Navigation Links
Surfactant in Medical News

Protein may be strongest indicator of rare lung disease, study shows

... (IPF). Researchers say the proteinSerum surfactant protein Ais superior to other IPF predictors and ... the June 4 edition of the journal Chest . surfactant proteins are lipoproteins that allow the lungs to ... MD. Kinder and colleagues report that Serum surfactant protein A is the strongest predictor of a ...

New treatment could reduce chronic lung disease in premature babies

... physicians say. The problem is that while surfactant keeps the tiny air sacs inside the lungs from ... Traditionally, babies are given the surfactant through an endotracheal tube and left on the ... studying 60 premature babies. Thirty will receive surfactant the traditional way and another 30 will receive ...

Pollin Pediatric Research Prize awarded for discovery of lifesaving treatment of RDS

... us to understand the essential role of pulmonary surfactant in normal lung function, a discovery that led to ... of NewYork-Presbyterian Hospital. Replacement surfactant is now a standard therapy for premature infants ... Dr. John A. Clements and Discovery of Lung surfactant After graduating in 1947 from Cornell ...

The microbial hydrocarbon diet

... a temperature of 30 Celsius are optimal for the microbe to produce the main degradation enzyme. They also point out that adding a small amount of a surfactant material, rhamnolipid, can also stimulate enzyme production and improve degradation efficiency. ...

More 'Extreme' Preemies Surviving

... which are drugs that delay or stop labor, corticosteroids or both appeared to help lower the odds of death. So did treatment soon after birth with surfactant -- a fluid produced shortly before birth that prevents the lungs from filling with water. Birth at an "advanced care" hospital was also associated ...

New Hair Product Line Addresses Common Scalp Conditions of Teens and Tweens

... water and perfumes. She went on to work with a chemist in Indiana to formulate a shampoo and conditioner that would use a deodorizer mixed with the surfactant to address teenage scalp conditions and combat head smell. Tying in the natural association between teens and texting , Totally Texty became a ...

Gene Mutation Tied to Inherited Fatal Lung Disease

... The findings were published in the January issue of The American Journal of Human Genetics . The SFTPA2 gene normally produces the surfactant protein A2 in the fluid of the lungs, and it helps protect the organ from invading pathogens. In the study, in which University of Texas ...

New topical approach to treating nail fungus circumvents problems with current therapy

... anti-infective activity to NB-002's novel technology platform. The lotion is composed of an oil-in-water emulsion and a commonly used antimicrobial surfactant that are mixed at high speeds to nanosize the particles and infuse them with high levels of potential energy. The resulting nanodroplets easily ...

Topical treatment for cold sores achieves efficacy of oral drugs; represents paradigm shift

... anti-infective activity to NB-001's novel technology platform. The lotion is composed of an oil-in-water emulsion and a commonly used antimicrobial surfactant that are mixed at high speeds to nanosize the particles and infuse them with high levels of potential energy. The resulting nanodroplets easily ...

Children More Vulnerable to Harmful Effects of Lead at Age 6 Than as Toddlers, Says New Study

... National Institutes of Health. It has an established tradition of research excellence, with discoveries including the Sabin oral polio vaccine, the surfactant preparation that saves the lives of thousands of premature infants each year, and a rotavirus vaccine that saves the lives of hundreds of thousands ...

More>>

Surfactant in Medical Technology

PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans

... 10mg CsA/2.5mL for inhalation delivery via a customized Investigational eFlow Nebulizer System. The L-CsA formulation is based on an artificial lung surfactant carrier. It is free of any irritating organic solvents and consists of unilamellar liposomes of about 100nm. The unilamellar liposomes are obtained ...

Inhaled Nitric Oxide Data Presented at European Academy of Pediatrics Meeting

... III clinical trial, examined 800, pre-term infants ranging in gestational age from 24 weeks to 28 weeks, 6 days. All patients required the use of surfactant within 24 hours of birth or the use of CPAP, or continuous positive airway pressure, to maintain an oxygen saturation value of greater than or equal ...

New Patent Awarded for Antigen-Sparing Vaccines that Elicit Robust Immunity

... The newly awarded patent covers the methods and compositions of formulating nanoemulsion vaccines, a unique coupling of oil, water, and antimicrobial surfactant together with antigens from specific pathogens. Studies in animals demonstrate these vaccines easily penetrate the mucous membrane, where dendritic ...

Large Controlled Trial of Widely Used Mood Stabilizers Demonstrates Efficacy in Pediatric Bipolar Disorder

... National Institutes of Health. It has an established tradition of research excellence, with discoveries including the Sabin oral polio vaccine, the surfactant preparation that saves the lives of thousands of premature infants each year, and a rotavirus vaccine that saves the lives of hundreds of thousands ...

Preterm Infants with Respiratory Distress Syndrome: Incidence Rates of Death when Treated with Surfactant Replacement Therapies

... long needed a robust basis upon which to choose surfactant therapies for premature babies suffering form ... RDS is a condition caused by a deficit in lung surfactant in infants who are born prematurely. Surfactant, ... should carefully weigh their choice of surfactant therapy in their clinical practice." The study ...

Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric Academic Societies' Annual Meeting

... pre-clinical studies using aerosolized KL-4 surfactant were also presented to the medical community for the first time. In these studies, KL-4 surfactant was aerosolized to compare Chrysalis' novel, ... system that combines precision-engineered KL-4 surfactant technology with the capillary aerosol ...

Discovery's KL-4 Surfactant Technology Demonstrates Novel Anti-Inflammatory Properties

... Discovery's KL-4 surfactant Technology Demonstrates Novel Anti-Inflammatory ... animal-derived surfactant and the most prescribed surfactant in the United States. * Surfaxin (KL-4 ... and preserving pulmonary function." About KL-4 surfactant ...

Surfaxin (Lucinactant) Long-Term Survival Advantage vs. Comparators Published in Pediatrics

... they suggest that a next-generation surfactant therapy, such as Surfaxin, may save more babies' ... trials is unique given direct comparisons between surfactant products. The data set from this recently ... Inc. is a biotechnology company developing surfactant Replacement Therapies (SRT) for ...

Targanta Reports Improved Ability of Oritavancin to Stop Bacteria Growth In Vitro Compared With Other Glycopeptide Antibiotics

... effect of ORI, DAP and CTX against S. aureus when a pulmonary surfactant preparation (up to 5%, by volume) was added. Results showed a 2- ... for DAP MIC and no shift for CTX MIC. Researchers concluded that surfactant only minimally affected the antibacterial activity of ORI when ...

More>>

Surfactant in Medical Products

Bausch & Lomb Concentrated Cleaner

Description:... Bausch & Lomb concentrated cleaner is a sterile, concentrated homogeneous surfactant solution containing alkyl ether sulfate, ethoxylated alkyl phenol, tri-quaternary cocoa-based phospholipid and silica gel as cleaning ....
Company:Bausch & Lomb, Inc.

Opti-One Multi-Purpose Solution

Description:... Opti-One multi-purpose solution with citrate protein removal and advanced surfactant ....
Company:Alcon Laboratories
Surfactant in Medical Definition

Proteopathy

... Cutaneous lichen amyloidosis Keratins Corneal lactoferrin amyloidosis Lactoferrin Pulmonary alveolar proteinosis surfactant protein C (SP-C) Critical illness myopathy (CIM) Hyperproteolytic state of myosin ubiquitination References ^ Walker ...
Surfactant in Medical Dictionary

Surfactant

... surfactant : A fluid secreted by the cells of the alveoli ... the surface tension of pulmonary fluids; surfactant contributes to the elastic properties of pulmonary tissue . surfactant is normally released into the lung tissue s ...

Hyaline Membrane Disease

... in newborn infants caused by a deficiency of a molecule called surfactant . (These membrane s are very prominent in premature infant s who ... (poractant alfa) intra tracheal suspension A porcine-derived lung surfactant for the treatment of respiratory di stress syndrome ( hyaline ...

Asphyxia

... to lack of oxygen to the brain) and trauma , but in a study of 45, ... perinatal asphyxia cold stress (a condition that suppresses surfactant production) perinatal infection multi ple birth s ( multi ple birth babies are often premature) ... Unborn babies whose mothers are ...

IRDS

... IRDS is caused by a lack, in the immature lung, of a surfactant agent; the substance, a mixture of lipid s and protein s, ... IRDS ( Infant Respiratory Distress Syndrome ) Iritis ( Uveitis ) Iron ...

Meconium

... the amniotic fluid to light, which can falsely lower bilirubin levels. Blood or meconium in the ... Surfaxin (lucinactant) Pulmonary surfactant in clinical trials for the treatment of acute respiratory di stress syndrome ( ARDS ) in adults, respiratory di stress syndrome ...

Meconium aspiration

... much) and air leaks. Air leaks often occur in the first 24 to 36 hours when lung disease is at its peak. Surfaxin (lucinactant) Pulmonary surfactant in clinical trials for the treatment of acute respiratory di stress syndrome ( ARDS ) in adults, respiratory di stress syndrome ...

More>>

Surfactant in Biological News

First tri-continuous mesoporous Silica complex structure developed in Singapore

... tri-continuous mesoporous material using a unique surfactant template. This completely new porous structure ... synthesized via self-assembly of silica around surfactant templates. IBN researchers successfully ... structure by using a specially designed surfactant template, N,N-dimethyl-L-phenylalanine. ...

Inherited genetic cause, possible treatment found for complex lung disorder

... the critical role of the gene CSF2RA to balanced surfactant levels in the lung," Dr. Trapnell said. "These ... with PAP, including elevated blood levels of surfactant protein and an accumulation of surfactant in her lungs. Researchers found a mutation of ...

American Chemical Society's Weekly PressPac -- Dec. 3, 2008

... by scientists to find one. Past research pointed to a prime candidate surfactant protein A (SP-A), which has a major role in fighting infections and ... #1 FOR IMMEDIATE RELEASE "Proteomics of Human Lung Tissue Identifies surfactant Protein A as a Marker of Chronic Obstructive Pulmonary Disease" ...

Study links seabird deaths to soap-like foam produced by red-tide algae

... 23. "The problems we traditionally associate with harmful algal blooms are caused by toxins produced by the algae. In this case, it was a surfactant that removed the water-repellent properties of the feathers," said Raphael Kudela, professor of ocean sciences at the University of California, Santa ...

Study finds 'rescue course' of antenatal steroids improves outcome in premature babies

... in the "rescue steroid" group vs. placebo (43.9% vs. 63.6%) as well as significant decrease in respiratory distress syndrome, ventilator support, and surfactant use. When all neonates were included in the analysis (regardless of the gestational age at delivery), a significant reduction in composite morbidity ...

UT Southwestern researchers identify gene linked to inherited form of fatal lung disease

... are shared in common by all the individuals with the disease they were led to mutations in a gene called SFTPA2. The protein produced by this gene, surfactant protein A2, is found in the fluid of the lungs and helps protect the organ from invading pathogens. Many of the individuals in this family who ...

Environmental fate of nanoparticles depends on properties of water carrying them

... be able to remove nanoparticles from the water, Pennell explained. But you will have to be careful if the nanoparticles are stabilized by a natural surfactant or humic acid. If those are present in the water, the nanoparticles could go right through. In a continuation of the work, Pennell and his ...

Chemical compound present in detergents produce bacteria alterations in agricultural soils

... capacity with regards to microbiota as well as its biotransformation kinetics. The most utilized At this moment LAS is the most used anionic surfactant in the worldwide detergent market. Its international consumption reaches values of 2,000 kt per year and by the year 2010 it is expected to reach ...

American Chemical Society's Weekly Press Pac

... has spent years in fundamental studies of the backbone of any lotion a mixture or emulsion of oil and water. Along with a third ingredient, a surfactant that keeps the liquids from separating, emulsions are the basis of almost every skin lotion. Although the system may sound simplistic, Friberg said ...

American Chemical Society's Weekly PressPac -- Aug. 15, 2007

... a Pepfactant because it is made from peptides, the building blocks of proteins. One of the possible applications that we are aware of is a surfactant that would switch between the wash cycle and rinse cycle during clothes washing, which would mean you could remove visible suds without having to use ...

More>>

Surfactant in Biological Technology

'Nanosculpture' could enable new types of heat pumps and energy converters

... structures by carefully controlling the temperature, time, and amount of surfactant used during synthesis. "Our work is the first to demonstrate the ... synthesis at high temperatures or with low amounts of the biomolecular surfactant L-glutathonic acid (LGTA) yields branched nanorod structures in highly ...

Engineers whip up the first long-lived nanoscale bubbles

... colleagues, revealed that when the bubbles were covered with the chosen surfactant mixture, the surfactant molecules crystallized to form nearly impermeable shells over the bubble ...

Concentric Named Professional Agency of Record for Discovery Labs' SURFAXIN(R)

... Labs, will manage the account on the client side. Discovery Labs, headquartered in Warrington, Pa., is a biotechnology company developing novel surfactant replacement therapies (SRTs) with potential for application across the continuum of respiratory diseases, initially focusing on RDS in premature ...

Nasal Vaccine for Smallpox Confers High Levels of Immunity Without Safety Risks

... a series of preclinical vaccine studies that validate NanoBio's patented nanoemulsion platform, a suspension of oil, water, alcohol and antimicrobial surfactant together with antigens from specific pathogens. The nasally delivered vaccines easily penetrate mucous membranes, where dendritic cells engulf the ...

Anthrax vaccine produces immunity with nanoparticles, not needles

... to trigger a strong immune response by treating the inside of the animals noses with a nanoemulsion a suspension of water, soybean oil, alcohol and surfactant emulsified to create droplets of only 200 to 300 nanometers in size. It would take about 265 of the droplets lined up side by side to equal the width ...

Anthrax vaccine produces immunity with nanoparticles, not needles

... to trigger a strong immune response by treating the inside of the animals noses with a nanoemulsion a suspension of water, soybean oil, alcohol and surfactant emulsified to create droplets of only 200 to 300 nanometers in size. It would take about 265 of the droplets lined up side by side to equal the width ...

Sciclone ALH 3000 Liquid Handler: Functional Characterization of the High Volume Head - Part 1: Plate-to-Plate Precision Testing

Geoffrey Grove, Susan Ryan and Ed Alderman Applied Science and Technology Department, Caliper Life Sciences, Inc., Hopkinton, MA 01748 Overview The High Volume Head is one of four multi-channel liquid handling options available for the Sciclone ...

Technical Specifications Accelerating Your Research with the BD FACSCanto High Throughput Sampler Option

... The HTS integrates into the BD FACSCanto fluidics cart Recommended sheath solution BD FACS sheath solution with surfactant (Cat. No. 346524; Europe 336911) Performance Throughput ...
Surfactant in Biological Products

RC DC Protein Assay Kit I, bovine gamma-globulin standard from Bio-Rad

Description:... for 500 standard assays: 250 ml RC reagent I, 250 ml RC reagent II, 250 ml alkaline copper tartrate solution, 2 L dilute Folin reagent, 5 ml surfactant solution, and a bovine gamma-globulin ....
Company:Bio-Rad

RC DC Protein Assay Reagents Package from Bio-Rad

Description:... for 500 standard assays: 250 ml RC reagent I, 250 ml RC reagent II, 250 ml alkaline copper tartrate solution, 2 L dilute Folin reagent, and 5 ml surfactant ....
Company:Bio-Rad

Cleland’s Reagent from Calbiochem

Description:... GAS. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. A protective agent for SH groups. Does not contain waxy surfactant found in many other preparations. Blocks the lethal and hypnotic effects of pentobarbitol. Purity: ≥97% by titration. Contaminants: Heavy ...
Company:Calbiochem

Cleland’s Reagent from Calbiochem

Description:... GAS. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. A protective agent for SH groups. Does not contain waxy surfactant found in many other preparations. Blocks the lethal and hypnotic effects of pentobarbitol. Purity: ≥97% by titration. Contaminants: Heavy ...
Company:Calbiochem
Surfactant in Biological Dictionary

Alveoli

... Information on oxygen exchange, LaPlace's Law, inflation of alveoli , surfactant role in respiration, and exhalation. The alveoli are part of the ... Definition. Find Definitions For Any Word.Get Your Free Dictionary. ... surfactant counters the natural tendency of the alveoli to close (collapse) ... The ...
Other Contents
(Date:10/20/2014)... Columbus, OH (PRWEB) October 20, 2014 National ... Ohio Chapter of the American Academy of Pediatrics (Ohio AAP, ... Administration (NHTSA) in encouraging parents of teen drivers to talk ... hit the road. , Motor vehicle crashes are the leading ... 2,055 teen drivers involved in fatal crashes, and 859 (42%) ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Punzoné , ... in the U.S., has a lot to celebrate this month. ... country recognizes the achievements and contributions of Americans of Italian ... for Punzoné, and today it shares its favorite Italian cocktails ... trip to Italy - even if it is only in ...
(Date:10/19/2014)... October 20, 2014 The leading ... ( http://www.top10bestseohosting.com/go/iPage/ ) and GreenGeeks are the best ... platforms for those who want to buy high ... time. , The IT manager of Top10BestSEOHosting.com says, ... most recommended suppliers for everyone. A lot of ...
(Date:10/19/2014)... 2014 Having been working in the garment ... of customer needs. According to James, one of the company’s ... sequins, or with high-low skirts that add beauty to them. ... Recently, LunaDress has unveiled its new selection of 2014 long ... company’s brand new items are available in over 20 popular ...
(Date:10/19/2014)... 19, 2014 Visual Impact Frequency ... just been released to the public generating a ... building and fitness community. The commotion surrounding the ... Vin Delmonico prompting an investigative review. , "Many ... what is commonly known as a training 'plateau' ...
Breaking Medicine News(10 mins):Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 3Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 4Health News:Top10BestSEOHosting.com Considers iPage And GreenGeeks As The Best Dedicated Server Hosting Suppliers 2Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2Health News:Visual Impact Frequency Training Review: Rusty Moore's Latest Fitness Guide Released 2
(Date:10/15/2014)... ability to assess the pandemic risk from strains of ... must not allow ourselves to become complacent that the ... consortium of scientists. , Influenza pandemics arise when a ... to develop widespread immunity – spreads in the human ... past 100 years, the worst of which – the ...
(Date:10/15/2014)... 15, 2014 NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market releases photos and video of ... on Monday October 13 th . Gino ... and angel investor Mr. Chad A. Verdi rang ... NXT-ID thanked his investors and employees "for their work and dedication ...
(Date:10/14/2014)... Ohio (Oct. 14, 2014)—It,s been millions of years since ... a team led by Ohio University scientists is breathing ... model airflow through dinosaur snouts. The research has important ... only breathe but to enhance the sense of smell ... ,nosy, animals," said Ohio University doctoral student Jason Bourke, ...
Breaking Biology News(10 mins):Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3
Other TagsOther Tags