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Testes in Medical News

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive

... first time a specific "niche factor" in the mouse testes called colony stimulating factor 1, Csf1, that ... growth factor is the Leydig cell located in the testes and stimulated by the pituitary gland to supply ... and production of spermatozoa in the testes of adult males, whether man or mouse. The SSCs' ...

Testes stem cell can change into other body tissues, Stanford/UCSF study shows

... one and the same. According to the study, the testes stem cells have different patterns of gene ... authors of the study. The stem cells from the testes seem to hover in a gray area between true ... suggest that the stem cells isolated from male testes have some, but not all the characteristics of ...

Penn Veterinary Medicine report new strategy to create genetically modified animals

... from experimentally induced cryptorchid donor testes that were then exposed in vitro to AAV vectors ... resulting in colonization of the recipient testes by transgenic donor cells. When researchers ... Transgenic germ cells colonized recipient testes and produced transgenic sperm. When semen was ...

Stem Cells From Testes Produce Wide Range of Tissue Types

... reprogrammed adult stem cells from the testes of male mice into a wide variety of cell types, ... cells. If the same can be done with adult testes stem cells from humans, they may offer a source ... journal Nature . Only a small subset of adult testes cells have the ability to develop into multiple ...

Stem cells derived from adult testes produce wide range of tissue types

... in reprogramming adult stem cells from the testes of male mice into functional blood vessels and ... to develop into multiple cell types -- from adult testes cells. But only a small subset of cells from the testes has the potential to become pluripotent, and ...

Researchers clone key sperm-binding proteins

... and rodents. According to Dr.Manjunath and his team, these species produce small amounts of BSPs only in the epididymis, a duct that connects the testes to the urethra. "For a few years, we were looking in the wrong place," says Dr. Manjunath. "In addition, the minute quantities of BSP produced in ...

Marijuana Linked to Aggressive Testicular Cancer

... or more external factors, including a simultaneous and comparable rise in the use of marijuana. Along those lines, the researchers noted that the testes could be particularly vulnerable to the effects of marijuana, given that the organ -- along with the brain, heart, uterus and spleen -- carries ...

Marijuana use linked to increased risk of testicular cancer

... Sciences Division at the Hutchinson Center. Established risk factors for testicular cancer include a family history of the disease, undescended testes and abnormal testicular development. The disease is thought to begin in the womb, when some fetal germ cells (those that eventually make sperm in ...

The Obama Cancer Plan Should Prioritize Prevention, Says Cancer Prevention Coalition

... statistics. These show increases of 45% for thyroid cancer, 18% for malignant melanoma, 18% for kidney cancer, 10% for childhood cancers, and 4% for testes cancer. Disturbingly, the NCI has still failed to develop, let alone publicize, any listing or registry of avoidable exposures to a wide range ...

Living with females extends the reproductive life of the male mouse, says Penn veterinary researcher

... niche in the mature adult male testis. In subsequent studies, Brinster determined that when the SSCs of young males were transferred into new young testes every three months, the SSCs survived for more than three years, a greater than 50 percent increase in life of the stem cell. Therefore, in old ...

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Testes in Medical Technology

Repros' Proellex Shows Statistically Significant Improvement in Primary Endpoint in Phase 2 Trial in the Treatment of Uterine Fibroids

... U.S. and Canada. Androxal(TM), the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes and is being tested in a non-pivotal U.S. Phase 3 clinical trial for the treatment of testosterone deficiency in men due to secondary hypogonadism. ...

Repros' Androxal Shows Highly Statistically Significant Positive Effects in Men with Secondary Hypogonadism

... the U.S. and Canada. Androxal, the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes and has completed a six month U.S. Phase 3 clinical trial for the treatment of testosterone deficiency in men due to secondary hypogonadism. ...

Repros Reports That Proellex Has Demonstrated Superior Efficacy and Safety in Endometriosis When Compared to Standard of Drug Care

... and Canada. Androxal(TM), the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes in men and has recently completed a six-month U.S. non-pivotal Phase 3 clinical trial for the treatment of testosterone deficiency due to ...

Peer Reviewed Journal Article Indicates Repros' Proellex Exhibits Potential for New Approach to the Treatment and Prevention of Breast Cancer

... and Canada. Androxal(TM), the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes and has recently completed a six-month U.S. non-pivotal Phase 3 clinical trial for the treatment of testosterone deficiency in men due to ...
Testes in Medical Products

Progesterone EIA Test

Description:... is a steroid produced by the adrenal cortex, the corpus luteum, the testes and the placenta. As with other steroids, progesterone is synthesized from ... steps [1,2]. Progesterone produced by the adrenal cortex and testes is almost immediately shunted into other steroidogenic pathways, with only ...
Company:Diagnostic Systems Laboratories, Inc.

Progesterone RIA Test

Description:... is a steroid produced by the adrenal cortex, the corpus luteum, the testes and the placenta. As with other steroids, progesterone is synthesized from ... steps [1,2]. Progesterone produced by the adrenal cortex and testes is almost immediately shunted into other steroidogenic pathways, with only ...
Company:Diagnostic Systems Laboratories, Inc.

Testosterone RIA Test

Description:... a C19 steroid, is one of the most potent naturally secreted androgens [1]. In postpubertal males, testosterone is secreted primarily by the testes with only a small amount derived from peripheral conversion of androstenedione [2]. In adult women, it has been estimated that over 50% of serum ...
Company:Diagnostic Systems Laboratories, Inc.

Testosterone EIA Test

Description:... a C19 steroid, is one of the most potent naturally secreted androgens [1]. In postpubertal males, testosterone is secreted primarily by the testes with only a small amount derived from peripheral conversion of androstenedione [2]. In adult women, it has been estimated that over 50% of serum ...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol, Ultra-Sensitive RIA Test

Description:... derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of ...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol RIA Test

Description:... derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of ...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol EIA Test

Description:... derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of ...
Company:Diagnostic Systems Laboratories, Inc.

3rd Generation Estradiol RIA Test

Description:... derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of ...
Company:Diagnostic Systems Laboratories, Inc.

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Testes in Medical Dictionary

Cryptorchidism

... Cryptorchidism ; Empty scrotum - undescended testes ; Scrotum - empty (undescended testes ); Monorchism; Vanished testes - undescended Receive our free newsletter or ...

Hypogonadism

... used to differentiate hypogonadism ( ovary or testes ) into primary hypogonadism (problem is with the ovary or testes ) or secondary hypogonadism (problem is with ... or the hypothalamus ). Anorchia (absense of testes , or lack of function of ...

Precocious puberty

... signs of puberty (development of breasts , testes , pubic and underarm hair , body odor, menstrual ... premenstrual syndrome . Anorchia (absense of testes , or lack of function of testes ) Hypogonadism Klinefelter's syndrome ...

Scrotum

... scrotum is the sac (pouch) that contains the testes , blood vessels, and part of the sperm atic ... Scrotum : The sac of skin that contains the testes . Semen : The fluid, containing sperm , which ... be 4 degrees cooler than body temperate for the testes to produce the required quality and quantity of ...

Testes

... testes Definition: The testes are two egg-shaped male reproductive organ s ... and the male hormone , testosterone . testes Powered by: This information is provided by an ...

Gland

... ad renal , islands of Langerhans in the pancreas , and the gonad s ( testes and ovaries). Northern En gland 'worst for binge drinking' 7 August ... s Breast Disease s Gonad al Disorders - Disease of the ovaries and testes of any etiology . Endocrine gland s Pelvic laparoscopy Female ...

Gonad

... Alternate Names : Gonad s - Male, Testicles, Testis Definition The testes are two egg-shaped male reproductive organ s located in the scrotum . ... injection s ... Gonad al Disorders - Disease of the ovaries and testes of any etiology . Para thyroid Diseases ... Gonad otropina corinica ...

Ovarian hypofunction

... hormone production. Jump to another section ... Anorchia (absense of testes , or lack of function of testes ) Hypogonadism Klinefelter's syndrome Menopause Ovarian failure ...

Renal

... by drugs. Examples include macrophage s, lymphocyte s, the brain, and testes . Renal ( kidney ) causes of vitamin D malabsorption should be ... s Breast Disease s Gonad al Disorders - Disease of the ovaries and testes of any etiology . ad renal glands Located on top of the kidney s, ...

Sperm

... [Kellogg] Testicular Atrophy ... Sperm Definition: The testes are two egg-shaped male reproductive organ s located in the scrotum . ... that you are HIV -positive. During sexual activity, sperm from the testes enters the urethra near the opening of the bladder . Normally, a ...

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Testes in Biological News

Human adult testes cells can become embryonic-like

... Center have extracted stem/progenitor cells from testes and have converted them back into pluripotent ... are among the first scientists to show that human testes stem cells can become embryonic stem-like cells, ... a new and simpler method to isolate the testes stem/progenitor cells than has not been seen in ...

Female embryonic sexual development driven by universal factor

... Y chromosome) that appeared to be essential for testes formation. But when researchers discovered some rare cases of individuals who developed testes even though they had two X chromosomes and no Y ... called the "Z" hypothesis, which proposed that testes development was actually the default pathway. ...

Penn Veterinary Medicine report new strategy to create genetically-modified animals

... from experimentally induced cryptorchid donor testes that were then exposed in vitro to AAV vectors ... resulting in colonization of the recipient testes by transgenic donor cells. When researchers ... Transgenic germ cells colonized recipient testes and produced transgenic sperm. When semen was ...

October 2008 Biology of Reproduction highlights

... Because the CKO mice exhibited transient fertility, an elegant reporter strategy was used to demonstrate that elongated spermatids present in the CKO testes did express the Cre recombinase; therefore, it is likely that differentiation to this stage can occur in the absence of DICER1. Nonetheless, Dicer1 ...

New study points to agriculture in frog sexual abnormalities

... have found that toads in suburban areas are less likely to suffer from reproductive system abnormalities than toads near farms where some had both testes and ovaries. "As you increase agriculture," said Lou Guillette, a distinguished professor of zoology, "you have an increasing number of ...

Eliminating germline lengthens fly lifespan, Brown study shows

... team found a possible explanation for the paradox. In reaction to the flies brains boosting insulin production, the insects gonads their ovaries or testes produce a protein that acts like a sponge, binding to the insulin and blocking its signals throughout the body. So the flies respond as if there is ...

Armed beetles find a mate, whatever their size

... sites with the big males, and attempt sneaky matings with females behind the bigger males backs. Whats more, these males have relatively larger testes and produce sperm that is more competitive than the bigger males. The L. japonicus beetles have ensured that, through their size-determined mating ...

Safeway Inc. and PCF to fund landmark prostate cancer research collaboration

... begins in the testes, which are a few degrees cooler than the rest of the body. The structural machinery of cancer cells spreading outside the testes may be altered by the higher body temperatures, making them more susceptible to standard chemotherapy treatments than other cancer types. While ...

Vaginal reconstruction not needed for most inter-sex females, Hopkins study shows

... Women with complete androgen insensitivity are born with relatively shallow vaginas that may or may not require surgical repair and with undescended testes that do require removal. Vaginal surgery, if needed or wanted, should be done after puberty, when physical development is complete and a girl or ...

Injection may prevent infertility in men receiving cancer chemotherapy

... It may be possible to protect the testes of cancer patients against the loss of fertility ... After 30 days they were euthanized and their testes examined and weighed. The researchers found ... weight loss. "Tissue analysis of the testes of Taxol-injected mice showed severe atrophy and ...

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Testes in Biological Technology

New Report Just Published: World Prostate Cancer Therapeutics Market Report

... by Cancer Type in the US, 2000- 2004 (includes corresponding Graph/Chart) II-18 Prostate - Structure II-18 Pituitary Gland II-19 testes II-19 Prostate Cancer - A Primer II-20 Key Facts to Gaze at II-20 Table 13: Lifetime Probability of Developing Cancer (in Men) by ...

RT-PCR Primers for the Study of Apoptosis

... library generated a PCR product larger in size than expected (lane 4). This may be a spliced version of Fas antigen found in testes or an artifact. Again, the amplification of the rat Fas antigen gene is specific. No band appeared on the control lanes with mouse and ...
Testes in Biological Definition

Spermatogenesis

... or genesis, of sperm cells, which occurs in the male gonads or testes . Sperm cells develop initially from germ stem cells known as ... is maintained. Spermatozoa are produced in seminiferous tubules in the testes . They start off as spermatogonia , undergoing mitosis becoming a type A ...

Klinefelter's syndrome

... is characterised by gynecomastia (enlarged breasts), a rounded body type with abnormal body proportions, sparse facial and body hair , small testes , and an inability to produce sperm . Most XXY males have some degree of language impairment as well. The syndrome is associated with an increased ...

Semen

... 5 References 6 External links Composition Around 200 million to 500 million spermatozoa (or 'sperm', for short), produced in the testes , are released per ejaculation. However, they make up only about 2–5% of the volume of semen. The bulk of the semen is composed of seminal ...

Sperm

... by a minimum of cytoplasm. Sperm production Main article: Spermatogenesis Sperm are produced in the seminiferous tubules of the testes in a process called spermatogenesis. Round cells called spermatogonia divide and differentiate eventually to become sperm. During sexual ...
Testes in Biological Dictionary

Testes

... 4.2 Diseases and conditions that affect the testes . 4.3 Effects of exogenous hormones ... Lymphatic drainage of the testes follows the testicular arteries back to the ...... ... 4.2 Diseases and conditions that affect the testes . 4.3 Effects of exogenous hormones ... ...

Gonads

... gonad is the organ that makes gametes. The gonads in males are the testes and the gonads in females are the ovaries. The product, gametes, are ... a part of the development of reproductive system and ultimately forms the testes Gonads are the true sex organs, generating reproductive gametes ...

Urethra

... ... The urinary tract is made up of the kidneys, the ureters, the bladder, and the urethra . The male reproductive tract includes the penis, testes (testicles). The ... ... of cancer of the urethra . Anterior urethral cancer. Posterior ... How cancer of the urethra is treated. ...

Spermatids

... their permissiveness in ... Round spermatids , characterized by their small size as well as a centrally ... ... spermatids was observed in the testes from rats in which ... Key words: Pachytene spermatids , round spermatids , developing rat testis, spermatogenic arrest ... Classification of ...

Seminiferous tubules

... reproductive function ( in animal reproductive system: Testes; In anurans, amniotes (reptiles, birds, and mammals), and even some teleosts, testes are composed largely of seminiferous tubules—coiled tubes, the walls of which contain cells ... At the forefront of medicine, Gene ...

Scrotum

... penis and anus. In humans and some other mammals, the base of ... scrotum n. , pl. -ta or -tums . The external sac of skin enclosing the testes in ... The skin of the scrotum is exceptionally thin and beset with thinly ... The cause of an acute scrotum can usually be established based ...

Ovary

... ovum-producing reproductive organ, often found in pairs as part of the vertebrate female reproductive system. Ovaries in females are homologous to testes in males, in that they are both gonads and ... In the flowering plants, an ovary is a part of the female reproductive organ of the ...

Inverted Repeats

... - Inverted Repeats Finder. Please ... " Inverted Repeat Structure of the Human Genome: ... Highly Homologous Inverted Repeats That Contain testes Genes" ... Inverted Repeats Database (IRDB) is a public repository of information on ... These currently include, the Inverted Repeats ...

Interstitial cells

... the free encyclopedia. Jump to: navigation, search. Interstitial cells may refer to: Leydig cells , cells present in the male testes ... interstitial adj. Relating to, occurring in, or affecting interstices. Anatomy. Relating to or situated ... and surrounds the cells of ...

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