Multivitamins Might Prolong Life
... corresponds to about 9.8 years less age-related telomere
shortening, the researchers noted.
Vitamins C ... Chen said.
But, whether the vitamins preserved telomere
length or actually lengthened life is not clear, ... a healthy lifestyle," he said. "Although shorter telomere
length has been linked to higher mortality and ...
RevGenetics Releases Its New Science-Based Telomere Health Supplement Formulation for DNA and Chromosome Health
... helps slow and repair some of the natural telomere
DNA shortening that happens as we age
MIAMI, ... update and release of its latest science-based telomere
health supplements , Astral Fruit. To ... at a recent study entitled: "Proteins induced by telomere
dysfunction and DNA damage represent biomarkers ...
First sister study results reinforce the importance of healthy living
... that cap the ends of a person's chromosomes. telomere
length is one of the many measures being looked ... women who were obese for a long time had reduced telomere
length. The researchers looked at the ... measures of current and past body size and telomere
length in 647 women enrolled in the Sister Study. ...
Enhanced skin cancer risk linked to defects in cellular aging controls
... (DMM), dmm.biologists.org , describes how telomere
dysfunction in skin cells can lead to increased ... the molecular mechanisms underlying skin cell telomere
dysfunction using a mouse model of Xeroderma ...
This study establishes a link between telomere
dysfunction, cancer progression and the ...
The 2009 Leibniz Prize: Eleven new scientific discoverers
... division. Rudolph has studied this process of telomere
shortening and its effects in numerous ... is in the enzyme telomerase, which inhibits the telomere
shortening, thus allowing cells to divide more ... models and mutants, Rudolph was able to show that telomere
shortening ultimately leads to a shorter lifespan ...
Science Fiction Has Become Reality with Remarkable Anti-Aging Treatment Breakthrough - Turning Back the Biological Clock in Aging
... is a revolutionary technology that is based on telomere
Telomeres are part of your DNA. They are ... an opportunity to slow
or potentially reverse telomere
shortening-hence technically making ... 64, recipient of
The emerging science of telomere
biology is changing the way science
and society ...
Sedentary Lifestyle Accelerates Aging
Overall, the study participants had an average telomere
loss of 21 nucleotides (structural units) per ... active.
"Such a relationship between leukocyte telomere
length and physical activity remained significant ... wrote.
"The mean difference in leukocyte telomere
length between the most active [who performed an ...
Mayo Clinic study points to a possible biomarker for colon cancer in people 50 and under
... telomeres raises the possibility of one day using telomere
length as a biomarker of cancer or an early ... between colon cancer patients and increased telomere
shortening is exciting because, if validated, it ... treatment strategies. For example, we know that telomere
length can be repaired, so we want to look ...
Advances in drug screening: building a better haystack for the needles of tomorrow
... of molecular compounds for the ability to disrupt telomere
maintenance. Through their screening process, the ... that keep the DNA from fraying at the ends. The telomere
consists of a short repeated segment of six DNA ... below a critical threshold. In cancers, the telomere
structures are maintained but they require ...
New telomere discovery could help explain why cancer cells never stop dividing
... may provide a new avenue of attack for stopping telomere
renewal in cancer cells.
Inside the cell ... from getting scrambled when cells divide. The telomere
is like a cellular clock, because every time a cell divides, the telomere
shortens. After a cell has grown and divided a ...
Telomere in Medical Technology
Telomere in Medical Dictionary
... including genomic instability, cell cycle checkpoint defects and predisposition to cancer and aging , which are believed to be related to telomere
Telomere in Biological News
Researchers use chemical from medicinal plants to fight HIV
... because a part of their chromosomes known as a telomere
becomes progressively shorter with cell division. ... therapy, can prevent or slow this progressive telomere
shortening, which could make it a key weapon in ... .
is a region at the end of every cell chromosome ...
When cells go bad
... the first to show in animals that losing just one telomere
the end of a chromosome can lead to many ...
"The essential point is that loss of a single telomere
may be a primary event that puts a cell on the ... biology, found how fruit fly cells with a missing telomere
sometimes avoid suicide and instead continue to ...
Baumann lab identifies elusive telomere RNA subunit in single cell model
... for new anti-cancer drugs. A correlation between telomere
length and a variety of diseases has further ... on the sometimes surprising correlations between telomere
shortening and stress, smoking, obesity, and a ... in a variety of simple model organisms, but telomere
maintenance turned out to be quite different in ...
Could vitamin D, a key milk nutrient, affect how you age?
... stress. Using a genetic marker called leukocyte telomere
length (LTL), they found those with the highest ... lower levels of inflammation and body stress. The telomere
difference between those with the highest and ... there are several lifestyle factors that affect telomere
length (obesity, smoking and lack of physical ...
Peter Baumann named Howard Hughes Medical Institute Early Career Scientist
... degenerative diseases. On the other hand, telomerase, a protein central to telomere
elongation, is activated in most cancer cells and is considered a promising target for anticancer drugs. By understanding how telomere
lengthening is regulated and how telomeres are prevented from becoming too ...
UT Southwestern researchers identify gene linked to inherited form of fatal lung disease
... almost 15 percent of those with familial IPF. Up to 40 percent have short telomere
lengths and evidence of telomerase dysfunction.
"But we were still left ... Dr. Garcia said. "What about the rest of the families that have normal telomere
lengths? What was causing their lung disease?"
In the current study, ....
Landmark study opens door to new cancer, aging treatments
"It's extremely exciting," Skordalakes says. "For the first time, we can see how telomerase assembles at the end of chromosomes to initiate telomere
Skordalakes plans to further study TERT and search for new telomerase inhibitors that could become cancer ...
UCLA study identifies mechanism behind mind-body connection
... heart disease and aging. Previous studies show that an enzyme within the cell, called telomerase, keeps immune cells young by preserving their telomere
length and ability to continue dividing.
UCLA scientists found that the stress hormone cortisol suppresses immune cells' ability to ...
Osteoarthritis may be sign of faster 'biological ageing'
... the findings showed that white cell telomere
lengths were associated with chronological age. ... the 160 people with hand osteoarthritis, the telomere
length was significantly shorter than among those ... osteoarthritis were over 50, and the amount of telomere
shortening was equivalent to that accrued over 11 ...
A little telomerase isn't enough
... animals turns out to be the animal's inherited telomere
length, not the status of the telomerase gene, ...
"We know it only takes one critically short telomere
to make a cell die, so it's clear that the more ... lab reported the role of the critically short telomere
The usual treatment for people with ...
Telomere in Biological Technology
Former Telomolecular CEO Clarifies SEC Settlement
... particularly diseases related to chromosomal telomere
shortening. The Company worked with a number of ... to human cells and observe significant signs of telomere
regeneration that was not observed when ... diseases of aging might respond positively to telomere
elongation. The company had also made advances in ...
Ten Top Latin American Scientists Named 2009 Pew Fellows in the Biomedical Sciences
... Luis Francisco Zirnberger Batista, Ph.D.
Laboratory of Steven Artandi, M.D., Ph.D.
complex and genetic disease
Veronica Eisner, Ph.D.
Laboratory of Gyorgy ...
Gemin X Pharmaceuticals Selects and Deploys Clinical Force CTMS
... candidates obatoclax (GX15-070), an innovative pan Bcl-2 inhibitor, and GMX1777, a novel inhibitor of NAD+ synthesis, and preclinical studies for its telomere
Capping and SMAC Mimetic programs. Potential treatment indications for the full scope of pipeline programs span a broad range of hematological and ...
Telomere in Biological Dictionary
... A telomere
is a region of repetitive DNA at the ends of ... themselves genes, but neither are they ... The telomere
theory ... Thus, telomere
erosion and Hayflick limits could account for ...
... specific DNA sequence repeats to the 3' end of DNA strands in the telomere
regions, which are found at the ends of eukaryotic chromosomes. The ... of the cellular aging ... Though telomerase is required to maintain telomere
length, it is inactive in ... Since such cells still lack telomerase , ...