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Polymerase in Medical News

WaferGen's Chief Scientific Officer to Deliver Executive Talk at Malaysian Ministry of Science, Technology and Innovation's PCR Conference

... Innovation's (MOSTI) biotechnology conference on polymerase chain reaction (PCR). The conference will be held ... as the conference's feature event, will focus on polymerase chain reaction (PCR) and highlight the history of ... as the inventor of Thermus aquaticus (Taq) DNA polymerase for use in PCR. About WaferGen ...

International Scientists Secure Quality in Molecular Diagnostics

... Consensus Guideline Reached For Quantitative polymerase Chain Reaction SALT LAKE CITY, March 31 ... laboratory method called qPCR (or quantitative polymerase chain reaction) was published by a group of ... PCR (qPCR): qPCR is an extension of the polymerase chain reaction invented in 1986 by Kary Mullis, ...

Anadys Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results and Highlights

... has been reported for any other non-nucleoside polymerase inhibitor. And today we are reporting that we ... ANA598 is an investigational oral non-nucleoside polymerase inhibitor that Anadys is developing for the ... has been reported for any other non-nucleoside polymerase inhibitor in a monotherapy study. A number of ...

Scientists identify key roadblock to gene expression

... on top of the transcription start site, so RNA polymerase must contend with that nucleosome as soon as it ... then soon pauses at the first nucleosome the RNA polymerase encounters. "This pause is maintained until ... removal of the nucleosome and encourage the RNA polymerase to continue along its path," said key ...

Urine Test for Chlamydia Shown Effective in Men

... infection is diagnosed by nucleic acid amplification tests, such as the polymerase chain reaction. But these tests are expensive, technically complex and can ... fast and accurate results in women. The new study compared the test to the polymerase chain reaction test using urine samples from more than 1,200 men, ages 16 ...

New Report Just Published: World Hepatitis C Virus And Therapeutics Market Report

... and Boceprevir II-7 Telaprevir and Boceprevir - A Comparison II-8 polymerase Inhibitors (PLIs) - Adding More Teeth to HCV Pipeline II-8 Viral Polymerases II-8 polymerase Inhibitor Drugs in Pipeline by Company, Category, and Development ...

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Polymerase in Medical Technology

Pharmasset Reports Positive Preliminary Antiviral Data With PSI-7851 for the Treatment of Hepatitis C

... (HCV). PSI-7851 is a second generation nucleotide polymerase inhibitor of HCV. PSI-7851 Phase 1 ... than Pharmasset's first generation nucleoside polymerase inhibitor, RG7128 (formerly known as R7128). In ... which act as alternative substrates for the viral polymerase thus inhibiting viral replication. We currently ...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

... R7227, protease inhibitor, and R7128, nucleoside polymerase inhibitor, shows significant potency in reducing ... an oral protease inhibitor and an oral nucleoside polymerase inhibitor resulted in significant HCV viral load ... with InterMune, and R7128, a nucleoside polymerase inhibitor, with Pharmasset. Further studies ...

ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients

... the Company's investigational non-nucleoside polymerase inhibitor, demonstrated potent antiviral activity ... to position ANA598 as a leading non-nucleoside polymerase inhibitor in development for the treatment of ... protease inhibitor telaprevir and the nucleoside polymerase inhibitor PSI-6130 are synergistic. These ...

ANA598 Demonstrates Potent Antiviral Activity in an Early Clinical Study in HCV-Infected Patients

... the Company's investigational non-nucleoside polymerase inhibitor. ANA598 was very well-tolerated and ... to position ANA598 as a leading non-nucleoside polymerase inhibitor in development for the treatment of HCV ... been reported previously for all classes of HCV polymerase inhibitors, including nucleosides. This ...

Anadys Pharmaceuticals Announces Single Dose Safety and Pharmacokinetics Results for ANA598 in Healthy Volunteers

... Results for Non-Nucleoside HCV polymerase Inhibitor Being Presented at AASLD SAN DIEGO, ... ANA598 as one of the leading non-nucleoside polymerase inhibitors currently in development for the ... investigational hepatitis C non- nucleoside polymerase inhibitor. ANA598 Phase I Study Results In ...

Anadys Pharmaceuticals Announces Successful Outcome of ANA598 Healthy Volunteer Study and Finalization of Study Design for Phase Ib Trial in HCV Patients

... Study of ANA598, a Non-Nucleoside NS5B polymerase Inhibitor, in Healthy Volunteers", will present ... Combinations of Antiviral Agents that Include HCV polymerase Inhibitor ANA598 have the Potential to Overcome ... inhibitor and a representative nucleoside polymerase inhibitor. About ANA598 Preclinical ...

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Polymerase in Medical Products

COBAS TaqMan Analyzer

Description:... Next-generation real-time polymerase chain reaction (PCR) testing for clinical laboratories. The COBAS TaqMan 48 Analyzer allows automated real-time amplification and detection of ...
Company:Roche Diagnostics

HLA SSP Trays

Description:... It is based on the principle that only primers whose sequence is completely complementary to a target sequence will be converted by the polymerase into PCR products. In contrast, non-complementary primers produce no amplification product. Using the Biotest SSP Kit Systems, reliable typing ...
Company:Biotest

HLA SSP Kits

Description:... It is based on the principle that only primers whose sequence is completely complementary to a target sequence will be converted by the polymerase into PCR products. In contrast, non-complementary primers produce no amplification product. Using the Biotest SSP Kit Systems, reliable typing ...
Company:Biotest

TaqScreen West Nile Virus Test

Description:... Roches patented polymerase chain reaction (PCR) technology, the worlds leading nucleic acid amplification technology, is an essential component of Roches blood screening assays ...
Company:Roche Molecular Systems, Inc.

HSV Non-Typing ASR

Description:... The HSV Non-Typing ASR contains primers and a FAM-labeled probe that is designed to detect a 92 bp region of the HSV Type 1 and Type 2 polymerase gene. This ASR requires an instrument that can detect a FAM reporter dye like the Cepheid SmartCycler System. The Cepheid Analyte Specific Reagent* ...
Company:Cepheid

Applied Biosystems 2720 Thermal Cycler

Description:... And because its cooling vents are in the back, you can safely place it in tight spaces to save valuable bench space. Practice of the patented polymerase chain reaction (PCR) process requires a license. The Applied Biosystems 2720 Thermal Cycler is an Authorized Thermal Cycler for PCR and may be used ...
Company:Applied Biosystems

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Polymerase in Medical Definition

Pathology

... aspirates. Molecular pathology refers to the use of nucleic acid-based techniques, such as in-situ hybridization, reverse-transcriptase polymerase chain reaction, and nucleic acid microarrays for specialised diagnostic studies of disease in tissues and cells. Autopsies are used to ...

Medicine

... of modern scientific medical knowledge and plays a large role in evidence-based medicine . Many modern molecular tests such as flow cytometry, polymerase chain reaction (PCR), immunohistochemistry , cytogenetics , gene rearragements studies and fluorescent in situ hybridization (FISH) fall within ...
Polymerase in Medical Dictionary

Anti

... INHIBITORS (NNRTIS): The third class of anti - HIV drugs, NNRTIs bind near reverse transcriptase's active site and subsequently inhibit its polymerase activity. Rarely, mild cases with few symptoms besides arthritis are treated with aspirin alone, although more powerful anti -inflammatory ...

Chill

... tachycardia . Not FDA approved. Bur chill SA, Lewis IJ, Abrams KR, et al.: Circulating neuroblastoma cells detected by reverse transcriptase polymerase chain reaction for tyrosine hydroxylase mRNA are an independent poor prognostic indicator in stage 4 neuroblastoma in children over ... chill ...

Gene

... Expression and DNA Repair Research Interest: Expression of mRNA in eukaryotic cells requires several dozen transcription factors in addition to RNA polymerase II. Gene therapy seems elegantly simple in its concept: supply the human body with a gene that can correct a biological malfunction that ...
Polymerase in Biological News

Molecular typesetting -- proofreading without a proofreader

... machines called RNA polymerases. "The RNA polymerase acts like an old fashioned newsprint typesetter, ... assembling letters one at a time. Similarly, RNA polymerase constructs RNA by reading the DNA and adding new ... explains Dr Cohen. There's no way for the RNA polymerase to ensure that the correct letter is always ...

New piece found in the puzzle of epigenetics

... fine regulation of the cell nucleus enzyme RNA polymerase II. This transcribes the genetic information of ... basis for protein synthesis. At the same time RNA polymerase II is also responsible for the production of ... had observed that a certain region of the RNA polymerase II enzyme the carboxy-terminal domain is ...

TRAPping proteins that work together inside living cells

... polymerase, a well-studied machine in cells. The polymerase is made up of many proteins that cooperate to translate DNA. One of the polymerase proteins has a tail that is known to touch the DNA and some helper proteins just before the polymerase starts translating. No one knew if this tail -- ...

Properties of unusual virus revealed in research

... called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The ... phages then use the host bacterial cell's RNA polymerase to synthesize messenger RNA through a process ... It injects both its own DNA and its own RNA polymerase into bacterial cells, so it can begin the process ...

Researchers study virus with unusual properties

... called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The ... phages then use the host bacterial cell's RNA polymerase to synthesize messenger RNA through a process ... It injects both its own DNA and its own RNA polymerase into bacterial cells, so it can begin the process ...

New antibiotic candidates from Braunschweig

... the natural substances block the bacterial RNA polymerase in a new manner: the natural substances append to another location within the RNA polymerase than the antibiotics previously investigated. ... of action the active substances prevent the RNA polymerase from adhering to the DNA reading of the genetic ...

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Polymerase in Biological Technology

Anadys Pharmaceuticals Receives FDA Clearance of Phase II Protocol to Study ANA598 in Combination With Interferon-Alpha and Ribavirin in HCV Patients

... as well as representative HCV protease and polymerase inhibitors. Furthermore, ANA598 retains full ... resistance to protease inhibitors, nucleoside polymerase inhibitors and non-nucleoside polymerase inhibitors that act at binding sites distinct ...

Anadys Pharmaceuticals Reports First Quarter 2009 Financial Results and Highlights

... ANA598 is an investigational oral non-nucleoside polymerase inhibitor that Anadys is developing for the ... Activity of ANA598, a Potent Non-Nucleoside polymerase Inhibitor, In Chronic Hepatitis C Patients," at ... protease inhibitor telaprevir and the nucleoside polymerase inhibitor PSI-6130 are synergistic. These ...

Idenix Pharmaceuticals Reports Data From Three Hepatitis C Development Programs at the 44th Annual Meeting of the European Association for the Study of the Liver

... data on IDX184, a once-daily, oral nucleotide polymerase inhibitor prodrug currently being evaluated in a ... two clinical candidates: IDX375, a non-nucleoside polymerase inhibitor and IDX316, a protease inhibitor, both ... therapy." IDX184 Nucleotide Prodrug polymerase Inhibitor IDX184 is a liver-targeted, oral ...

INFORM-1 Clinical Trial Amended to Further Explore Promising Direct Antiviral Regimen in HCV Patients

... ITMN-191 (R7227) in combination with nucleoside polymerase inhibitor R7128 (Roche/Pharmasset), referred to ... (ITMN-191), a protease inhibitor, and R7128, a polymerase inhibitor, in 14 days of combination therapy. ... Pharmasset, Roche is developing R7128, an HCV RNA polymerase inhibitor, also for therapy in combination with ...

Idenix Announces Data Presentations from Three HCV Discovery and Development Programs at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL)

... ACTIVITY OF THE LIVER-TARGETED NUCLEOTIDE HCV polymerase INHIBITOR IDX184 CORRELATES WITH TROUGH SERUM ... IDX184, A LIVER-TARGETED NUCLEOTIDE HCV polymerase INHIBITOR: RESULTS OF A FIRST-IN-MAN SAFETY AND ... OF IDX375, A NOVEL AND POTENT NON-NUCLEOSIDE HCV polymerase INHIBITOR - Abstract #1442; Poster ...

ANA598 Receives Fast Track Designation From the FDA for the Treatment of Chronic Hepatitis C Infection

... investigational hepatitis C non-nucleoside polymerase inhibitor. Anadys is currently enrolling ... review of ANA598, one of the few non-nucleoside polymerase inhibitors in clinical development for the ... complementary agents, ANA598, a non-nucleoside polymerase inhibitor and ANA773, an oral TLR7 agonist ...

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Polymerase in Biological Products

MasterAmp Taq DNA Polymerase Kit from EPICENTRE Biotechnologies

Description:... MasterAmp™ Taq DNA polymerase is a thermostable DNA polymerase derived from Thermus aquaticus. Having optimal ... exonuclease activity. MasterAmp Taq DNA polymerase is highly purified using a proprietary procedure ...
Company:EPICENTRE Biotechnologies

AccuPrime Pfx from Invitrogen

Description:... AccuPrime™ Pfx DNA polymerase is ideal for high-fidelity amplification of DNA ... enzyme preparation containing recombinant DNA polymerase from Pyrococcus sp. with proofreading (3'Cut Site5' exonuclease) activity. Platinum Anti-Pfx DNA polymerase antibodies ...
Company:Invitrogen

BioTherm Taq DNA Polymerase from eEnzyme LLC

Description:... BioTherm DNA polymerase is a thermostable DNA polymerase purified from the Thermus aquaticus strain in ... isolation of thermostable enzymes processing DNA polymerase activity from thermophilic bacteria. ...
Company:eEnzyme LLC

Klenow Fragment, Exonuclease Minus from Promega

Description:... DNA polymerase I Large (Klenow) Fragment, Exonuclease Minus, is a DNA-dependent DNA polymerase that lacks both the 5´→3´ and the ... activities present in intact E. coli DNA polymerase I (1,2). It is used for random primer labeling ...
Company:Promega

DNA Polymerase I Large (Klenow) Fragment from Invitrogen

Description:... DNA polymerase I Large (Klenow) Fragment is a DNA polymerase that lacks the 5'Cut Site3' exodeoxyribonuclease activity of intact DNA polymerase I but it contains the 3'Cut Site5' ...
Company:Invitrogen

Expand High Fidelity PLUS PCR System; Thermostable DNA polymerase mixture from Roche Applied Science

Description:... PCR Blends. This new blend combines Taq DNA polymerase with a novel proofreading protein isolated and ... mediates proofreading activity, but has no polymerase activity itself. The synergy between the ... protein and the processivity of Taq DNA polymerase is the key to Expand High FidelityPLUS Enzyme ...
Company:Roche Applied Science

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Polymerase in Biological Definition

Molecular biology

... biology 2.1 Expression cloning 2.2 polymerase chain reaction (PCR) 2.3 Gel electrophoresis ... drugs against the protein can be studied. polymerase chain reaction (PCR) Main article: polymerase chain reaction The ...

Polymerase chain reaction

... polymerase Chain Reaction (PCR) is a molecular biological ... of duplication driven by an enzyme called DNA polymerase . DNA polymerase occurs naturally in living organisms, where it ...

Primer

... strand of RNA . This RNA is produced by an RNA polymerase , and is later removed and replaced with DNA by a ... DNA polymerases, such as DNA sequencing and polymerase chain reaction (PCR), require primers. The ... as a start marker for the chain reaction. In polymerase chain reaction (PCR), primers are used to ...

Protein biosynthesis

... . The transcription starts with initiation. RNA polymerase , an enzyme, binds to a specific region on the ... starting point, called the promoter . As the RNA polymerase binds on to the promoter, the DNA strands are ... second process is known as elongation. As the RNA polymerase travels through the strand that is opposite to ...

Enzyme

... the word ending in "-ase". Examples are alcohol dehydrogenase and DNA polymerase . Kinases are enzymes that transfer phosphate groups. The ... compounds Phenylalanine hydroxylase (PAH): Phospholipase polymerase : builds long chains of nucleic acid polymers from their constituents ...

Lac repressor

... the cell to reduce production. The first step in production is for RNA polymerase to make RNA from a stretch of DNA. DNA can be thought of as a highway , with entrances and exits. The enzyme RNA polymerase is like a car . For a specific protein sequence to be made, the car ...

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Polymerase in Biological Dictionary

Taq polymerase

... Taq polymerase is a thermostable DNA polymerase named after the thermophilic bacterium Thermus ... " Taq Pol", and is frequently used in polymerase chain reaction ... What is Taq ...

T7 RNA Polymerase

... T7 RNA polymerase is an RNA polymerase that catalyzes the formation of RNA in the 5'→ 3' direction. T7 polymerase is extremely promoter-specific and only ...

Sub-cloning

... Cloning Taq polymerase PCR products by T/A cloning : Taq polymerase has an ... Therefore, I recommend using a ... SLIC Sub - cloning using T4 DNA polymerase treated inserts with RecA ... We describe a ...

SnRNA

... of eukaryotic cells. They are transcribed by RNA polymerase II or RNA polymerase III and are involved in a variety of important ... of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining ... The U4 ...

Small nuclear RNA

... eukaryotic cells. They are transcribed by RNA polymerase II or RNA polymerase III and are involved in a variety of important ... of transcription factors (7SK RNA ) or RNA polymerase II (B2 RNA ), and maintaining ... Aspects ...

Sigma Factor

... factor that enables specific binding of RNA polymerase to gene promoters. Different sigma factors ... Bioinformatics Institute ... IPR013324 RNA polymerase sigma factor , regions 3 and 4 ... An ... phase (in response to the stress of ... polymerase sigma -70 factor 119 ... Alternative ...

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Other Contents
(Date:8/19/2014)... 19, 2014 Kars4Kids , a ... announced today its partnership with New York State Senator ... in the Bronx. The giveaway will take place in ... Crotona Park on August 22. , “With a ... believe properly preparing children for school with the necessary ...
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(Date:8/19/2014)... York (PRWEB) August 19, 2014 As ... Bernstein Liebhard LLP notes the publication of a new ... may increase the risk of acute kidney injury in ... Ottawa Citizen, the study was conducted by researchers at ... the Institute for Clinical Evaluative Sciences, and looked at ...
Breaking Medicine News(10 mins):Health News:Backpack Giveaway Kars4Kids Partners with New York State Senator Gustavo Rivera to Prepare Bronx Students for New School Year 2Health News:Top10BestSEOHosting.com: Cheap Joomla Hosting Reviews Unveiled 2Health News:GrandeLINER™ Wins Independent Cosmetics Manufacturers & Distributors Award 2Health News:GrandeLINER™ Wins Independent Cosmetics Manufacturers & Distributors Award 3Health News:Certain Antipsychotic Meds Tied to Kidney Problems in Elderly 2Health News:Certain Antipsychotic Meds Tied to Kidney Problems in Elderly 3Health News:As Risperdal Lawsuits Mount, Bernstein Liebhard LLP Notes New Study Linking Atypical Antipsychotic Medications to Kidney Damage in Elderly Patients 2Health News:As Risperdal Lawsuits Mount, Bernstein Liebhard LLP Notes New Study Linking Atypical Antipsychotic Medications to Kidney Damage in Elderly Patients 3Health News:As Risperdal Lawsuits Mount, Bernstein Liebhard LLP Notes New Study Linking Atypical Antipsychotic Medications to Kidney Damage in Elderly Patients 4
(Date:8/19/2014)... MA -- MIT chemical engineers have devised a new ... are released slowly over a few weeks. When applied ... the body to rapidly form new bone that looks ... type of coated scaffold could offer a dramatic improvement ... involves transplanting bone from another part of the patient,s ...
(Date:8/19/2014)... today,s crocodiles colonised the seas during warm phases and ... Anglo-French study which establishes a link between marine crocodilian ... period of more than 140 million years. , ... Universit de Lyon, France and formerly from the University ... Nature Communications ., Today, crocodiles are ,cold-blooded, animals that ...
(Date:8/19/2014)... A team of UTSA researchers has been awarded a ... Technology and Training (NCPTT), an office of the National ... The grant will fund a one-year study of the ... of historic homes in hot, humid climates. , Radiant ... or attics that reflect heat back, thereby reducing the ...
Breaking Biology News(10 mins):Engineering new bone growth 2Engineering new bone growth 3Evolution of marine crocodilians constrained by ocean temperatures 2UTSA researcher awarded $38K+ to evaluate energy efficiency options for historic homes 2UTSA researcher awarded $38K+ to evaluate energy efficiency options for historic homes 3
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