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Selective in Medical News

InteKrin Therapeutics Announces INT131 Phase 2a Results at the 2009 American Diabetes Association Annual Meeting

... "These data are supportive of INT131 acting as a selective modulator of PPARgamma in T2DM patients," ... into the clinic is an exciting validation of the selective PPAR modulator design of the molecule," added Dr ... a next-generation, non-TZD insulin sensitizer and selective modulator of PPARgamma (SPPARM). INT131 belongs ...

Shire's INTUNIV (Guanfacine) extended release in children with ADHD and oppositional symptoms

... on INTUNIV (guanfacine) extended release, a selective alpha-2A-agonist, at a major psychiatric meeting. ... Once available, INTUNIV will be the first selective alpha-2A receptor agonist approved for the ... understood, preclinical research suggests this selective alpha-2A agonist strengthens working memory and ...

Presented Data Confirm That RAPAFLO(TM) (silodosin) Provides Rapid, Highly Effective, Symptom Relief for Benign Prostatic Hyperplasia (BPH) Patients

... - Uniquely selective Agent Offers Significant Improvement - ... treatment. RAPAFLO (TM) is a new, uniquely selective alpha blocker for the treatment of the signs and ... RAPAFLO (TM) is an effective, uniquely selective alpha-1 adrenergic receptor antagonist. RAPAFLO ...

Stunning finding: Compounds protect against cerebral palsy

... pharmaceutical companies so far have not: highly selective compounds that inhibit the enzyme found in brain ... until they had a few compounds that were very selective and very potent for the brain enzyme. ... enzyme. Silverman sent him several potent and selective compounds, and Poulos produced crystal structures ...

California Woman Receives Most Advanced, Non-Invasive Upper Extremity Prosthetic Solution: Bionic i-LIMB Hand and Innovative Interface System Increase Amputee's Functionality and Confidence

... - Touch Bionic's i-LIMB Hand and biodesigns' selective compression-stabilization interface. Amputee now ... bionic hand, coupled with the innovative selective compression-stabilization interface system ... by a specially trained artist. Alley's selective compression-stabilization system is a ...

EntreMed Teams with JSB-Partners to Expedite Partnering of its Aurora Kinase Program

... ) ENMD-2076 is a novel, orally-active, selective kinase inhibitor with potent activity against ... opportunities for our unique, orally-active, selective kinase inhibitor, ENMD-2076. The relationship ... a novel antimitotic agent, and ENMD-2076, a selective kinase inhibitor, are in Phase 1 studies in ...

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Selective in Medical Technology

Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms

... is characterized by Wyeth as a TSEC (tissue selective estrogen complex) as it combines a selective estrogen receptor modulator (SERM) with ... Protection in Menopausal Therapy with a Tissue selective Estrogen Complex (TSEC) Containing ...

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

... we show that plant-derived ERb compounds are as selective as synthetic compounds, but regulate different ... the analyses of three distinct classes of ERb selective drugs. The study determines the relative ER ... of gene expression of the three classes of ERb selective compounds compared to the natural hormone ...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

... published today in Nature Medicine, Proteolix's selective immunoproteasome inhibitor PR-957 was shown to ... July 2009 print edition in an article titled: A selective Inhibitor of the Immunoproteasome Subunit LMP7 ... Chief Scientific Officer at Proteolix. "This selective inhibition of the immunoproteasome results in an ...

Proteolix Presents Phase 1b/2 Clinical Data for Carfilzomib in Advanced Solid Tumor Patients at the 2009 ASCO Annual Meeting

... demonstrated promising activity as a highly selective and potent inhibitor of the proteasome for ... A Phase Ib/II study of carfilzomib (CFZ), a selective proteasome inhibitor, in patients with selected ... a selective, oral proteasome inhibitor and a selective immunoproteasome inhibitor. For additional ...

Shire Announces Study Results of the Effects of INTUNIV(TM) (Guanfacine) Extended Release on Secondary Measures in Children with ADHD and Oppositional Symptoms

... on INTUNIV (guanfacine) extended release, a selective alpha-2A-agonist, at a major psychiatric meeting. ... Once available, INTUNIV will be the first selective alpha-2A receptor agonist approved for the ... understood, preclinical research suggests this selective alpha-2A agonist strengthens working memory and ...

RAPAFLO(TM) (silodosin) Provides Rapid and Sustained Benign Prostatic Hyperplasia (BPH) Symptom Relief in as Little as Three Days

... -- RAPAFLO (TM) (silodosin), a new, uniquely selective alpha blocker for the treatment of the signs and ... reduced semen), an expected treatment effect of selective alpha blockers, which occurred in 28 percent of ... RAPAFLO(TM) is an effective, uniquely selective alpha-1 adrenergic receptor antagonist. ...

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Selective in Medical Products

5.2F Supertorque Plus

Description:... Femoral selective diagnostic catheter.The material used is polyurethane (DUCOR). All selective shapes have thrulumen design. Guidewire campatibility is 0.038". Packaging ...
Company:Cordis Corporation

6F Infiniti

Description:... Femoral selective diagnostic catheter.The material used is polyurethane (DUCOR). All selective shapes have thrulumen design. Guidewire campatibility is 0.038". Packaging ...
Company:Cordis Corporation

4F Infiniti

Description:... Femoral selective diagnostic catheter. The material used is nylon (VESTANTM). All selective shapes have thrulumen design. Guidewire campatibility is 0.038". Packaging ...
Company:Cordis Corporation

5F Infiniti

Description:... Femoral selective diagnostic catheter. The material used is nylon (VESTANTM). All selective shapes have thrulumen design. Guidewire campatibility is 0.038". Packaging ...
Company:Cordis Corporation

CUSA Excel Ultrasonic Surgical Aspirator

Description:... CUSA EXcel system is the recognized world leader, providing rapid, selective tissue fragmentation with superior tactile feedback and exceptional ... to provide unsurpassed performance in procedures requiring precise, selective tissue ....
Company:Valleylab

VASER Ultrasound Lipoplasty System

Description:... a major advance in the application of ultrasonic technology to cosmetic procedures. Combined with precision fluid management, controlled and selective tissue emulsification, a solid grooved probe design and patented cannulae, only the VASER System has been designed to minimize trauma to the tissue ...
Company:Sound Surgical Technologies LLC

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Selective in Medical Definition

Medical Scientist Training Program

... Medical Scientist Training Programs are highly selective combined M.D. and Ph.D. graduate degree programs offered by a number of U.S. medical schools with grant support from the National ...

Proteopathy

... pl .; proteopathic adj .). Proteopathy is the abnormal accumulation and toxicity of proteins in certain disease states. [1] Also, selective hyperproteolytic diseases have been referred to this category, e.g. critical illness myopathies or tumor cachexia. [2] The proteopathies comprise ...

Thymocyte

... prerequisite for thymopoiesis. Immunol Rev 209:47, 2006. full text ^ Schwarz BA, Sambandam A, Maillard I, Harman BC, Love PE, Bhandoola A. selective thymus settling regulated by cytokine and chemokine receptors. J Immunol. 2007 Feb 15;178(4):2008-17. ...
Selective in Medical Dictionary

Abortion

... time in their reproductive lives. Abortion , selective Definition selective abortion , also known as selective reduction, refers to choosing to abort a fetus , ...

Obsessive

... , a type of drugs used to treat depression , selective serotonin reuptake inhibitors (SSRIs; such as ... of choice. The majority of people who exhibit selective mutism appear to have some type of acute ... \ ',CAPTION, ... Zoloft (sertraline HCl) A selective serotonin reuptake inhibitor (SSRI) for the ...

Serotonin

... test that measures the amount of serotonin . selective serotonin reuptake inhibitors (SSRIs) balance ... s, digestive tract, and pineal gland . selective serotonin reuptake inhibitors maintain levels ... They do not alter levels of norepinephrine . selective Serotonin Reuptake Inhibitors are useful in the ...

Breasts

... characteristics, such as the breasts , body shape, and body hair . selective estrogen receptor modulator (SERM) New class of drug with selective ability to affect the skeletal and cardiovascular systems similar to ...

Estrogen

... States include the following: Estrogen s Ethinyl estradiol ... selective estrogen receptor modulator (SERM) New class of drug with selective ability to affect the skeletal and cardiovascular systems similar to ...

Obsessive-compulsive disorder

... and panic type anxiety , a type of drugs used to treat depression , selective serotonin reuptake inhibitors (SSRIs; such as Prozac and Paxil), are the treatment of choice. Zoloft (sertraline HCl) A selective serotonin reuptake inhibitor (SSRI) for the treatment of panic ...

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Selective in Biological News

What is wild? Odor attraction among different wildtype Drosophila

... flies ( Drosophila melanogaster ) show a highly selective behavior towards odor stimuli. A series of ... these varieties turned out to be particularly selective and displayed slower and less strong responses to ... Canton-S and both Oregon-R-C and R-S, were not as selective in the experiments as the newly collected Swedish ...

Gene's 'selective signature' aids detection of natural selection in microbial evolution

... evolution. The new method determines the selective signature of a gene, that is, the pattern of fast ... of Civil and Environmental Engineering. The selective signature method also allows us to focus on a single species and better understand the selective pressures on it. Our hope is that other ...

2008 Pew Fellowship in Marine Conservation awarded to Dr. Marie-Joëlle Rochet from IFREMER

... from France, will compare the impact of selective fishing, in which commercial fishermen ... food webs and degrading the marine ecosystem. selective fishing methods that harvest only the desired ... research and policies that support more selective fishing methods, or, advocating for non-selective ...

After more than 100 years apart, webworms devastate New Zealand parsnips

... less susceptible to that environmental factor, or selective agent, enjoy a reproductive advantage, ... the newly arrived parsnip webworms are a major selective agent, Zangerl said, wiping out a majority of the ... the insect and we have shown that the insect is a selective agent. Berenbaum and Zangerl have spent ...

University of Houston diesel testing center teams with state transportation agency to cut emissions

... researchers will supervise the installation of Nett Technologies' BlueMAX selective catalytic reduction system, which is classified by the EPA as an emerging ... engines, diesel particulate filters and fume diluters. The Nett BlueMAX selective catalytic reduction (SCR) system is designed to control nitrogen oxide ...

Geography and history shape genetic differences in humans

... If the individual populations' environments were exerting strong selective pressure, such differences should have been apparent. Selection may ... people will start figuring out the phenotypes that are associated with selective signals," says lead author Graham Coop. "That will be very important, ...

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Selective in Biological Technology

Peregrine Pharmaceuticals Licenses Anti-VEGF Antibodies to Affitech

... and commercialize products under Peregrine's selective anti-VEGF intellectual property portfolio, ... an excellent opportunity for both companies. The selective anti-VEGF antibodies we have been jointly ... successfully identified fully human, potent and selective anti-VEGF antibodies as part of a previous ...

Intellikine Completes $51 Million Financing

... classes of proprietary compounds that are potent, selective and druglike inhibitors of PI3K isoforms. The company's most advanced compound, INK128, a selective TORC1/2 inhibitor, has demonstrated efficacy in ... most advanced compound, INK128, a potent and selective TORC1/2 inhibitor with exceptional drug-like ...

Retrospective Analysis of Phase 3 Data Suggest Wyeth's Investigational Compound Bazedoxifene/Conjugated Estrogens Comparable to Placebo on Incidence of Abnormal Mammograms

... Wyeth describes this compound as a tissue selective estrogen complex (TSEC). In a retrospective ... over two years. BZA is an investigational selective estrogen receptor modulator (SERM) under ... About TSEC Wyeth describes the pairing of a selective estrogen receptor modulator (SERM) and one or ...

Abbott Scientists Present a New Approach for Treating Attention-Deficit Hyperactivity Disorder

... present new Phase II data showing that ABT-089, a selective neuronal nicotinic receptor (NNR) agonist, is ... alpha 4 beta 2 NNR Agonist Program ABT-089 is a selective NNR agonist, which targets the alpha 4 beta 2 NNR ... 7 NNR Agonist Program ABT-107 is a potent and selective NNR agonist, which targets the alpha 7 NNR ...

Bionovo Identifies and Describes ER-beta Selective Compounds for the Treatment of Vaginal Dryness

... elucidation of active estrogen receptor beta selective compounds from VG101, Bionovo's drug candidate ... and synthesized three analogues displaying selective estrogen receptor beta activity, which is the ... women. VG101 is a novel estrogen receptor beta selective agonist and unlike currently available ...

VaxGen Issues Rebuttal to MedCap Letter

... exacerbated by MedCap's inaccurate and highly selective use of third party references. MedCap draws on ... MedCap continues this pattern of selective quotation in a further release dated March 20, ... not referenced by MedCap. MedCap's selective use of these third party sources is ...

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Selective in Biological Products

Rabbit Protein Phosphatase 1 (PP1) from Upstate

Description:... PP1, purified Formulation: 0.15M NaCl, 20mM MOPS, pH 7.5, 60mM 2-mercaptoethanol, 0.1mM MnCl2, 1mM MgCl2, 1mM EGTA, 10 Properites: For selective in vitro dephosphorylation of proteins Purification: DEAE chromatography, divalent cation activation plus trypsin digestion, and gel filtration ...
Company:Upstate

GIBCO Geneticin Selective Antibiotic liquid from Invitrogen

Description:... Geneticin selective Antibiotic ...
Company:Invitrogen

One•STrEP™ Protein Interaction Kit from Novagen

Description:... protein complexes. Unlike other systems that require tedious optimization or multiple purification steps, this system takes advantage of the highly selective StrepTactin Superflow Column for fast protein purification under physiological conditions with low background. With the OneSTrEP Protein Interaction ...
Company:Novagen

Anisomycin from Sigma-Aldrich

Description:... cells, Jurkat cells, ventricular myocytes, and colon adenocarcinoma cells. Initiates intracellular signals and immediate early gene induction. selective signaling agonist. Potent Jun-NH2terminal kinase (JNK) agonist. Activates mitogen-activated protein (MAP) kinases (JNK/SAPK and p38/RK). ...
Company:Sigma-Aldrich

SureLINK Bioconjugation Kit from KPL

Description:... in the SureLINK Bioconjugation Kit is superior to conventional methods of bioconjugation such as maleimide/thiol and avidin/biotin. Using a highly selective interaction of hydrazine and carbonyl groups, the coupling reaction results in a hydrazone bond that is extremely stable. Additionally, no reducing ...
Company:KPL

S1 Nuclease from Promega

Description:... except with extremely high concentrations of enzyme (1). The enzyme is used to remove single-stranded termini from double-stranded DNA (2), for selective cleavage of single-stranded DNA and for mapping RNA transcripts ....
Company:Promega

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Selective in Biological Definition

Evolution

... of any species, in such a way as to result in new selective forces. Genetic drift Genetic drift ... in allele frequency that cannot be ascribed to selective pressures, but are due instead to events that are ... altering the allele frequency outside of "normal" selective pressures. Many aspects of genetic drift depend ...

Molecular evolution

... in gene frequency that cannot be ascribed to selective pressures, but are due instead to events that are ... , meaning mutations that do not convey a selective advantage or disadvantage to the individual that ... locus. Beyond this number of alleles, the selective advantage of presence of those alleles in ...

Pigment

... in plant or animal cells which is the result of selective absorption. Some biological material has so-called structural color, which is the result of selective reflection or iridescence , usually done with ... . Because pigment color is the result of selective absorption, there is no such thing as white ...

Apoptosis

... - specifically on chick neural tube development - has suggested how selective cell proliferation, combined with selective apoptosis, sculpts developing tissues in vertebrates. During vertebrate ...

Eugenics

... of eugenics 8.2 Pro-eugenics websites Galton's theory selective breeding was suggested as early as the time of Plato , who believed that ... based on the Mendelian laws. Eugenics developed to refer to human selective reproduction with the intent to create children with desirable traits, ...

Selective serotonin reuptake inhibitor

... selective serotonin reuptake inhibitors ( SSRIs ) are a class of antidepressants . ... of L-Tryptophan References Tamam, L. and Ozpoyraz, N. (2002). selective serotonin reuptake inhibitor discontinuation syndrome: a review. Advances ...

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Selective in Biological Dictionary

Nerve roots

... a green dot) were ... ... two main types of blocks - facet blocks and selective nerve root blocks. ... When one of the nerve roots is irritated, ... of one or more nerve roots result in ... Aetna considers diagnostic selective nerve root block (SNRB), also known as ... Spinal nerve roots , ...

Ubiquitin

... Mouse protein-coding gene Ubc. Represented by 2568 ESTs from 329 cDNA libraries. ... Ubiquitin , becomes conjugated to proteins, marking them for selective ... Ubiquitons and Zomes ( Ubiquitin and Proteasome) ... Ubiquitin -like Proteins and Derivatives. Ubiquitin and Ubiquitin -like Protein ...

TATA box

... of TATA box as a finance term. What does TATA box mean in finance? ... TATA box . Tax and loan account. tax anticipation bill. Tax ... selective Binding of the TATA Box -Binding Protein to the ... Binding Mechanisms of TATA Box -Binding Proteins: DNA Kinking is Stabilized by ... ...

Ribosome binding site

... dictionary,biology terminology,biology terms,biology abbreviations ... promoter and ribosome binding site codes in ... ... shows the selective binding site on the mRNA which is attached in the ribosome . ... After binding to the A site , the peptide bond between the methionine ... ...

Response element

... response capacity, will assist ... In most instances, the response elements will remain under State control. ... Direct repeats as selective response elements for the thyroid hormone, retinoic ... nucleotide, and the resulting retinoic acid response element is no longer a TRE. ... ...

Repetitive DNA

... in ... News archive for repetitive DNA . Anti-aging compound claims to reset the clock - 21 Aug 2007 ... Repetitive DNA , with different selective pressures from those acting on genes ... The repetitive DNA in the genome is also important for evolutionary, genetic, ... Repetitive , DNA ...

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(Date:7/11/2014)... News) -- In people with sex addiction, pornography affects ... seen in drug addicts as they consume drugs, a ... brain activity between patients who have compulsive sexual behavior ... addicts," study author Dr. Valerie Voon, of the University ... release. Voon,s research involved 19 men with sex ...
(Date:7/11/2014)... FRIDAY, July 11, 2014 (HealthDay News) -- U.S. health ... workers were exposed to live anthrax during a safety ... Disease Control and Prevention officials have announced a moratorium ... from high-level government labs. In a report issued ... take to make sure a similar incident doesn,t occur ...
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(Date:7/10/2014)... BLUE BELL, Pa. , July 2, 2014  Unisys ... The Netherlands , Unisys Nederland N.V., today announced that ... (DJI) to deliver, implement and manage a new Basic Provision ... . Unisys won the contract with a ... for identity management software. The term of the contract is ...
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