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Recombinase in Medical News

Potential Cure for HIV Discovered

... he wrote. "Although favorable results would represent perhaps only a baby step toward eventual use in patients, the discovery of the Tre recombinase proves that enzymatic removal of integrated HIV-1 from human chromosomes is a current-day reality," he said. The researchers who developed ...
Recombinase in Biological Technology

Mammalian Expression Vectors with Interchangeable Selectable Markers

... pExchange core expression vector, drug-resistance modules and Cre recombinase protein. The pExchange core vectors are based on the pCMV-Script ... This reaction is followed by heat inactivation of Cre recombinase at 65C for 15 to 30 minutes. The inactivated recombination ...
Recombinase in Biological Products

* Quick & Easy E. coli Gene Deletion Kit from Gene Bridges GmbH

Description:... The use of an FRT-flanked resistance cassette for the replacement of the targeted gene allows the subsequent removal of the selection marker by a Flp recombinase step, if required. Flp expression plasmids can be purchased from Gene Bridges. Multiple knockouts can be generated either by a repetitive insertion ...
Company:Gene Bridges GmbH

* Quick & Easy Conditional Knock Out Kit - FRT from Gene Bridges GmbH

Description:... promoter (PGK) for expression of neomycin resistance in mammalian cells. The included pCI-FLPe expression plasmid codes for an improved Flp recombinase which shows a four to tenfold higher recombinational activity compared to the wildtype Flp enzyme at temperatures between 37C (optimal growth ...
Company:Gene Bridges GmbH
Recombinase in Biological Definition

Genetic recombination

... of genetic information. Chemistry of crossover Enzymes known as recombinases catalyze the reactions that allow for crossover to occur. A recombinase creates a nick in one strand of a DNA double helix, allowing the nicked strand to pull apart from its complementary strand and anneal to one ...
Recombinase in Biological Dictionary

Recombinase

... Cre recombinase , often abbreviated to Cre, is a Type I ... recognition element is a 34 base ... recombinase . From Wikipedia, the free encyclopedia. Jump ... from "http://en.wikipedia.org /wiki/ recombinase " Categories: Genetics stubs ... I. ...

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