somatic

Mitochondrial DNA mutations play significant role in prostate cancer

...he researchers found both germ-line(inherited) and somatic (acquired) mutations in the prostate cancersamples.Because COI mutations are known to be more common in individuals ofAfrican descent, the scientists also analyzed a group of patients andcontrols of European ancestry. In this group they found the COI...

Of mice and men's (and women's) contraceptives

... opposed to all other cell types, which are called somatic cells. "There are many proteins whose deletion wil... male and female infertility without affecting the somatic cells." Animals deficient in the protein ?called MSY2 ?are infertile, but are otherwise healthy and...

Scientists generate patient-specific stem cells, Science study says

...imilar cell line from a woman who donated both the somatic cell and the oocyte; however, the donor was a spinal cord patient. The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. Other improvements over the last pap...

SuperLigands - a database of ligand structures derived from the Protein Data Bank

...imilar cell line from a woman who donated both the somatic cell and the oocyte; however, the donor was a spinal cord patient. The ten additional new lines resulted from nuclear transfer with skin cells of males or females and oocytes from biologically-unrelated females. Other improvements over the last pap...

Human Eggs Can Develop From Ovarian Surface Cells In Vitro

...tablished that fetal mammalian eggs originate from somatic stem cells. More recent research of adult human ovaries has shown that oocytes and granulosa cells (the layer of small cells that form the wall of the ovarian follicle) may originate from OSE cells and assemble together to form new primary follicles ...

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somatic at Biology Products

Mouse Anti-Salmonella typhimurium Monoclonal Antibody, Unconjugated, Clone 6331 from GeneTex

..."H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). Salmonellae also possess the LPS endotoxin characteristic of Gram-negative bacteria. This LPS is composed of an "O" polysaccharide ("...

somatic at Biology Technology

Principles and applications of electrical cell fusion

...his enucleated oocyte is then fused with a somatic cell (e.g. from connective tissue). This is carried out by using electrical cell fusion because it is the only method efficient enough to produce the desired result. The fusion product is implanted into a surrogate mother and i...

Principles and applications of electrical cell fusion

...his enucleated oocyte is then fused with a somatic cell (e.g. from connective tissue). This is carried out by using electrical cell fusion because it is the only method efficient enough to produce the desired result. The fusion product is implanted into a surrogate mother and i...

An Optimal DNA Microarray Substrate for the Identification of Fetal and Somatic Liver Stem Cells of the Rat

...arrays for the identification of fetal and somatic liver stem cells. The microarrays will be used for the examination of the differentiation status of these cells, which is influenced by certain factors of the extra-cellular microenvironment in vitro. The results are o...

RNA Interference and Gene Silencing: History and Overview

..."enhancer of glp-1 "), RNAi functions normally in somatic cells, but is defective in germline cells where ego-1 is primarily expressed. In Arabidopsis SDE-1 / SGS-2 mutants ("SGS" stands for suppressor of gene silencing), siRNAs are produced when dsRNA is introduced via an endoge...

The Genesis of Gendicine: The Story Behind the First Gene Therapy

.... Guidance for industry: Guidance for human somatic cell therapy and gene therapy. 1998 Mar 30....Health of China.Points to consider on human somatic cell therapy and gene therapy. Beijing: 1993 May 1. SDA China.Administration for drug ...

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somatic at Biology Definition

X chromosome

...mosomes is randomly and permanently inactivated in somatic cells (cells other than egg and sperm cells). This phenomenon is called X-inactivation or Lyonization. X-inactivation ensures that females, like males, have one functional copy of the X chromosome in each body cell. Identifying genes on each chr...

Stem cell

... and conditions. They are more accurately called somatic (Greek σωμα sōma = body) stem cells, because they need not come from adults but can also come from children or umbilical cords. Embryonic stem cells are cultured cells obtained from the inner mass cells of a blastocys...

Selective serotonin reuptake inhibitor

... discontinuing their use is known to produce both somatic and psychological withdrawal symptoms, a phenomenon known as "SSRI discontinuation syndrome" (Tamam & Ozpoyraz, 2002). Compared to the withdrawal symptoms of such drugs as opiates , alcohol or cocaine , these are slight. Their effectiven...

Paternity testing

...idual is almost exactly the same in each and every somatic cell . Sexual reproduction brings the DNA of both parents together randomly to create a unique combination of genetic material in a new cell, so the genetic material of an individual is derived from the genetic material of their parents. This gene...

Nervous system

...otor pathways , the latter being divided into the somatic (voluntary) nervous system and the autonomic nervous system . The somatic nervous system is the voluntary part of the nervous system that coordinates a body's movements, such...

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somatic at Biology Dictionary

Viscera

...tion as pain signals trans mitted by the sensory- somatic system are. Full article >>> viscera l mass The region of a mollusc's body that contains viscera l organ s. Viscera l organ s of the thoracic, abdominal, and pelvic cavities. viscosity the resistance of water molecule s to exter...

Virus

...ensed single X- chromosome seen in the nuclei of somatic cells of female mammals . Full article >>> capsid The protein coat of a virus particle. carbanion A negatively charged carbon atom . carbocation (AKA) carbonium ion A positively charged carbon atom . Full article >>&...

Theory

...of immunoglobulin but trans cribes only one. See somatic mutation theory . Full article >>> The neutral theory of molecular evolution (also, simply the neutral theory of evolution ) is an influential theory that was introduced with provocative effect by Motoo Kimura in the late ...

Telomerase

...duction of gametes . It is not normally found in somatic cells . Cyclin-Dependent Kinase s Some cells stop dividing in G1; others stop in G2. Full article >>> Telomerase and telomere s have been full of surprises for us and there's a great deal we don't understand about exactly how it ...

Syncytium

...aginate, dividing the syncytium into individual somatic cells . Full article >>> It is also unique among model organ isms in that cleavage occurs in a syncytium . Full article >>>...

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somatic at Medicine News

A need for new stem cell lines

...stepping the problem is through a process known as somatic cell nuclear transfer or SCNT. That procedure, also known as therapeutic cloning, involves taking DNA from a cell belonging to a patient and inserting it into an egg whose nucleus has been removed. When the cell divides, it produces stem cells that c...

How to repeal male infertility?

...ontact between various cells including ones called somatic Sertoli cells. When Sertoli cells are dysfunctional, sperm production is interrupted. Currently, there is no way to repair dysfunctional Sertoli cells. Researchers from the Hopkins University, led by Inder Verma, used gene therapy to correct Sertoli...

New Stem Cells lines will be required

...stepping the problem is through a process known as somatic cell nuclear transfer or SCNT. That procedure, also known as therapeutic cloning, involves taking DNA from a cell belonging to a patient and inserting it into an egg whose nucleus has been removed. When the cell divides, it produces stem cells that c...

Perfect babies boon or a bane?

...rk Frankel said “IGM utilising current methods for somatic gene transfer cannot presently be carried out responsibly on humans." The report recommends that human trials of inheritable genetic changes should not be initiated until reliable techniques for gene correction or replacement are developed that meet ...

SNUPPY – Woo Suk Hwang reveals World’s first dog cloe

...he University of Edinburgh, UK. Hwang’s team used somatic cell nuclear transfer, the same technique used to create Dolly. To clone Snuppy, the researchers implanted nuclei from his father’s ear cells into eggs from female dogs, having removed the eggs’ nuclei. By passing a small electric shock to start deve...

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somatic at Medicine Products

Total T4 EIA Test

...ecific cell receptors and has diverse cellular and somatic effects. Measurement of total serum T4 levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid hormones. IN: Division of Drugs and Toxicology, American Medical Association: Drug Evaluations Annual 1995. Ame...

Total T4 RIA Test

...ecific cell receptors and has diverse cellular and somatic effects. Measurement of total serum T4 levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid hormones. IN: Division of Drugs and Toxicology, American Medical Association: Drug Evaluations Annual 1995. Ame...

somatic at Medicine Technology

Millipore Corporation Announces New ReNcell Data from Collaboration with ReNeuron

... leading player in the stem cell field,using human somatic stem cells to develop leading edge therapiesfor neurodegenerative and other diseases. The Group has alsoleveraged their stem cell technologies into non-therapeutic areassuch as drug discovery. ReNeuron was founded in 1997 tocommercialize technology...

Data Suggest Cymbalta Improved Functioning in Patients with Generalized Anxiety Disorder

...cal symptoms and 7 percent was fromimprovements in somatic anxiety associated with GAD. Since GAD presents w...cal symptoms and 4 percent was due to treatment of somatic anxiety, while 51 percent was due to an undefined effect of Cymbalta. -- In improvement i...

somatic at Medicine Definition

Somatic dysfunction

In osteopathic medicine , somatic dysfunction is the impaired or altered function o... Significance The physical manifestation of somatic dysfunction is frequently associated reciprocally with visceral illness. Similarly, the resolution o...

Medicine

... current meaning), or with all adult non-operative somatic medicine (traditional, inclusive meaning), thus excluding pediatrics, surgery, gynaecology and obstetrics, and psychiatry. There are several subdisciplines of internal medicine: Cardiology Endocrinology Gastroenterology Hematology ...

somatic at Medicine Dictionary

Vision

...cle >>> The process of di vision of somatic cells in which each daughter cell receives the same amount of DNA as the parent cell . mitotane An anti cancer drug used in treating adrenocortical cancer and ACTH -producing pituitary tumor s (Cushing's disease ). Full article >>...

Respiration

...gen , although for approximately six minutes after somatic death — ... Full article >>> Paced Respiration (Relaxation Therapy) Pain ( Chronic Pain ) Pain Management ( Chronic Pain ) Posttraumatic Stress Syndrome ( Post-Traumatic Stress Disorder ) Post-Traumatic Stress Disorde...

Mutation

...ontrasting allele. Full article >>> somatic mutation An alteration in DNA that occurs after conception . Somatic mutation s can occur in any of the cells of the body except the germ cells ( sperm and egg) and therefore are not passed on to children. Full article >>> Adapt...

Macroglossia

...e the result of excessive prenatal and postnatal somatic growth, and result in macroglossia , nephromegaly, and hemihypertrophy . Full article >>> Macroglobulinemia - Primary (Macroglobulinemia of Waldenstrom) Macroglobulinemia of Waldenstrom Macroglossia Macrophage ( Histiocyte ) M...