition

Central tolerance

... Central tolerance is the mechanism by which newly developing T ... "Receptor editing is the main mechanism of B cell tolerance toward membrane antigens". Nat Immunol 5 (6): ... APC • MHC Immunity • Autoimmunity • tolerance ( Central ) • Immunodeficiency ...

Thymocyte

... and are released into the circulation. Additional mechanisms of tolerance active in the periphery exist to silence these cells such as anergy , deletion, and regulatory T cells . If these peripheral tolerance mechanisms also fail, autoimmunity may arise. Thymus ...
tolerance in Medical Dictionary

Fasting

... 126mg/dl. The two hour value of an oral glucose tolerance test is greater than or equal to 200mg/dl. ... may be diagnose d using the oral glucose tolerance test . Overnight fasting is avoided by ... Glucose (Pre- Diabetes ) Impaired Glucose tolerance (Pre- Diabetes ) Impaired Vision (Visual ...

Glucose

... of glucose in the blood . The glucose tolerance test measures the body's ability to metabolize ... Images Urine Sample ... 3-Hour Glucose tolerance Test What is a 3-Hour Glucose tolerance Test ? How do I prepare for the test? What do I ...

Glucose tolerance test

... The glucose tolerance test measures the body's ability to metabolize ... & Images Urine Sample ... Oral glucose tolerance test : A test to determine the body's ability to handle glucose . 3-Hour Glucose tolerance Test What is a 3-Hour ...

Lactose

... with your healthcare professional. Lactose tolerance Test , Pediatric How can I prepare my child for ... the test? Lactose Intolerance Lactose tolerance Test Lactose A complex sugar found in milk ... be tested for more thoroughly using a lactose tolerance test , a hydrogen breath test and a stool ...

Lactose tolerance test

... Lactose tolerance Test , Pediatric How can I prepare my child for ... > Health > Tests & Exams > Lactose tolerance Test Lactose tolerance Test - ... ...

Agitation

... that can cause violent behavior . Repeated use increases an individual's tolerance to the drug . As tolerance builds, more of the drug is needed to achieve a desired effect by the ...

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tolerance in Biological News

REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

... demonstrated enhanced efficacy in transplantation tolerance induction in models of skin transplantation and ... today in a poster titled "Donor-Specific tolerance Induction by a Liposomal Formulation of KRN7000 ... in combination with Sirolimus in transplantation tolerance induction in mouse models. Study Results ...

A little java makes it easier to jive, researcher says

... Motl said, "is that when we found that caffeine tolerance doesn't matter, we were perplexed at first. Then ... of the literature relative to caffeine and tolerance effects across a variety of other stimuli. ... have that bigger, mental-energy effect. But the tolerance effect is not ubiquitous across all stimuli. Even ...

Bayhill Therapeutics and the Juvenile Diabetes Research Foundation announce research collaboration

... to evaluate safety, pharmacodynamics, immune tolerance and pancreatic function in patients with T1D. ... preservation as well as the induction of immune tolerance to pancreatic autoantigens. Clinical Trial ... C-peptide increase during screening mixed meal tolerance test, and presence of antibodies to at least one ...

MicroRNA implicated as molecular factor in alcohol tolerance

... noted NIAAA Director Ting-Kai Li, MD. tolerance is the decrease in sensitivity to alcohol that ... alcohol over time. Individuals who develop high tolerance (low sensitivity) to alcohol are at increased ... structure known as the BK channel develops tolerance to alcohol, particularly in the supraoptic ...

Drought tolerance in potatoes

... the genes and molecular mechanisms of drought tolerance in order to engineer new drought-resistant crops ... Bonierbale, are examining the genes for drought tolerance traits in several native Andean potato landraces. ... these genes contribute to the increased drought tolerance of the two clones under investigation. ...

Gates funding to help poor rice farmers

... have been confounded by the challenges of stress tolerance for decades, said Dr. Zeigler. But the ... itcan benefit from new varieties with sufficient tolerance of submergence, salinity, and stagnant flooding. ... of Japan (499.5 million$4.7 millionfor flood tolerance in Southeast Asia), Germanys Federal Ministry for ...

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tolerance in Biological Technology

Monsanto, BASF Scientists Disclose Discovery of Gene Conferring Drought Tolerance in Corn Plants

... the joint pipeline with other genes for drought tolerance as well as other abiotic stress tolerance traits. Among them is the second-generation ... and advance genes with promising yield and stress tolerance characteristics. Monsanto's discovery ...

Dow AgroSciences Confirms Efficacy of Zinc Finger Nucleases for Precise Genome Modification in Maize

... to enhance nutritional benefits and herbicide tolerance which will produce real benefits to farmers and ... The addition of a herbicide tolerance gene was targeted to disrupt ZmIPK1 in corn, an ... Research results confirmed the herbicide tolerance gene was inserted into the specified domain ...

BASF Sues DuPont for Patent Infringement

... and Company) for infringement of BASF's patented technology that confers tolerance to a key class of herbicides. Specifically, DuPont's Optimum GAT corn ... promoter which is an important genetic component that enables successful tolerance toward an herbicide class known as AHAS or ALS inhibitors. BASF Plant ...

Sangamo BioSciences Announces Publication in Nature of the Use of Zinc Finger Nucleases to Accelerate Precision Trait Stacking in Commercial Crop Species

... and Sangamo used ZFP Nucleases (ZFNs(TM)) to introduce a herbicide tolerance gene into a pre-determined address in the maize genome, simultaneously ... was disabled and permanently linked with the acquisition of herbicide tolerance - i.e. stacking the two desired characteristics in the plant and ...

Synvista Therapeutics Announces Progress in Phase 2 Clinical Trial Program for Alagebrium

... The study is designed to measure the effect of alagebrium on exercise tolerance in patients with chronic systolic heart failure. In addition, the Company ... alagebrium. "Based on our dialogue with the FDA, we believe that exercise tolerance is an approvable regulatory endpoint, in patients with systolic or ...

Phase 1b/2a Program Commences for RVX-208

... of Resverlogix. "This trial will continue to examine safety and tolerance as well it is a proof of principle study for ApoA-I production and HDL ... the required regulatory provisions that must be addressed such as safety, tolerance and pharmacokinetics, the study also will measure key reverse cholesterol ...

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tolerance in Biological Products

Nanoject II, 220 VOLT from Drummond Scientific Company

Description:... procedures into cells. Each Nanoject II Auto-Nanoliter Injector comes complete with 300 borosilicate capillaries that can be pulled to the required tolerance together with a back filling needle and maintenance kit. Automated Microprocessor controlled Microinjection Pipet delivering precise nanoliter ...
Company:Drummond Scientific Company

LabX Light Balance Software from Mettler Toledo, Inc.

Description:... and totalization applications *Job queue *Balance settings management *Instrument release control *Tolerances management with built-in tolerance ...
Company:Mettler Toledo, Inc.
tolerance in Biological Definition

Diabetes mellitus

... and insulin, a glucose 2 hours after 75 g of glucose, or a formal glucose tolerance test . Many health care recommendations for adults recommend universal ... mellitus type 2 can be evaded in those with only mildly impaired glucose tolerance 6 . Patients with type 1 diabetes mellitus require direct injection ...

Barbiturate

... slurred speech, loss of motor coordination, and impaired judgment. Depending on the dose, frequency, and duration of use, one can rapidly develop tolerance , physical dependence, and psychological dependence to barbiturates. With the development of tolerance, the margin of safety between the effective ...

Insulin

... resistance in cells requiring insulin for glucose absorption. This form of diabetes is strongly inherited. other types of impaired glucose tolerance (see the diabetes article) insulinoma or reactive hypoglycemia Insulin as a medication Principles Insulin is absolutely required ...

Punctuated equilibrium

... groups [that] are cut off from their parental stock ... selective pressures are usually intense because peripheries mark the edge of ecological tolerance for ancestral forms. Favorable variations spread ... "What should the fossil record include if most evolution occurs by speciation in ...
tolerance in Biological Dictionary

Central cell

... Central tolerance is the mechanism by which newly developing T ... are rendered non-reactive to self. Central tolerance is distinct from periphery tolerance in that it occurs while cells are still present ...

Abiotic stress

... > 1137 Lafitte > Abiotic stress tolerance in rice for Asia: ... low temperature is also a ... the most common responses for abiotic stress tolerance in plants are overproduction ... The aim is to ... ... Genetic Engineering for Abiotic Stress tolerance in Plants. How ... ... for Plant Abiotic ...

Biotic stress

... effect on NO ... Physiology and Biochemistry of Biotic Stress tolerance ... Biochemical targets for improved biotic stress tolerance in alfalfa ... Medicago Genomic Function and Response to Biotic ...

Variation

... Variation may be shown in physical appearance, metabolism, fertility, mode ... Taylor Enterprises, Inc. - Variation reduction, robust design, tolerance analysis, trending and acceptance sampling plan experts. Genetic variation is important because it provides the "raw material" for natural ...

Oviducts

... oviduct's full length. ... ... (PRs) in 41 human oviducts by immunohistochemistry. ... ER-positive IEL may be involved in regulating immune tolerance in tubal pregnancy oviducts . ... ...

Glucose

... in your bloodstream to fuel the ... Because neurons cannot store glucose , they depend on the bloodstream to deliver ... The oral glucose tolerance test (OGTT) measures the body's ability to use a type ... For more information, see the medical test Blood Glucose . ... Fact sheet about ... ...

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(Date:12/15/2014)... December 15, 2014 OutMarket , ... released “ Social Media Cheat Sheets ,” a guide ... that drives results on the top ten social media ... It helps drive awareness, engagement, and customer service. It ... to make an impact on new networks and weather ...
(Date:12/15/2014)... Steven Reinberg HealthDay Reporter ... large, new study should reassure the millions of American women ... for breast cancer. "There is no association between migraine ... associate professor of medicine at Harvard Medical School. "There is ... and there is no protective effect either." About 18 ...
(Date:12/15/2014)... The increase in prevalence of disabling hearing loss ... which is contributing to the growth in the global audiological ... of hearing loss and balance disorders are known as audiological ... speaker and amplifier. The global market is expected to grow ... period from 2014 to 2019. Some of the factors which ...
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(Date:12/10/2014)... 2014  Wake Forest Baptist Medical Center today announced plans ... of Medicine. Funding for this $50 million capital project ... be publicly launched next summer. The ... 60 series R.J. Reynolds Tobacco Company complex, adjacent to ... immediately with plans to be ready to welcome medical ...
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(Date:12/3/2014)... 2, 2014 As part of our commitment ... is pleased to announce the release of a new ... collect the workforce data that they need. ... left by existing readers. Many such devices have serious ... modern technology. Older models force users to navigate numerous ...
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