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Purpura in Medical News

Novel therapeutic approaches may improve patient outcomes in several platelet disorders

... previously untreated idiopathic thrombocytopenic purpura (ITP), an investigational oral treatment for ... previously untreated idiopathic thrombocytopenic purpura (ITP). The results of this study indicate that ... Patients With Chronic Idiopathic Thrombocytopenic purpura (ITP): Results of a Phase III, Double-Blind, ...

PROMACTA(R) (eltrombopag) RECEIVES UNANIMOUS RECOMMENDATION BY FDA ADVISORY PANEL

... Treatment of Chronic Idiopathic Thrombocytopenic purpura (ITP) CHICAGO, May 30 /PRNewswire-USNewswire/ ... patients with chronic idiopathic thrombocytopenic purpura (ITP). The FDA advisory committee was held ... of adult chronic idiopathic thrombocytopenic purpura (ITP). J Thromb Haemost. 2008 doi: ...

GlaxoSmithKline Files for FDA Approval of PROMACTA(TM) (eltrombopag) to be the First Oral Platelet Growth Factor for Rare Blood Disorder

... with Chronic Idiopathic Thrombocytopenic purpura (ITP) PHILADELPHIA and LONDON, Dec. 20 ... patients with chronic idiopathic thrombocytopenic purpura (ITP) to increase platelet counts and reduce ... Medicine. About Idiopathic Thrombocytopenic purpura There are estimated to be between 50,000-100,000 ...

Einstein scientists propose new theory of autism

... that are involved in complex cognitive tasks," says Dr. Mehler. Drs. purpura and Mehler hypothesize that in autism, the LC-NA system is dysregulated by ... at mid-gestation resulted in the highest prevalence of autism. Drs. purpura and Mehler believe that, in autistic children, fever stimulates the LC-NA ...

Research Highlights New Approaches to Management of Blood Clotting and Bleeding Disorders

... counts in splenectomized patients with chronic immune thrombocytopenic purpura in phase III study [Abstract #2] Terry Gernsheimer, MD, Puget Sound ... in previously splenectomized patients with chronic immune thrombocytopenic purpura (ITP) per ASH guidelines and baseline platelet counts <30,000/µL. Chronic ...

Rigel R788 Raises Platelet Counts in Immune Thrombocytopenic Purpura (ITP) Patients in Phase 2 Study

... novel, oral Syk kinase inhibitor, in patients with Immune Thrombocytopenic purpura (ITP). The single-center, open-label, dose-escalating study showed that ... 2007, from 9:00a.m. - 7:30p.m., in Atlanta, GA. Immune Thrombocytopenic purpura ITP affects approximately 200,000 people in the U.S., with an ...

New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia

... for aspiration pneumonia. Priapism has been reported. Severe priapism may require surgical intervention. Thrombotic Thrombocytopenic purpura (TTP) has been reported. Administration: Care should be taken to avoid inadvertent injection into a blood vessel. Suicide: The ...

FDA Grants Approval for Use of RISPERDAL(R) CONSTA(R) as Both a Monotherapy and Adjunctive Therapy in the Maintenance Treatment of Bipolar I Disorder

... for aspiration pneumonia. Priapism has been reported. Severe priapism may require surgical intervention. Thrombotic Thrombocytopenic purpura (TTP) has been reported. Administration: Care should be taken to avoid inadvertent injection into a blood vessel. Suicide: The ...

3SBio Inc. Files for SFDA Approval for TPIAO Label Extension for the Treatment of ITP

... with the Chinese State Food and Drug Administration (SFDA) for approval of a TPIAO label extension for the treatment of idiopathic thrombocytopenic purpura (ITP) in China. If the extension is approved, 3SBio expects that TPIAO for ITP will be the only treatment of this kind available in China. ...

Rigel to Webcast Investor Update on October 27, 2008

... being evaluated in two Phase 2b clinical trials in patients with rheumatoid arthritis, as well as Phase 2 clinical trials in immune thrombocytopenic purpura and B-cell lymphomas. The event will be webcast live and can be accessed from Rigel's website at http://www.rigel.com . Please connect to Rigel's ...
Purpura in Medical Technology

Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders

... previously untreated idiopathic thrombocytopenic purpura (ITP), an investigational oral treatment for ... previously untreated idiopathic thrombocytopenic purpura (ITP). The results of this study indicate that ... Patients With Chronic Idiopathic Thrombocytopenic purpura (ITP): Results of a Phase III, Double-Blind, ...

Long-Term Safety and Efficacy Data on Promacta(TM) (Eltrombopag) Presented at American Society of Hematology Annual Meeting

... patients with chronic idiopathic thrombocytopenic purpura increased and maintained platelet counts ... treatment of chronic idiopathic thrombocytopenic purpura (ITP).(1) These preliminary results from ... of subjects with idiopathic thrombocytopenic purpura (ITP): preliminary data from the EXTEND ...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

... (romiplostim) in adult patients with chronic immune thrombocytopenic purpura (ITP). Chronic ITP is a chronic and serious autoimmune disorder ... in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient response to corticosteroids, ...

FDA Approves Promacta(R) (Eltrombopag), the First Oral Medication to Increase Platelet Production for People With Serious Blood Disorder

... in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient response to corticosteroids, ... D. Prevalence estimates of adult chronic idiopathic thrombocytopenic purpura (ITP). J Thromb Haemost. 2008; 6(4): 711 - 712. ...

FDA Grants Priority Review for PROMACTA(R) (eltrombopag)

... short-term treatment of patients with chronic idiopathic thrombocytopenic purpura (ITP). PROMACTA is an investigational, once-daily oral treatment that ... D. Prevalence estimates of adult chronic idiopathic thrombocytopenic purpura (ITP). J Thromb Haemost. 2008 doi: ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... for aspiration pneumonia. Priapism has been reported. Severe priapism may require surgical intervention. Thrombotic Thrombocytopenic purpura (TTP) has been reported. Administration: Care should be taken to avoid inadvertent injection into a blood vessel. Suicide: The ...

Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

... granted marketing authorisation for Nplate(R) (romiplostim) for the treatment of splenectomised adult chronic immune (idiopathic) thrombocytopenic purpura (ITP) patients who are refractory to other treatments (e.g. corticosteroids, immunoglobulins). Nplate may be considered as second line treatment for ...

GSK Reports PROMACTA(R) (eltrombopag) Significantly Increased Platelet Counts and Reduced Bleeding in Long-Term Study of Patients With Chronic ITP

... . Accessed November 12, 2007. 2. Feudjo-Tepie M, Robinson N, Bennett D. Prevalence estimates of adult chronic idiopathic thrombocytopenic purpura (ITP). J Thromb Haemost. 2008; 6(4): 711 - 712. ...

Nplate(TM) (Romiplostim) Receives Positive Opinion for Marketing Authorisation in the European Union

... for Nplate(TM) (romiplostim) in the European Union (EU). The CHMP recommends Nplate for adult chronic immune (idiopathic) thrombocytopenia purpura (ITP) splenectomised patients who are refractory to other treatments (e.g. corticosteroids, immunoglobulins). Nplate may be considered as second ...

Rigel's R788 Slows Progression of Murine Lupus in Preclinical Studies

... syk kinase inhibitor, which has shown clinically significant results in treating patients with rheumatoid arthritis and immune thrombocytopenic purpura in clinical trials. A third clinical trial of R788 in patients with B-cell lymphoma will be completed later this year. Rigel also expects to initiate ...
Purpura in Medical Definition

Hematopathology

... aplasia , Fanconi anemia ) • Hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , C ) • Von Willebrand disease • purpura ( Henoch-Schönlein , ITP , TTP ) other Methemoglobinemia - Langerhans cell histiocytosis ...

Pathology

... aplasia , Fanconi anemia ) • Hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , C ) • Von Willebrand disease • purpura ( Henoch-Schönlein , ITP , TTP ) other Methemoglobinemia - Langerhans cell histiocytosis v • d • e ...
Purpura in Medical Dictionary

Aging skin

... ( ecchymosis ) Idiopathic thrombocytopenic purpura (petechiae and purpura ) Henoch -Schonlein purpura ...

Ecchymosis

... ( ecchymosis ) Idiopathic thrombocytopenic purpura (petechiae and purpura ) Henoch -Schonlein purpura ...

Henoch

... Henoch -Schonlein purpura on an infant 's foot Henoch -Schonlein purpura on an infant 's legs Henoch -Schonlein purpura on an infant 's legs ... HENOCH -SCHONLEIN ...

Itp

... Disorders What is idiopathic thrombocytopenic purpura ( ITP )? ITP does not cause symptoms as ... of ITP : ... Idiopathic Thrombocytopenic purpura ( ITP ). In about one in 22,300 doses, MMR can ... disorder called idiopathic thrombocytopenic purpura ( ITP ). CBP-1011 (medroxy progesterone ...

Purpura

... purpura Definition: purpura is purplish discolorations in the skin ... vessels near the surface of the skin . purpura may also occur in the mucous membrane s (such ...

Abdominal Pain

... constipation , wind , abdominal pain and headaches . ANAPHYLACTOID purpura - This relatively rare disorder is characterized by skin purpura , joint pain s, abdominal pain , and renal disease ( ...

Anaplastic thyroid cancer

... thyroid cells. anastomosis (an-AS-ta-MO-sis) ... Anaphylactoid purpura ( Henoch -Schonlein purpura ) Anaphylaxis An aplastic Carcinoma of the Thyroid ( Anaplastic ...

Antepartum

... , amniotic embolism ) Prostate cancer Shock Thrombocytopenia purpura ... Extensive vascular ( blood vessel) trauma or surgery ... mole , amniotic embolism ) Prostatic cancer Shock Thrombocytopenia purpura ... ...

Factor II deficiency

... X deficiency Factor XII deficiency Idiopathic thrombocytopenic purpura ( ITP ) Thrombotic thrombocytopenic purpura Drug -induced immune thrombocytopenia ... ...

Hemophilia

... X deficiency Factor XII deficiency Idiopathic thrombocytopenic purpura ( ITP ) Thrombotic thrombocytopenic purpura Drug -induced immune thrombocytopenia ... HEMOPHILIA : An ...

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Purpura in Biological News

Lancet study supports new, highly effective treatment for blood disorder

... diagnosed with chronic immune thrombocytopenic purpura (ITP), an autoimmune disease that dramatically ... with chronic immune (idiopathic) thrombocytopenic purpura who have had an insufficient response to ... in GlaxoSmithKline. Immune thrombocytopenic purpura (ITP) is an autoimmune disease in which ...

Eltrombopag effective for hepatitis C patients with low blood-platelet counts

... Medicine, finding the platelet growth factor successfully increased platelet counts and decreased bleeding in patients with Immune Thrombocytopenic purpura (ITP), an autoimmune disease that dramatically reduces the number of platelets in their blood. (Dr. Bussel is an Advisory Board Member for ...

U of M researcher examines newly emerging deadly disease

... a newly emerging illness, named staphylococcal purpura fulminans. The disease begins as a respiratory ... leading to death due to hypertension and shock. purpura fulminans has been identified in five cases in ... known cases, only two patients have survived. purpura fulminans is an acute illness commonly associated ...
Purpura in Biological Technology

Amgen's Third Quarter 2008 Adjusted Earnings Per Share Increased 14 Percent to $1.23

... for the treatment of thrombocytopenia in splenectomized (spleen removed) and non-splenectomized adults with chronic immune thrombocytopenic purpura (ITP). Nplate, the first FDA-approved peptibody protein, works by raising and sustaining platelet counts, representing a novel approach for the ...

3SBio Inc. Announces Second Quarter 2008 Results

... options. TPIAO for ITP We have achieved our enrollment goal for the Phase III trial for TPIAO for the treatment of idiopathic thrombocytopenic purpura (ITP). We remain on track to file the application for approval with the SFDA in the fourth quarter of 2008. TPIAO Phase IV Studies To maximize ...

ProMetic announces Octapharma publication of PRDT'S prion removal resin in Octaplas(R) manufacturing process at 30th International Congress of the International Society for Blood Transfusion meeting in Macao SAR, China

... coagulation disorders - both congenital and acquired - where no specific coagulation factor concentrate is available, and thrombotic thrombocytopenic purpura ("TTP") - usually in conjunction with plasma exchange. Octaplas(R) is fully licensed in 29 countries worldwide, and roughly 6 million bags have been ...

Vermillion Announces First Quarter 2008 Financial Results and Business Progress

... tests are commercialized. During the first quarter of 2008, products revenue of $5,000 was generated from the sale of thrombotic thrombocytopenic purpura ("TTP") test component materials to The Ohio State University Research Foundation ("OSU"). Total operating expenses decreased in the first quarter ...

CSL Behring Signs Agreements With Canadian Blood Services and Hema-Quebec to Supply Life-Saving Therapies

... a period of 24 months. Privigen(R) is indicated for the treatment of primary and secondary immune deficiencies as well as immune thrombocytopenic purpura (ITP), a disorder characterized by low platelet counts due to the presence of auto-antibodies directed against the patient's own platelets. ...

Vermillion Summarizes Recent Accomplishments and 2007 Financial Results; Outlines 2008 Business Milestones

... clinical and commercial advancements in our diagnostic programs for peripheral artery disease (PAD), ovarian cancer and thrombotic thrombocytopenic purpura (TTP)," said Gail Page, President and CEO of Vermillion. "Our vision is to provide novel diagnostic tools to physicians in an effort to improve ...

3SBio Inc. Announces Unaudited Fourth Quarter and Fiscal Year 2007 Results

... and expect filing with SFDA in Q3 of 2008. The initial results of the Phase III trial for TPIAO for the treatment of idiopathic thrombocytopenic purpura (ITP) demonstrated excellent efficacy and a high safety profile based on our data to date. Enrollment has been completed, but we experienced a higher ...

FDA Approves New 300mg Loading Dose Tablet for PLAVIX(R) (clopidogrel bisulfate)

... REACTIONS.*) -- As part of the worldwide post marketing experience with PLAVIX, there have been cases of reported thrombotic thrombocytopenic purpura (TTP), some with fatal outcome. TTP has been reported rarely following use of PLAVIX, sometimes after a short exposure ( condition that ...
Purpura in Biological Dictionary

Thrombocytes

... the fluid systems, innate immunity ... leukocytes (white blood cells or WBCs), and thrombocytes (platelets) ... Idiopathic thrombocytopenic purpura (ITP) is a bleeding condition in which the ... Platelets also are called thrombocytes (THROM-bo-sites) ... What does it mean when a veterinarian ...
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