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Tetracycline in Medical News

Synthetic gene circuit allows precise dosing of gene expression

... circuit starts with a promoter that launches the tetracycline repressor gene, which then blocks yEGFP via a ... to the cell culture in measured doses stifles the tetracycline repressor and permits expression of yEGFP. ... that used for yEGFP. This, in effect, turns the tetracycline repressor back on itself, a negative feedback ...

Avidas(TM) Pharmaceuticals and LaRon(TM) Pharma Inc. Announce Co-Promotion Agreement

... should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent discoloration of the teeth ...

Summertime Sun Exposure Can 'Burn' Acne Sufferers in More Ways than One

... should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of the teeth ...

FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia

... in patients with known hypersensitivity to tigecycline TYGACIL should be administered with caution in patients with known hypersensitivity to tetracycline class antibiotics TYGACIL is structurally similar to tetracycline-class antibiotics and may have similar adverse effects. Such effects may ...

E. coli engineered to produce important class of antibiotic, anti-cancer drugs

... compounds produced by living organisms; many are the active ingredients in pharmaceuticals. Bacterial aromatic polyketides include the antibiotic tetracycline and the compound doxorubicin, used in the treatment of breast and other cancers. Because many of these natural products are synthesized by ...

AVMA Addresses Livestock Health Issues Before U.S. Congress

... testified in June at a U.S. Senate hearing on antibiotic resistance and mollified concerns that the use of antimicrobials -- such as penicillin and tetracycline -- in food animals leads to human resistance. Dr. Hoang today reiterated the benefits of maintaining animal health with the use of antibiotics. ...

Study suggests antibiotic may prevent dreaded brain fever

... it is logistically difficult to transport vaccines in larger quantities from CRI to the location of epidemic. On the other hand minocycline, a tetracycline is easily available in pharmacy or in a primary health care center, in even very rural and remote set up and it is also inexpensive. This study ...

Antibiotic Shows Promise as Stroke Treatment

... Argye Hillis, a professor of neurology at the Johns Hopkins University School of Medicine in Baltimore. The drug in question is minocycline, a tetracycline derivative that has been used for years to fight bacterial infections. Over the past decade, the drug has also been shown to be effective in animal ...

Treating Tetracycline Stains Made More Affordable With New Treatment

... public to avoid embarrassment. Stains caused by tetracycline can be very unsightly, but treating these stains ... during his discussion titled "Treating tetracycline Staining in the Adult Dentition" to be presented ... pattern on their patient's teeth. In the 1950s, tetracycline stains reached widespread levels because so many ...

Tigecycline – New Generation Tetracycline With Broad Spectrum Antibacterial Activit

... which belongs to the family of new generation of tetracycline known as Glycycline. // Due to ... many drugs including the different analogues of tetracycline and Vancomycin. Drug – Tetracycline: ... their initial widespread use, a high incidence of tetracycline resistance among many bacteria has led to ...

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Tetracycline in Medical Technology

Paratek Reports Positive Phase 2 Clinical Data on its New Antibiotic PTK 0796 in Late Breaker Presentation at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy

... chemistry techniques, AMCs were evolved from tetracycline antibiotics as potential agents to combat ... activity of the tetracyclines while overcoming tetracycline and multi-drug resistance. Representing one of ... is a broad-spectrum antibiotic derived from the tetracycline class with oral and IV formulations that is being ...

Paratek to Present Clinical Data in Late Breaker Presentation at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy

... is a broad-spectrum antibiotic derived from the tetracycline class with oral and IV formulations that is ... also developing other broad- and narrow-spectrum tetracycline antibiotics to treat hospital and community infections based on its novel tetracycline chemistry expertise. Outside of ...

Paratek Pharmaceuticals Announces the Close of $40 Million Private Placement to Finance Programs to Combat MRSA Infections

... is a broad spectrum antibiotic derived from the tetracycline class with oral and IV formulations that is being ... difficile associated-diarrhea based on its novel tetracycline chemistry expertise. Outside of its tetracycline program, Paratek has also identified ...

Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs

... IND application to begin a Phase I/IIA clinical trial in SMA Type I." tetracycline Program: According to Paul Higgins, Ph.D., Director, Inflammation Drug ... the research at Paratek for the previous three years for our work on tetracycline derivatives as a potential treatment of SMA. These compounds are intended ...

Wyeth Receives Approvable Letter from FDA for TYGACIL for the Treatment of Patients with Community-Acquired Pneumonia

... administered with caution in patients with known hypersensitivity to tetracycline class antibiotics -- Glycylcycline class antibiotics are structurally similar to tetracycline class antibiotics and may have similar adverse effects. Such effects ...

More Clinical Data Required to Support European Approval of CAP Indication for TYGACIL

... administered with caution in patients with known hypersensitivity to tetracycline class antibiotics -- Glycylcycline class antibiotics are structurally similar to tetracycline class antibiotics and may have similar adverse effects. Such effects ...

FDA Accepts Wyeth's Supplemental New Drug Application for Tygacil for the Treatment of Patients with Community-Acquired Pneumonia

... administered with caution in patients with known hypersensitivity to tetracycline class antibiotics. -- Glycylcycline class antibiotics are structurally similar to tetracycline class antibiotics and may have similar adverse effects. Such effects ...

Promising Data from Paratek Pharmaceuticals' MAR Inhibitor Program Presented in 'Late Breaker' Session at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

... C. difficile associated-diarrhea (CDAD). Outside the antibacterial therapeutic area, Paratek has also established an effort to exploit its novel tetracycline derivatives and their unique mechanism of action in selected inflammatory and neurodegenerative conditions. Paratek has an active chemical ...

Evaluating the Efficacy and Safety of Once-Daily Anti-Inflammatory Dose Doxycycline for the Treatment of Rosacea

... of rosacea targeted for treatment by anti- inflammatory dose doxycycline. The study concludes that "anti-inflammatory dose doxycycline is the only tetracycline agent proven to be effective for the treatment of rosacea in pivotal phase III clinical trials and exhibits a pharmacokinetic profile that separates ...
Tetracycline in Medical Dictionary

Antibiotic

... from HONselect: Antibiotic s Antibiotic Drug (such as penicillin, tetracycline or cephalosporin) that is able to kill or inhibit the growth of certain ... if a dipstick urine test does not show infection . Antibiotic s tetracycline is an oral antibiotic that has been used to treat acne for many years. ...

Antibiotics

... the stools . Antibiotics Antibiotic Drug (such as penicillin, tetracycline or cephalosporin) that is able to kill or inhibit the growth of certain ... ( bacteria ). Used to combat disease and infection . Antibiotics tetracycline is an oral antibiotic that has been used to treat acne for many years. ...

Anthrax

... bacteria or virus es to cause illness and spread fear). Smallpox and anthrax (a disease caused by the spores of a bacteria called ... tetracycline is also used to treat nongonococcal urethritis (due to Urea plasma ), Rocky mountain spotted fever , typhus , chancroid , cholera , ...

Breast milk

... and infections . Penicillin passes into breast milk in small amounts, but it is not usually harmful to a nursing baby. Doxycycline and tetracycline all pass into breast milk and may affect the bone and tooth development of a nursing baby. The virus can pass from mother to baby in ...

Brucellosis

... testing their new antibiotic against the bacteria that cause brucellosis and tularemia , as well as the bacteria that cause anthrax . tetracycline is also used to treat nongonococcal urethritis (due to Urea plasma ), Rocky mountain spotted fever , typhus , chancroid , cholera , ...

Chancroid

... those seen with sexually transmitted disease s ( STD ). Venereal warts , syphilis , genital herpes , chancroid , molluscum contagiosum , ... tetracycline is also used to treat nongonococcal urethritis (due to Urea plasma ), Rocky mountain spotted fever , typhus , chancroid , cholera , ...

Intestinal obstruction

... Fever and headache are other constitutional symptoms. Severe involvement of the rectal mucosa may cause intestinal obstruction or stricture. tetracycline is the drug of choice, although other antibiotics are effective. Intestinal Obstruction ( Bowel Obstruction) Intoxication with ...

Mycoplasma pneumonia

... pneumonia e, Streptococcus pneumonia e, Chlamydia l pneumonia e, and Haemophilus influenza e. However, bacteria that are resistant to tetracycline are common. Myco bacterial Culture of Suspected Non- Pulmonary Site of Pathology Mycoplasma Pneumonia Mycotic Arthritis (Fungal ...

Psittacosis

... ( psittacosis ) Search All of MedicineNet For: search help Printer-Friendly Format ... Psittacosis is treated with an antibiotic , usually tetracycline (Achromycin, Sumycin); doxycycline (Doxy, Vibramycin); or erythromycin (Eryc, Ilotycin). Oral medication is typically prescribed for at least 10-14 ...

Rabbit fever

... Deerfly fever ; Rabbit fever Treatment : The goal of treatment is to eliminate the infection with antibiotic therapy. Streptomycin and tetracycline are commonly used in this infection . (tlr´m) or rabbit fever , acute , infectious disease caused by Francisella tularensis (Pasteurella ...

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Tetracycline in Biological News

Gaining a better understanding of kidney diseases

... allows to selectively turn on and off the production of disease-typical proteins in renal tissue. It is activated simply by adding the antibiotic tetracycline to the animal food. To find out whether it is possible to study the development of kidney diseases in the genetically modified (transgenic) ...

Manure management reduces levels of antibiotics and antibiotic resistance genes

... more rapidly in the HIM-manure than in the LIM-manure. In the large-scale study, feedlot manure initially had higher concentrations of the several tetracycline antibiotics than the dairy manure. After four months of treatment, tet(W) and tet(O) decreased significantly in dairy manure, but two more months of ...

Tetracycline plus teeth equal gray smile

... public in order to hide their teeth darkened by tetracycline stains. Typically, invasive as well as costly ... during his discussion titled "Treating tetracycline Staining in the Adult Dentition" to be presented ... health technology, knowledge and treatment. tetracycline is a powerful antibiotic that kills a wide array ...

Novel live reporting system to track cells

... ferritin molecule to serve as a sort of gene "spy" by making genetic modifications to cells. This approach rendered ferritin sensitive to tetracycline (TET), a common antibiotic, so that when TET is present, the ferritin is "off" and when TET is absent, ferritin is "on." Tumor cells with modified ...
Tetracycline in Biological Technology

Neogen Develops Quickest Single Test for Beta-Lactams and Tetracyclines in Milk

... to simultaneously detect beta-lactam and tetracycline antibiotic residues in milk. Developed to ... in a single test. "As the use of both tetracycline and beta-lactam antibiotics for the management of ... rapid, easy tests to detect either beta-lactam or tetracycline antibiotics, or both at the same time, in the ...

Paratek Pharmaceuticals Completes $40 Million Private Placement to Finance Clinical Programs Including Oral Antibiotic to Combat MRSA and Other Infections

... is a broad spectrum antibiotic derived from the tetracycline class with oral and IV formulations that is being ... also developing other broad- and narrow-spectrum tetracycline antibiotics to treat hospital and community ... expertise. Outside of its tetracycline program, Paratek has also identified ...

Neogen Launches Quickest Test Available for Tetracyclines in Milk

... for the dairy industry to include the quickest test available for tetracycline residues in milk. The tetracyclines group of dairy antibiotics is used to ... mastitis in dairy herds in certain regions of the world, the concern over tetracycline drug residues in milk has grown," said Lon Bohannon, Neogen's president. ...

NewBridge Pharmaceuticals Announces Licensing of Pylera(R) for Middle East, Africa, Turkey & Caspian Region

... over the last ten years, is a patented 3-in-1 capsule therapy. Each Pylera (R) capsule contains bismuth subcitrate potassium, metronidazole and tetracycline hydrochloride. Pylera (R) is clinically proven to be as effective as the most widely prescribed therapeutic regimen for the eradication of ...

XL10-Gold Cells Supplied in New Single-Reaction Format

... endA1 supE44 thi-1 recA1 gyrA96 relA1 lac Hte [F proAB lacI q Z D M15 Tn10 (Tet r ) Amy Cam r ] The XL10-Gold strain is tetracycline and chloramphenicol resistant. REFERENCES Jerpseth, B., Callahan, M., and Greener, A. (1997) Strategies 10: 37-38. ...
Tetracycline in Biological Definition

Antibiotic resistance

... of blood poisoning in the UK in 1999, up from 4% in 1991. Half of all S. aureus infections in the US are resistant to penicillin, methicillin, tetracycline and erythromycin . This left vancomycin as the only effective agent available at the time. However, VRSA ( Vancomycin-resistant ...

Antibiotic resistance

... of blood poisoning in the UK in 1999, up from 4% in 1991. Half of all S. aureus infections in the US are resistant to penicillin, methicillin, tetracycline and erythromycin . This left vancomycin as the only effective agent available at the time. However, VRSA ( Vancomycin-resistant ...
Tetracycline in Biological Dictionary

Tetracycline

... tetracycline (INN) is a broad-spectrum polyketide antibiotic ... synthesis inhibitor. It is commonly ... tetracycline antibiotics are protein synthesis inhibitors, inhibiting the ... tetracycline inhibits cell growth by inhibiting ...

Tet resistance

... ... were tested by PCR for the presence of the tetracycline resistance genes tet (A) ... ... tetracycline resistance determinants by an inhibitor of the Tet (B) antiport protein.Antimicrob. ... tetracycline resistance mediated by hybrid Tet ....

Antibiotic

... substances have been reported. ... Online Medical Dictionary and glossary with medical definitions ... Another antibiotic , for example, is tetracycline (brand names: Achromycin and ... ANTIBIOTIC , ... More specifically, an antibiotic is a type of chemotherapeutic agent, that is, a ... ...
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