Mitochondrial DNA mutations play significant role in prostate cancer
...he researchers found both germ-line(inherited) and somatic (acquired) mutations in the prostate cancersamples.Because COI mutations are known to be more common in individuals ofAfrican descent, the scientists also analyzed a group of patients andcontrols of European ancestry. In this group they found the COI...Of mice and men's (and women's) contraceptives
... opposed to all other cell types, which are called somatic cells. "There are many proteins whose deletion wil... male and female infertility without affecting the somatic cells." Animals deficient in the protein ?called MSY2 ?are infertile, but are otherwise healthy and...Scientists generate patient-specific stem cells, Science study says
...imilar cell line from a woman who donated both the somatic cell and the oocyte; however, the donor was a spinal cord patient. The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. Other improvements over the last pap...SuperLigands - a database of ligand structures derived from the Protein Data Bank
...imilar cell line from a woman who donated both the somatic cell and the oocyte; however, the donor was a spinal cord patient. The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. Other improvements over the last pap......tablished that fetal mammalian eggs originate from somatic stem cells. More recent research of adult human ovaries has shown that oocytes and granulosa cells (the layer of small cells that form the wall of the ovarian follicle) may originate from OSE cells and assemble together to form new primary follicles ...Mouse Anti-Salmonella typhimurium Monoclonal Antibody, Unconjugated, Clone 6331 from GeneTex
..."H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). Salmonellae also possess the LPS endotoxin characteristic of Gram-negative bacteria. This LPS is composed of an "O" polysaccharide ("...Principles and applications of electrical cell fusion
...his enucleated oocyte is then fused with a somatic cell (e.g. from connective tissue). This is carried out by using electrical cell fusion because it is the only method efficient enough to produce the desired result. The fusion product is implanted into a surrogate mother and i...Principles and applications of electrical cell fusion
...his enucleated oocyte is then fused with a somatic cell (e.g. from connective tissue). This is carried out by using electrical cell fusion because it is the only method efficient enough to produce the desired result. The fusion product is implanted into a surrogate mother and i......arrays for the identification of fetal and somatic liver stem cells. The microarrays will be used for the examination of the differentiation status of these cells, which is influenced by certain factors of the extra-cellular microenvironment in vitro. The results are o...RNA Interference and Gene Silencing: History and Overview
..."enhancer of glp-1 "), RNAi functions normally in somatic cells, but is defective in germline cells where ego-1 is primarily expressed. In Arabidopsis SDE-1 / SGS-2 mutants ("SGS" stands for suppressor of gene silencing), siRNAs are produced when dsRNA is introduced via an endoge...The Genesis of Gendicine: The Story Behind the First Gene Therapy
.... Guidance for industry: Guidance for human somatic cell therapy and gene therapy. 1998 Mar 30....Health of China.Points to consider on human somatic cell therapy and gene therapy. Beijing: 1993 May 1. SDA China.Administration for drug ...A need for new stem cell lines
...stepping the problem is through a process known as somatic cell nuclear transfer or SCNT. That procedure, also known as therapeutic cloning, involves taking DNA from a cell belonging to a patient and inserting it into an egg whose nucleus has been removed. When the cell divides, it produces stem cells that c...How to repeal male infertility?
...ontact between various cells including ones called somatic Sertoli cells. When Sertoli cells are dysfunctional, sperm production is interrupted. Currently, there is no way to repair dysfunctional Sertoli cells. Researchers from the Hopkins University, led by Inder Verma, used gene therapy to correct Sertoli...New Stem Cells lines will be required
...stepping the problem is through a process known as somatic cell nuclear transfer or SCNT. That procedure, also known as therapeutic cloning, involves taking DNA from a cell belonging to a patient and inserting it into an egg whose nucleus has been removed. When the cell divides, it produces stem cells that c...Perfect babies boon or a bane?
...rk Frankel said “IGM utilising current methods for somatic gene transfer cannot presently be carried out responsibly on humans." The report recommends that human trials of inheritable genetic changes should not be initiated until reliable techniques for gene correction or replacement are developed that meet ......he University of Edinburgh, UK. Hwang’s team used somatic cell nuclear transfer, the same technique used to create Dolly. To clone Snuppy, the researchers implanted nuclei from his father’s ear cells into eggs from female dogs, having removed the eggs’ nuclei. By passing a small electric shock to start deve...Millipore Corporation Announces New ReNcell Data from Collaboration with ReNeuron
... leading player in the stem cell field,using human somatic stem cells to develop leading edge therapiesfor neurodegenerative and other diseases. The Group has alsoleveraged their stem cell technologies into non-therapeutic areassuch as drug discovery. ReNeuron was founded in 1997 tocommercialize technology...Data Suggest Cymbalta Improved Functioning in Patients with Generalized Anxiety Disorder
...cal symptoms and 7 percent was fromimprovements in somatic anxiety associated with GAD. Since GAD presents w...cal symptoms and 4 percent was due to treatment of somatic anxiety, while 51 percent was due to an undefined effect of Cymbalta. -- In improvement i...