Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
..., this germ binds to pIgR and pushes this antibody shuttle backthrough the cell to the bloodstream. Once at the other side of thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancel...New comparative toxicogenomics database
..., this germ binds to pIgR and pushes this antibody shuttle backthrough the cell to the bloodstream. Once at the other side of thecell, the pneumococcus breaks free of pIgR and enters the blood, whereit can multiply and infect the body. S. pneumoniae is the only bacterium known to use CbpA to invade humancel...Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows
...ght on the tiny movements of molecular motors that shuttle material within living cells. The motors cooperate in a delicate choreography of steps, rather than engaging in the brute-force tug of war many scientists had imagined. "We discovered that two molecular motors -- dynein and kinesin -- do not compet...Motor transport in bio-nano systems
... cell center to the periphery and vice versa, some shuttle between different organelles or cellular compartments. An extreme case is provided by the long-ranged transport of vesicles and organelles along the axons between our nerve cells, which can be as long as half a meter. All of these movements are based...No small feat: First ever gene therapy success for muscular dystrophy achieved
...e viral vectors ?disarmed viruses that are used to shuttle genes into cells. But the team found a good stand-in in a similar protein called agrin that when miniaturized could be inserted inside an adeno-associated virus (AAV) vector. Dr. Xiao's laboratory is known for its work developing this vector, which t...A Positive Selection Assay for Mutation Analysis in Big Blue Animals
...nsgenic rodents harbor the Big Blue l LIZ shuttle vector ( figure 1 ), which can easily be r...ne from E. coli, located within the l LIZ shuttle vector, functions as a mutational test sequence. Rescued shuttle vector phage containing lac......siredexpression cassette is first subcloned into a shuttle vector, then transferredinto the adenoviral genome...method involves cloning the gene of interestinto a shuttle vector and transferring the gene into the adenovirus genome bymeans of homologous recombination in v...Big Blue Rodent Cell Cultures for Mutagenesis Studies
... cell line transfected with the Big Blue lambda shuttle vector and the pSV2Neo plasmid, which prov...selection marker. 5-7 The Big Blue lambda shuttle vector ( figure 1 ) is 45 kb in size and contains the lacI and alphalacZ genes. Each ...New Protocols for Isolating High- Molecular-Weight Genomic DNA
... mutation assays is retrieving large quantities of shuttle vector from theanimals genomic DNA for subsequent ...mutations within a targetregion of the vector. The shuttle vector in Big Blue was derived frombacteriophage lambda and can be retrieved from the animal by subj...Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer
...transgene in a retrievablechromosomally integrated shuttle vector, it is easy to study mutations in maleand f... gene. The lacI gene, part of the l LIZ shuttle vector, is present in approximately 40 copies per chromosome in the mouse and rat. Mutations...Blood Donation is the most priceless gift
...ood. The Program coordinator as agreed to organize shuttle bus service between their office and blood donation bank and this program will provide a free health checkup apart from blood testing which involves testing for HIV, Hepatitis Virus, Treponema bacteria, West Nile Virus and other blood transmitting di...Effect of Prolonged Stay in Space Studied Using Fruit Flies
...eagues will test the flies for two weeks after the shuttle returns. Scientists from NASA's Ames Research C...development of humans, he said. The flies on the shuttle will travel in 10 small containers, each of which is about the size of a computer zip disk. Two sepa...Experiments In Outer Space To Determine single Cell Survival
...death upon drying. Already launched on the space shuttle The incorporated cells of the Brinker group are ... on the recently completed mission of the US space shuttle Discovery. On the Space Station, experiments will be performed to determine their longevity when exp......hich is related to a large family of proteins that shuttle ions into and out of cells. As predicted for a candidate sour receptor, PKD2L1 was not found in the cells that express the receptors for sweet, bitter, and umami, but instead was found in a novel population of taste cells. "Our fundamental premise wa...Resort Mello Rosa Teams Up With Ayurvedic Natural Health Center
...a large pool deck and terrace sun decks and a free shuttle bus to and from the beach. The resort's excellent location provides the perfect surroundings for relaxation. It is situated 15km (9m) from Panjim, 40km (25m) from the airport, 15km (9m) from the railway station and 7km (4m) from Mapusa, the nearest...