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Thyroid in Medical News

AstraZeneca Submits New Drug Applications for ZACTIMA(TM) in Second-Line Advanced Non-Small Cell Lung Cancer

... therapies in a range of tumour types, including thyroid cancer. Results from the ZEPHYR (300mg ... ZETA (300 mg monotherapy in advanced medullary thyroid cancer, Phase III) studies will be presented in ... an important growth driver in certain types of thyroid cancer. About Vandetanib Phase III ...

Increase in Thyroid Cancer Puzzles Experts

... screening doesn't entirely explain the jump in thyroid cancers noted in the United States since 1980, ... factors are to blame. A new study finds that thyroid tumors of all sizes are being picked up, not just ... he said. An estimated 37,200 new cases of thyroid cancer will be diagnosed this year, according to ...

News from Cancer

... or ellisp@karmanos.org INCREASE IN thyroid CANCER NOT EXPLAINED BY SCREENING ALONE Studies have reported an increasing incidence of thyroid cancer since 1980. One possible explanation for ... at the American Cancer Society analyzed thyroid cancer incidence between 1988 and 2005 using the ...

Slightly Underactive Thyroid May Be a Plus

... problem in need of treatment, an underactive thyroid in old age might actually help you live longer, a ... study says. Researchers tested the levels of thyroid stimulating hormone (TSH) in 236 Ashkenazi Jews, ... D.C. Hypothyroidism, or not enough thyroid hormone, can cause feelings of weakness, ...

Drug That Targets Vasculature Growth Attacks Aggressive Thyroid Cancer, Mayo Clinic Researchers Report

... benefits for some patients with aggressive thyroid cancer, research from Mayo Clinic indicates. ... of 37 patients with aggressive differentiated thyroid cancer treated with the drug pazopanib either ... to a degree we have not previously seen in thyroid cancer in response to other therapies, including ...

Drug that targets vasculature growth attacks aggressive thyroid cancer

... benefits for some patients with aggressive thyroid cancer, research from Mayo Clinic indicates. ... of 37 patients with aggressive differentiated thyroid cancer treated with the drug pazopanib either ... to a degree we have not previously seen in thyroid cancer in response to other therapies, including ...

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Thyroid in Medical Technology

deCODE Breakthrough in Thyroid Cancer May Enable More Targeted Risk Assessment and Earlier Intervention

... (SNPs) conferring substantial increased risk of thyroid cancer. The two SNPs, located on chromosomes ... SNPs, putting them at a 5.7-times greater risk of thyroid cancer than individuals who carry no copies of ... and they associate with altered levels of key thyroid hormones. "This is an important discovery ...

New Nexavar Data Presented in Multiple Tumor Types at 44th American Society of Clinical Oncology Annual Meeting

... cancer research, Dallas, TX. (abstract #8014). thyroid Cancer A Phase 2 Study of Sorafenib in Metastatic thyroid Carcinoma Findings from this single-arm Phase 2 ... partial responses) in patients with advanced thyroid cancer. In the study, Nexavar was well-tolerated; ...

Exelixis Reports Encouraging Phase 1 Data for XL184 at ASCO

... in Patients with Medullary thyroid Cancer CHICAGO, June 1 /PRNewswire-FirstCall/ ... and radiotherapy. "Patients with medullary thyroid cancer are a highly underserved population as ... multiforme are ongoing. About Medullary thyroid Cancer The American Cancer Society estimates ...

'Second Thoughts about Fluoride,' Reports Scientific American

... teeth, bones, the brain and the thyroid gland," reports Scientific American editors ... alter endocrine function, especially in the thyroid -- the gland that produces hormones regulating ... who chaired the NRC committee thusly, "The thyroid changes do worry me." Fluoride in foods, ...

Updated Phase 1 Data for Exelixis' XL184 Demonstrate Pharmacodynamic and Clinical Anti-Tumor Activity

... in patients with medullary thyroid cancer- SAN FRANCISCO, Oct. 23 ... the cutoff. Of seven patients with medullary thyroid cancer (MTC), three have had partial responses ... a marker frequently elevated in medullary thyroid cancer, and six of the seven patients had a ...

You May Have a Thyroid Problem and Not Know It - Particularly If You're Over 60, Says a New Harvard Medical School Report

... -- Doctors often mistake the symptoms of thyroid disease for another disorder such as heart ... from Harvard Medical School. The symptoms of thyroid diseases are so wide-ranging, particularly in older men and women, that doctors often overlook thyroid disorder as the cause and instead focus on ...

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Thyroid in Medical Products

ImmunoDOT Thyroid Autoimmunity Test

Description:... The ImmunoDOT thyroid Autoimmunity Test is an enzyme immunoassay (EIA) ... against human thyroglobulin and human thyroid peroxidase (microsome) in serum and heparinized ... blood and is used as an aid in the diagnosis of thyroid disorders. ...
Company:GenBio

Calcitonin IRMA Test

Description:... synthesized in the parafollicular C-cells of the thyroid gland and is packaged in secretory granules. The ... levels of calcitonin are characteristic of thyroid C-cell hyperplasia and medullary thyroid carcinoma [2,3]. Elevated serum calcitonin levels ...
Company:Diagnostic Systems Laboratories, Inc.

TSH ELISA Test

Description:... specificity. TSH stimulates production of thyroid hormones by binding to thyrocyte membrane ... of cAMP-dependent iodine transport and resultant thyroid hormone synthesis [2]. TSH secretion is ... at both the pituitary and hypothalamic levels by thyroid hormones. Low levels ...
Company:Diagnostic Systems Laboratories, Inc.

TSH IRMA Test

Description:... specificity. TSH stimulates production of thyroid hormones by binding to thyrocyte membrane ... of cAMP-dependent iodine transport and resultant thyroid hormone synthesis [2]. TSH secretion is ... at both the pituitary and hypothalamic levels by thyroid hormones. Low levels ...
Company:Diagnostic Systems Laboratories, Inc.

Total T4 RIA Test

Description:... synthesized within the follicular cells of the thyroid gland [1]. T4 is synthesized via a series of ... levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid hormones. IN: Division of Drugs and Toxicology, ...
Company:Diagnostic Systems Laboratories, Inc.

Total T4 EIA Test

Description:... synthesized within the follicular cells of the thyroid gland [1]. T4 is synthesized via a series of ... levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid hormones. IN: Division of Drugs and Toxicology, ...
Company:Diagnostic Systems Laboratories, Inc.

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Thyroid in Medical Definition

Pathology

... Skin - Stomach - Tailbone - Testicles - thyroid Morphology Papilloma / carcinoma - ... : endocrine diseases ( E00-35 ) thyroid Hypothyroidism ( Iodine deficiency , ... , Toxic multinodular goitre , Teratoma with thyroid tissue or Struma ovarii ) - Thyroiditis ( De ...

Ocular oncology

... . Other less common sites of origin include the prostate , kidney , thyroid , skin , colon lymphoma and leukemia . Types Tumors in the ... - Kidney - Ovaries - Skin - Stomach - Tailbone - Testicles - thyroid Morphology Papilloma / carcinoma - Choriocarcinoma - ...

Anterior mediastinal mass

... area is more likely to be malignant than those in other compartments (1) Most common masses found here include thymomas, germ cell tumors, lymphomas, thyroid tissue, and parathyroid lesions. The introduction to this article provides insufficient context for those unfamiliar with the subject matter. ...

Atransferrinemia

... retardation and recurrent infections are the first clinical signs of the disease. Iron overload occurs mainly in the liver, heart, pancreas , thyroid , kidney and bone joints , leading to mild to severe symptoms of liver and heart failure, arthropathy and hypothyroidism . Death may occur ...

Neurobiological Brain Disorder

... axis. Historically, other illnesses with previously unexplained etyiologies, when affecting brain function such as thyroid hormone dysfunctions, Multiple Sclerosis, and certain vitamin deficiencies, had also been considered "psychiatric" until diagnostic tests were ...

Nuclear medicine

... disease or provide palliative pain relief. For example, administration of Iodine-131 is often used for the treatment of thyrotoxicosis and thyroid cancer . Nuclear medicine differ from most other imaging modalities in that the tests primarily show the physiological function of the system ...

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Thyroid in Medical Dictionary

Alcoholism

... , aging , candidiasis , stress , allergies , thyroid problems, hypoglycemia , diabetes , and poor ... seizures alcoholism diabetes thyroid disorder others in which birth defects may be ... in people with , alcoholism , diabetes , and/or thyroid problems. Some studies indicate that as little ...

Anaplastic thyroid cancer

... Anaplastic thyroid cancer grows very rapidly and is an invasive type of thyroid cancer . It occurs most often in people over age 60. The cause is unknown. thyroid function tests are usually normal. ...

Aplastic

... of the disorder is unknown. An aplastic thyroid cancer grows very rapidly and is an invasive type of thyroid cancer . It occurs most often in people over age 60. The cause is unknown. thyroid function tests are usually normal. In ...

Autoimmune disease

... . A degenerative autoimmune disease of the thyroid gland that ultimately results in a marked reduction in the amount of thyroid hormone produced. hay fever ... Many other ... In the case of Grave's disease , the thyroid gland produces too ...

Autoimmune disorders

... as other conditions such as Bell's palsy and thyroid dysfunction. Symptoms ... Neil Williams and ... This test is performed to confirm the cause of thyroid problems or other autoimmune disorders . The ... in response to microsomes escaping from damaged thyroid cells. Children with acquired hypothyroidism ...

Caffeine

... It may also be a sign of overactivity of the thyroid gland or underlying disease . ... alcohol excess, stress , caffeine , overactive thyroid or excessive thyroid hormone intake, and certain drugs. ...

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Thyroid in Biological News

Specific genetic cause of fetal alcohol-related developmental disorders found

... with the genetic processes that control thyroid hormone levels in the fetal brain, a new animal ... during pregnancy decreases the level of maternal thyroid hormones and, therefore, fetal thyroid hormones. "Specific concentrations ...

First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal

... and monitoring of patients with Medullary thyroid Carcinoma (MTC), an uncommon and challenging form of thyroid cancer, have been developed by the American thyroid Association and published online ahead of print ...

Skip this cocktail party

... which are neurotoxicants known to disrupt the thyroid hormone system. The study also quantifies ... fluid in mammals. This protein plays a role in thyroid hormone transport throughout the brain, though its exact role is not known. thyroid hormone plays a key role in the development of ...

Smoking during pregnancy may impair thyroid function of mom and fetus

... harmful changes in both maternal and fetal thyroid function, according to a new study accepted for ... "We studied the influence of cigarette smoking on thyroid function of two groups of women at different ... is associated with changes in the mothers' thyroid hormone levels." Optimal ...

Researchers discover atomic bomb effect results in adult-onset thyroid cancer

... in some survivors who later developed papillary thyroid cancer as adults, according to Japanese ... kinase-signaling pathway may be sufficient for thyroid cell transformation and tumor development," said ... that have been shown to have an increase in thyroid cancer, and that children exposed to radioactive ...

Presence of gene mutation helps guide thyroid cancer treatment

... useful in predicting the level of aggression of thyroid cancer and help guide treatment options and ... frequently occurs in the most common type of thyroid cancer, conventional papillary thyroid cancer or PTC, but this is the largest study to ...

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Thyroid in Biological Technology

TSH Testing Raises Awareness of Importance of Thyroid Health

... to examine the link between nuclear reactors and thyroid disease near NYC was made at Croton on Hudson, ... it stepped up by permitting testing for elevated thyroid Stimulating Hormone (TSH), the first clinical ... "There are no standard testing programs for thyroid health in the U.S. even though the rate ...

SD Canada Announces CE Mark for ThyroChek(R) Adult and NeoNatal Tests

... Rapidly growing thyroid test market expands to EU, LATAM and Africa ... further open doors. The move will also build the thyroid health market, according to Sharon Cunningham, president of SD Canada: "Europeans know their thyroid gland. Food, such as bread in Russia, is marked ...

FDA Approves Additional Indication for Norditropin(R) for Small for Gestational Age (SGA) in Children

... such as hydrocortisone or cortisone acetate, thyroid hormone, insulin and/or oral diabetes medicines, ... and at the same time using glucocorticoids or thyroid hormone. If you are treated with insulin and/or ... monitored for progression of scoliosis. thyroid function tests should be performed periodically. ...

Exelixis Reaches Agreement with FDA on Special Protocol Assessment for XL184 Phase 3 Trial

... Pivotal Trial in Medullary thyroid Cancer Planned to Initiate This Summer SOUTH ... of XL184 as a potential treatment for medullary thyroid cancer (MTC) this summer. The phase 3 trial has ... renowned experts in the field of thyroid malignancies, including Dr. Steven Sherman from ...

Genzyme Announces FDA Approval of Thyrogen(R) for Use in Thyroid Cancer Ablation

... radioiodine to ablate, or destroy, the remaining thyroid tissue in patients who have had their cancerous ... patients commonly undergo when being treated for thyroid cancer. "This new indication extends the ... to patients during their initial treatment for thyroid cancer, in addition to its current use in ...

Bayer and Onyx Announce Nexavar Data Presentations at 45th American Society of Clinical Oncology Annual Meeting

... p.m.- 6:00 p.m., Level 3, W315A thyroid Cancer Effect of BRAFV600E on Response to Sorafenib in Advanced thyroid Cancer Patients Marcia Brose, M.D., Assistant Professor of ...
Thyroid in Biological Products

Mouse Anti-Thyroid Hormone Receptor beta 1 Monoclonal Antibody, Unconjugated, Clone J53 from Abcam

Description:... Mouse monoclonal [J53] to thyroid Hormone Receptor beta 1 ( Abpromise for all tested applications). entrezGeneID: 7068 SwissProtID: ...
Company:Abcam

Mouse Anti-Human Thyroid Hormone Rec., alpha1 / alpha2-Isotype Antibody, Unconjugated from ABR-Affinity BioReagents

Description:... Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of human thyroid hormone receptor, alpha1/alpha2-isotype. Storage: -20 C, Avoid Freeze/Thaw ...
Company:ABR-Affinity BioReagents

Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

Description:... D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors. Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. Studies ...
Company:ABR-Affinity BioReagents
Thyroid in Biological Definition

Infertility

... to female infertility are: General factors Diabetes mellitus , thyroid disorders, adrenal disease Significant liver , kidney disease ... Pretesticular causes Endocrine problems, i.e. diabetes mellitus , thyroid disorders Hypothalamic disorders, i.e. Kallmann syndrome ...

Albumin

... balance this, and thus need less albumin to maintain proper fluid distribution. Functions of albumin: Maintains oncotic pressure Transports thyroid hormones Transports other hormones, particularly fat soluble ones Transports fatty acids ("free" fatty acids) Transports unconjugated ...

Anatomy

... Patella Radius Skull Tibia Ulna Rib Vertebrae Glands : Ductless gland Mammary gland Salivary gland thyroid gland Parathyroid gland Adrenal gland Pituitary gland Pineal gland Tissues : Connective tissue Endothelial tissue ...

Cancer

... , rhabdomyosarcoma - in muscles , skin cancer (including benign moles and dysplastic nevi ), stomach cancer , testicular cancer , and thyroid cancer . Childhood cancers Cancer can also occur in young children, particularly infants. Here, the aberrant genetic processes that fail to ...

Down syndrome

... associated with the disorder include presence of a simian crease . Early educational intervention, screening for common problems such as thyroid functioning, medical treatment where indicated, a conducive family environment, vocational training, etc. can improve the overall development of ...

Enzyme

... to water Cytochrome c peroxidase takes reducing equivalents from cytochrome c and reduces hydrogen peroxide to water Deiodinase : activates thyroid hormones by the removal of iodine Diastase : break starch into glucose Dihydrofolate reductase : reduces dihydrofolic acid to ...

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Thyroid in Biological Dictionary

Thyroid gland

... The thyroid is one of the largest endocrine glands in the ... is found in the neck inferior to (below) the thyroid cartilage and at approximately the same level as the cricoid cartilage. The thyroid controls how quickly the body burns energy, ...

Response element

... as selective response elements for the thyroid hormone, retinoic ... nucleotide, and the ... of multiple response elements at the ... thyroid hormone response elements are DNA sequences that bind thyroid hormone ... T3 response elements have been ...

Parathyroid glands

... glands , which are usually located behind the thyroid gland, and, in rare cases, within the thyroid gland or in the chest. Parathyroid glands ... ... near or within the posterior surface of the thyroid gland and ... means that the parathyroid ...

Nodule

... where contact is most forceful. What is a thyroid nodule ? The thyroid gland is located in the lower front of the neck, ... nodule article " Healthcare Professionals ... thyroid NODULE ......

Hormones

... messenger that transports a signal ... The thyroid hormones , thyroxine (T4) and triiodothyronine (T3), are tyrosine-based hormones produced by the thyroid gland. An important component in the synthesis of thyroid hormones is iodine. The major form of ......

Hormone

... Protein polypeptide hormone that ... thyroid hormone and cortisol insufficiency are ... ... vasopressin, arginine vasopressin, AVP) ... thyroid hormone disorders: focusing on the role of thyroid hormone in the body ... For ...

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(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
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