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Segregation in Medical News

Researchers solve first structure of a key to intact DNA inheritance

... and often lethal staph infection. "The plasmid segregation system we are working on, called pSK41, is found ... vancomycin," Schumacher says. "Because the segregation systems are essential for the retention of these ... and segregation, Schumacher says, because plasmid segregation is relatively simple: two proteins connect to one ...

Racial Disparities Widespread in Kidney Patient Outcomes

... Studies find mistrust, cultural barriers, segregation of care contribute to inequalities WEDNESDAY, June 4 ... lack of patient trust; cultural and communication barriers; residential segregation that groups minorities in communities with lower quality health care; ...

17 of America's Most Promising Scientists Selected as 2009 Pew Scholars in the Biomedical Sciences

... Jenn i fer G . D eL u c a, Ph. D . C olora d o St a te U n iv e r s i t y Mechanisms of mitotic chromosome segregation P a tr i ck J. Pad d iso n , Ph. D . Fred Hu t ch i nson Ca n cer R esea r ch Ce n ter Stem cell and ...

Grandson of Slaves Wins Experience of a Lifetime, Heads to Washington, D.C. to Attend Presidential Inauguration Events

... Returning to the South after serving duty, Bouey found that nothing had changed. There were no jobs for him, and segregation was still a major fact of life. In June of 1946, Bouey couldn't take it any longer, and moved to Chicago with $10 in ...

Med school discovery could lead to better cancer diagnosis, drugs

... His paper on the discovery has been published in the journal Proceedings of the National Academy of Sciences . "The correct timing of chromosome segregation during cell division is necessary to ensure normal, healthy growth," Wang said. "Now we have discovered a previously undetected layer of regulation ...

First Two Non African-American Graduates of Meharry Medical College to Receive Awards at 2008 Fall Convocation

... Distinguished Service Medal on his behalf. The admission of Drs. Lachman and Gorman to Meharry Medical College during the days of rigid racial segregation in America speaks volumes about the academic health center as a national treasure and of the strong moral and ethical character of the College's ...

NEWSWEEK: Media Lead Sheet/September 1, 2008 Issue (on newsstands Monday, August 25, 2008).

... for the United States. "Many have discoursed on what an Obama victory could mean for America. We would finally be able to see our legacy of slavery, segregation and racism in the rearview mirror. Our kids would grow up thinking of prejudice as a nonfactor in their lives," he writes. However, "if Obama loses, ...

Georgia to Offer More Community Living Alternatives for Individuals With Disabilities

... fullest extent possible. "In this voluntary compliance agreement with the Federal Government, Georgia promises a serious effort to end the illegal segregation of its citizens with disabilities and to provide appropriate community alternatives," said Sue Jamieson, the attorney with the Atlanta Legal Aid ...

Lack of CHFR gene expression sets stage for breast cancer

... unstable cells loaded with too many chromosomes, which can lead to cancer. "Our findings show that loss of CHFR disrupts normal chromosome segregation in breast cells during cell division and creates genomic instability, which can drive genetic mechanisms that accelerate the development of cancer," ...

Racial disparities in the outcomes of patients with chronic kidney disease abound

... in these and other disparities. Patient and societal factors include: lack of trust by patients, cultural and communication barriers, and residential segregation that clusters minorities in communities with lower quality health care resources. Factors at the level of health care systems include: lower rates of ...
Segregation in Medical Technology

Isogen Launches Major New Facility to Address Global Biopharma Demand

... process development, analytical laboratory services and pharmaceutical engineering consulting. Isogen's Advanced Sterile Filling offers full product segregation and isolator-based sterile processing. The facility meets global regulatory standards and operates according to cGMP. Isogen's industry subject ...

Nemours Center for Childhood Cancer Research Team at the Alfred I. duPont Hospital for Children Identifies the Function of a Biomarker Present in Prostate Cancer Cells: New Insight into Therapeutic Benefit for Patients with Advanced Prostate Cancer

... are equally separated during cell division. Anaphase-promoting complex (APC) is one such checkpoint regulatory protein involved in the proper segregation of chromosomes during cell division. This complex monitors the timing of cell division and provides sufficient time for cells to segregate ...

EntreMed Commences Continuous Dosing Clinical Trial For MKC-1

... in multiple Phase 1 and 2 clinical trials. MKC-1 has been shown to induce apoptosis, inhibit mitotic spindle formation, and prevent chromosome segregation in the M-phase (mitosis) of the cell cycle. Furthermore, MKC-1 inhibits the PI3K-Akt-mTOR signaling pathways, which may occur through inhibition of ...

EntreMed Commences Phase 2 Study With MKC-1 in Ovarian/Endometrial Cancers

... multiple preclinical models, including paclitaxel-resistant models. MKC-1 has been shown to inhibit mitotic spindle formation, prevent chromosome segregation in the M-phase (mitosis) of the cell cycle, and induce apoptosis. Furthermore, MKC-1 inhibits the Akt-mTOR signaling pathways, which may occur ...

EntreMed Shows Increased Survival With MKC-1 in Preclinical Renal Cell Cancer Model

... in multiple preclinical models, including paclitaxel-resistant models. MKC-1 has been shown to inhibit mitotic spindle formation, prevent chromosome segregation in the M-phase (mitosis) of the cell cycle, and induce apoptosis. Furthermore, MKC-1 inhibits the Akt-mTOR signaling pathways, which may occur ...

EntreMed Presents Data for Phase 2 Study of MKC-1 in Metastatic Breast Cancer

... trafficking that has been shown to be involved in cell division. MKC- 1 has been shown to inhibit mitotic spindle formation, prevent chromosome segregation in the M-phase of the cell cycle, and induce apoptosis in multiple cell lines, consistent with a mechanism in which MKC-1 blocks the nuclear uptake ...

EntreMed Presents Preclinical Data for MKC-1 in Hematological Cancers

... in multiple preclinical models, including paclitaxel-resistant models. MKC-1 has been shown to inhibit mitotic spindle formation, prevent chromosome segregation in the M-phase (mitosis) of the cell cycle, and induce apoptosis. These effects are consistent with mechanisms resulting from MKC-1 binding to ...
Segregation in Medical Dictionary

Chromosome

... s (XX for a female and XY for a male). The size, shape, and structure are normal for each chromosome . Abnormal: ... Regulation of Chromosome segregation Research Interest: An important question in our understanding of cancer , a genetic disease , is how chromosome s change in cancer cells. ...

Genetics

... ... Trait: In genetics , a trait refers to any genetic ally determined characteristic. In technical terms, a genetic trait is amenable to segregation analysis rather than quantitative analysis. DELETION: In genetics , any spontaneous elimination of a section of genetic material (ie, from a ...
Segregation in Biological News

Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation

... a key cellular structure in powering and controlling chromosome segregation and accurate cell division, has just earned him a paper in Nature Cell ... provides new insights into the scaffold of proteins that ensures accurate segregation of chromosomes during cell division - a fundamental step to ensure that ...

Separating the good from the bad

... left-handed brethren, impelling the microbes in opposite directions. This finding and the possibility of quickly and cheaply implementing the segregation of two-handed objects in the laboratory could have a big impact on industries like the pharmaceutical industry, for which the separation of ...

Damon Runyon Cancer Research Foundation awards prestigious fellowships to 13 top young investigators

... C. Harrison, PhD, at Harvard Medical School, Boston, Massachusetts, is studying the structure of kinetochores, protein complexes that mediate the segregation of chromosomes during cell division. Discrepancies in the distribution of chromosomes in divided cells occur in many cancers and diseases such as ...

February 2009 Geology and GSA Today media highlights

... have caused them to be regarded differently in geological research than older, generally more lithified strata. This has been exacerbated by the segregation of the Quaternary research community into different schools of geology and geography, producing redundant nomenclature, multiple classification ...

Dartmouth researchers find new protein function

... HANOVER, NH A group of Dartmouth researchers has found a new function for one of the proteins involved with chromosome segregation during cell division. Their finding adds to the growing knowledge about the fundamental workings of cells, and contributes to understanding how cell ...

Keeping chromosomes from cuddling up

... Sweeney and Peter J. Knepler, both at the UA, and Bosco published their paper, "Condensin II Resolves Chromosomal Associations to Enable Anaphase I segregation in Drosophila Male Meiosis," in the October 2008 issue of PLoS Genetics. Sweeney and Knepler were UA undergraduates when they conducted the research. ...

December 2008 Geology and GSA Today media highlights

... trace element data, and gold occurrence, the data demonstrate that metamorphism has gradually homogenized the early sulfur, accompanied by the segregation of quartz and the release of gold from the lattice of early pyrite and its re-precipitation as inclusions in later pyrite. The sulfur isotopic ...

Scripps research team defines new painkilling chemical pathway

... induced other effects associated with the cannabinoid receptors, namely hypothermia and decreased movement. "This really does suggest a sort of segregation of labor, if you will," says Cravatt of the differential effects of elevating AEA versus 2-AG as part of the overall function of the cannabinoid ...

Cancer signatures uncovered

... group of cancers that present as a transition phenotype between these two extremes and displays both characteristics. According to Kohane, "This segregation of tumors into three groups with distinct expression patterns is surprising. Clearly, the developmental trajectory provides a meaningful background ...

Scientists find color vision system independent of motion detection

... humans. In human vision, it had been widely believed that color and motion were processed by parallel pathways. More recently, however, the complete segregation of motion detection and color vision came into question. To explore this matter, the NYU and University of Wrzburg researchers examined the fruit ...

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Segregation in Biological Technology

Telik Reports Preclinical Results at AACR Annual Meeting

... Active Aurora Kinase/ VEGFR Inhibitors; Abstract # 1764 Aurora kinases are Ser/Thr kinases that play an important role in chromosome alignment, segregation and cytokinesis during mitosis. Over-expression of Aurora kinases has been demonstrated in both solid tumors and leukemia and is considered to be ...

EntreMed's MKC-1 Meets Primary Efficacy Endpoint in Non-Small Cell Lung Cancer Clinical Trial

... multiple preclinical models, including paclitaxel-resistant models. MKC-1 has been shown to inhibit mitotic spindle formation, prevent chromosome segregation in the M-phase (mitosis) of the cell cycle, and induce apoptosis. Furthermore, MKC-1 inhibits the Akt-mTOR signaling pathways, which may occur ...

CBDM.T, The Market and Business Intelligence Company Reviews The Biomanufacturing Market

... 10 to 15%. Pharmaceutical biomanufacturing could account for more than 20% of the global contract manufacturing market in 2012. If we analyze the segregation of production capacity between CMOs (Contract Manufacturing Organisations) and product development companies, the "build versus buy" ...

Auditors paying more attention to IT woes

... involved access to programs and data (includes segregation of duties). 31 percent were related to ... faithfully executing these procedures. Inadequate segregation of duties, both within IT and the business, was ... these findings was wide: change control, backup, segregation of duties, etc. Vendors and SAS-70 Out of ...

Managing SOX in the age of SOA

... to financial applications that have been exposed as Web services. segregation of roles Segregation of roles is a core technique of internal controls ... authorization, it may be impossible to establish clear role segregation in an SOA. If the "user" of a Web service-based financial application is ...

Companies still neglect network security

... be thinking about it in terms of an ice storm in Wisconsin. Is it going to happen? Yeah." Running the gauntlet Practices such as establishing segregation of duties, identifying what employees can have access to sensitive information, and controlling what can be copied onto a USB flash drive should be ...

Technology helps but the best way to reduce Sarbox cost is with people

... Wrong skill sets for position. Poor training. Overwhelming workloads. Excessive staff turnover. Poor accountability. Weak segregation of duties. Poor supervision. Floored by 404 These challenges are nothing new. However, they are coming to the forefront largely due to ...

Testing Compressed Air Lines for Microbiological Contamination

... design the facility whereby the air compressor is segregated from the area where the product is assembled for logical hygienic reasons. However, this segregation may lead to a false sense of security because it is possible that the environmental air source that feeds into the compressor may contain biological ...

SNPs Powerful Tools for Association Studies

... and the putative disease allele. Under such circumstances, only a higher density map, such as a SNP map, will be able to follow the recombination and segregation of alleles (also seeChoosing SNPs for an Association Study below). This density is defined by the observed average size of co-inheritance blocks, ...

Analysis of in vitro micronucleus assays using the IN Cell Analyzer 3000 Micronuclei Formation Analysis Module

... of genotoxic compounds and analysis of micronuclei formation resulting from DNA strand breakage (clastogens) or interference with chromosome segregation (aneugens) is an important component of toxicology screening of new drug candidates. Manual scoring of micronucleus assays is time consuming and ...

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Segregation in Biological Definition

Eugenics

... eugenics). "Negative" eugenic policies in the past have ranged from segregation to sterilization to even genocide . "Positive" eugenic policies have ... restriction and sterilization as primary methods, Goddard favored segregation in his The Kallikak Family , Grant favored all of the above and more -- ...

Mendelian inheritance

... had the impact it made on the world of genetics. Mendel's law of segregation Mendel's law of segregation essentially has three parts. Alternative versions of genes account ...

Mitosis

... in mitosis In biology , mitosis is the process of chromosome segregation and nuclear division that follows replication of the genetic material in ... to kinetochores, they begin to line up in the middle of the cell. Proper segregation requires that every kinetochore be attached to a microtubule before ...

Mitosis

... in mitosis In biology , mitosis is the process of chromosome segregation and nuclear division that follows replication of the genetic material in ... to kinetochores, they begin to line up in the middle of the cell. Proper segregation requires that every kinetochore be attached to a microtubule before ...
Segregation in Biological Dictionary

Segregation

... Racial segregation is the separation of different racial groups in ... to the movies, or in the rental ... Racial segregation in the United States, as a general term, included the racial segregation of facilities, services, and opportunities such ...

Segregating

... from Ed Coe (email) (please state ... segregation n. The act or process of segregating or the ... the mentally ill ... abuse, neglect and unneeded segregation . ... Dynamic instability and bipolar stabilization drive plasmid segregation . ... tion of a DNA- segregating system from ...

Post-meiotic segregation

... Anti- Post Meiotic segregation Increased 2. Species Reactivity. Key Applications. Host ... Anti- Post Meiotic segregation Increased 2 - Data Sheet ... Anti- Post Meiotic segregation Increased 2 - Data Sheet. Catalogue Number: ...

Mendelian inheritance

... . ... Mendelian inheritance describes three laws or basic principals of ... Mendelian Inheritance from Answers.com. Mendels Law of segregation Biology from About.com ... A brief, readable, introduction to the basic principles of genetics and heredity. Reviews older theories of ...

Kinetochore

...... kinetochore A disc of proteins located on the centromere, ... 7. Kinetochore assembly. 8. Assembly of the mitotic spindle. 9. Chromosome segregation ... A number of other kinetochore proteins have been identified whose depletion ... Cell cycle articles relating to ' kinetochore ' ... The ...

Homozygous

... HancockHorses.com, portal website for Hancock bred horses. ... This is consistent with the homozygous lethal roan gene theory. ... law of segregation principle of heredity seed shape nbsp nbsp nbsp nbsp nbsp independent assortment: Definition of homozygous . Definition of the word ...

Heteroduplex

... a unique ... Thus a heteroduplex joint initiated at one end of the duplex DNA grows by ... arrangement of heteroduplex DNA in the postmeiotic segregation products reveals ... to generate noncrossover products in which heteroduplex is unrepaired. ... Assembly of the MutL·MutS· heteroduplex ...

Hereditary Unit

...... 1. There are hereditary traits controlled by units (the term gene' was ... Although the individual hereditary units follow the laws of segregation and ... The presence of hereditary units in the cytoplasm was first hypothesized in 1902 ... Encyclopedia article about Genes. Information ...

Genetic linkage

... to Genetic Linkage ? 9 Tooo much redundant ... Genetic Linkage Analysis Software. This is a list of genetic linkage ... for segregation analysis, linkage calculations, genetic counseling, and related ... Genetic Linkage Evidence. Why Study Ashkenazim? Educational ....

Diakinesis

... past diakinesis and exhibited several different alterations. ... The events of diplotene– diakinesis prepare chromosomes for their segregation ... Diakinesis bivalents must be condensed, resolved, and reorganized into a ... diakinesis - Hutchinson encyclopedia article about ...

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Other Contents
(Date:4/14/2014)... orphaned by HIV/AIDS in South Africa may provide insight ... behavior issues in other areas of the world, which ... that could lead to successful interventions. , A ... United Nations mentions that due to the HIV/AIDS pandemic, ... African, children are at an increased risk for mental ...
(Date:4/14/2014)... A new study shows that moderate to severe ... risk of stroke, cancer and death. , Results of ... to severe obstructive sleep apnea were four times more ... times more likely to have a stroke (HR = ... (HR = 3.4), and 2.5 times more likely to ...
(Date:4/14/2014)... Dallas study involving serious youth offenders, the answer to one ... seven years: "How long do you think you,ll live?", According ... offending over time., Author Dr. Alex Piquero said the study ... of them offend at very high rates and commit more ... much later in life offend much less., "In a lot ...
(Date:4/14/2014)... with symptoms increasing dramatically during some of the most important ... has found. , Depressive symptoms increased on average by 68 ... young men, who were around 25 years old when they ... their children. The results of the study were published April ... is the first to identify when young fathers are at ...
(Date:4/14/2014)... Lower weight babies and babies who aren,t breastfed ... risk of developing chronic inflammation and related health ... study. , "There were good reasons to hypothesize ... inflammation in adulthood," says Thomas McDade (Northwestern University), ... in the Child & Brain Development program. "It ...
Breaking Medicine News(10 mins):Health News:Researchers identify children with emotional behavior difficulties 2Health News:Researchers identify children with emotional behavior difficulties 3Health News:Study links severe sleep apnea to increased risk of stroke, cancer and death 2Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Young dads at high risk of depression, too 2Health News:Low birth weight, less breastfeeding create later health risks 2
(Date:4/16/2014)... known as Kennedy,s disease, spinal and bulbar muscular atrophy ... slowly progressive muscle weakness and atrophy. Researchers have long ... motor neurons the cells in the spinal cord ... a new study published in the April 16, 2014 ... scientists at the University of California, San Diego School ...
(Date:4/16/2014)... we do all of our movements, thoughts and ... one another, and recent studies have suggested that some ... Brain cells known as astrocytes may be listening in ... But a new mouse study suggests that astrocytes might ... specifically, when the neurons get really excited about something. ...
(Date:4/16/2014)... Panagiotis Papatheodorou from the Institute of Experimental and Clinical ... discovered the receptor responsible for smuggling the toxin of ... The TpeL toxin, which is formed by C. ... food poisoning. It is very similar to the toxins ... Clostridium . The toxins bind to surface molecules and ...
Breaking Biology News(10 mins):Mutant protein in muscle linked to neuromuscular disorder 2Eavesdropping on brain cell chatter 2Eavesdropping on brain cell chatter 3Gate for bacterial toxins found 2
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