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Substitution in Medical News

Cephalon Announces FDA Advisory Committee Recommendation Against Approval of an Expanded Label for FENTORA

... patients) and/or improper dosing. The substitution of FENTORA for any other fentanyl product may ... fentanyl. As a result of these differences, the substitution of FENTORA for any other fentanyl product may ... fentanyl. As a result of these differences, the substitution of FENTORA for any other fentanyl product may ...

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

... Cardiotoxicity, infusion reaction, myelosuppression, liver impairment, substitution The use of DOXIL may lead to cardiac toxicity. Myocardial ... be reduced in patients with impaired hepatic function Accidental substitution has resulted in severe side effects. Do not substitute for doxorubicin HCl ...

In the Case of Epilepsy, Generic Drugs and Random Product Substitution are Not Always "Good Medicine"

... can be extremely dangerous. The primary problem with random product substitution is that the Food and Drug Administration (FDA) does not require generic ... switching from a brand name to a generic or being subject to the random substitution of one generic for another. The study is expected to begin shortly, and ...

Frost & Sullivan: Ageing Population and Availability of Preventative Medicines Propels Growth of European Eye Health Ingredients Market

... as varying regulations that are hampering eye health claims, threats of substitution and the lack of market credibility. Fluctuating prices and constant price ... ultimately depends on overcoming obstacles such as variant regulation, substitution threats and the impact of fluctuating economies and prices. Legislation, ...

Universal Health Realty Income Trust Reports 2008 Fourth Quarter and Full Year Financial Results

... with the previously disclosed Chalmette Medical Center asset exchange and substitution transaction, and; (iii) a gain of $264,000, or $.02 per diluted share, ... (12) - (264) Gain on asset exchange and substitution agreement with UHS - Chalmette - ...

Universal Health Realty Income Trust Reports 2008 First Quarter Financial Results

... disclosed Chalmette Medical Center ("Chalmette") asset exchange and substitution transaction. Favorably impacting net income during the quarter ended March ... property - (252) Gain on asset exchange and substitution agreement with UHS - Chalmette - (789) ...

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Substitution in Medical Technology

Spherix Announces Positive Phase 2 Study Results

... in nature. Prior Studies with Naturlose A recent controlled animal study demonstrated that, in comparison to sucrose, equivalent substitution of Naturlose as dietary carbohydrate results in less obesity, hyperglycemia, hyperlipidemia, and atherosclerosis (Police SB, Harris JC, Lodder RA, ...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

... * Severe myelosuppression may occur * DOXIL dosage should be reduced in patients with impaired hepatic function * Accidental substitution has resulted in severe side effects. Do not substitute for doxorubicin HCl on a mg per mg basis Contraindications * Patients with a ...

Comprehensive Safety Tests Published on Ruyan(R) Smoking Alternatives

... These products, varieties of replacement cartridges and their accessories are designed, manufactured and sold for the cigarette alternative/smoking substitution market. They allow smokers to satisfy their tobacco cravings in places and situations where they otherwise cannot smoke by law, regulation or common ...

Thrombosis Guidelines Emphasize Difficult Choices for Pregnant Women

... options for doing this: (1) continuing VKA but performing frequent pregnancy tests to determine when pregnancy has been achieved, followed by the substitution of LMWH or UFH as therapy; or (2) substituting VKAs with LMWH or UFH prior to conception. Although the second option eliminates the potential for ...

Two DOXIL(R) Studies to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... -- Severe myelosuppression may occur -- DOXIL dosage should be reduced in patients with impaired hepatic function -- Accidental substitution has resulted in severe side effects. Do not substitute for doxorubicin HCl on a mg per mg basis Contraindications -- Patients with a ...

BioMarin Initiates Phase 1 Clinical Study of PEG-PAL in PKU

... Phe concentrations in subjects with PKU. About PEG-PAL PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase) is an investigational enzyme substitution therapy for the treatment of PKU. Pharmacology studies conducted in the PKU mouse model demonstrated that weekly subcutaneous administrations of ...

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Substitution in Medical Products

Blind Performance Specimens

Description:... abnormal human urine test results for creatinine, specific gravity and pH. For use in assessing compliance with sample adulteration, dilution or substitution testing ....
Company:Bio-Rad Laboratories

PFC SIGMA Fixed Bearing Knee System Cruciate - Substituting

Description:... successful P.F.C. Total Knee System introduced in 1984, P.F.C. Sigma continues a history of innovation. Indicated for procedures where mechanical substitution is required for the posterior cruciate ligament, the cruciate substituting components may be used for primary or revision procedures. The femoral ...
Company:DePuy Orthopaedics, Inc.
Substitution in Medical Dictionary

Cardiopulmonary Resuscitation

... heart attack or near drowning , in which someone's breathing or heart beat has stopped. Cardiopulmonary resuscitation : The emergency substitution of heart and lung action to restore life to someone who appears dead. Cardiopulmonary Resuscitation (CPR) What is CPR? CPR stands for ...

Genetic Disorders

... Genetic disorders are caused by abnormalities ( mutation s) in your DNA. These abnormalities are formed by the erroneous addition, deletion or substitution of chemicals that make up your DNA. See all Pictures & Images Genetic disorders Almost all disease s have a genetic component, but the ...

Nicotine replacement

... Nicotine replacement products Smoking cessation drugs that contain nicotine are also called nicotine substitution products or nicotine replacement therapy. Nicotine replacement products for reducing withdrawal symptoms and craving. The antidepressants ...

Resuscitation

... heart attack or near drowning , in which someone's breathing or heart beat has stopped. Cardiopulmonary resuscitation : The emergency substitution of heart and lung action to restore life to someone who appears dead. Cardiopulmonary Resuscitation (CPR) What is CPR? CPR stands for ...

Smoking Cessation

... Cigarette Smoking and Cancer : Questions and Answers ... Smoking cessation drugs that contain nicotine are also called nicotine substitution products or nicotine replacement therapy. Smoking Cessation — If you are a smoker, stop smoking now. Studies have shown that babies ...

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Substitution in Biological News

Omega-3 fatty acids appear to impact AMD progression

... whole grain versions of pasta and bread, have a milder effect on blood sugar response. Earlier data published by Taylor and Chiu suggests that daily substitution of five slices of whole grain bread for white bread out of a total intake of 250 g of carbohydrate might cut out almost 8% of advanced AMD over five ...

Pliable proteins keep photosynthesis on the light path

... and protein, which differs in naturally occurring reaction center variants. The team may also conduct future experiments to understand the metal substitution limitations of the reaction center and track the protein movements that may be occurring in the reaction center that helps to optimize ....

Microbes fuel energy debate

... provide access to new bioenergy alternatives for the marketplace. In the context of a strong global political and economical debate on the gradual substitution of petroleum by renewable alternatives such as biofuels, Demain reviews how microbes can help solve the energy problem, and focuses on the organisms ...

High school students' paper published in prestigious college math journal

... the Law of Unintended Consequences. Student teams were required to address issues associated with increased corn-derived ethanol production and fuel substitution and relate these matters to dramatic and unanticipated rises in farm commodity pricing, the future of food supplies in developing nations, the effect ...

Synthetic virus supports a bat origin for SARS

... to "build" the consensus viral genome and several variations. The consensus synthetic SARS-like bat CoV did not initially grow in culture. But substitution of a single small region from human SARS-CoV the Spike protein receptor binding domain that is critical for viral entry into human cells allowed ...

Carbon sinks: Issues, markets, policy

... how this baseline rate could be doubled or more through activities including avoided deforestation, afforestation, improved forest management, and substitution of wood for other materials. Brian McPherson will discuss a project designing and deploying several pilot tests to validate the most promising CO ...
Substitution in Biological Technology

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... Cardiotoxicity, infusion reaction, myelosuppression, liver impairment, substitution The use of DOXIL may lead to cardiac toxicity. Myocardial ... be reduced in patients with impaired hepatic function Accidental substitution has resulted in severe side effects. Do not substitute for doxorubicin HCl ...

Shire begins the year with a strong performance

... 577.2 581.5 ________ ________ (1) Following substitution of the convertible bond to Shire plc in 2008, the Company no longer receives a tax deduction on its convertible bond interest, and the interest add ...

Spherix Announces 2008 Financial Results

... showed that mice fed sucrose became obese, hyperglycemic; and hyperlipidemic; and atherosclerosis was increased in these mice as well. Equivalent substitution of D-tagatose did not result in the same extent of these conditions and showed that D-tagatose did not promote substantial weight gain. The fat ...

Intra-Cellular Therapies Reports Positive Final Results of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

... impairment of attention, vigilance, information processing or declarative memory as measured by the Leeds Psychomotor Battery, Digit Symbol substitution Test or Word Pair Associates Test. Pharmacokinetic analyses revealed dose-related increases in exposure to ITI-007 and two metabolites with ...

BioTrends Releases TreatmentTrends(TM): US Nephrology, an Ongoing Syndicated Publication Providing Insight into Physician Perceptions and Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism

... dynamics will likely come from the recent introduction of generic calcium acetate from Roxane Laboratories, as very few Nephrologists oppose the substitution of a generic for Fresenius Medical Care's PhosLo. Another recent market shift came with the introduction of Genzyme's Renvela in Q108. Although the ...

EcoSphere(R) Biolatex(TM) Secures Funding from Granholm and Invest Michigan!

... platform provides EcoSphere biolatex products as replacements for petroleum-based paper and paperboard coating binders such as SB and SA Latex. At substitution levels up to 50 percent, the biolatex products are comparable or superior to traditional petroleum-based alternatives and can be specifically ...

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Substitution in Biological Products

m7G(5)ppp(5)G (Cap Analog) from Ambion

Description:... m7G(5')ppp(5')G (Cap Analog) is used for the synthesis of 5' capped RNA molecules in in vitro transcription reactions. substitution of cap analog for a large portion of the GTP in an in vitro transcription reaction results in the incorporation of the cap structure into a large ...
Company:Ambion

m7G(5)ppp(5)G (Cap Analog) from Ambion

Description:... m7G(5')ppp(5')G (Cap Analog) is used for the synthesis of 5' capped RNA molecules in in vitro transcription reactions. substitution of cap analog for a large portion of the GTP in an in vitro transcription reaction results in the incorporation of the cap structure into a large ...
Company:Ambion

RNA Cap Analog, Methylated from EPICENTRE Biotechnologies

Description:... A modified nucleotide structure called a ?cap? is present on the 5?-end of most naturally-occurring eukaryotic mRNAs and many viral RNAs. substitution of Cap Analog for a portion of the GTP present in an in vitro transcription reaction results in the synthesis of transcripts with a cap on the 5'-end ...
Company:EPICENTRE Biotechnologies

RNA Cap Analog, Unmethylated from EPICENTRE Biotechnologies

Description:... A modified nucleotide structure called a ?cap? is present on the 5?-end of most naturally-occurring eukaryotic mRNAs and many viral RNAs. substitution of Cap Analog for a portion of the GTP present in an in vitro transcription reaction results in the synthesis of transcripts with a cap on the 5'-end ...
Company:EPICENTRE Biotechnologies

RNA Cap Analog, Trimethylated from EPICENTRE Biotechnologies

Description:... A modified nucleotide structure called a ?cap? is present on the 5?-end of most naturally-occurring eukaryotic mRNAs and many viral RNAs. substitution of Cap Analog for a portion of the GTP present in an in vitro transcription reaction results in the synthesis of transcripts with a cap on the 5'-end ...
Company:EPICENTRE Biotechnologies
Substitution in Biological Definition

Alcohol

... 8.2.1 Deprotonation 8.2.2 Nucleophilic substitution 8.2.3 Dehydration 8.2.4 Esterification ... can (if activated first) undergo nucleophilic substitution reactions. For more details see the #Chemistry ... O (equilibrium to the left) Nucleophilic substitution The OH group is not a good leaving group ...

Neutral theory of molecular evolution

... or "unexpressed" (see synonymous or silent substitution ). Such changes are presumed to have little or no ... , multicellular organisms, the nucleotide substitution must arise within one of the many sex cells ... cases they may become "fixed"--meaning that the substitution they carry becomes a universal feature of the ...

Genetic code

... X = any nucleotide) tends to code for hydrophobic amino acids. However, the genetic code is not perfect as minor changes such as the single-base substitution in sickle cell anaemia is disasterous. The hydrophilic glutamate (Glu) is substituted by the hydrophobic valine (Val) which reduces the ...

Genetic code

... X = any nucleotide) tends to code for hydrophobic amino acids. However, the genetic code is not perfect as minor changes such as the single-base substitution in sickle cell anaemia is disasterous. The hydrophilic glutamate (Glu) is substituted by the hydrophobic valine (Val) which reduces the ...

Phospholipid

... amino alcohol formed from palmitate and serine . The amino terminal is acylated with a by a long-chain acyl CoA to yield ceramide . Subsequent substitution of the terminal hydroxyl group by phosphatidyl choline forms sphingomyelin. Sphingomyelin is present in all eukaryotic cell membranes , but ...

Species

... two population groups are so close that the distinction between them rests on an obscure and microscopic difference in morphology, or a single base substitution in a DNA sequence, then a demonstration of restricted gene flow between the populations will probably be difficult in any case. More typically, ...

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Substitution in Biological Dictionary

Substitution

... substitution cipher, in cryptography. substitution property, in Equality (mathematics)#Some basic logical ... Variable substitution , in first-order logic ... ...

Point Mutation

... these point mutations by the use of ... A point mutation or substitution is the most limited type of mutation , whereby a ... Sometimes the ... occurs when a single ... A point mutation results in a base pair substitution after replication and ... Point mutation summary with 3 pages of ...

Transversion

... In molecular biology, transversion refers to the substitution of a purine for a pyrimidine or vice versa . It can only be reverted by a spontaneous reversion. Because this type of mutation changes the ...

Ribonucleotides

... next in solution onto a ... use either deoxyribonucleotides (dNTPs) or ribonucleotides ... unable to use ribonucleotides , and the tyrosine substitution ... ribonucleotides ' binding ... Ribonucleotides are found in RNA (ribonucleic acid) and sometimes in DNA. ... The ribonucleotides must ...

Pyrimidine

... acid. C16H20BN3O3. Details. B10898 ... D evelopment of purine and pyrimidine analogues as potential anti ... This specific site of substitution on the pyrimidine ring was selected ... Online Shopping at DirectTextBook.com - Save up to 80%, buy or rent. New and used books like Purine and ...

Pribnow box

... TATA HOMOLOGY, HOMEOBOX, PROMOTER, BASE PAIR (bp) ... Roles of the Pribnow box in positive regulation of the ompC and ompF genes ... A base substitution at the Pribnow box renders ompF expression independent of a ... ...

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Other Contents
(Date:12/25/2014)... (PRWEB) December 25, 2014 The short film ... was created in honor of a true 9/11 hero, Welles ... film festivals including the 24 hours of Nuremberg International Short ... Bangladesh. , Actress, screenwriter and director Luciana Lagana ... this film together with her husband, Gregory Graham ...
(Date:12/25/2014)... Hills, California (PRWEB) December 25, 2014 ... her home in Woodland Hills, California after an 8 ... passed away on Christmas Eve evening in her home ... with aggressive metastatic breast cancer. , ... for over forty years, she pioneered and championed many ...
(Date:12/25/2014)... Dennis Thompson HealthDay Reporter ... sick children with complex chronic illnesses can receive effective, less ... home," with easy access to a team of dedicated health ... likely to become seriously ill and need either hospitalization or ... at an enhanced medical home clinic at the University of ...
(Date:12/25/2014)... WEDNESDAY, Dec. 24, 2014 (HealthDay News) -- Among early ... treatment, less than half of one percent will eventually ... new analysis reveals. The finding comes from a ... between 1998 and 2007, and it suggests that the ... double what experts had previously thought. "The frequency ...
(Date:12/25/2014)... New York, New York (PRWEB) December 25, 2014 ... ) continue to move forward in a number ... Southern District of West Virginia, Bernstein Liebhard LLP reports. ... the Court is scheduled to convene a Joint Status ... 2015, at 10:00 a.m. Parties have been directed to ...
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(Date:12/11/2014)... Minn. , Dec. 10, 2014  Data ... physiologic monitoring, has released a new series of ... of preclinical toxicology researchers. M series, part of ... toxicologists collect the best possible physiologic data when ... Adding functional endpoints to toxicology studies has ...
(Date:12/10/2014)... , Dec. 9, 2014  Wake Forest Baptist Medical Center ... for its School of Medicine. Funding for this $50 ... campaign that will be publicly launched next summer. ... in the former 60 series R.J. Reynolds Tobacco Company ... Construction will begin immediately with plans to be ready ...
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