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Smallpox in Medical News

Smallpox -- the death of a disease

... staff. On October 26, 1976, the last case of smallpox occurred. The disease that annually had killed ... in just over ten years. "The eradication of smallpox was the greatest public health accomplishment of ... Fenn, author of Pox Americana: The Great smallpox Epidemic of 1775-82, and Associate Professor of ...

Scientists discover how smallpox may derail human immune system

... Florida researchers have learned more about how smallpox conducts its deadly business discoveries that ... looked at all of the proteins produced by the smallpox virus in concert with human proteins, and ... for the first time systematically screened the smallpox proteome the entire complement of new proteins ...

Dr. Larry Brilliant Joins Jeff Skoll to Combat Global Challenges

... with the World Health Organization in eradicating smallpox from Asia. He was the founding executive director ... that led the successful World Health Organization smallpox eradication program in India and South Asia. He ... authored two books, including The Management of smallpox Eradication in India , and dozens of scientific ...

Japanese Researchers Develop New Smallpox Vaccine

... News) -- A third-generation tissue-cultured smallpox vaccine shows promise, Japanese researchers report. "The threat of smallpox bioterrorism has prompted reconsideration of the need for smallpox vaccination," the researchers noted. "Serious ...

Oklahoma State University researchers make breakthrough against poxviruses

... Stillwater, Okla. smallpox has a nasty history throughout the world. Caused by poxviruses, smallpox is one of the few disease-causing agents against ... step towards a pharmaceutical medication for smallpox and the emerging human monkeypox. The human ...

Effective health messages may yield vaccine compliance among ER workers

... vaccinate 500,000 healthcare workers against the smallpox virus, which theoretically could be used in a ... the importance of various aspects of the smallpox vaccination in four separate scenarios: Today, with no smallpox outbreak4; if another terrorist attack happened ...

NIH awards LIAI major grant to test safety of new smallpox treatment

... of an antibody treatment that quickly fights the smallpox virus. The treatment could be the nations first ... in protecting against a terrorist-originated smallpox outbreak and may eventually be stockpiled nationwide alongside the smallpox vaccine. This work is particularly important ...

Nanoemulsion vaccines show increasing promise

... able to produce a strong immune response against smallpox and HIV in two new studies. The results build ... diverse materials. We used whole virus in the smallpox vaccine. In the HIV vaccine, we used a single ... and hepatitis B. Potential for a better smallpox vaccine ...

Researchers uncover more about how poxviruses evade the immune system

... about a key protein that allows viruses such as smallpox to replicate and wreak havoc on the immune ... rheumatoid arthritis. Of all the poxviruses, smallpox in particular has played a gruesome role in human ... million deaths in the 20th century alone. Though smallpox was declared officially eradicated in 1979, many ...

Smallpox vaccine alternative identified

... of a potential alternative to the existing smallpox vaccine that can replace the current biodefense ... in human and animal studies as the current smallpox vaccine, Dryvax. The study is part of a national ... an effective and safer vaccine to the public. smallpox was declared eradicated worldwide in 1980; the ...

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Smallpox in Medical Technology

The Government of Canada Procures IMVAMUNE(R) Smallpox Vaccine for the Country's Biological Preparedness

... intent to procure an MVA-based, third generation smallpox vaccine, Public Works and Government ... announced financial guidance for 2008. smallpox and the need for a new vaccine smallpox is the most dangerous infectious disease ever ...

Bavarian Nordic Reports Successful Safety Data From Phase II Study With IMVAMUNE(R)

... emergency. In support of using IMVAMUNE(R) as a smallpox vaccine in individuals otherwise contraindicated ... are excluded from vaccination with traditional smallpox vaccines. The complete data set from this trial ... a history of previous exposure to a conventional smallpox vaccine). This announcement does not change ...

AlphaVax Continues to Expand the Use of Its Vaccine Platform

... a second grant to continue development of a smallpox vaccine based on AlphaVax's proprietary vector ... first grant period demonstrated that AlphaVax's smallpox vaccine, which expresses four, highly ... working with the U.S. Government to advance a new smallpox vaccine that has an excellent safety profile and ...

Chimerix Initiates a Multi-dose Clinical Trial of the Company's Lead Compound, CMX001, for the Treatment for Smallpox Infection

... drug candidate, CMX001, an oral treatment for smallpox infection. This trial will study the ... CMX001 is being developed for the treatment of smallpox infection and other double stranded DNA virus ... healthy volunteers. CMX001 is being developed for smallpox under a licensing agreement with Gilead ...

Albemarle Optimizes Smallpox Drug Candidate for SIGA

... to provide scale-up and manufacturing services for ST-246, SIGA's leading smallpox antiviral candidate. Caused by the variola virus, smallpox is no longer found generally in the environment, but it is considered a ...

Aethlon Medical to Present at the 2009 RedChip Small-Cap Investor Conference on June 16, 2009

... Flu), the reconstructed 1918 influenza virus (r1918), West Nile virus (WNV), and Vaccinia and Monkeypox (MPV), which both serve as models for human smallpox infection. The studies were conducted with the assistance of researchers representing: The U.S. Army Medical Research Institute of Infectious ...

BN ImmunoTherapeutics Updates on Phase I/II Studies With Breast Cancer Vaccine

... Bavarian Nordic has ongoing contracts with the US government for the late-stage development and procurement of the company's third-generation smallpox vaccine, IMVAMUNE(R). Bavarian Nordic is listed on the OMX NASDAQ under the symbol BAVA. For more information, please visit: ...

BN ImmunoTherapeutics Starts Clinical Trials With Prostate Cancer Vaccine

... Bavarian Nordic has ongoing contracts with the US government for the late-stage development and procurement of the company's third-generation smallpox vaccine, IMVAMUNE(R). Bavarian Nordic is listed on the OMX Nordic Exchange Copenhagen under the symbol BAVA. For more information, please visit: ...

GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2007 Financial Results

... binding Ab. GeoVax studies in non-human primates clearly show this Ab correlates with protection. -- GeoVax vaccines use an attenuated smallpox vaccine to provide pulses of HIV proteins (antigen) to stimulate protective anti-AIDS vaccine responses. Pulses of antigen from the ...

GeoVax Labs, Inc. Third Quarter Financial Results and Operational Update

... binding Ab. GeoVax studies in non-human primates clearly show this Ab correlates with protection. * GeoVax vaccines use an attenuated smallpox vaccine to provide pulses of HIV proteins (antigen) to stimulate protective anti-AIDS vaccine responses. Pulses of antigen from the ...
Smallpox in Medical Definition

Artificial induction of immunity

... Contents 1 Variolation and smallpox 2 Vaccination 3 Germ theory ... Variolation and smallpox See main articles variolation and smallpox . Typical site of inoculation in ...

Anthrax Vaccine Immunization Program

... up to the 2003 invasion of Iraq , all military personnel were required to get anthrax vaccination [6] (in addition to their other vaccinations of smallpox and other diseases and viruses like Japanese encephalitis, Pneumococcal, Tetanus, among others [7] ). While some military personnel had ...
Smallpox in Medical Dictionary

Anthrax

... to treat it. anthrax botulism plague smallpox tularemia . What is anthrax ? Anthrax is a ... Women Exposed to Anthrax -- ... However, smallpox has resurfaced as a health concern in recent ... or virus es to cause illness and spread fear). smallpox and anthrax (a disease caused by the spores ...

Bioterrorism

... smallpox bioterrorism : The misuse of smallpox as an agent of bioterrorism . Bioterrorism ... groups are working with anthrax . However, smallpox has resurfaced as a health concern in recent ...

Contagious

... your support may never be more valuable. smallpox is contagious It spreads from person to person ... kills about 30% of unvaccinated persons. Should smallpox be reintroduced, it could spread throughout the ... ecthyma; ecthyma, contagious ; ... smallpox : Also known as variola, a highly contagious ...

Smallpox

... smallpox : Also known as variola, a highly contagious ... rash that left pock marks in its wake. smallpox vaccination is a relatively safe, effective preventative against smallpox . However, in a number of individuals, ...

Terrorism

... THE RISK OF TERRORISM It is conceivable that smallpox could be deliberately reintroduced into the population. smallpox could be released by aerosol, and it would ... remains very stable in aerosol form. However, smallpox has resurfaced as a health concern in recent ...

Vaccinations

... vaccinations of dogs in our country. The smallpox vaccine was given to most people until 1972, when the US decided to stop routine smallpox vaccinations . The vaccine was causing side effects and there was almost no risk of getting smallpox at this time. Vaccinations for pneumococcal ...

Vaccination

... - article Colds and flu - factsheet ... smallpox vaccination is a relatively safe, effective preventative against smallpox . However, in a number of individuals, smallpox vaccination can result in untoward effects and ...

Fetus

... bones, are clearly visible in the middle of the screen. Definition of smallpox vaccination of fetus smallpox vaccination of fetus : See Congenital vaccinia. Search All of ...

Immunity

... Jenner (1749-1823) exploited the fact that cowpox created immunity to smallpox to create a vaccine for smallpox . They have to-there's no other way for their immune system s to build ...

Rash

... , or it may be a symptom of a systemic disease like measles , smallpox , or scarlet fever . Rash - child under 2 years Alternative Names: ... from a few hours to several weeks and varies in size. The rash of smallpox initially consists of dark red papule s, especially on the forehead, ...

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Smallpox in Biological News

Study characterizes eczema patients most at risk for dangerous viral infections

... people at risk for serious complications of smallpox vaccinations, and point to defects in the skin ... herpeticum. Vaccinia virus, which is used in smallpox vaccinations, can also cause a serious and ... susceptible to this infection when they receive a smallpox vaccination. This situation could limit the ...

New study indicates smallpox vaccination effective for decades

... December 1, 2008 Although naturally occurring smallpox was eradicated in 1977, there is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. Under such circumstances, the supply of smallpox vaccine may be insufficient for universal ...

Most people believe smallpox not an extinct disease

... of medical science the eradication of smallpox from the world over 40 years ago. A poll ... disquieting overall was the level of ignorance of smallpox eradication. This disease killed 300-500 million ... Organization campaign, based on vaccination, smallpox was declared extinct in 1979. Scientists are ...

Poxvirus potency uncovered in new atomic map

... organism such as smallpox, cowpox and monkeypox. smallpox in particular has played a tragic role in human ... and 500 million deaths in the 20th Century. smallpox was declared officially eradicated in 1979, but ... remain a health threat. The damage that the smallpox virus has done to mankind is horrific and ...

New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed

... smallpox is older than thought, according to results of a ... had recently sequenced the genomes of the various smallpox strains, based on the repository it holds for the ... Organization (the worlds only other declared smallpox storehouse is in Russia). The disease was ...

Tips from the Journals of the American Society for Microbiology

... and Chemotherapy, 51. 8: 2765-2773). New smallpox Vaccine Candidates Demonstrate Superior Immune ... of an immune-enhancing protein into two new smallpox vaccine candidates elicited superior immune ... the declaration of global eradication of smallpox in 1979, vaccinations for the general public were ...

First genetically-engineered malaria vaccine to enter human trials

... approach to vaccine development using a weakened form of the whole organism that causes a particular disease has proven successful in eradicating smallpox and controlling diseases such as flu and polio. Professor Cowman said the research team, which includes Dr Matthew O'Neill and Dr Alex Maier from ...

A card-swipe for medical tests

... be taken into the field, where a sample card or stick "could be dipped in groundwater, dried off and read in our device to look for E. coli, plague, smallpox or other suspects on the homeland security list," he says. Granger says cards with GMR sensors also could be used for environmental monitoring of ...

Potatoes may hold key to Alzheimer's treatment

... to make Alzheimer's vaccinations safer would be to use a closely-related, but not human, protein as the vaccine, much like cowpox virus is used for smallpox immunizations. In the August 15 Journal of Biological Chemistry, Robert Friedland and colleagues used this concept on an amyloid-like protein ...

LIAI researchers discover new cellular mechanism that will significantly advance vaccine development

... vaccine expert and director of the LIAI Center for Infectious Disease, also was a key contributor on the study. Dr. Crotty said the team studied the smallpox vaccine, considered the "gold standard" of vaccines, and found some startling answers. "We expected one thing based on textbook knowledge and that ...

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Smallpox in Biological Technology

New study indicates smallpox vaccination effective for decades

... December 1, 2008 Although naturally occurring smallpox was eradicated in 1977, there is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. Under such circumstances, the supply of smallpox vaccine may be insufficient for universal ...

Bavarian Nordic Has Essentially Agreed a Pathway for the Licensure of IMVAMUNE(R) With the FDA After Successful End of Phase II Meeting

... development of IMVAMUNE(R), a third-generation smallpox vaccine, Bavarian Nordic has held an end of ... the efficacy of products for indications like smallpox to be established in suitable animal efficacy ... is comparable to that induced by traditional smallpox vaccines. However, the efficacy of IMVAMUNE(R) ...

New study indicates smallpox vaccination effective for decades

... December 1, 2008 Although naturally occurring smallpox was eradicated in 1977, there is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. Under such circumstances, the supply of smallpox vaccine may be insufficient for universal ...

Bavarian Nordic A/S - Interim Report for the Period 1 January to 30 June 2008

... Biodefense IMVAMUNE(R) - third generation smallpox vaccine To-date, more than 1,900 subjects have ... subjects with a previous exposure to conventional smallpox vaccine was added to this study during the first ... that is contraindicated for traditional smallpox vaccines. The phase II study in patients ...

Nanoemulsion vaccines show increasing promise

... able to produce a strong immune response against smallpox and HIV in two new studies. The results build ... diverse materials. We used whole virus in the smallpox vaccine. In the HIV vaccine, we used a single ... and hepatitis B. Potential for a better smallpox vaccine ...

Bavarian Nordic Update - 2007 Annual Results, IMVAMUNE(R) Delivery Contract, Strategy Process

... million doses of the company's third-generation smallpox vaccine, IMVAMUNE(R), the contract includes an ... below, contracts with other countries for smallpox vaccines are not included in the guidance for ... Status Next milestone Biodefense smallpox (IMVAMUNE(R)) Phase II Phase III (2009) ...

Nasal Vaccine for Smallpox Confers High Levels of Immunity Without Safety Risks

... for smallpox. Vaccinia virus is related to smallpox virus and builds immunity against it. The new ... immune response without the potential risks of smallpox vaccination that are no longer considered ... first to demonstrate protective immunity against smallpox using a vaccine with inactivated virus, said ...

Government Expands Trial With IMVAMUNE(R) Smallpox Vaccine in Persons With Atopic Dermatitis/Eczema

... adverse reactions associated with traditional smallpox vaccines. This is an important step in our ... In 2004, the company expanded its IMVAMUNE smallpox vaccine program to include persons diagnosed with ... dermatitis. Atopic Dermatitis Prevalence and smallpox Vaccination A review by medical specialists ...

Bavarian Nordic Receives $50 Million Advance Payment from HHS for Fulfilling Contract Milestones

... 20 million doses of the company's, IMVAMUNE(R) smallpox vaccine. HHS approved the advance payment ... guidance for the company's 2007 result. IMVAMUNE smallpox vaccine contract In June 2007, HHS awarded ... and deliver IMVAMUNE, a next-generation smallpox vaccine to the strategic national stockpile. The ...

Tips from the Journals of the American Society for Microbiology

... and Chemotherapy, 51. 8: 2765-2773). New smallpox Vaccine Candidates Demonstrate Superior Immune ... of an immune-enhancing protein into two new smallpox vaccine candidates elicited superior immune ... the declaration of global eradication of smallpox in 1979, vaccinations for the general public were ...
Smallpox in Biological Definition

Edward Jenner

... , England , famous for his work introducing the smallpox vaccine . Jenner's early education included ... achievements. In Jenner's time, the practice of smallpox inoculation was commonplace in England. However ... ' cowpox ' protected one from contracting smallpox . (It has been theorized that the romantic image ...

Louis Pasteur

... not new: this had been known for a long time for smallpox . Inoculation with smallpox was known to result in far less scarring and ... this had generally replaced the use of actual smallpox material in inoculation. The difference with ...

Virus

... by any one of a variety of related viruses; smallpox ; AIDS , which is caused by HIV ; and cold ... in a laboratory. Much concern revolves around the smallpox virus, which has devastated numerous societies ... and today is extinct in the wild. In fact, smallpox has been used in a crude form of biological ...

Vaccine

... , which, when administered to humans, provided them protection against smallpox . Contents showTocToggle("show","hide") 1 Types of ... to vast numbers. Vaccines have contributed to the eradication of smallpox , one of the most contagious and deadly diseases known to man. Other ...

Outbreak

... pandemic (a global epidemic). Major human epidemic viruses include influenza , Human Immunodeficiancy Virus ( HIV ), measles , and rubella . smallpox has been eradicated as a major epidemic virus, however emerging viruses and engineered viruses pose a significant challenge for the future. HIV is ...

Virus classification

... Family Plasmaviridae Family Polyomaviridae - e.g. Simian virus 40 Family Poxviridae - e.g. Cowpox virus , Variola virus ( smallpox ) Family Rudiviridae Family Tectiviridae Unassigned genera Mimivirus ; type species: Acanthamoeba polyphaga mimivirus ...

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Smallpox in Biological Dictionary

Synapton

... Genetics and Physics of Complex System, Weizmann ... Horesh O, Simchen G, Friedmann A: Morphogenesis of the synapton during yeast meiosis. ... smallpox Vaccine, Vaccinia Vaccine. Snap Back® Sodium Bicarbonate ... Synagis™ Synalar® Synalgos®-DC. Synapton ® Synemol® Synercid® Synthroid® Syntocinon® ......

Mycelium

... Talks Mycologist Paul Stamets lists 6 ways the mycelium fungus can help save the universe: cleaning polluted soil, making insecticides, treating smallpox and ... ... Suppliers. Find a reliable & professional Mycelium manufacturer or supplier. ... Mushroom Extract and Mycelium Powder ... ...
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