Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...m of cholesterol) and triglycerides ?another fatty substance ?that are secreted into the bloodstream. PGC-1beta belongs to a specific family of co-activators, proteins that interact with other proteins to turn genes on and off and adjust their activity, like a dimmer switch that varies the brightness of a lig...Controversial drug shown to act on brain protein to cut alcohol use
...iathrough UCSF for medical research on alcohol and substance abuse, andby the Department of Defense....Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey
...s releases twosubstances into the environment. One substance sticks to foreign cells.The second substance reports back and tells the Enterococcus to makethe toxin. If no cells are in the area, the first sub...Sea skate experiment sheds light on human cell transport
...rchers made their discovery by using a plant-based substance to block an enzyme that causes phosphorylation. The result: The gates wouldn't open. These findings are published in the current issue of the American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, along with an accompanyi...... catheters, artificial joints and heart valves. A substance found on the surface of Staphylococcus epidermidis has, for the first time, been shown to protect the harmful pathogen from natural human defense mechanisms that would otherwise kill the bacteria, according to scientists at the Rocky Mountain Laborat...RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes
...se genesmay be indicative of the genotoxicity of a substance or its biologicallyactivated form. The primer sets may also be used to quickly amplify a region ofthe featured genes for later use as a probe in other analytical techniques, suchas Northern blot hybridization, nuclease protection assays or in situhyb...Sample Preparation for Microinjection
...njection is the loading or transfer of a dissolved substance into a living cell. The microscopic ti...This capillary is back loaded with the substance to be transferred into the cells cultured for microinjection. Typical substances include......microbiological bioburden, as it is a common substance in all kind of cells. Eppendorf Biopur products are ATP-free and therefore are optimally suited for use with ATP quantification kits. These kits commonly use the enzyme luciferase from firefly organs that catalyze the formation and ......n 5% CO 2 together with various dilutions of test substance (e.g., mitogens, cytostatic drugs, growth factors ...In some cases it may be preferable to add the test substance on Day 2 and incubate for a shorter length of time. <P > Day 2. 3. ......peptides. Members of this family include peptides, substance P (SP), neurokinin A (NKA), neurokinin B (NKB), and the recently discovered hemokinin-1 (1). Neurokinins are widely distributed throughout the central and peripheral nervous system where they act via G protein-coupled receptors (NK1, NK2, and NK3 rec...Nasal Spray Could Take Drugs Direct to Brain.
...to deliver insulin-like growth factor-1, a natural substance that has been shown to protect rat brains from str...is significant because researchers think this same substance may protect human brains from the devastating effects of stroke, but no one has been able to figure ...Heart disease threat starts early in life for Diabetics
...") cholesterol and increased blood homocysteine, a substance that is associated with heart disease risk.These results underscore the fact and the need to treat early on....Risk of heart disease begins in teens
..." cholesterol, and increased blood homocysteine, a substance that is associated with heart disease risk. Dr. Jody S Krantz, author of the study feels that early intervention is warranted and is mandatory in adolescents and young adults suffering from diabetes and possible association with atheroscerosis....... and it also has powerful anti-cancer properties.A substance called diallyl disulfide in garlic is known to make the gut produce enzymes that clear out cancer-causing particles. Now two New Zealand scientists have fed varying levels of disulfide to rats and found it increased levels of the cancer-protecting g......help increase fertility. The plant also contains a substance which controls lutenising hormone. This in turn increases progesterone production which keeps the menstrual cycle regular. The study followed 178 women diagnosed with PMS who suffered symptoms such as unstable mood, anger, anxiety, tiredness, sleep ...Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse
...abbreviated GC-MS. GC-MS can identify the specific substance ingested by recognizing not only the molecular structure of the original compound, but also its pattern of metabolites.......mn 2006. BF-200ALA, a gel that combines the active substance 5-aminolevulinic acid(ALA) with the nanoemulsion B...tes tumor tissuethrough a combination of an active substance and the irradiationwith red light. The placebo-controlled, randomized and double-blind study wascon...BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
...s significantrisk of a pandemic. An adjuvant is a substance that, when added to a vaccine,enhances the vaccine's effectiveness by stimulating an immunesystem response. In multiple studies, BioVant has been shown to besafe and cause minimal dose-dependent inflammation at the injectionsite, and has been shown t......nor the patient knows if placebo or the activedrug substance is applied. EASI: Eczema Area and Severity Index (EASI), a commonly appliedtest to assess the extent and severity of AD. Hypersensitivity: an excessive immune reaction. Immunotherapeutic:a product aimed at activation of the immune system to modify an......nor the patient knows if placebo or the activedrug substance is applied. Enzyme: protein that acts as a catalyst and enables or enhanceschemical reactions within cells. Half-life: time required in which half the amount of a biologicalsubstance (e.g. antibodies) is removed from the organism. Hypertension: high ...