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Sequence in Medical News

GeneGo Awarded NIH Grant to Develop Pharmacogenomics Software Suite

... designed for the study of mutations and sequence heterogeneity in human genes and their ... as well as the biological consequences of sequence variations on disease susceptibility and drug ... tools for researchers to be able to link these sequence variations to the specific mechanisms and ...

Arizona researchers to sequence West African rice strain

... took part in a six-year, $200 million project to sequence the genome of Asian cultivated rice. Now, new ... and Rounsley have developed will allow them to sequence West African rice in only six months at a ... use Wing and Rounsley's sequencing technique to sequence other rice relatives as well. They, as well as ...

Intradigm Announces Issuance of RNA Interference (RNAi) Patent Covering Potent siRNA Sequence

... Intradigm's Large Collection of Pending siRNA sequence Patents PALO ALTO, Calif., May 19 ... patent covers a specific double-stranded siRNA sequence that is directed against the angiogenic pathway ... regarding the potential of Intradigm's siRNA sequence IP is particularly gratifying," said Mike Riley, ...

Mayo clinic study finds gene bringing together animal and human research in alcoholism

... of clinical and basic scientists investigated the sequence of the human MPDZ gene and its association with ... withdrawal. Unfortunately, little was known about sequence variability of the MPDZ gene in humans. It is ... showed no significant association between MPDZ sequence variants and withdrawal seizures in humans. This ...

Mayo Clinic Study Finds Gene Bringing Together Animal and Human Research in Alcoholism

... of clinical and basic scientists investigated the sequence of the human MPDZ gene and its association with ... withdrawal. Unfortunately, little was known about sequence variability of the MPDZ gene in humans. It is ... showed no significant association between MPDZ sequence variants and withdrawal seizures in humans. This ...

Scientists From 25 Countries Sequence Cow Genome

... Taylor said. In fact, the cow gene sequence and the chromosomal arrangements are more similar ... we may be better off looking at the cow sequence for a lot of functions we study in mice and ... "Those could be mistakes in the human genome sequence but a more interesting possibility is that those ...

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Sequence in Medical Technology

Raptor Pharmaceuticals Provides Update on Targeting Platforms

... with Brigham and Women's Hospital focuses on RAP sequence variants engineered for improved binding affinity ... and researchers at Raptor will test RAP sequence variants designed to withstand temperatures, pH ... Blacklow's lab to develop effective RAP-based sequence variants that could increase the utility of ...

Panacea Pharmaceuticals Announces Issuance of a U.S. Patent Covering Anti-HAAH Antibodies

... Panacea is developing PAN-622, an all-human sequence anti-HAAH monoclonal antibody covered under this ... the efficacy of PAN-622, an all-human sequence anti-HAAH monoclonal antibody, in animal models ... Institute of Technology. "PAN-622 as an all-human sequence monoclonal antibody is particularly exciting, and ...

Microarray Sequence Capture Speeds Large-Scale Resequencing of Targeted Genomic Regions

... In light of the success of the current sequence capture technology, Baylor's Human Genome ... as an early access customer to Roche NimbleGen's sequence capture technology. As presented on October 10, ... PCR is limited in the length of sequence it can amplify, is difficult to scale or ...

NOVAVAX Achieves Pandemic H1N1 Influenza Production Milestone

... This milestone was accomplished in only 11 weeks after receiving the gene sequence for the H1N1 strain from the U.S. Centers for Disease Control. The ... countries. A detailed timeline describing the process from gene sequence to cGMP manufacturing is available on the Novavax website ...

AlphaVax Announces Results from Initial Testing of Its H1N1 (Swine) Influenza Vaccine

... The studies performed at AlphaVax utilized the California 04/2009 HA sequence obtained from the WHO GISAID database on April 25th. Mice inoculated with ... which is less than three full months from our initial receipt of the gene sequence from the WHO. We are currently scaling up the process used to manufacture ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... ( www.replikins.com ) last week analyzed the most recent peptide genomic sequence data available and determined that the infectivity of the H1N1 virus will ... future. The company's quantitative analysis of the most recent sequence data available on PubMed, a standard scientific repository for published ...

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Sequence in Medical Products

ABI PRISM Optical Adhesive Cover Starter Kit

Description:... set of guidelines to ensure success when using sequence detection systems (SDS) reagents and ... plastic consumables designed and optimized for sequence detection systems instrumentation. All consumable ... can be used with ABI PRISM 7700 and GeneAmp 5700 sequence Detection Systems. Optical Tubes are offered in ...
Company:Applied Biosystems

ABI PRISM Optical Adhesive Covers

Description:... set of guidelines to ensure success when using sequence detection systems (SDS) reagents and ... plastic consumables designed and optimized for sequence detection systems instrumentation. All consumable ... can be used with ABI PRISM 7700 and GeneAmp 5700 sequence Detection Systems. Optical Tubes are offered in ...
Company:Applied Biosystems

C6 B. burgdorferi (Lyme) ELISA Kit

Description:... This ELISA is based on the C6 peptide antigen, a 26 amino acid sequence of the surface protein VlsE. This peptide has been shown to represent the ... of Lyme disease. As the C6 antigen represents a defined sequence within the protein, cross-reactivity with antigens found in other ...
Company:Immunetics, Inc.

Impact2 EXP 8-Channel Electronic Pipettor, 0.5-12.5L

Description:... supernatant collections or other procedures individually or programmed in sequence according to protocol. Turn the pipettor off and it automatically remembers your most recent sequence the next time you turn it on. Simple Calibration In-lab calibration can ...
Company:Matrix Technologies Corporation

Impact2 EXP 8-Channel Electronic Pipettor, 15-1250L

Description:... supernatant collections or other procedures individually or programmed in sequence according to protocol. Turn the pipettor off and it automatically remembers your most recent sequence the next time you turn it on. Simple Calibration In-lab calibration can ...
Company:Matrix Technologies Corporation

Impact2 EXP 8-Channel Electronic Pipettor, 5-250L

Description:... supernatant collections or other procedures individually or programmed in sequence according to protocol. Turn the pipettor off and it automatically remembers your most recent sequence the next time you turn it on. Simple Calibration In-lab calibration can ...
Company:Matrix Technologies Corporation

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Sequence in Medical Definition

Nuclear medicine

... images. In multi-image datasets the array of images may represent a time sequence (ie. cine or movie) often called a "dynamic" dataset, a cardiac gated time sequence, or a spatial sequence where the gamma-camera is moved relative to the patient. SPECT (single ...

Artificial induction of immunity

... of immunity will translate to improved clinical practice in the future. This article places the development of techniques in historical and logical sequence and points to detailed articles on each of the main topics. Contents 1 Variolation and smallpox 2 Vaccination 3 ...

Breath-holding spells

... the child is not having a spell is still generally normal. The diagnosis of a breath holding spell is made clinically. A good history including the sequence of events, lack of incontinence and no post ictal phase, help to make an accurate diagnosis. Some families are advised to tape the events to aid ...

Proteopathy

... proteopathic diseases augment the tendency of vulnerable proteins to self-assemble. They include destabilizing changes in the primary amino acid sequence of the protein, post-translational modifications (such as hyperphosphorylation ), changes in temperature or pH, an increase in production of a ...

Thymocyte

... During the double negative stage the major maturation step of thymocytes is to express a T cell receptor . Unlike most genes, which have a stable sequence in each cell which expresses them, the T cell receptor is made up of a series of alternative gene fragments. In order to create a functional T cell ...

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Sequence in Medical Dictionary

Acid

... s. Amino acid : One of the 20 building blocks of protein . The sequence of amino acid s in a protein and, hence, the function of that ... Vibriosis. We will synthesize molecules that bear the amino acid sequence (i.e. TVGYG and mutation s) responsible for the selection of the K+ ions ...

Body weight

... common of these. Other documented effects of GHB include amnesia and hypotonia (associated with doses of 10 mg/kg body weight ); a normal sequence of rapid eye movement ( REM ) and non- REM sleep (doses of 20-30 mg/kg body weight ); ... Successful treatment involves exercise , rest, ...

Compartment syndrome

... to flatten excessively. Compartment syndrome Compassionate use Complement system Complement ary DNA Complement ary medicine Complement ary sequence Complete androgen insensitivity syndrome Complete blood count Complete hysterectomy Complete syndactyly ... Compartment Syndrome ...

Complement

... or instead of (alternative) standard treatment s. These practices are not considered standard medical approaches. COMPLEMENT CASCADE: A precise sequence of events, usually triggered by an antigen - antibody complex, in which each component of the complement system is activated in turn. See ...

Fertilization

... self- fertilization may occur between two proglottids of the same worm, or within the same proglottid. Pregnancy ought to be a very natural sequence of events from the fertilization of the egg to giving birth , however, it can often be a very stress ful and anxious time during which the woman ...

Heart

... is the tube that carries food from your throat to your stomach . Heart murmurs Dr Trisha Macnair The heart normally makes a recognisable sequence of sounds as blood is pumped through its chambers and valves open and close. Heart bypass surgery - series Illustrations: In many cases, ...

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Sequence in Biological News

Understanding how weeds are resistant to herbicides

... in the Keck Center at the U of I. The genetic sequence will allow scientists to study herbicide ... of having the genetic data. "Once we obtain the sequence of a resistance gene, we can develop molecular ... it is resistant or not because we know the gene sequence and we know the mutation and the mechanism." ...

ISU researchers find possible treatment for spinal muscular atrophy

... becomes mRNA by splicing out certain parts of the sequence that are non-coding, meaning they don't help the ... intronic sequences, sometimes referred to as junk sequence because it is originally copied from junk DNA. ... because of the presence of a specific intronic sequence in the gene or DNA. To make SMN2 behave as ...

Mystery E. coli genes essential for survival of many species

... the University of Dundee has examined the genome sequence of this workhorse of the laboratory and spotted ... Bacteriology . The effort over recent years to sequence genomes of various important species has ... work is a good example of where having a genome sequence opens up many possible avenues of enquiry. It ...

Landmark project to map genomics of complex ant systems

... Gerardo put together a project to not only sequence ant genomes for the first time, but also the ... species. Entering new territory Roche will sequence the DNA using its proprietary high-throughput ... millions of dollars and extensive manpower to sequence just one organism. "We're entering completely ...

Natural-born divers and the molecular traces of evolution

... pressure, they went on to study the molecular sequence of myoglobin in small aquatic mammals such as ... therefore it can be predicted if the amino acid sequence is known. Dr. Berenbrink's team have determined large parts of the myoglobin sequence for four different species of insectivores, and ...

CSHL scientists harness logic of 'Sudoku' math puzzle to vastly enhance genome-sequencing capability

... it is possible to use the Sudoku method to sequence more than a hundred thousand DNA samples," says ... as identification markers and thus tell which sequence belonged to which sample. "But this approach ... which pool contains which samples, we can link a sequence to an individual sample with high confidence," ...

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Sequence in Biological Technology

SmartGene's Services for Faster, More Precise Identification of Bacteria and Fungi to be Used by The Johns Hopkins Hospital

... of bacterial and fungal pathogens by sequence analysis. Some bacteria and fungi do not ... DNA, by integrating a number of tasks, including sequence editing, alignment, interpretation, creation of ... to manage and more fully utilize their genetic sequence data over time, completely independent of ...

First Catalog Cancer Biochip for Sequence Capture Now Available from febit

... febit's highly automated technology for sequence capture, enabling targeted Next-Generation ... results of the 100 most relevant genes with high sequence coverage using the HybSelect technique. It is ... in 2010. Multiplex NGS studies based on sequence capture can be supplemented by other molecular ...

febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment

... febit Technology Enables the Conversion of New sequence Data into Biochips for Gene Expression Profiling and sequence Capture for Next-Generation Sequencing Within ... efficient option for transforming digital genetic sequence information directly into a fully-applicable ...

DNA2.0 Awarded US Patents for Breakthrough Gene Optimization Technology -- Company's Unique Algorithm Enables Expression Yields up to 50 Times Greater than Competing Approaches

... DNA2.0 has cracked the code on optimizing sequence design and has been awarded two US patents ... expression by designing the most effective coding sequence is therefore essential. Despite the high value of sequence design, most currently used algorithms are based ...

MIT, BU engineer cellular circuits that count events

... the number of times a cell divides, or to study a sequence of developmental stages. They could also serve as ... RNA polymerase. The number of steps in the sequence is, in theory, limited only by the number of ... flips it over and re-inserts it, altering the sequence in a predictable way. The DIC Counter ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... week analyzed the most recent peptide genomic sequence data available and determined that the ... quantitative analysis of the most recent sequence data available on PubMed, a standard scientific ... week analyzed the most recent peptide genomic sequence data available and determined that the ...

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Sequence in Biological Products

Rabbit Anti-Human Connexin 36 Monoclonal Antibody,, Clone ZMD.257 from Invitrogen

Description:... of the human Connexin 36 protein This peptide sequence is downstream from the sequence used to generate another Zymed polyclonal ... brain retina and pancreas homogenates). Based on sequence homology reactivity with Human rat and zebrafish. ...
Company:Invitrogen

Gene Inspector™ 1.6 Demo (OS 10.2.x or later) from Textco, Inc.

Description:... but this software is much more than just another sequence analysis product. Imagine having the ability to ... and store analysis parameters for any DNA sequence analysis or protein sequence analysis to fit your needs, anyone in the lab ...
Company:Textco, Inc.

Expression from Genamics

Description:... revolutionary new application for DNA and protein sequence analysis. Utilising a novel interface, Expression makes complex computational analyses of sequence information incredibly simple. Expression uses ... the way sequences are analysed. Features include: sequence ...
Company:Genamics

Expression from Genamics

Description:... is a powerful application for DNA and protein sequence analysis. Utilising a novel interface, Expression makes complex computational analyses of sequence information incredibly simple. Expression uses ... the way sequences are analysed. Features include: sequence Annotation, Interactive ...
Company:Genamics

ENGENISTM siRNA Test System from Yorkshire Bioscience Ltd

Description:... approach for evaluation of a potential of any DNA sequence to serve as an efficient target for RNA ... not perfect, leaving the probability of selected sequence to be a good target from 30% to 60%. It is therefore clear that the ability of computer-selected sequence to induce RNA interference has to be confirmed ...
Company:Yorkshire Bioscience Ltd

CpG WIZ® DAP-KINASE AMPLIFICATION KIT from CHEMICON

Description:... modification. Chemical modification creates the sequence differences between the methylated and ... engineered to anneal to the DNA, based upon the sequence differences. U Primer Set will anneal to ... to 50%). The amplified region is defined as the sequence between the 3' nucleotide of the sense primer and ...
Company:CHEMICON

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Sequence in Biological Definition

Alternative splicing

... as a twofold information structure: A DNA sequence coding for the pre-mRNA An additional DNA code ... case, certain exons are spliced out to alter the sequence of amino acids in the expressed protein. ... genetics it means that the old idea of one DNA sequence coding for one polypeptide (the ...

Bioinformatics

... . Major research efforts in the field include sequence alignment , protein structure alignment , ... 1 Major research areas 1.1 sequence analysis 2 Computational evolutionary ... External links Major research areas sequence analysis Main articles: ...

Biopolymer

... acids . The exact chemical composition and the sequence in which these units are arranged is called the ... acid terminus. The convention for a nucleic acid sequence is to list the nucleotides as they occur from ... phosphate diester linkages of the chain. Such a sequence is called the primary structure of the ...

BLAST

... to look for sequences that resemble a given sequence of interest. For example, following the discovery ... in lineage to a certain protein whose amino-acid sequence I know? Where does the DNA that I've just ... part of other algorithms that require approximate sequence matching. The BLAST algorithm and a computer ...

Chromosome walking

... sequenced, this method works by dividing the long sequence into several consecutive short ones. The basic ... primer that matches the beginning of the DNA to sequence is used to synthesize a short DNA strand ... along the sequence. The method can be used to sequence entire chromosomes (thus, chromosome walking ). ...

Genetic code

... genetic code 4.3 Phase or reading frame of a sequence 5 Origin of the genetic code 6 ... will then be folded into a protein . The gene sequence inscribed in DNA, and in RNA, is composed of ... codon combinations. For example, the RNA sequence UUUAAACCC contains the codons UUU, AAA and CCC, ...

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Sequence in Biological Dictionary

TATA box

... The TATA box is a DNA sequence found in the promoter region of most genes in ... factor that binds specifically to a DNA sequence called the TATA box . This DNA sequence is found about 25-30 base pairs upstream of ...

Tandem repeat sequence

... in strings (e.g. DNA sequences ) can ... sequence . Tandem ... (Long terminal repeat , SINEs, LINEs) · Genomic island · Alu sequence ... A Variable Number Tandem Repeat (or ... in a genome where a short nucleotide sequence is organized as a tandem repeat . These can be ...

Tandem repeat sequences

... repeat , SINEs, LINEs) · Genomic island · Alu sequence ... A short tandem repeat (STR) in DNA ... : Multiple copies of the same DNA base sequence on ... ... Computer Science, tandem ... sequences ) can be ... A tandem repeat is a sequence of two or more approximate copies of a pattern. ....

Southern blotting

... biology for detection of a specific DNA sequence in DNA samples. Southern blotting combines ... of PCR products can validate that a given DNA sequence was PCR ... Southern Blot : Part 2. ... perform a Southern blot , using the probe sequence marked ABC, and get the ... " Southern ...

Single locus probe

... A single locus probe is a DNA or RNA sequence that is able to hybridize (i.e. ... has been ... probe in DNA fingerprint analysis? ... sequence just outside of the repeated structure, is termed ... . A single - locus probe is where the core sequence only occurs at one DNA locus and ... ...

Simple Sequence Repeat

... ... how many repeats of the STR sequence in question there ... ... repeat , SINEs, LINEs) · Genomic island · Alu sequence ... Microsatellites, or Simple sequence Repeats (SSRs), are polymorphic loci ...

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Breaking Biology News(10 mins):Continuing the quest for better stroke therapies 2Continuing the quest for better stroke therapies 3New method provides researchers with efficient tool for tagging proteins 2Counting down to FEBS-EMBO 2014 in Paris, France 2
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