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Porphyria in Medical News

QLT announces 12-month results from Novartis sponsored MONT BLANC study evaluating standard-fluence Visudyne(R) combination therapy

... than the standard light dose used in this study. After treatment, patients should avoid direct sunlight for five days to prevent sunburn. People with porphyria should not be treated with Visudyne. About QLT QLT Inc. is a global biopharmaceutical company dedicated to the discovery, development and ...

QLT announces positive results from the evaluation of Visudyne(R) combination therapy

... to lower light doses being used in this study. After treatment, patients should avoid direct sunlight for five days to prevent sunburn. People with porphyria should not be treated with Visudyne. About QLT QLT Inc. is a global biopharmaceutical company dedicated to the discovery, development and ...

QLT announces interim results of radical study evaluating Visudyne combination therapy

... to lower light doses being used in this study. After treatment, patients should avoid direct sunlight for five days to prevent sunburn. People with porphyria should not be treated with Visudyne. About QLT QLT Inc. is a global biopharmaceutical company dedicated to the discovery, ...

New book by UCR biologist discusses 12 diseases that impacted humanity

... book , Sherman argues that the following dozen diseases shaped history and illuminated the paths taken in finding measures to control them: porphyria and hemophilia , which influenced the political fortunes of England, Germany, Russia and the United States Late blight , which spawned a wave ...

Study Unveils New Insight To The Madness Of King George III

... journal Cell that the nutritional component of porphyria involves a key master metabolic molecule, PGC-1 ... III’s hair contained arsenic, which can provoke porphyria attacks. PGC-1 alpha is a “transcriptional ... The findings suggest that patients with porphyria should avoid any drugs or foods that turn on ...

ABCB6 Is Key to Production of Heme in Hemoglobin

... triggers pain in the chest, abdomen, limbs or back, as well as paralysis, cramping and personality changes or mental disorders. 'Also, people with porphyria can suffer sudden, acute attacks if they take certain tranquilizers and other drugs that interfere with this system,' Schuetz said. 'So our work ...

Colour Of Urine Can Reveal The Health Status Of The Patients

... And gout can produce pink urine. This diagnostic tool goes back many centuries. The ancient Greeks first diagnosed the rare blood disorder porphyria by observing colourful urine and even named the illness after the Greek word for purple. Then in the Middle Ages, when urine analysis enjoyed ...

Arsenic May Have Been Responsible For The Madness Of King George III Of England

... contamination of his antimonial medications is the probable source of the arsenic. We propose that exposure to arsenic would exacerbate attacks of porphyria in a genetically predisposed individual. King George III was diagnosed to have suffered from Porphyria- a genetic defect leading to the faulty ...
Porphyria in Medical Technology

AMT Receives EMEA Orphan Drug Designation for Acute Intermittent Porphyria

... AMT-021 for the treatment of acute intermittent porphyria (AIP). Orphan Drug Designation for AIP ... disease." About Acute Intermittent porphyria Acute intermittent porphyria is a rare genetic disease in which mutations in ...

Amsterdam Molecular Therapeutics BV to present preclinical proof-of-concept data on its gene therapy AMT-020 to treat acute intermittent porphyria

... AMT-020 gene therapy to treat acute intermittent porphyria (AIP) at the Porphyrins and Porphyrias Congress, ... to protect patients suffering from recurrent porphyria attacks and/or neuropathy. AMT-020 is comprised ... an increasing dose of Pb for 4 days to induce a porphyria attack. The results showed that porphyric mice ...
Porphyria in Medical Products

Acute Intermittent Porphyria Enzyme

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories
Porphyria in Medical Dictionary

Acute porphyria

... ACUTE porphyria - A group of metabolic disorders that result ... of porphyrin or its precursors. Acute porphyria People with acute porphyria experience episodes of pain and disruption of ...

Hepatic

... hepatic bile duct cancer . Hepatic porphyria is an abnormal increase in pigments or colorings ... echinococcosis, hepatic ; ... porphyria cutanea tarda (PCT, cutaneous hepatic porphyria , or symptomatic ...

Porphyrins

... a series of steps into haem. A person with porphyria makes and excretes excessive amounts of ... heme in the blood . There are several kinds of porphyria . porphyria A disorder in which porphyrins build up in the ...

Porphyria

... porphyria Definition: porphyria is a group of inherited disorders involving ... (reddish muscle cell pigment), ... porphyria Definition ...

Symptomatic

... Long-lasting and severe, opposite of Acute . porphyria cutanea tarda (PCT, cutaneous hepatic porphyria , or symptomatic porphyria ): The most common type of ...

Erythropoietin

... erythropoiesis; erythropoietic; erythropoietic hormone ; erythropoietic porphyria ; erythropoietic proto porphyria ; erythropoietin ; ... Serum erythropoietin test: A test in which ...

Genetic Disorders

... International ] [ Search ] [ Ask the Doctor Forums ] ... Most cases of porphyria are caused by genetic disorders . Some cases are caused by toxic ... to lead . Menstruation may increase symptoms in women. Next section porphyria : Symptoms & Signs ... Genetics Understanding genetic factors and ...

Hereditary angioedema

... turn, affects blood vessels. Hereditary Angioedema Hereditary Copro porphyria ( porphyria ) Hereditary Deafness and Nephropathy ( Alport Syndrome ) Hereditary ...

Paints

... feet) or in airplanes. Although uncommon, some people have heard of porphyria because it is thought to have affected the English royal family hundreds ... madness of King George III. However, this paints an unfair picture of porphyria that ... Keep paints , pesticides and fertilizers properly stored ...

Porphyrias

... person can expect long problem-free periods. ^ Top ... Non- acute porphyria s In non- acute porphyria s the primary problem is with the skin . Porphyrias are classified ...

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Porphyria in Biological News

Attacks of King George III's madness linked to key metabolism molecule

... mediates effects of nutrition on blood disease porphyria Dana-Farber Cancer Institute researchers say ... issue of Cell that the nutritional component of porphyria involves a key master metabolic molecule, PGC-1 ... PhD, is lead author. "We've explained how porphyria symptoms can occur in episodic attacks triggered ...

ABCB6 is key to production of heme in hemoglobin

... triggers pain in the chest, abdomen, limbs or back, as well as paralysis, cramping and personality changes or mental disorders. "Also, people with porphyria can suffer sudden, acute attacks if they take certain tranquilizers and other drugs that interfere with this system," Schuetz said. "So our work ...
Porphyria in Biological Technology

Amsterdam Molecular Therapeutics Reports Full Year Results 2007

... trial in Canada on track - Appointment of Ferdinand Verdonck as chairman of supervisory board. - Global rights for acute intermittent porphyria treatment - Exclusive license to all gene therapy products from CIMA - Agreement with CIMA/Digna Biotech for AAV-mediated IGF-I treatment of late ...

Amsterdam Molecular Therapeutics Reports Half Year Results 2007

... Appointment of Ferdinand Verdonck as chairman of supervisory board. - Global rights for our product AMT 020 for the treatment of acute intermittent porphyria Results comparison Total revenues for the six months ended June 30, 2007, were EUR 50,000 compared to EUR 208,000 for the same period in 2006. The ...
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