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Scrapie in Medical News

Orchid Cellmark Reports Fourth Quarter and Full Year 2008 Financial Results

... offset by lower volumes of animal DNA testing for scrapie susceptibility. U.S.-based revenues for the 2008 ... ago was due to lower volumes in the company's scrapie susceptibility testing, forensics and immigration ... was adversely impacted by decreased volumes in scrapie susceptibility testing and lower margin revenues ...

Scripps Florida scientists devise accelerated method to determine infectious prion strains

... as well as humans. Different strains of the infectious agent, called a prion, cause mad cow disease, chronic wasting disease, and different forms of scrapie and human Creutzfeldt-Jacob disease. Mad cow disease has had devastating consequences for bovine livestock populations, particularly in Europe, ...

Orchid Cellmark Reports Improved First Quarter 2009 Financial Results

... by decreased revenues for PACE (Police and Criminal Evidence Act) and paternity testing, and the expected lower volumes of animal DNA testing for scrapie susceptibility. In dollars, total U.K.-based revenues for the first quarter of 2009 increased by approximately 1% over the first quarter of 2008. ...

Orchid Cellmark Reports Third Quarter 2008 Financial Results

... and state DNA databases. The decrease in U.K.-based revenues in the quarter compared to a year ago was due to lower volumes of animal DNA testing for scrapie susceptibility and slightly reduced forensics revenues due to adverse exchange rates. Excluding cost of service revenue, operating expenses for the ...

Orchid Cellmark Reports Second Quarter 2008 Financial Results

... in U.K.-based revenues in the second quarter of 2008, compared to the comparable period in 2007, was due to lower volumes of animal DNA testing for scrapie susceptibility and immigration identity testing, as well as reduced forensic revenue. The decrease was partially offset by increased revenues in the ...

Orchid Cellmark Reports First Quarter 2008 Financial Results

... the first quarter of 2008 compared to the comparable period in 2007 was due to lower volumes of immigration identity testing, animal DNA testing for scrapie susceptibility and reduced forensic revenue. Total operating expenses, excluding cost of service revenue, for the first quarter of 2008 were $7.0 ...

Orchid Cellmark Reports Fourth Quarter and Full Year 2007 Financial Results

... anticipated decrease in our U.K. agricultural revenue due to a government policy change to test only male sheep under the U.K. government National scrapie Plan." Mr. Bologna concluded, "All in all, I believe we are making good progress on many fronts but the very nature of our business is such that ...

American Chemical Society's weekly PressPac -- Feb. 27, 2008

... Chemistry, a semi-monthly journal. Prions are infectious proteins that can cause deadly nerve-damaging diseases such as Mad Cow Disease in cattle, scrapie in sheep, and a human form of Mad Cow Disease called variant Creutzfeldt-Jakob Disease. Conventional tests are designed to detect the proteins only ...

Researchers Develop Resin Beads That Capture Mad Cow Disease Agent From Blood

... Creutzfeldt-Jakob disease, mad cow disease, scrapie and other prion diseases in animals – during ... resin-filtered blood were infected with scrapie by the end of the 550-day test. Fifteen of 99 ... at the end of the testing period. No evidence of scrapie was discovered in brains of hamsters that were ...

Mad Cow Disease Has Roots Traceable To Man

... case or cases of BSE is currently unknown. Sheep scrapie or a previously undetected bovine transmissible ... India states: “So far not a single case of BSE or scrapie had been reported from India, except for one case of scrapie from the Himalayan foothills in a sheep, which ...

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Scrapie in Medical Technology

Variant of Mad Cow Disease May Be Transmitted by Blood Transfusions, According to Animal Study

... BSE or scrapie; the BSE donors were experimentally infected, while the scrapie donors had naturally acquired the disease. While scrapie is not thought to ... blood donors. The outcome of the experiment showed that both BSE and scrapie could be effectively transmitted between sheep by blood transfusion. ...
Scrapie in Medical Dictionary

Scrapie

... More on scrapie Prion - unidentified infectious agent thought ... s -- kuru of the Fore people of New Guinea and scrapie of ... The most widespread TSE in animals is scrapie , a disease that has affected sheep and goats ...

Creutzfeldt

... disease felt to possibly be transmitted through blood . Well-known prion diseases are Creutzfeldt -Jakob disease (CJD) and kuru in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE), also called " mad cow disease ," in cattle, and chronic wasting disease in deer and elk ...

Mad Cow Disease

... disease felt to possibly be transmitted through blood . Well-known prion diseases are Creutzfeldt-Jakob disease (CJD) and kuru in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE), also called " mad cow disease ," in cattle, and chronic wasting disease in deer and elk ...
Scrapie in Biological News

Orchid Cellmark Reports Third Quarter 2008 Financial Results

... compared to a year ago was due to lower volumes of animal DNA testing for scrapie susceptibility and slightly reduced forensics revenues due to adverse ... a challenging industry environment where pricing pressures, declining U.K. scrapie orders and adverse foreign exchange rates all contributed to the revenue ...

Tracking down the cause of mad cow disease

... of the normal form of the protein into its pathogenic form, which causes scrapie and mad cow disease. A team headed by Christian F. W. Becker at the TU ... of membrane association on conversion of the protein into the pathogenic scrapie form. This should finally make it possible to track down the infectious ...

Scripps scientists develop new tests that identify lethal prion strains quickly and accurately

... One of the new in vitro tests, called the Standard scrapie Cell Assay, measures prion infectivity levels in a highly accurate and ... for them to become lethally infected. In contrast, the new Standard scrapie Cell Assay is based on prion-susceptible cell lines. In the test, cells ...

Lymph nodes can be key in spreading prion infectivity

... infective prion agents -the pathogens responsible for conditions such as scrapie and Creutzfeldt-Jakob disease - into the nervous system, according to new ... lymph nodes that is part of the body's defence system - in the spread of scrapie infection to nerve tissue in hamsters. The team discovered that if a lymph ...

Redefining what it means to be a prion

... have identified a small number of other prions in humans and other animals, most of which cause degenerative neurological diseases, including scrapie in sheep and goats, and Creutzfeldt-Jakob disease in humans. A few prions have also been found in model organisms, such as yeast. Believing the ...

Iron is involved in prion disease-associated neuronal demise

... prion disorders are sporadic, inherited, and infectious, and affect both humans and animals; common examples are mad cow disease in cattle, scrapie in sheep, and Creutzfeldt-Jakob disease in humans. The causative agent is a misfolded protein referred to as PrP-scrapie that replicates itself by ...

Common soil mineral degrades the nearly indestructible prion

... DNA and RNA, prions are believed to cause such fatal brain ailments as chronic wasting disease (CWD) in deer and moose, mad cow disease in cattle, scrapie in sheep and Creutzfeldt-Jakob disease in humans. In addition to being perhaps the weirdest infectious agent know to science, the prion is also the ...

Prions and retroviruses -- an unholy alliance?

... work as a trigger to a set of diseases of the brain and nervous system, the so-called spongiform encephalopathies. These include BSE in cattle, scrapie in sheep and Creutzfeldt Jakobs Disease in humans. Prions are structural variants of a normal protein found in healthy tissues especially in the ...

New approach to BSE successful in lab

... slow down the progress of the fatal brain disease scrapie in mice. This has been established by researchers ... awarded this year’s Nobel Prize for Medicine. scrapie is a variant of the cattle disease BSE and the ... yet there is no cure. In mice suffering from scrapie the pathogenic prion protein is known as PrP-Scr, ...

New evidence questions the simple link between prion proteins and madcow disease

... with different degrees of genetic resistance to scrapie ?the sheep form of the disease. When they ... gut with a fluid mixture containing 0.5 grams of scrapie infected brain containing a large amount of the ... just a secondary marker of the presence of the scrapie agent," says Jeffrey. His belief in this need ...

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Scrapie in Biological Technology

The Bio-Rad Silver Stain, Rev E

... 82, 80628066 (1985) 66. Oesch B et al., A cellular gene encodes scrapie PrP 27-30 protein, Cell 40, 735746 (1985) 67. Palumbo ... SB et al., Purification and structural studies of a major scrapie prion protein, Cell 38, 127134 (1984) 70. Pytela R et al., A ...
Scrapie in Biological Definition

Prion

... encephalopathy diseases (TSEs) , including scrapie (a disease of sheep ), kuru (found in members ... to 'cellular' PrP, while the 'SC' refers to ' scrapie ', a prion disease occurring in sheep). It is ... Natural host Prion name PrP isoform scrapie Sheep and goats ...
Scrapie in Biological Dictionary

Quaternary structure

... Structure . Quaternary Structure . Complex ... Quaternary Structure ... Quaternary structure and amyloid. X-ray Diffraction of scrapie Prion. Interactive prion models ... Certainly, the quaternary structure has a modulating ... TUTORIAL ON PEPTIDE AND PROTEIN STRUCTURE . ....

Prion

... diseases in cows, sheep, humans, and. Prion diseases are transmissible neurodegenerative conditions that affect the ... Prion diseases include scrapie (a disease of sheep), chronic wasting disease (in ... Normal forms of these prion protein molecules reside on the surface of many ... Prion ...
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