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Sepsis in Medical News

Sepsis Treatment Offers Lifesaving Potential

... toxins from the blood of patients with severe sepsis or septic shock appears to improve blood ... The study included 64 patients with severe sepsis or septic shock who had emergency surgery for ... given the significant ongoing problem that sepsis represents," they wrote. More information ...

Vanderbilt researchers pioneer an advanced sepsis detection and management system

... The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and ... they believe is the first real-time system for sepsis detection. In May, the system was deployed in the ... physicians through the complex process of sepsis treatment. "This is an effort to use the power ...

Frost & Sullivan Award Reinforces Outstanding Product Line Strategy by SIRS-Lab

... GmbH. The company's exceptional product line for sepsis diagnosis and monitoring make it a worthy ... ) sepsis is the second commonest cause of death in ... care physicians is to be able to identify sepsis as early as possible to facilitate appropriate ...

Packard/Stanford study suggests two causes for bowel disease in infants

... infection of the abdominal cavity or blood sepsis as well as lasting consequences such as the need ... of young people." Learning how to heal the sepsis that results from necrotizing enterocolitis could help doctors get a better handle on sepsis cases in children and young adults. ...

Children's National Research Links Platelets to Sepsis-Related Organ Failure

... sinister role in organ failure caused by severe sepsis Washington, DC (Vocus) ... over the last few decades, mortality rates for sepsis have not really improved," said Robert ... in the United States. More than 40 percent of sepsis cases are fatal, and in most, the resulting organ ...

Sepsis Therapy in Preemies Fails to Boost Survival

... with blood cell growth factor fails to prevent sepsis or improve survival rates, a new study shows. ... consider if this is too simplistic an approach to sepsis prevention in the preterm infant, whose immune ... U.S. National Library of Medicine has more about sepsis . -- Kevin ...

Medical Simulation Corporation Introduces Sepsis Quality Initiative Program

... (MSC) announces the introduction of the SimSuite sepsis Program, based on guidelines developed by the national Surviving sepsis Campaign. The Sepsis Program is one offering in a ... and patient safety initiatives. Each year, sepsis strikes an estimated 750,000 people in the ...

Educational Drive Cut Death Rate From Sepsis

... in Spain to promote appropriate care for severe sepsis (bloodstream infection) and septic shock led to improved guideline adherence and a lower rate of sepsis deaths in hospitals, a new study says. Severe sepsis accounts for one in five admissions to intensive ...

Ashwell receptor reduces mortality during sepsis

... factors contributing to death in patients with sepsis is a condition called disseminated intravascular ... prevailing notion that the low platelet count of sepsis is due to the consumption of coagulation factors ... new way of thinking about coagulation problems in sepsis produced by pneumococcus and related pathogens ...

Customized treatments for sepsis lower treatment time and reduce length of ICU stays

... of antibiotic therapy in patients with severe sepsis or septic shock can reduce duration of ... ill patients admitted to the ICU for severe sepsis and septic shock, wrote Dr. Pugin. Despite the ... treatments will continue to improve care for sepsis patients around the world. We have now ...

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Sepsis in Medical Technology

Sirius Genomics Announces New Collaboration with Assistance Publique-Hopitaux de Paris

... (AP-HP) to study genomic correlations in severe sepsis patients. The agreement focuses on the continued ... the trademark Xigris (R)) in patients with severe sepsis at high risk of death. "Access to AP-HP's severe sepsis patients will be critical in the validation of ...

Agennix Initiates A Randomized Double-Blind, Placebo-Controlled Phase 2 Study of Oral Talactoferrin in Severe Sepsis

... is the first clinical trial of talactoferrin in sepsis and is based on both the mechanism of action of ... of deaths in patients with severe sepsis." sepsis is a clinical syndrome defined by the presence of ... cytokine surge induced by endotoxin. "Severe sepsis is a serious medical condition that is associated ...

Spectral presents data on the clinical utility of EAA(TM) at 13th Annual Critical Care for Endotoxemia conference in Japan

... product in the United States." Debra Foster, Director of Spectral's sepsis Program, presented data on the use of EAA(TM) in the management of intra-abdominal sepsis following surgical intervention. Following the conference, these findings ...

ERBITUX(R) Meets Primary Endpoint of Increasing Survival in Phase III Lung Cancer Study

... of severe dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure ... dermatologic toxicity (1%), interstitial lung disease (0.4%), fever (5%), sepsis (3%), kidney failure (2%), pulmonary embolus (1%), dehydration (5% in ...

Great Basin Scientific, Inc. Raises $3.6 Million in Bridge Funding to Prepare for Launch of First Product

... In addition to its first product for MRSA testing, the company is also developing tests for Group B Streptococcus - the most common cause of sepsis and meningitis in newborns, and Human Papilloma Virus (HPV), the most common sexually transmitted infection of which certain types can lead to ...

Two New Clinical Studies Show That Limited Exposure to Blood Transfusion Significantly Increases Morbidity and Mortality After Surgery

... transfusion of 1U to 2U of packed red blood cells is associated with increased 30-day mortality, surgical site infection, pneumonia, and sepsis in general surgery patients. Journal of the American College of Surgeons. 2009; 208:931-937. (2) Surgenor SD et al, for the Northern New ...

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

... with Valcyte, occurred in the 100-day treatment group and took place in France, Belgium and Romania. They were attributed to hemorrhage (one), sepsis (one) or septic shock (two). About CMV CMV belongs to the family of herpes viruses and, as such, is very common among the general ...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

... and/or VELCADE - Persistent severe myelosuppression may result in superinfection, neutropenic fever, or hemorrhage - sepsis occurring during neutropenia has resulted in discontinuation of treatment and in rare cases of death * DOXIL may potentiate the ...

Phase III Trial Results Show Elitek(R) (rasburicase) Significantly Reduced Plasma Uric Acid Levels versus Allopurinol in Adults with Hematologic Cancers at Risk for Tumor Lysis Syndrome

... 1% of which were Grade 3 or higher. The most common serious adverse reactions regardless of the relationship to the study drug were neutropenic sepsis (5.4% / 1.1% / 3.3%), neutropenic infection (5.4% / 4.3% / 8.8%), and febrile neutropenia (4.3% / 3.3% / 5.5%), pulmonary hemorrhage (1.1% / 3.3% / ...

Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA

... MRSA/SA BC processes positive blood culture specimens to determine if a patient's blood is infected with MRSA or SA, which are frequent causes of sepsis in hospitalized patients. This may enable physicians to quickly de-escalate from broad-spectrum antibiotic treatment to a more effective targeted ...

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Sepsis in Medical Dictionary

Sepsis

... sepsis is a term for severe infection that is present ... the body. In newborns, it is also called sepsis neonatorum or neonatal septicemia . What causes sepsis ? ...

Septicemia

... : The systemic disease associated with sepsis . Blood poisoning . Septicemia The presence ... the heart , and sores that do not heal. GBS sepsis (Group B Streptococcal Septicemia of the ... ), can rapidly become life-threatening. sepsis is a term for severe infection that is present ...

Acidosis

... . metabolic acidosis (met-ah-BOL-ik as-id-O-sis) A condition in which the blood is too acidic. It may be caused by severe illness or sepsis ( bacteria in the blood stream). metabolic disorder ... Heartburn ( Acidosis , Overacid Stomach ) Hiatal Hernia (Hiatus Hernia ) ...

Aging skin

... , such as radiation therapy and chemotherapy for cancer birth , due to the pressure changes caused by vagina l delivery aging skin sepsis , or blood infection violent vomiting or cough ing ... ...

Ammonia

... in the air, such as ammonia or hydrocarbons; or too much oxygen , which itself can injure the lungs . Infection by a virus or bacterium, or sepsis , a widespread infection that gets into the blood . Struvite stones - These stones are made of magnesium and ammonia (a waste product), and ...

Aspirin overdose

... , starvation , drinking an excessive amount of alcohol, or drinking antifreeze ( ethylene glycol ). infection such as pneumonia or sepsis cardiac disease such as congestive heart failure or heart attack severe pain bleeding drugs (such as an aspirin overdose ) ...

Bacteremia

... Capable of killing bacteria . BACTERIOSTATIC: Capable of inhibiting or slowing the reproduction of bacteria . Bacteremia with sepsis ( Septicemia ) Bacteremic Shock ( Septic Shock ) Bacterial Arthritis (Non-Gonococcal (Septic) Bacterial Arthritis ) Bacterial Diarrhea ...

Bacterial Infections

... susceptible to secondary bacterial infections . Disseminated intra vascular coagulation ( DIC ) can be caused by severe bacterial infections ( sepsis ), extensive burns , trauma , retained dead fetus , heat stroke , mismatched blood transfusion , metastatic cancer , and some forms of ...

Biliary atresia

... syndrome s) biliary atresia autoimmune hepatitis malaria ... Other factors which can potentiate jaundice in the newborn include: sepsis , biliary atresia , Rh incompatibility, galactosemia , cephalo hematoma , polycythemia , G-6-P-D deficiency , and congenital rubella , syphilis ...

Birth

... uterus . The fever is also called childbed fever or puerperal fever . If the infection involves the blood stream, it constitutes puerperal sepsis . Child birth usually begins spontaneously, following about 280 days after conception , but it may be started by artificial means if the ...

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Sepsis in Biological News

Older men more likely than women to die after pneumonia

... multicenter Genetic and Inflammatory Markers of sepsis (GenIMS) study. Participants were enrolled upon ... such as cardiac disease or cancer. Severe sepsis occurred in 588 (31 percent) subjects. Of these, about half had severe sepsis on their first day of hospitalization. Men ...

Children's National research links platelets to sepsis-related organ failure

... over the last few decades, mortality rates for sepsis have not really improved," said Robert ... of dying and to design new interventions." sepsis is the tenth leading cause of death in the United States. More than 40 percent of sepsis cases are fatal, and in most, the resulting organ ...

In the laboratory, green tea proves a powerful medicine against severe sepsis

... ingredient in green tea rescued mice from lethal sepsis and the findings could pave the way to clinical ... Wang had previously discovered a late mediator of sepsis called HMGB1, a substance expressed in the late ... which they felt would prevent the lethal sepsis process from moving forward. And it worked. ...

Study begins to reveal clues to the cause and progression of sepsis

... PITTSBURGH, Aug. 13 Not all patients with sepsis mount the same immune response, even when they ... and death. More than 30 percent will die, making sepsis the 10th leading cause of death. While incidence rates of sepsis have been steadily increasing over the years, ...

Scientists uncork a potential secret of red wine's health benefits

... and systemic sepsis. "Strong acute inflammatory diseases such as sepsis are very difficult to treat and many die every day due to lack of ... one of the researchers involved in the work. "Moreover, many survivors of sepsis develop a very low quality of life due to the damage that inflammation ...

Nature study demonstrates that bacterial clotting depends on clustering

... to new clinical methods for treating serious medical conditions such as sepsis and anthrax. It has long been known that blood often coagulates during sepsis or bacterial infections, but this has generally been regarded as a host's ...

Key to out-of-control immune response in lung injury found

... and auto-immunity through regulation of T- and B-cells. When sepsis was induced in mice with and without the Cblb gene, there was a marked ... of inflammatory cytokines, called NF-kB, is induced in lung tissue after sepsis by that receptor to a much greater extent from the Cblb-deficient mice ...

Sugar on bacteria surface serves as base for a web of resistance

... can foster creation of the biofilm. Some critically ill hospitalized patients also are susceptible to infection by Pseudomonas, which can lead to sepsis or bacteremia, common causes of death in very sick intensive-care patients. With Psl clearly identified as the foundation of the matrix, or the ...

Research could lead to new non-antibiotic drugs to counter hospital infections

... Once the host is weakened by an illness, surgical procedure or immunosuppressive drugs, however, P. aeruginosa can cause infection, inflammation, sepsis and death. Why P. aeruginosa can suddenly turn on its host has eluded researchersuntil now. Scientists have long known that after an operation ...

Lung airway cells activate vitamin D and increase immune response

... dampen inflammation," Hansdottir said. "Controlling inflammation through vitamin D is good because too much inflammation can cause problems such as sepsis and seems to contribute to autoimmune disease." Hansdottir noted that vitamin D insufficiencies and deficiencies (which are more severe) are ...

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Sepsis in Biological Technology

Spectral announces publication demonstrating Toraymyxin(TM) significantly reduces mortality from sepsis in prospective controlled trial

... reduced 28-day mortality in patients with severe sepsis and septic shock. The article entitled "Early Use ... the EUPHAS trial is an unprecedented result for sepsis therapies and indicates that this product has the ... 100,000 patients that develop severe sepsis or septic shock in the U.S. each year," said Dr. ...

Spectral announces first quarter 2009 results

... in Europe and Japan, for the treatment of severe sepsis and has demonstrated a significant reduction in the mortality of patients with severe sepsis compared to standard of care. We believe that, ... growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies being ...

Spectral announces presentations at the 29TH International Symposium on Intensive Care and Emergency Medicine focusing on the role of endotoxin

... such as defining the role that endotoxin plays in sepsis and organ dysfunction; using Spectral's Endotoxin ... and treating endotoxemia in patients with severe sepsis and septic shock. "The prominence given to ... 100,000 patients that develop severe sepsis or septic shock each year. Additional information ...

Spectral announces 2008 financial results

... to delivering an effective treatment for severe sepsis for the U.S. market," said Dr. Paul Walker, ... a therapeutic for the treatment of sepsis that removes endotoxin from the bloodstream, and ... in the mortality of patients with severe sepsis compared to standard of care in European trials. ...

Spectral signs exclusive license agreement to bring sepsis therapeutic to the U.S. market

... a therapeutic device for the treatment of sepsis that removes endotoxin from the bloodstream. ... to delivering an effective treatment for severe sepsis in the United States. Toraymyxin(TM) has been ... in Europe and Japan, for the treatment of severe sepsis caused by endotoxemia," said Dr. Paul Walker, ...

Spectral announces third quarter 2008 results

... a therapeutic for the treatment of sepsis that removes endotoxin from the bloodstream and ... elevated endotoxin levels that develop severe sepsis or septic shock in the U.S. each year." Dr. ... growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies ...

Cepheid Receives FDA Clearance for First On-Demand Diagnostic Test for Life-Threatening MRSA and Staphylococcus aureus From Patient Positive Blood Cultures

... with MRSA or SA, which are frequent causes of sepsis in hospitalized patients. This may enable ... New England Journal of Medicine, the incidence of sepsis is growing at 8.7 percent annually in the U.S., ... than one million by 2010, while cases of severe sepsis account for up to 11 percent of ICU admissions. ...

Spectral to bring anti-sepsis therapy to the U.S. market

... a combined product for the treatment of severe sepsis that will include Toraymyxin(TM) and Spectral's ... and has been used to treat more than 50,000 sepsis patients safely and effectively. Spectral's EAA ... 100,000 patients that develop severe sepsis or septic shock in the U.S. each year." "The ...

U.S. Clinicians Indicate a Strong Need for New Tools to Combat Sepsis

... to quickly diagnose and combat severe bacterial sepsis in U.S. hospitals. Sepsis, a usually fatal ... to assess the risk of progression to severe sepsis and septic shock. PCT tests have been used ... to the current methods of diagnosis and care for sepsis and suspected sepsis. Because symptoms ...

Spectral announces continuing support for the combination of EAA(TM) and anti-endotoxin therapeutics

... be presented at International Shock Congress by sepsis thought leaders - ... (EAA(TM)) as a diagnostic tool for anti-endotoxin sepsis treatment". Dr. Eugen Faist of the University of ... and immune profiles of patients with acute sepsis due to major peritonitis". Information on the ...
Sepsis in Biological Definition

Bacterium

... Some bacteria act as pathogens and cause tetanus , typhoid fever , pneumonia , syphilis , cholera , foodborne illness and tuberculosis . sepsis , a systemic infectious syndrome characterized by shock and massive vasodilation, or localized infection, can be caused by bacteria such as ...

Blood

... blood contact. Owing to blood-borne infections, bloodstained objects are treated as a biohazard . Infection of the blood is bacteremia or sepsis . Malaria and trypanosomiasis are blood-borne parasitic infections. Treatment Blood transfusion is the most direct therapeutic use of ...

Bacterium

... Some bacteria act as pathogens and cause tetanus , typhoid fever , pneumonia , syphilis , cholera , foodborne illness and tuberculosis . sepsis , a systemic infectious syndrome characterized by shock and massive vasodilation, or localized infection, can be caused by bacteria such as ...

Redox

... is dependent on these ratios. An abnormal redox state can develop in a variety of deleterious situations, such as hypoxia , shock , and sepsis . See also Bioremediation Calvin cycle Citric acid cycle Electrochemistry Galvanic cell External link ...

Redox

... is dependent on these ratios. An abnormal redox state can develop in a variety of deleterious situations, such as hypoxia , shock , and sepsis . See also Bioremediation Calvin cycle Citric acid cycle Electrochemistry Galvanic cell External link ...
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