Simplex

Test Before Corneal Transplant May Improve Outcome

... 1 (HealthDay News) -- Among patients with herpes simplex virus who need a corneal transplant, testing for ... light for vision, can be damaged when herpes simplex virus infects the eye. In some cases, the damage ... were more likely to fail in patients with herpes simplex virus infection than in those with other eye ...

Simplex Diabetic Supply Changes Its Name to Simplex Healthcare

... simplex Diabetic Supply today announced that after only 20 months it is retiring the name simplex Diabetic Supply and will now officially be known as simplex Healthcare. Nashville, ...

Herpes: Scientists find cellular process that fights virus

... virus responsible for cold sores: Type 1 herpes simplex (HSV-1). As reported in the advance online ... of an infected cell can unmask Type 1 herpes simplex and stimulate the immune system to disintegrate ... They replicated environments when Type 1 herpes simplex thrives, namely periods of low-grade fever ...

New Hope Against the Cold Sore Virus

... Driving herpes simplex out of hiding could bring about a cure, ... of unsightly cold sores, caused by the herpes simplex 1 virus, but new research is finally offering ... say they've unlocked the mystery of how herpes simplex 1 slips into dormancy and stays dormant -- ...

Study finds genetic link to human herpes susceptibility

... probability that people who are prone to herpes simplex virus (HSV) outbreaks can inherit that ... online now. There are two types of the herpes simplex virus. Type 1 (HSV-1) is responsible for the vast ... sore at some point during their lives. Herpes simplex virus type 2 (HSV-2) is the primary cause of ...

Simplex Diabetic Supply, Inc. Secures $50 Million in Growth Equity from New Enterprise Associates

... BRENTWOOD, Tenn., Oct. 8 /PRNewswire/ -- simplex Diabetic Supply, Inc. (Simplex) has secured a ... Chip Linehan and Ryan Drant will join the simplex Board of Directors. "NEA shares our vision for ... enough to be classified as diabetes. About simplex ...

More>>

Simplex in Medical Technology

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... In prior tests involving L.E.A.P.S. herpes simplex vaccines, CEL-SCI and other researchers showed ... a good indicator for protection against herpes simplex as well. Dr. Borthakur, of the University of ... from a disease-related protein, such as a herpes simplex virus (HSV) glycoprotein to make a vaccine that ...

Topical Treatment for Cold Sores Achieves Efficacy of Oral Drugs; Represents Paradigm Shift in the Treatment of Skin Infections

... in the dermis and epidermis, where it surrounds and fuses with herpes simplex virus and disrupts the outer envelope of the pathogen," Flack said. ... so it is not absorbed into the bloodstream." Because the herpes simplex virus causes both cold sores and genital herpes, there is a strong ...

AlphaVax Announces Results from Initial Testing of Its H1N1 (Swine) Influenza Vaccine

... a mixture of in-house and partnered programs. The AlphaVax technology is currently being used to advance vaccines for cytomegalovirus, herpes simplex virus, respiratory syncytial virus, a range of cancers, influenza, HIV and a number of biodefense targets. The AlphaVax headquarters and R&D ...

AlphaVax Announces Promising Results in Melanoma Studies

... clinical trial is planned for later this year. In addition to cancer immunotherapy programs, AlphaVax is developing vaccine products for herpes simplex virus, influenza, respiratory syncytial virus, HIV and a number of biodefense targets. The AlphaVax headquarters and R&D facilities are located ...

Indevus Pharmaceuticals Announces PRO 2000 Found to Show Promise in Large HIV Prevention Study

... the sexual transmission of HIV and other sexually transmitted diseases. Laboratory studies have shown that PRO 2000 is active against HIV, herpes simplex virus, chlamydia and the bacterium that causes gonorrhea. Vaginally applied PRO 2000 has been found to afford protection in mouse models for genital ...

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

... develop and market ganciclovir ophthalmic gel, available in Europe for the treatment of ocular viral infections for more than 10 years. Herpes simplex keratitis is the leading cause of corneal blindness in the US, with 20,000 new primary cases of diagnosed each year and an additional 28,000 cases of ...

More>>

Simplex in Medical Products

ImmunoDOT TORCH Test

Description:... immunoassay (EIA) procedure intended for determining the presence of antibodies to Toxoplasma gondii, rubella virus, cytomegalovirus and herpes simplex virus in serum and heparinized whole blood to indicate previous or current infection by these ....
Company:GenBio

biokitHSV-2 Rapid Test

Description:... either in heparinized capillary whole blood taken by fingerstick or in serum, of circulating IgG antibodies specific for herpes simplex virus type 2 (HSV-2), which arise as a result of infection with HSV-2. It is intended for in-vitro diagnostic use by health professionals ...
Company:Biokit

HSV Group IgG ELISA

Description:... Herpes simplex Virus Group ....
Company:Wampole Laboratories

HSV 2 IgG II ELISA

Description:... Herpes simplex Virus 2 IgG ....
Company:Wampole Laboratories

HSV 1 IgG II ELISA

Description:... Herpes simplex Virus 1 IgG ....
Company:Wampole Laboratories

Pathfinder HSV 1 and 2 DFA

Description:... The Pathfinder HSV 1 and 2 kit provides direct antigen detection and differentiation of Herpes simplex Virus (HSV) Types 1 and 2. The monoclonal antibody-based test can be used to directly stain clinical specimens or tissue culture ....
Company:Bio-Rad Laboratories

More>>

Simplex in Medical Dictionary

Chancroid

... than women are. Chancroid . Herpes simplex virus . Any bacterial infection that causes ... the skin of the genital s. Genital herpes simplex Syphilis , primary and syphilis , secondary ... Behcet's disease ... Genital herpes simplex Primary syphilis and secondary syphilis ...

Cold sore

... with. Cold sore s are caused by the herpes simplex virus , and they're contagious . More on Cold Sore Herpes simplex - an acute viral infection of the skin ... fluid. It is caused by either of two herpes simplex virus es: Type 1, herpes labialis , ... ...

Cold

... of the herpes virus family, called herpes simplex . They occur on the lip, or just above or below ... blister s around the mouth, caused by the herpes simplex virus . The most common strain of the virus is herpes simplex virus 1. Common Cold What is the ...

Cold sores

... of the herpes virus family, called herpes simplex . They occur on the lip, or just above or below ... blister s around the mouth, caused by the herpes simplex virus . The most common strain of the virus is herpes simplex virus 1. Cold sores - also called fever ...

Fever Blister

... blister s or cold sores are caused by herpes simplex virus type 1 and are very contagious . ... Migraines ... More on Fever Blister Herpes simplex - an acute viral infection of the skin ... fluid. It is caused by either of two herpes simplex virus es: Type 1, herpes labialis , ... ...

Genital Herpes

... ) is a viral infection caused by the herpes simplex virus (HSV). It is a sexually transmitted ... by a virus . The virus is called the herpes simplex virus , or HSV. It causes painful blister s ... vagina or on the penis . Genital herpes simplex Primary syphilis and secondary syphilis ...

More>>

Simplex in Biological News

Study characterizes eczema patients most at risk for dangerous viral infections

... patients who have suffered widespread herpes simplex viral infections of their skin. It is also the ... to widespread infections of their skin by herpes simplex and vaccinia viruses. The herpes simplex virus is common but only rarely causes ...

Rutgers Genetics receives $7.8 million for autism research

... that have a single autistic child. The Simons simplex Collection, as this project is known, will ... research and potential therapies. The Simons simplex Collection will supply the groundwork for a ... and scientists working with the Simons simplex Collection are establishing new and rigorous ...

Nanoemulsion potent against superbugs that kill cystic fibrosis patients

... already proved to be non-toxic, potent killers of bacteria such as Streptococcus pneumoniae, H. influenzae and gonorrhea, of viruses such as herpes simplex and influenza A, and of several fungi. Nanoemulsion treatments for cold sores and toenail fungus are in Phase 3 clinical trials. "We have a ...

Potential new herpes therapy studied

... another weapon for the fight against herpes. The gene-targeting approach uses a specially designed RNA enzyme to inhibit strains of the herpes simplex virus. The enzyme disables a gene responsible for producing a protein involved in the maturation and release of viral particles in an infected cell. ...

Life Sciences Discovery Fund awards health research program grants

... product planning. Three specific vaccine projects will be initially addressed. One in five adults in Washington State is infected with the herpes simplex virus (HSV)-2. Infectious syphilis cases have doubled in the United States since 2000 and E. coli contamination continues to be a persistent problem ...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

... response. Researchers have found that PS is exposed on the outer membrane of cells infected with HIV, influenza (including avian flu), herpes simplex viruses, hemorrhagic fever viruses, measles and members of the small pox and rabies virus families. Dr. Barton Haynes, director of Duke ...

More>>

Simplex in Biological Technology

Sirion Therapeutics New Drug Application for Ganciclovir is Accepted for Review by the FDA for the Treatment of Ocular Herpes

... keratitis, an ocular disease caused by the herpes simplex virus. The FDA has issued an action date in late ... ) "Herpes simplex keratitis remains one of the leading causes of ... About Herpetic Keratitis Herpes simplex virus (HSV) infections are very common, with ...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... that result initiate a protective cell mediated and antibody immune response. These results were obtained for L.E.A.P.S. vaccines against herpes simplex and HIV. The L.E.A.P.S. technology is a novel T-cell modulation platform technology that enables CEL-SCI to design and synthesize proprietary ...

CEL-SCI Developing Immune-Based Treatment Against Swine and Other H1N1 Flu Viruses Using Proprietary L.E.A.P.S. Technology

... several different L.E.A.P.S. conjugates induced protection and/or improvement in diseases as diverse as rheumatoid arthritis, malaria, TB and herpes simplex viruses. This shows that the L.E.A.P.S. technology can be successfully applied to many different diseases and these results further suggest that ....

China Sky One Medical, Inc. Obtains Production Approval for Two New Drugs

... in China for two of its newly developed drugs. Acyclovir gel is used to treat the skin infection due to varicella-zoster virus and the herpes simplex virus. Shuanghuanglian suppositories helps relieve cold and flu symptoms such as fever, cough and sore throat pain. It can also be used to treat ...

LaVoie Group Selected by Vaccine Developer, Profectus BioSciences, as Agency of Record

... Profectus' broad product pipeline will address Human Immunodeficiency Virus (HIV), Hepatitis C Virus (HCV), Human Papilloma Virus (HPV) and Herpes simplex Virus (HSV). The Profectus portfolio has received over $100 million in funding from multiple sources including National Institutes of Health ...

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

... L.E.A.P.S. technology combines a small peptide that activates the immune system with a small peptide from a disease-related protein, such as a herpes simplex virus (HSV) glycoprotein, to make a vaccine that induces a defined immune response. The Company hopes to commence clinical trials in humans in order ...

More>>

Simplex in Biological Products

Chicken Anti-DCTD (dCMP deaminase) Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description:... Fungi; Lymphoma; Myelogenous Leukemia; Pregnancy; Herpesviruses; Adenocarcinoma; Liver Cancer; Lung Cancer; Lung Tumor; Lung Diseases; Herpes simplex Virus; Epidermoid Carcinoma; Squamous Cell Car Protein Functions: Protein Byiosynthesis; Phosphotransferases; Pyrimidine Metabolism; One-Carbon ...
Company:GenWay Biotech, Inc.

Mouse Anti-Herpes Simplex Virus 1 HSV-1 gE Envelope Protein Monoclonal Antibody, Unconjugated, Clone 9H3 from Santa Cruz Biotechnology, Inc.

Description: HSV-1 gE Envelope Protein ...
Company:Santa Cruz Biotechnology, Inc.

Simplex in Biological Definition

Varicella zoster virus

... post-herpetic neuralgia , zoster multiplex, myelitis, herpes ophthalmicus, or zoster sine herpete. VZV is closely related to the herpes simplex viruses (HSV), sharing much genome homology. The known envelope glycoproteins (gB, gC, gE, gH, gI, gK, gL) correspond with those in HSV, however ...

Virus

... which is caused by any one of a variety of related viruses; smallpox ; AIDS , which is caused by HIV ; and cold sores, which are caused by herpes simplex . Recently it has been shown that cervical cancer is caused at least partly by papillomavirus (which causes papillomas, or warts), representing ...

Simplex in Biological Dictionary

DNA virus

... families that infect and may cause significant ... Hepatitis B is another small DNA virus that infects the liver, causes hepatitis, ... Herpes simplex virus (HSV) type 1 DNA synthesis and packaging occur within the ... Levels of DNA replication in the wild-type virus were also quite low ...

Complementation test

... interests, social connections, and funding of leading scientists Qualitative complementation test for temperature-sensitive mutants of herpes simplex virus. ... test reflects the ability of mutant pairs to interact by both ... complementation synonyms, complementation antonyms. Information ...