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Somatic in Medical News

Is somatic hypersensitivity a predictor of irritable bowel syndrome?

... of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. ... have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others ... conflicting findings may result from differing somatic pain testing procedures. Previous studies have ...

New oncogene gives valuable insight into hepatocellular tumors in humans

... 23 April: The first identification of GP130 somatic activating mutations* in human tumours was ... Denmark. Identification of recurrent somatic mutation activating GP130 in inflammatory ... with obesity and alcohol intake. Recently, somatic mutations were identified that activated GP130 in ...

New advancements in the use of adult, embryonic stem cells for tissue regeneration

... The recently acquired ability to reprogram adult somatic cells to ESCs in culture ("induced pluripotent ... concerns surrounding the destruction of somatic cell nuclear transfer embryos to make personal ... differentiation and survival time of reprogrammed somatic cells, and the need to develop methods to ...

Culture and depression

... 1. East-Asian participants will emphasize somatic or physical symptoms of depression more than ... social context, resulting in a cascade of somatic and psychological experiences that are ... did report a significantly higher level of somatic symptoms when reporting through the spontaneous ...

21st Congress of the College of Neuropsychopharmacology, Aug. 30-Sept. 3, 2008, Spain

... and academic career, social functioning and somatic health throughout life, frequently associated ... 290 billion euros (Wittchen et al., 2005). Unlike somatic diseases with their typically high direct costs, ... recognized and treated, the treatment of comorbid somatic illnesses is usually less efficient and therefore ...

St. Jude finds 'dancing' hair cells are key to humans' acute hearing

... theoriescalled stereociliary motility and somatic motilitythat have resulted from previous studies ... of cilia extending from the outer hair cells. The somatic motility theory proposes that the sound signal is ... Since the prestin protein is the key component of somatic motility, in previous experiments Zuo and his ...

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Somatic in Medical Technology

St. Jude Finds 'Dancing' Hair Cells Are Key to Humans' Acute Hearing

... of cilia extending from the outer hair cells. The somatic motility theory proposes that the sound signal ... Since the prestin protein is the key component of somatic motility, in previous experiments Zuo and his ... a hearing defect that indicated a malfunction of somatic motility. While the knockout experiments were ...

Study Reports Successful Cloning of Human Embryo Using Adult DNA

... ) The experiments, using a technique called somatic cell nuclear transfer (SCNT), provide key steps ... cloned embryos up to blastocyst stage using adult somatic [skin] cells as donor cells. This is a key ... of Human Cloned Blastocysts Following somatic Cell Nuclear Transfer (SCNT) with Adult ...

ARUP Laboratories Applauds FDA's Decision on the Value of KRAS-Mutation Testing in Colorectal Cancer

... test colorectal cancer to determine whether a particular therapeutic strategy should be used by oncologists. Most colorectal cancer is caused by somatic mutations and is not hereditary. Mutations in the oncogene KRAS are seen in over 40 percent of sporadic colorectal cancers. While several ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... . Accessed May 2009. Carvajal RD, et al. A phase II study of Imatinib mesylate (IM) for patients with advanced melanoma harboring somatic alterations of KIT. Abstract # 9001. American Society of Clinical Oncology 2009 Annual Meeting, Orlando, FL. Hainsworth J et al. Phase II ...

Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs

... normal human embryos. The paper is available free online at www.liebertpub.com/clo . Since the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate personalized stem cells to repair the body without fear of tissue ...

Research Teams at J. Craig Venter Institute and Ludwig Institute for Cancer Research Uncover New Chromosomal Alterations in Cancer Using Transcriptome Sequencing Approach

... coverage this approach could be a powerful and efficient way to discover all events associated with expressed genes including gene fusions, somatic mutations and alternative trans-splicing that lead to the development of cancer. Robert Strausberg, Ph.D., Deputy Director of the JCVI and ...
Somatic in Medical Products

Total T4 RIA Test

Description:... [1,2]. Less than 0.1% of the total T4 circulates in a free or unbound form. T4 binds to specific cell receptors and has diverse cellular and somatic effects. Measurement of total serum T4 levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid ....
Company:Diagnostic Systems Laboratories, Inc.

Total T4 EIA Test

Description:... [1,2]. Less than 0.1% of the total T4 circulates in a free or unbound form. T4 binds to specific cell receptors and has diverse cellular and somatic effects. Measurement of total serum T4 levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid ....
Company:Diagnostic Systems Laboratories, Inc.
Somatic in Medical Definition

Somatic dysfunction

... In osteopathic medicine , somatic dysfunction is the impaired or altered function ... 4 Sources Diagnosis somatic dysfunction is diagnosed by physical examination. ... Significance The physical manifestation of somatic dysfunction is frequently associated reciprocally ...

Medicine

... with systemic diseases of adults, i.e. those diseases that affect the body as a whole (restrictive, current meaning), or with all adult non-operative somatic medicine (traditional, inclusive meaning), thus excluding pediatrics, surgery, gynaecology and obstetrics, and psychiatry. There are several ...
Somatic in Medical Dictionary

Mutation

... when occurring in heterozygous condition with a contrasting allele. somatic mutation An alteration in DNA that occurs after conception . somatic mutation s can occur in any of the cells of the body except the germ ...

Respiration

... the rate of respiration . TAT: One of the regulatory genes of HIV . somatic death is characterized by the discontinuance of cardiac activity and ... cells from lack of oxygen , although for approximately six minutes after somatic death — ... Paced Respiration (Relaxation Therapy) Pain ( ...

Conception

... an X or a Y chromosome . These X and Y chromosomes determine the child's genetic sex. An alteration in DNA that occurs after conception . somatic mutation s can occur in any of the cells of the body except the germ cells ( sperm and egg) and therefore are not passed on to children. The ...

Macroglossia

... mouth cavity . Search All of MedicineNet For: search help ... Overgrowth syndrome s are the result of excessive prenatal and postnatal somatic growth, and result in macroglossia , nephromegaly, and hemihypertrophy . Macroglobulinemia - Primary (Macroglobulinemia of Waldenstrom) ...

Vision

... the A.C.N.M. Foundation Board of Trustees will present the Dorothea M. Lang Pioneer during the ACNM Annual Meeting. The process of di vision of somatic cells in which each daughter cell receives the same amount of DNA as the parent cell . mitotane An anti cancer drug used in treating ...
Somatic in Biological News

Protecting cells from their neighbors

... body organs and tissues -, and that comprise the somatic cell line. Scientists at the Institute for ... CSIC, have identified the mechanism that protects somatic cells against the behaviour of germ cells. When ... but whose signalling also reaches neighbouring somatic cells. The researchers have now discovered that ...

Recruitment of reproductive features into other cell types may underlie extended lifespan in animals

... These germline cells generate their offspring's somatic cells other cells involved in all aspects of ... of the C. elegans roundworm induce 'mortal' somatic cells to express some of the genes that allow the ... programs normally restricted to the germline into somatic cells," says Sean Curran, PhD, of MGH Molecular ...

Therapeutic cloning gets a boost with new research findings

... rate of spontaneous point mutations than adult somatic cells, which give rise to the body's remaining ... higher mutation rates, however, adult somatic cells are used as the donor cells in a cloning process called somatic cell nuclear transfer (SCNT). This made ...

Researchers generate functional neurons from somatic cells

... stem (iPS) cells, which are engineered from adult somatic cells and can differentiate into most other cell ... support the possibility that reprogrammed somatic cells might prove to be a viable alternative to ... "It seems possible that disease-specific somatic cells may be reprogrammed and utilized to model, ...

Animal eggs not suitable substitutes to produce stem cells

... the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered ... in a paper entitled, "Reprogramming of Human somatic Cells Using Human and Animal Oocytes." The ... then be differentiated to become any type of somatic cell and used for cell or tissue repair or ...

New route for heredity bypasses DNA

... the cell, these ciliate cells have two. One, the somatic nucleus, contains the DNA needed to carry out all ... When two of these ciliate cells mate, the somatic nucleus gets destroyed, and must somehow be ... of it is thrown away during regeneration of a new somatic nucleus, in a process that compresses a pretty ...

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Somatic in Biological Technology

Animal Eggs Not Suitable Substitutes to Produce Stem Cells

... the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered ... in a paper entitled, "Reprogramming of Human somatic Cells Using Human and Animal Oocytes." The ... then be differentiated to become any type of somatic cell and used for cell or tissue repair or ...

Transgenomic Completes Licensing Option With Dana-Farber Cancer Institute on Cold-PCR for Enrichment of DNA Mutations

... in samples where DNA sequencing cannot detect very low concentrations of somatic DNA mutation. "We are very excited to be able to work with ... Nuclease promises a significant solution to high sensitivity detection of somatic mutations that are key to cancer biology." Cold-PCR will have ...

Advanced Instruments Acquires D & F Control Systems Inc.

... F Control Systems manufactures and markets milk preservative products and somatic cell dyes for laboratories around the world. Their patented preservatives ... for cryoscopy, pasteurization confirmation, component analysis and somatic cell counting. The company provides products that are internationally ...

Roche Signs Exclusive Distribution Deal with DxS for K-RAS and EGFR Cancer Mutation Tests

... EGFR 29 Test is designed to enable detection of 29 of the most common somatic mutations in the EGFR gene and detects mutations with greater sensitivity ... studies in non-small cell lung cancer have shown that some patients carry somatic mutations in the epidermal growth factor receptor (EGFR) gene. These ...

Stemagen First to Create Cloned Human Embryos From Adult Cells

... world to create, and meticulously document, a cloned human embryo using somatic cell nuclear transfer (SCNT). Stemagen CEO Samuel H. Wood, M.D., Ph.D., ... author on the paper, "Development of Human Cloned Blastocysts Following somatic Cell Nuclear Transfer (SCNT) with Adult Fibroblasts." "No other ...

New Phase III Data Demonstrate Oxycodone / Naloxone Combination Tablet Reduces Opioid-Induced Bowel Dysfunction in Patients With Chronic Severe Pain

... has been demonstrated across a broad spectrum of pain states such as somatic and neuropathic pain(5,6). Recent experimental data in healthy volunteers ... moderate to severe cancer and severe non-cancer related pain types such as somatic (e.g. osteoarthritis), neuropathic (e.g. diabetic neuropathy) and visceral ...

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Somatic in Biological Products

Mouse Anti-Salmonella typhimurium Monoclonal Antibody, Unconjugated, Clone 6331 from GeneTex

Description:... bacilli that are facultative and flagellated (motile). Salmonellae possess 3 major antigens; the "H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). Salmonellae also possess the LPS ...
Company:GeneTex
Somatic in Biological Definition

Gene therapy

... In theory it is possible to transform either somatic cells (most cells of the body) or cells of the ... therapy so far in people has been directed at somatic cells, whereas germline engineering in humans ... the chromosomes by genetic recombination . somatic gene therapy can be broadly split in to two ...

Allele frequency

... locus, c) a population of individuals carrying n loci in each of their somatic cells (e.g. two loci in the cells of diploid species, which contain two ... allele (i.e. carry one copy of that allele and one copy of another in each somatic cell) and 4% will be homozygous (carrying two copies of the allele). So ...

Gamete

... from two to one (i.e., produces haploid gametes). The diploid somatic cells of an individual will contain one copy of the chromosome set from ... not exact duplicates of either of the sets of chromosomes carried in the somatic cells of the individual that produced the gametes. They can be "hybrids" ...

Nervous system

... sensory pathways and motor pathways , the latter being divided into the somatic (voluntary) nervous system and the autonomic nervous system . The somatic nervous system is the voluntary part of the nervous system that ...

Allele

... red petals, while another might result in white petals. Some organisms are diploid - that is, they have paired homologous chromosomes in their somatic cells , and thus contain two copies of each gene. An organism in which both copies of the gene are identical - that is, have the same allele - is ...

Antibody

... they are specific for and that elicited their production. The ability to bind a wide variety of foreign antigens arises from events know as somatic recombination. This is when genes are selected (variable (V), diversity (D) and joining (J) for heavy chains, and only V and J for light chains) to ...

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Somatic in Biological Dictionary

Somatic hypermutation

... somatic hypermutation (or SHM) is a mechanism inside ... used by the immune system to ... somatic hypermutation somatic hypermutation (or SHM ) is a mechanism inside ...

Somatic cells

... somatic cells are any cells forming the body of an ... and ova, the cells from ... The term somatic refers to cells of the body, rather than gametes (eggs or sperm). In humans, somatic cells contain two copies of each chromosome ...

Somatic cell

... somatic cells are any cells forming the body of an ...ch... In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory ... stem cell research, ... ... where somatic refers to cells of the body (not the germ ...

Somatic

... The term somatic refers to cells of the body, rather than gametes (eggs or sperm). In humans, somatic cells contain two copies of each chromosome ... of each chromosome (haploid). Although all somatic cells of an individual are genetically identical ...

Reflex arc

... arc ... Reflex arc - Wikipedia, the free encyclopedia ... Example: somatic Reflex Arc . A somatic reflex arc is one in which there is the simplest possible arrangement ...

Polycistronic

... precursors into mature monocistronic ... ... of murine and human somatic cells using a single polycistronic vector. ... hips, ips, klf4, oct4, ... self-cleaving-peptide, sox, ... Reprogramming of murine and human somatic cells using a single polycistronic vector. ... ips, klf4, oct4, ...

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