Navigation Links
Polymorphisms in Medical News

Effectiveness of Progesterone in Reducing Preterm Births May Be Altered by Genetic Predisposition

... genetic variations known as single nucleotide polymorphisms (SNPs) in the human progesterone receptor gene ... treatment and genotype of 3 additional polymorphisms for non-African-American women delivering very ... award-winning study, The Relationship Between polymorphisms in the Human Progesterone Receptor and Clinical ...

Alcohol consumption and polymorphisms of cytochromes P4502E1 are high risks for ESCC

... related to the development of ESCC. The genetic polymorphisms of Cytochromes P4502E1 (CYP2E1), aldehyde ... conferred by CYP2E1, ALDH2 and ADH1B genetic polymorphisms on ESCC. Neither have a definition and evaluation ... We found there was synergetic interaction with polymorphisms of CYP2E1, ALDH2 genotype and heavy alcohol ...

Vanda Pharmaceuticals to Present New Data on Iloperidone at the 2007 American Society of Human Genetics Annual Meeting

... 1035 - Whole Genome Association Study Identifies polymorphisms in the NPAS3 Gene Associated with ... 1039 - Whole Genome Association Study Identifies polymorphisms in the CERKL Gene Associated with ... Schizophrenia POSTER 1040 - Single-Nucleotide polymorphisms in the CYP2D6 Gene Are Correlated ...

Scientists Spot Stroke Genes

... onto that information the genetic data, which was to look at 2.2 million polymorphisms across the genome in these participants," Fornage explained. "We identified two polymorphisms that were located in the same chromosomal region." The researchers ...

Genes May Decide Which Smokers Get Lung Disease

... of Medicine and Saint Louis University identified five single nucleotide polymorphisms (SNPs) -- human DNA sequence variations -- in ADAM33 that were more common ... studies will be needed to evaluate the biologic significance of these polymorphisms in the pathogenesis of COPD," wrote the authors of the study, which was ...

DNA differences may influence risk of Hodgkin disease

... M.D. Anderson Cancer Center in Houston evaluated the relationship between polymorphisms in five DNA repair genes (XPC, XPD, XPG, XRCC1, and XRCC3) in a population ... disease. The authors concluded that "these data suggest that genetic polymorphisms in DNA repair genes may modify the risk of Hodgkin disease especially when ...

More>>

Polymorphisms in Medical Technology

Researchers Develop New Procedure to Screen All 46 Human Chromosomes to Identify Abnormalities in Embryos

... aneuploidy screening in human blastomeres using single nucleotide polymorphisms (SNP)," provides fertility specialists for the first time with a rapid and ... approximately 250,000 different areas of the DNA, called single nucleotide polymorphisms (SNPs, or "snips") are individually examined and assigned a specific copy ...

Mayo Researchers Help Discover Genetic Cause for Primary Biliary Cirrhosis

... with primary biliary cirrhosis to those of 1,536 people who did not have the disease. Researchers looked at more than 300,000 single-nucleotide polymorphisms (SNPs), the most common genetic variations, among the approximately 11 million known to be present in the human genome. "There were significant ...

New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel

... (1) Mega J, Close S, Wiviott S, Shen L, Hockett R, Brandt J, Walker J, Antman E, Macias B, Braunwald E, Sabatine M, Cytochrome P450 Genetic polymorphisms and the Response to Prasugrel. Circulation. 2009 May 19 (2) Myrand SP, Sekiguchi K, Man MZ, Lin X, Tzeng RY, Teng CH, Hee B, Garrett M, ...

The Children's Hospital of Philadelphia: New Gene-Searching Method Uncovers Possible New Targets for Crohn's Disease Drugs

... the most significant gene variants associated with a given disease. Those variants, each a change in a single DNA base, are called single nucleotide polymorphisms (SNPs). However, individual GWA studies often do not have the statistical power to detect subtle but important variants that are involved in ...

St. Jude Finds More Than 100 Gene Variations Linked With Response to Leukemia Treatment

... the children inherited from their parents. The researchers then determined which of those small, inherited variations, called single-nucleotide polymorphisms (SNPs), were associated with minimal residual disease (MRD). MRD is the small number of leukemic cells that survive after remission induction therapy ...

Scientists Unmask Genetic Markers Associated With Psoriasis

... time by this study, and two more have since been confirmed by these researchers. Research details The team looked for single nucleotide polymorphisms (SNPs), or DNA changes, at 438,670 sites in 1,359 psoriasis cases and 1,400 healthy controls. Initial scans signaled differences in at least three ...
Polymorphisms in Medical Products

NanoChip Molecular Biology Workstation

Description:... Workstation is an automated multi-purpose instrument that facilitates detection of known sequences, such as in the analysis of Single Nucleotide polymorphisms (SNPs) and Short Tandem Repeats (STRs) using the NanoChip Electronic Microarray. The unique, open-architecture design permits researchers to define, ...
Company:Nanogen, Inc.

ABI PRISM 7900HT Sequence Detection System

Description:... requirements of todays drug discovery process. Key applications include gene expression quantitation and the detection of single nucleotide polymorphisms (SNPs) using the fluorogenic 5 nuclease assay. Real-Time Throughput: Over 5,000 sample wells per day with 384-well block configuration and ...
Company:Applied Biosystems

CEQ 8800 Genetic Analysis System

Features:... techniques. Quantitative analysis is possible by using an option to export the peak heights. Allow simultaneous analysis of single nucleotide polymorphisms at multiple sites of a template (or different templates). Delivers precise DNA sizing, accurate allele assignment and automated data review. ...
Company:Beckman Coulter, Inc.

CEQ™ 8800 Genetic Analysis System

Features:... techniques. Quantitative analysis is possible by using an option to export the peak heights. Allow simultaneous analysis of single nucleotide polymorphisms at multiple sites of a template (or different templates). Delivers precise DNA sizing, accurate allele assignment and automated data review. ...
Company:Beckman Coulter, Inc.
Polymorphisms in Medical Dictionary

Cough

... develops a sudden fever of 101F (38.3C) or higher develops unfamiliar, unexplained symptoms ... Cough lin SS, Hall IJ: A review of genetic polymorphisms and prostate cancer risk. Ann Epidemiol 12 (3): 182-96, 2002. [PUBMED Abstract] ... - Cough s persistently for longer than four or five days ...
Polymorphisms in Biological News

The genetics of fear: Study suggests specific genetic variations contribute to anxiety disorders

... polymorphisms are variations in genes which can result in ... in Germany examined the effect of specific polymorphisms on how fear is learned and how that fear is ... fear. In this study, the researchers focused on polymorphisms in two genes thought to play a role in anxiety ...

Effectiveness of progesterone in reducing preterm births may be altered by genetic predisposition

... genetic variations known as single nucleotide polymorphisms (SNPs) in the human progesterone receptor gene ... treatment and genotype of 3 additional polymorphisms for non-African-American women delivering very ... award-winning study, The Relationship Between polymorphisms in the Human Progesterone Receptor and Clinical ...

Researchers identify 4 genetic hotspots associated with psoriasis

... it confirmed findings we reported in 2007 of polymorphisms (mutations) in the IL-12/23 pathways. Third, we ... for psoriasis." This, plus the clustering of polymorphisms the IL-12/23 pathways, makes it apparent that ... of this is selecting from the more than10 million polymorphisms (mutations) in the human genome a group ...

Study identifies genetic variants giving rise to differences in metabolism

... Common genetic polymorphisms induce major differentiations in the metabolic make-up of the human ... interactions. The team identified four single nucleotide polymorphisms (SNPs) located in genes coding for well-characterized enzymes of the lipid ...

Sociological research shows combined impact of genetics, social factors on delinquency

... interaction of genetics and social influences and identified three genetic polymorphisms thatwhen examined in the context of modulating social controlsare ... expression may depend heavily on the environment." The three genetic polymorphisms that predict delinquency include: (1) the 30-base pair (bp) ...

Genes may play role in risk assessment for prostate cancer among Hispanics and caucasians

... samples to establish the relationship between the presence of genetic polymorphisms and the risk for prostate cancer. Specifically, they observed polymorphisms from the nuclear Vitamin D receptor (CDX2 and FokI), which modulates the ...

More>>

Polymorphisms in Biological Technology

Transgenomic Introduces SURVEYOR(R) Endonuclease Adaptor-Ligated Libraries (SEAL) for Determining Whole Genome Sequence Variation

... DNA, but is not limited to assessment of known common single nucleotide polymorphisms (SNPs). It thus bridges the current technology gap between haplotyping of ... all types of mismatches arising from the presence of single nucleotide polymorphisms (SNPs) or from small insertions or deletions. The protocol is based on the ...

Center for Molecular Medicine Selected to Provide DNA Analysis for Children's Oncology Group Leukemia Study

... of naturally occurring variations in human DNA, known as Single Nucleotide polymorphisms (SNPs), serve as signposts or markers in the genome. Associating these SNP ... annotated bio-specimen resources to identify and validate specific gene polymorphisms which can then be prospectively utilized to select specific anti-leukemia ...

New and Updated Online Tutorials for dbGaP, GAD, and DGV from OpenHelix

... a database of genotypes and phenotypes with extensive variation data and clinical details GAD is an annotated resource connecting human genes and polymorphisms to diseases and traits, and DGV or Database of Genomic Variants, catalogs and displays structural variation in the human genome. These three new ...

Data on WaferGen's SmartChip(TM) System to be Presented at 3rd Annual Rediscovering Biomarkers Conference

... the Institute for Genome Sciences and Policy at Duke University Medical Center. The focus of this program is the validation of single-nucleotide polymorphisms (SNPs) that are related to breast cancer, as well as an examination of the impact the validated SNPs have on patients' disease prognosis and response ...

Vanda Pharmaceuticals to Present Data on Fanapt(TM) and Tasimelteon at the 162nd American Psychiatric Association Annual Meeting

... associated with iloperidone efficacy on long term clinical outcome of patients who switch to iloperidone. NR1-058 Effect of polymorphisms in the dopamine receptor 2 gene on iloperidone efficacy for the treatment of patients with schizophrenia. NR7-009 Common effect of ...

deCODE and Celera Partner to Expand use of deCODE Risk Markers for Heart Attack, Stroke and Diabetes

... of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes," Nature Genetics (2006) 38, 320 - 323; Florez, et. al., "TCF7L2 polymorphisms and Progression to Diabetes in the Diabetes Prevention Program," N Engl J Med (2006); 355:241-250. Contacts: deCODE genetics Edward ...

More>>

Polymorphisms in Biological Products

ExcelGel DNA Analysis Kit from GE Healthcare, formerly Amersham Biosciences

Description:... ExcelGel DNA Analysis Kit, 1. *Fast, reproducible identification of DNA polymorphisms and high resolution DNA typing. *Semi-dry system offers fast and convenient set-up and clean-up. *Precast, plastic-backed gels and silver stain ...
Company:GE Healthcare, formerly Amersham Biosciences

SNP Discovery Service from Polymorphic DNA Technologies, Inc.

Description:... only data from the high resolution, high quality region of the DNA sequencing run are used. Our focus on this high quality region ensures that all polymorphisms are reliably detected, including heterozygotes. Simple and Competitive Price Structure Our price is competitive at just $.01 per base per sample, ...
Company:Polymorphic DNA Technologies, Inc.

P/ACE™ MDQ Molecular Characterization System from Beckman Coulter

Description:... system provides clear advantages over traditional electrophoresis for DNA quantitation (viral load, gene expression), mutation analysis, and size polymorphisms analysis. The easy-to-use system with microplate connectivity is ideal for basic research, method development, and quality control. The P/ACE ...
Company:Beckman Coulter
Polymorphisms in Biological Definition

Cancer

... as to mount an immune response against cancer-specific epitopes) and to potential venues for gene therapy for individuals with genetic mutations or polymorphisms that put them at high risk of cancer. Meanwhile, genetic testing for high-risk individuals, with enhanced surveillance or prophylactic surgery for ...

Human Genome Project

... identifying differences between individuals. Most of the current effort in identifying differences between individuals involves single nucleotide polymorphisms . Benefits Clear practical results of the project emerged even before the work was finished. For example, a number of companies, such as ...

Isozyme

... Although they have now been largely superseded by more informative DNA -based approaches (such as direct DNA sequencing , Single nucleotide polymorphisms and microsatellites ), they are still amongst the quickest and cheapest marker systems to develop, and remain (as of 2005 ) an excellent choice ...

Promoter

... study: Hobbs, K.; Negri, J.; Klinnert, M.; Rosenwasser, L.J.; and Borish, L. (1998). Interleukin-10 and transforming growth factor-beta promoter polymorphisms in allergies and asthma . Am J Respir Crit Care Med . 158 (6), 1958-1962. population genetics study: Burchard, E.G.; Silverman, E.K.; ...
Polymorphisms in Biological Dictionary

Polymorphisms

... types, such as the ABO system, are genetic polymorphisms . ... a range of polymorphisms . ... Polymorphism (biology), having ... of the same species, Influence of genetic polymorphisms , smoking, gender and age on CYP1A2 activity ... ...

AFLP

... ... Using Amplified Fragment Length polymorphisms (AFLPs) for genotyping and genome mapping ... ... technology has the capability to detect various polymorphisms in ... As a result, AFLP has ... AFLP ... technology has the capability to detect various polymorphisms in ... Technical tips, from Liscum Lab, ...

RFLP

... where restriction enzymes can RFLP . Restriction fragment length polymorphisms (RFLPs) were the first type of ... blotting with a probe specific for ... isozyme ... RFLP and Genetic Screening. Restriction fragment length polymorphisms ( RFLP ) have ... The first RFLP example will detect an individual with ...

MtDNA

... Eve book named this mtDNA haplogroup Helena. ... Genome database of polymorphisms and mutations of the human mitochondrial DNA. ... Submittal form for unpublished mtDNA polymorphisms ... In contrast to nuclear DNA, mtDNA follows maternal clonal ...

DGGE

... in. microbial ecology. ... DGGE blotting ... DGGE - finding polymorphisms with PCR amplified DNA ... For a DGGE polymorphism screen of unknown ... gradient Gel Electrophoresis for detection of single base changes polymorphisms genomic cloned and amplified DNA. New ideas about DGGE or questions ...

Simple Sequence Repeat

... analysis using anchored simple . sequence repeat primers has gained attention recently ... inheritance of inter- simple sequence repeat polymorphisms ... Comparison of the genomes of mouse and humans, repeat sequences ... There are four times more simple sequence repeats (caused by ...

More>>

Other Contents
(Date:8/21/2014)... born at a low birth weight puts black women at ... The findings may partly explain high diabetes rates among ... low birth weight, the researchers added. Their study of ... low birth weight were 13 percent more likely to develop ... The risk of diabetes was 40 percent higher in those ...
(Date:8/21/2014)... HealthDay Reporter THURSDAY, Aug. ... and antidepressants appears to best help people with severe ... out of five people suffering from severe depression for ... with cognitive therapy plus antidepressant medication, researchers found. ... better than drugs alone in helping people with mild ...
(Date:8/21/2014)... 2014 Transvaginal mesh lawsuits ... to move forward in the federal multidistrict litigation ... West Virginia, Bernstein Liebhard LLP reports. According to ... Court has established new stipulated evidence preservation protocols ... storage and preservation. (In re C.R. Bard Inc. ...
(Date:8/21/2014)... Seattle, WA chiropractors Dr. Lincoln Kamell ... and Massage Center have recently welcomed two new ... Lang, LMP and Mike Larios, LMP have specialized training ... and have developed their expertise working in a variety ... in a clinical environment where massage is used on ...
(Date:8/21/2014)... communities do not routinely screen women for intimate ... and public health researchers. Rural women who are ... they seek help., "Rural health care providers are ... McCall-Hosenfeld, a primary care physician and assistant professor ... College of Medicine. "However, in rural settings, it ...
Breaking Medicine News(10 mins):Health News:Low Birth Weights May Put Black Women at Risk for Diabetes 2Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 2Health News:Talk Therapy Plus Meds May Be Best for Severe Depression 3Health News:Transvaginal Mesh Lawsuits Move Forward in Federal C.R. Bard Litigation with Issuance of New Pretrial Order, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuits Move Forward in Federal C.R. Bard Litigation with Issuance of New Pretrial Order, Bernstein Liebhard LLP Reports 3Health News:Seattle’s Eastlake Chiropractic and Massage Center Is Pleased to Introduce Rina Lang and Mike Larios as New Members of Its Massage Therapy Team 2Health News:Seattle’s Eastlake Chiropractic and Massage Center Is Pleased to Introduce Rina Lang and Mike Larios as New Members of Its Massage Therapy Team 3Health News:Primary care physicians can be critical resource for abused women in rural areas 2
(Date:8/21/2014)... American singles found that during sex with a ... On average, men experience orgasm 85.1 percent of ... difference. For women, however, orgasm occurrence is less ... of the time during sex with a familiar ... sexual orientation, with lesbian women experiencing orgasm more ...
(Date:8/21/2014)... 2014 /PRNewswire-iReach/ -- LiveScan Service Provider  Binary ... a partnership with Gabriel Health Institute, one of ... Certified Nursing Assistant preparatory schools. The agreement ... member of Binary,s LiveScan service provider,s owner/operator team; ... its service capabilities by widening the service ...
(Date:8/21/2014)... window? It consists of radiations in the 3.3 to ... water in biological tissues. New theoretical findings show that ... water window. These could be the basis of an ... biological samples or to be used in high-precision spectroscopy. ... needed to efficiently generate the harmonic radiationswhich are multiples ...
Breaking Biology News(10 mins):Orgasm rates for single women less predictable than men's, vary by sexual orientation 2Orgasm rates for single women less predictable than men's, vary by sexual orientation 3Orgasm rates for single women less predictable than men's, vary by sexual orientation 4LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3Water window imaging opportunity 2
Other TagsOther Tags