testosterone

A gene's first 'kiss' sets off that affair known as puberty

...the testes and ovaries to produce the sex hormones testosterone and estradiol, the culprits responsible for the physical changes and emotional baggage of male and female puberty, respectively. "We now have very good evidence that the GPR54 gene and its switch, the kisspeptin protein molecule produced by KiSS-1, ...

Scientists develop new color-coded test for protein folding

Every protein--from albumin to testosterone (Ed : testosterone isn't a protein, it's a steroid) --is folded into a unique, three-dimensional shape that allows it t...

Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells

... cases of prostate cancer depend on androgens like testosterone fortumor growth and cancer cell proliferation, sai...mon treatment for prostate cancer includeslimiting testosterone synthesis. Patients with mutated androgenreceptors may not respond to this therapy and according to ...

By creating molecular bridge, scientists change function of a protein

...eptor in a step-wise fashion, Zhao said. They used testosterone and progesterone to build the bridge. The receptor was gradually altered to accept one steroid, then another, until accepting the desired one -- corticosterone, a potent glucocoticoid. In total, Zhao and Chen did four rounds of random mutagenesis an...

Scientists find a maturity gene in fly

...lear hormone receptor." Hormones like estrogen and testosterone attach to these receptors, which in turn attach to genes in cell nuclei to switch the genes on or off. Nuclear hormone receptors are found in all animals, including flies and humans, and are linked to maturation. "So concluding that nuclear receptor...

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Sex Steroid Regulation of Vasopressin Levels Secreted by hNT Neurons*

...ected by Alzheimers due to the neuralconversion of testosterone to estrogen by the enzyme aromatase. 16 Thus, the ...and supraphysiological levels of estrogen, testosterone and dihydrotestosterone ( table 1 ). Cell culture media was collected at 6, 24 and 48 hours,...

Gender hormones may lend to social disorder therapies

... destinies. The receptors bind to hormones such as testosterone and estrogen and set in motion gender blueprints f...- in juvenile rats. Scientists were convinced that testosterone solely dictated the onset of such behavior. But researchers at the University of Wisconsin-Madison ...

testosterone at Biology Definition

Signal transduction

... hormones, with steroid hormones (for example, testosterone , progesterone and cortisol ) and derivatives of vitamin A and D among them. These hormones play a key role in the regulation of metabolism , organ function, developmental processes and cell differentiation . The key value for the signal s...

Klinefelter's syndrome

...toms can be treated in a number of ways, including testosterone treatment and other therapies. While the gender identity of people with XXY karyotype is usually male, the number of people with a female gender identity among them seems to be higher than could statistically be expected if those cases were indee...

Hormone

...primary sources. Examples of steroid hormones are testosterone and cortisol . Sterol hormones such as calcitrio...s aldosterone Sex steroids Androgens testosterone dehydroepiandrosterone (DHEA) dehydroepiandrosterone sulfate (DHEAS) androstenedione dihyd...

testosterone at Biology Dictionary

Seminiferous tubules

...called interstitial cells (Leydig cells ) where testosterone and other androgens are formed. [edit] Testicular size ... Full article >>> The walls of the seminiferous tubules consist of diploid spermatogonia , stem cell s that are the precursors of sperm . Spermatogonia divide by mit...

Karyotype

...veral different genetic alterations in pathways of testosterone synthesis and metabolism . Full article >>> (See Selectable marker .) Karyotype . All of the chromosomes in a cell or an individual organ ism, visible through a microsope during cell division . L Lag phase . Full article ...

Interstitial cells

...ous tubules of the vertebrate testis that secrete testosterone and other androgens , the male sex hormones . Full article >>> testosterone Male sex hormone secreted by the interstitial cells of the testes . Tethys Sea A shallow sea th...

Hormones

... collective name for male sex hormones including testosterone (andro = a man; gen = bear produce) Aneuploidy having an abnormal number of chromosomes (aneu = without; ploid = set of chromosomes ) ... Full article >>> any of a group of male sex hormones Source: Noland, George B. 1983. Gen...

Cells

...ous tubules of the vertebrate testis that secrete testosterone and other androgens , the male sex hormones . interstitial fluid ... Full article >>> Cells regulate the activity of genes in part by increasing or decreasing their rate of transcription . Full article >>> B cells ...

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testosterone at Medicine News

Gene linked to early puberty in girls

...ters.The gene called CYP1B1, acts by breaking down testosterone in the body of these girls and this starts off a cascade of hormones, which result in breast development.The scientists are now studying the effects of this gene on puberty in boys. Using the same yardstick they reason out that those with CYP1B1 gene...

New treatment for Osteoporosis

... This was done by discovering that oestrogen and testosterone can trigger more than one kind of signal in cells. It was known that when oestrogen binds to receptors in cells, it activates a signal that changes the gene expression. The team found that in bone cells, oestrogen can also trigger a signal preventing...

Low testosterone levels lead to eating disorders

The researchers suspect low testosterone levels in men suffering from eating disorders. Men who suffer from eating disorders can be affected more than women with the same problems, researchers say.// Eating disorders are associated with a weakening of the bones, which become dangerously ...

Memory problem? solve a crossword

...r trust in unproven cures such as melatonin, DHEA, testosterone and human growth hormone. These drugs and supplements may have long-term adverse effects.// Other strategies to keep the mind functioning, say experts, include lifelong learning and memory training, physical activity, meaningful work and social act...

Male contraceptive in trial

...of progesterone, then a pellet of the male hormone testosterone is placed under the skin in the abdomen.Study coordinator Professor David Chater from the Royal Kings Hospital in UK says the technique works by putting the testes to rest, while ensuring the male libido and male characteristics remain intact.// Pro...

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testosterone at Medicine Products

Testosterone EIA Reproductive Markers 020-DR-1559

...ortant androgen secreted into the blood. In males, testosterone is secretedprimarily by the Leydig cells of the testes; in females ca. 50% of circulating testosterone is derived fromperipheral conversion of androstenedione, ca. 25% from the ovary and ca. 25% from the...

3rd Generation Estradiol RIA Test

...vary [1]. In the ovary, estradiol is produced from testosterone [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. Th...

Estradiol EIA Test

...vary [1]. In the ovary, estradiol is produced from testosterone [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. Th...

Estradiol RIA Test

...vary [1]. In the ovary, estradiol is produced from testosterone [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. Th...

Estradiol, Ultra-Sensitive RIA Test

...vary [1]. In the ovary, estradiol is produced from testosterone [1,2], and from estrone, a less potent estrogen derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. Th...

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testosterone at Medicine Technology

BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine

...., BioSante's licensee, andLibiGel(R) (transdermal testosterone gel) in Phase III developmentby BioSante for the t...tion (FSD).Also in development is Bio-T-Gel(TM), a testosterone gel for malehypogonadism, and an oral contraceptive using BioSante patentedtechnology. The current m...

Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference

...hysicians.Auxilium markets Testim(R) 1%, a topical testosterone gel, for thetreatment of hypogonadism through its approximately 190-personsales and marketing team. Auxilium has four projects in clinicaldevelopment. AA4500, an injectable collagenase enzyme, is in phaseIII of development for the treatment of Dupuyt...

Peer Reviewed Journal Article Indicates Repros' Proellex Exhibits Potential for New Approach to the Treatment and Prevention of Breast Cancer

...clinical development, is designed to restorenormal testosterone production by the testes and has recentlycompleted...pivotal Phase 3 clinical trial forthe treatment of testosterone deficiency in men due to secondaryhypogonadism. According to industry sources, approximately 13milli...

New Poll Shows Men, Women Incorrectly Blame Symptoms of Low Testosterone on Normal Aging

... women believe their malepartner's symptoms of low testosterone negatively impact theirrelationship, treatment of ... quality ofthe relationship. Low testosterone, or testosterone deficiency associated withhypogonadism, is a medical condition caused by disease or damage tothe tes...

New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy

...., BioSante's licensee, andLibiGel(R) (transdermal testosterone gel) in Phase III developmentby BioSante for the t...tion (FSD).Also in development is Bio-T-Gel(TM), a testosterone gel for malehypogonadism, and an oral contraceptive using BioSante patentedtechnology. The current m...

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testosterone at Medicine Dictionary

Virilization

... tumor whose sells secrete a male sex hormone ( testosterone ) causing virilization in women. [ Med Help International ] [ Search ] [ Ask the Doctor Forums ] ... Full article >>> polycystic ovaries stops menstruating, menstruates erratically, or may not have ever menstruated. She will gain w...

Undescended testicle

... they produce sperm and the male sex hormone , testosterone , from puberty through adulthood. Full article ...ilk , meat, and/or coffee; use of male hormone ( testosterone ) in treatment of impotence ; vasectomy ; ... Full article >>> Because testicula...

Trauma

...#62;>> Scientists also found that while testosterone levels may significantly decrease after surgery , trauma or illness, the figures still showed an increased risk of death when these factors were taken into account. Full article >>> STOMATITIS : Inflammation of the mucous mem...

Tic

...uggests that exposure to male hormone s, such as testosterone , during fetal development may play a role in the later development of TD. Full article >>> The first symptom of Tourette syndrome is usually a facial tic , such as eye blinking. As many as 1 in 200 children develops tic s ...

Testosterone

... Therapy to Treat ED - Erectile dysfunction (ED): testosterone replacement therapy for sexual health Source:We...sfully for years to treat men with abnormally low testosterone levels - a medical condition called male hypogonadism . Full article >>> Testoster...

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