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Polymerase in Medical News
... Innovation's (MOSTI) biotechnology conference on polymerase chain reaction (PCR). The conference will be held ... as the conference's feature event, will focus on polymerase chain reaction (PCR) and highlight the history of ... as the inventor of Thermus aquaticus (Taq) DNA polymerase for use in PCR.
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... Consensus Guideline Reached For Quantitative polymerase Chain Reaction SALT LAKE CITY, March 31 ... laboratory method called qPCR (or quantitative polymerase chain reaction) was published by a group of ... PCR (qPCR): qPCR is an extension of the polymerase chain reaction invented in 1986 by Kary Mullis, ...Anadys Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results and Highlights
... has been reported for any other non-nucleoside polymerase inhibitor. And today we are reporting that we ... ANA598 is an investigational oral non-nucleoside polymerase inhibitor that Anadys is developing for the ... has been reported for any other non-nucleoside polymerase inhibitor in a monotherapy study. A number of ...Scientists identify key roadblock to gene expression
... on top of the transcription start site, so RNA polymerase must contend with that nucleosome as soon as it ... then soon pauses at the first nucleosome the RNA polymerase encounters. "This pause is maintained until ... removal of the nucleosome and encourage the RNA polymerase to continue along its path," said key ...Urine Test for Chlamydia Shown Effective in Men
... infection is diagnosed by nucleic acid amplification tests, such as the polymerase chain reaction. But these tests are expensive, technically complex and can ... fast and accurate results in women. The new study compared the test to the polymerase chain reaction test using urine samples from more than 1,200 men, ages 16 ...New Report Just Published: World Hepatitis C Virus And Therapeutics Market Report
... and Boceprevir II-7 Telaprevir and Boceprevir - A Comparison II-8 polymerase Inhibitors (PLIs) - Adding More Teeth to HCV Pipeline II-8 Viral Polymerases II-8 polymerase Inhibitor Drugs in Pipeline by Company, Category, and Development ...Polymerase in Medical Technology
... (HCV). PSI-7851 is a second generation nucleotide polymerase inhibitor of HCV.
PSI-7851 Phase 1 ... than Pharmasset's first generation nucleoside polymerase inhibitor, RG7128 (formerly known as R7128). In ... which act as alternative substrates for the viral polymerase thus inhibiting viral replication. We currently ...
... R7227, protease inhibitor, and R7128, nucleoside polymerase inhibitor, shows significant potency in reducing ... an oral protease inhibitor and an oral nucleoside polymerase inhibitor resulted in significant HCV viral load ... with InterMune, and R7128, a nucleoside polymerase inhibitor, with Pharmasset. Further studies ...
... the Company's investigational non-nucleoside polymerase inhibitor, demonstrated potent antiviral activity ... to position ANA598 as a leading non-nucleoside polymerase inhibitor in development for the treatment of ... protease inhibitor telaprevir and the nucleoside polymerase inhibitor PSI-6130 are synergistic. These ...
... Results for Non-Nucleoside HCV polymerase Inhibitor Being Presented at AASLD SAN DIEGO, ... ANA598 as one of the leading non-nucleoside polymerase inhibitors currently in development for the ... investigational hepatitis C non- nucleoside polymerase inhibitor. ANA598 Phase I Study Results In ...
... Study of ANA598, a Non-Nucleoside NS5B polymerase Inhibitor, in Healthy Volunteers", will present ... Combinations of Antiviral Agents that Include HCV polymerase Inhibitor ANA598 have the Potential to Overcome ... inhibitor and a representative nucleoside polymerase inhibitor. About ANA598 Preclinical ...
... R7227, protease inhibitor, and R7128, nucleoside polymerase inhibitor, shows significant potency in reducing ... an oral protease inhibitor and an oral nucleoside polymerase inhibitor resulted in significant HCV viral load ... with InterMune, and R7128, a nucleoside polymerase inhibitor, with Pharmasset. Further studies ...
... the Company's investigational non-nucleoside polymerase inhibitor, demonstrated potent antiviral activity ... to position ANA598 as a leading non-nucleoside polymerase inhibitor in development for the treatment of ... protease inhibitor telaprevir and the nucleoside polymerase inhibitor PSI-6130 are synergistic. These ...
ANA598 Demonstrates Potent Antiviral Activity in an Early Clinical Study in HCV-Infected Patients
... the Company's investigational non-nucleoside polymerase inhibitor. ANA598 was very well-tolerated and ... to position ANA598 as a leading non-nucleoside polymerase inhibitor in development for the treatment of HCV ... been reported previously for all classes of HCV polymerase inhibitors, including nucleosides. This ...... Results for Non-Nucleoside HCV polymerase Inhibitor Being Presented at AASLD SAN DIEGO, ... ANA598 as one of the leading non-nucleoside polymerase inhibitors currently in development for the ... investigational hepatitis C non- nucleoside polymerase inhibitor. ANA598 Phase I Study Results In ...
... Study of ANA598, a Non-Nucleoside NS5B polymerase Inhibitor, in Healthy Volunteers", will present ... Combinations of Antiviral Agents that Include HCV polymerase Inhibitor ANA598 have the Potential to Overcome ... inhibitor and a representative nucleoside polymerase inhibitor. About ANA598 Preclinical ...
Polymerase in Medical Products
Description:... Next-generation real-time polymerase chain reaction (PCR) testing for clinical laboratories.
The COBAS TaqMan 48 Analyzer allows automated real-time amplification and detection of ...
Company:Roche Diagnostics
Description:... It is based on the principle that only primers whose sequence is completely complementary to a target sequence will be converted by the polymerase into PCR products. In contrast, non-complementary primers produce no amplification product. Using the Biotest SSP Kit Systems, reliable typing ...
Company:Biotest
Description:... It is based on the principle that only primers whose sequence is completely complementary to a target sequence will be converted by the polymerase into PCR products. In contrast, non-complementary primers produce no amplification product. Using the Biotest SSP Kit Systems, reliable typing ...
Company:Biotest
Company:Roche Molecular Systems, Inc.
Description:... The HSV Non-Typing ASR contains primers and a FAM-labeled probe that is designed to detect a 92 bp region of the HSV Type 1 and Type 2 polymerase gene. This ASR requires an instrument that can detect a FAM reporter dye like the Cepheid SmartCycler System. The Cepheid Analyte Specific Reagent* ...
Company:Cepheid
Company:Applied Biosystems
Company:Roche Diagnostics
Description:... It is based on the principle that only primers whose sequence is completely complementary to a target sequence will be converted by the polymerase into PCR products. In contrast, non-complementary primers produce no amplification product. Using the Biotest SSP Kit Systems, reliable typing ...
Company:Biotest
Description:... It is based on the principle that only primers whose sequence is completely complementary to a target sequence will be converted by the polymerase into PCR products. In contrast, non-complementary primers produce no amplification product. Using the Biotest SSP Kit Systems, reliable typing ...
Company:Biotest
TaqScreen West Nile Virus Test
Description:... Roches patented polymerase chain reaction (PCR) technology, the worlds leading nucleic acid amplification technology, is an essential component of Roches blood screening assays ...Company:Roche Molecular Systems, Inc.
Description:... The HSV Non-Typing ASR contains primers and a FAM-labeled probe that is designed to detect a 92 bp region of the HSV Type 1 and Type 2 polymerase gene. This ASR requires an instrument that can detect a FAM reporter dye like the Cepheid SmartCycler System. The Cepheid Analyte Specific Reagent* ...
Company:Cepheid
Applied Biosystems 2720 Thermal Cycler
Description:... And because its cooling vents are in the back, you can safely place it in tight spaces to save valuable bench space. Practice of the patented polymerase chain reaction (PCR) process requires a license. The Applied Biosystems 2720 Thermal Cycler is an Authorized Thermal Cycler for PCR and may be used ...Company:Applied Biosystems
Polymerase in Medical Definition
... aspirates.
Molecular pathology refers to the use of nucleic acid-based techniques, such as in-situ hybridization, reverse-transcriptase polymerase chain reaction, and nucleic acid microarrays for specialised diagnostic studies of disease in tissues and cells.
Autopsies are used to ...
... of modern scientific medical knowledge and plays a large role in evidence-based medicine . Many modern molecular tests such as flow cytometry, polymerase chain reaction (PCR), immunohistochemistry , cytogenetics , gene rearragements studies and fluorescent in situ hybridization (FISH) fall within ...
... of modern scientific medical knowledge and plays a large role in evidence-based medicine . Many modern molecular tests such as flow cytometry, polymerase chain reaction (PCR), immunohistochemistry , cytogenetics , gene rearragements studies and fluorescent in situ hybridization (FISH) fall within ...
Polymerase in Medical Dictionary
... INHIBITORS (NNRTIS): The third class of anti - HIV drugs, NNRTIs bind near reverse transcriptase's active site and subsequently inhibit its polymerase activity. Rarely, mild cases with few symptoms besides arthritis are treated with aspirin alone, although more powerful anti -inflammatory ...
... tachycardia . Not FDA approved. Bur chill SA, Lewis IJ, Abrams KR, et al.: Circulating neuroblastoma cells detected by reverse transcriptase polymerase chain reaction for tyrosine hydroxylase mRNA are an independent poor prognostic indicator in stage 4 neuroblastoma in children over ... chill ...
... Expression and DNA Repair Research Interest: Expression of mRNA in eukaryotic cells requires several dozen transcription factors in addition to RNA polymerase II. Gene therapy seems elegantly simple in its concept: supply the human body with a gene that can correct a biological malfunction that ...
... tachycardia . Not FDA approved. Bur chill SA, Lewis IJ, Abrams KR, et al.: Circulating neuroblastoma cells detected by reverse transcriptase polymerase chain reaction for tyrosine hydroxylase mRNA are an independent poor prognostic indicator in stage 4 neuroblastoma in children over ... chill ...
... Expression and DNA Repair Research Interest: Expression of mRNA in eukaryotic cells requires several dozen transcription factors in addition to RNA polymerase II. Gene therapy seems elegantly simple in its concept: supply the human body with a gene that can correct a biological malfunction that ...
Polymerase in Biological News
Molecular typesetting -- proofreading without a proofreader
... machines called RNA polymerases. "The RNA polymerase acts like an old fashioned newsprint typesetter, ... assembling letters one at a time. Similarly, RNA polymerase constructs RNA by reading the DNA and adding new ... explains Dr Cohen. There's no way for the RNA polymerase to ensure that the correct letter is always ...New piece found in the puzzle of epigenetics
... fine regulation of the cell nucleus enzyme RNA polymerase II. This transcribes the genetic information of ... basis for protein synthesis. At the same time RNA polymerase II is also responsible for the production of ... had observed that a certain region of the RNA polymerase II enzyme the carboxy-terminal domain is ...TRAPping proteins that work together inside living cells
... polymerase, a well-studied machine in cells. The polymerase is made up of many proteins that cooperate to translate DNA. One of the polymerase proteins has a tail that is known to touch the DNA and some helper proteins just before the polymerase starts translating. No one knew if this tail -- ...Properties of unusual virus revealed in research
... called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The ... phages then use the host bacterial cell's RNA polymerase to synthesize messenger RNA through a process ... It injects both its own DNA and its own RNA polymerase into bacterial cells, so it can begin the process ...Researchers study virus with unusual properties
... called N4, injects an unusual substance -- an RNA polymerase protein -- into an E. coli bacterial cell. The ... phages then use the host bacterial cell's RNA polymerase to synthesize messenger RNA through a process ... It injects both its own DNA and its own RNA polymerase into bacterial cells, so it can begin the process ...New antibiotic candidates from Braunschweig
... the natural substances block the bacterial RNA polymerase in a new manner: the natural substances append to another location within the RNA polymerase than the antibiotics previously investigated. ... of action the active substances prevent the RNA polymerase from adhering to the DNA reading of the genetic ...Polymerase in Biological Technology
... as well as representative HCV protease and polymerase inhibitors. Furthermore, ANA598 retains full ... resistance to protease inhibitors, nucleoside polymerase inhibitors and non-nucleoside polymerase inhibitors that act at binding sites distinct ...
... data on IDX184, a once-daily, oral nucleotide polymerase inhibitor prodrug currently being evaluated in a ... two clinical candidates: IDX375, a non-nucleoside polymerase inhibitor and IDX316, a protease inhibitor, both ... therapy." IDX184 Nucleotide Prodrug polymerase Inhibitor IDX184 is a liver-targeted, oral ...
... ITMN-191 (R7227) in combination with nucleoside polymerase inhibitor R7128 (Roche/Pharmasset), referred to ... (ITMN-191), a protease inhibitor, and R7128, a polymerase inhibitor, in 14 days of combination therapy. ... Pharmasset, Roche is developing R7128, an HCV RNA polymerase inhibitor, also for therapy in combination with ...
... ACTIVITY OF THE LIVER-TARGETED NUCLEOTIDE HCV polymerase INHIBITOR IDX184 CORRELATES WITH TROUGH SERUM ... IDX184, A LIVER-TARGETED NUCLEOTIDE HCV polymerase INHIBITOR: RESULTS OF A FIRST-IN-MAN SAFETY AND ... OF IDX375, A NOVEL AND POTENT NON-NUCLEOSIDE HCV polymerase INHIBITOR - Abstract #1442; Poster ...
... investigational hepatitis C non-nucleoside polymerase inhibitor. Anadys is currently enrolling ... review of ANA598, one of the few non-nucleoside polymerase inhibitors in clinical development for the ... complementary agents, ANA598, a non-nucleoside polymerase inhibitor and ANA773, an oral TLR7 agonist ...
Anadys Pharmaceuticals Reports First Quarter 2009 Financial Results and Highlights
... ANA598 is an investigational oral non-nucleoside polymerase inhibitor that Anadys is developing for the ... Activity of ANA598, a Potent Non-Nucleoside polymerase Inhibitor, In Chronic Hepatitis C Patients," at ... protease inhibitor telaprevir and the nucleoside polymerase inhibitor PSI-6130 are synergistic. These ...... data on IDX184, a once-daily, oral nucleotide polymerase inhibitor prodrug currently being evaluated in a ... two clinical candidates: IDX375, a non-nucleoside polymerase inhibitor and IDX316, a protease inhibitor, both ... therapy." IDX184 Nucleotide Prodrug polymerase Inhibitor IDX184 is a liver-targeted, oral ...
... ITMN-191 (R7227) in combination with nucleoside polymerase inhibitor R7128 (Roche/Pharmasset), referred to ... (ITMN-191), a protease inhibitor, and R7128, a polymerase inhibitor, in 14 days of combination therapy. ... Pharmasset, Roche is developing R7128, an HCV RNA polymerase inhibitor, also for therapy in combination with ...
... ACTIVITY OF THE LIVER-TARGETED NUCLEOTIDE HCV polymerase INHIBITOR IDX184 CORRELATES WITH TROUGH SERUM ... IDX184, A LIVER-TARGETED NUCLEOTIDE HCV polymerase INHIBITOR: RESULTS OF A FIRST-IN-MAN SAFETY AND ... OF IDX375, A NOVEL AND POTENT NON-NUCLEOSIDE HCV polymerase INHIBITOR - Abstract #1442; Poster ...
... investigational hepatitis C non-nucleoside polymerase inhibitor. Anadys is currently enrolling ... review of ANA598, one of the few non-nucleoside polymerase inhibitors in clinical development for the ... complementary agents, ANA598, a non-nucleoside polymerase inhibitor and ANA773, an oral TLR7 agonist ...
Polymerase in Biological Products
MasterAmp Taq DNA Polymerase Kit from EPICENTRE Biotechnologies
Description:... MasterAmp™ Taq DNA polymerase is a thermostable DNA polymerase derived from Thermus aquaticus. Having optimal ... exonuclease activity. MasterAmp Taq DNA polymerase is highly purified using a proprietary procedure ...Company:EPICENTRE Biotechnologies
Description:... AccuPrime™ Pfx DNA polymerase is ideal for high-fidelity amplification of DNA ... enzyme preparation containing recombinant DNA polymerase from Pyrococcus sp. with proofreading (3'Cut Site5' exonuclease) activity. Platinum Anti-Pfx DNA polymerase antibodies ...
Company:Invitrogen
BioTherm Taq DNA Polymerase from eEnzyme LLC
Description:... BioTherm DNA polymerase is a thermostable DNA polymerase purified from the Thermus aquaticus strain in ... isolation of thermostable enzymes processing DNA polymerase activity from thermophilic bacteria. ...Company:eEnzyme LLC
Klenow Fragment, Exonuclease Minus from Promega
Description:... DNA polymerase I Large (Klenow) Fragment, Exonuclease Minus, is a DNA-dependent DNA polymerase that lacks both the 5´→3´ and the ... activities present in intact E. coli DNA polymerase I (1,2). It is used for random primer labeling ...Company:Promega
DNA Polymerase I Large (Klenow) Fragment from Invitrogen
Description:... DNA polymerase I Large (Klenow) Fragment is a DNA polymerase that lacks the 5'Cut Site3' exodeoxyribonuclease activity of intact DNA polymerase I but it contains the 3'Cut Site5' ...Company:Invitrogen
Expand High Fidelity PLUS PCR System; Thermostable DNA polymerase mixture from Roche Applied Science
Description:... PCR Blends. This new blend combines Taq DNA polymerase with a novel proofreading protein isolated and ... mediates proofreading activity, but has no polymerase activity itself. The synergy between the ... protein and the processivity of Taq DNA polymerase is the key to Expand High FidelityPLUS Enzyme ...Company:Roche Applied Science
Polymerase in Biological Definition
... biology
2.1 Expression cloning
2.2 polymerase chain reaction (PCR)
2.3 Gel electrophoresis ... drugs against the protein can be studied.
polymerase chain reaction (PCR)
Main article: polymerase chain reaction
The ...
... polymerase Chain Reaction (PCR) is a molecular biological ... of duplication driven by an enzyme called DNA polymerase . DNA polymerase occurs naturally in living organisms, where it ...
... strand of RNA . This RNA is produced by an RNA polymerase , and is later removed and replaced with DNA by a ... DNA polymerases, such as DNA sequencing and polymerase chain reaction (PCR), require primers. The ... as a start marker for the chain reaction. In polymerase chain reaction (PCR), primers are used to ...
... . The transcription starts with initiation. RNA polymerase , an enzyme, binds to a specific region on the ... starting point, called the promoter . As the RNA polymerase binds on to the promoter, the DNA strands are ... second process is known as elongation. As the RNA polymerase travels through the strand that is opposite to ...
... the word ending in "-ase". Examples are alcohol dehydrogenase and DNA polymerase . Kinases are enzymes that transfer phosphate groups. The ... compounds Phenylalanine hydroxylase (PAH): Phospholipase polymerase : builds long chains of nucleic acid polymers from their constituents ...
... the cell to reduce production. The first step in production is for RNA polymerase to make RNA from a stretch of DNA. DNA can be thought of as a highway , with entrances and exits. The enzyme RNA polymerase is like a car . For a specific protein sequence to be made, the car ...
... polymerase Chain Reaction (PCR) is a molecular biological ... of duplication driven by an enzyme called DNA polymerase . DNA polymerase occurs naturally in living organisms, where it ...
... strand of RNA . This RNA is produced by an RNA polymerase , and is later removed and replaced with DNA by a ... DNA polymerases, such as DNA sequencing and polymerase chain reaction (PCR), require primers. The ... as a start marker for the chain reaction. In polymerase chain reaction (PCR), primers are used to ...
... . The transcription starts with initiation. RNA polymerase , an enzyme, binds to a specific region on the ... starting point, called the promoter . As the RNA polymerase binds on to the promoter, the DNA strands are ... second process is known as elongation. As the RNA polymerase travels through the strand that is opposite to ...
... the word ending in "-ase". Examples are alcohol dehydrogenase and DNA polymerase . Kinases are enzymes that transfer phosphate groups. The ... compounds Phenylalanine hydroxylase (PAH): Phospholipase polymerase : builds long chains of nucleic acid polymers from their constituents ...
... the cell to reduce production. The first step in production is for RNA polymerase to make RNA from a stretch of DNA. DNA can be thought of as a highway , with entrances and exits. The enzyme RNA polymerase is like a car . For a specific protein sequence to be made, the car ...
Polymerase in Biological Dictionary
... Taq polymerase is a thermostable DNA polymerase named after the thermophilic bacterium Thermus ... " Taq Pol", and is frequently used in polymerase chain reaction ... What is Taq ...
... T7 RNA polymerase is an RNA polymerase that catalyzes the formation of RNA in the 5'→ 3' direction. T7 polymerase is extremely promoter-specific and only ...
... Cloning Taq polymerase PCR products by T/A cloning : Taq polymerase has an ... Therefore, I recommend using a ... SLIC Sub - cloning using T4 DNA polymerase treated inserts with RecA ... We describe a ...
... of eukaryotic cells. They are transcribed by RNA polymerase II or RNA polymerase III and are involved in a variety of important ... of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining ... The U4 ...
... eukaryotic cells. They are transcribed by RNA polymerase II or RNA polymerase III and are involved in a variety of important ... of transcription factors (7SK RNA ) or RNA polymerase II (B2 RNA ), and maintaining ... Aspects ...
... factor that enables specific binding of RNA polymerase to gene promoters. Different sigma factors ... Bioinformatics Institute ... IPR013324 RNA polymerase sigma factor , regions 3 and 4 ... An ... phase (in response to the stress of ... polymerase sigma -70 factor 119 ... Alternative ...
... T7 RNA polymerase is an RNA polymerase that catalyzes the formation of RNA in the 5'→ 3' direction. T7 polymerase is extremely promoter-specific and only ...
... Cloning Taq polymerase PCR products by T/A cloning : Taq polymerase has an ... Therefore, I recommend using a ... SLIC Sub - cloning using T4 DNA polymerase treated inserts with RecA ... We describe a ...
... of eukaryotic cells. They are transcribed by RNA polymerase II or RNA polymerase III and are involved in a variety of important ... of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining ... The U4 ...
... eukaryotic cells. They are transcribed by RNA polymerase II or RNA polymerase III and are involved in a variety of important ... of transcription factors (7SK RNA ) or RNA polymerase II (B2 RNA ), and maintaining ... Aspects ...
... factor that enables specific binding of RNA polymerase to gene promoters. Different sigma factors ... Bioinformatics Institute ... IPR013324 RNA polymerase sigma factor , regions 3 and 4 ... An ... phase (in response to the stress of ... polymerase sigma -70 factor 119 ... Alternative ...
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(Date:5/23/2013)... On April 29th, 2013, UV Technologies ... of H7N9 cases and deaths. The headline read, " UV ... Subside in Northern Hemisphere as Available Daylight Increases .” In ... reported. , Quoting Kevin McGuire, president of UV Technologies, ... budding in the spring and leaves changing in the fall. ...
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(Date:5/23/2013)... The sensation of itching is hardwired into the nervous ... molecule released in the spinal cord, according to a ... molecule, known as natriuretic polypeptide b (Nppb), triggers a ... this signal is experienced as an itch. Since the ... researchers concluded that a similar process probably occurs in ...
(Date:5/23/2013)... HealthDay Reporter , , THURSDAY, May 23 (HealthDay News) ... as badly as methamphetamine or crack cocaine, a new ... ,meth mouth, or ,coke mouth, it is startling to ... less the same," said Dr. Mohamed Bassiouny, a professor ... Dentistry in Philadelphia. Methamphetamine, crack cocaine and soda ...
(Date:5/23/2013)... isolated from a person who died from H7N9 avian ... and be transmitted between ferrets. Ferrets are often used ... transmission of influenza virus between ferrets can provide clues ... in people. The research was supported, in part, by ... of the National Institutes of Health. , The researchers ...
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(Date:5/22/2013)... genetic engineering drastically reduces the time and effort ... workhorses of biotechnology, scientists are reporting. Published in ... method paves the way for more rapid development ... and other activities. , Keith Shearwin and colleagues ... the genetic material DNA into a bacterium,s genome ...
(Date:5/22/2013)... important new details on how climate change will affect ... in the Journal of Animal Ecology . This ... and informing policymakers of how species are likely to ... is a growing recognition among biologists that climate change ... that this is going to have very important consequences ...
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