Biologist finds plant polymerases IV and V are really variants of Polymerase II

... that plants have two more nuclear polymerases, pol IV and pol V. Now it is clear that these enzymes evolved from pol II over the past several hundred millions years. ...

Bridges to Excellence Launches Medical Home Program

... what we all want from our health care system." Bridges to Excellence's pol was developed in collaboration with NCQA, a leading health care quality ... there are a number of ways for physicians to be recognized under BTE's pol program: complete NCQA's new version of its Physician Practice Connections ...

Vital New Quality Data on Hospital Readmission Rates Available on Hospital Compare Website

... readmissions can be prevented through appropriate changes in care delivery." Rita Munley Gallagher, PhD, RN, senior pol icy fello w , American Nurses Association: "Registered nurses are instrumental in ensuring coordination of care for patients. Among the myriad ...

Medical College of Wisconsin recognized for AIDS intervention research

... Research headed by Jeffrey A. Kelly, Ph.D., professor of psychiatry and behavioral medicine and director of CAIR, has shown that the pol intervention when carried out in communities of gay men, inner-city women, and disadvantaged adolescents reduces levels of HIV risk behavior by ...

Global Med Technologies(R), Inc. Implements Transfusion Management System in Large Private Physician Owned Laboratory

... 350-bed hospital. MIMA has the area's largest infusion clinic for the administration of outpatient chemotherapy and other injectables and is the only pol in the country to offer a transfusion service in a nationally accredited lab. MIMA now provides laboratory services at seven of their Brevard County ...

$1.5 Million Grant to Yale for Narcolepsy-Neurotransmitter Study

... dynorphin inhibits the activity. Van den pol and first author, Ying Li, an associate research ... channels in single nerve cells. Van den pol said that these neurotransmitters had different ... simply cancel the actions of each other,” van den pol said. “But, interestingly, in the continuing ...

Little Known DNA Repair Enzyme May Be A Tumor Suppressor Gene

... enzyme, DNA polymerase zeta, also known as pol zeta, has the uncanny ability to give even ... yeast cells, and later in plants and animals, pol zeta has the remarkable ability to efficiently ... and his associates sought to determine pol zeta's key role in mice cells. To do this, they ...

POL in Medical Technology

Multiple NIH Phase 2 HIV Vaccine Trials Using Vical's Technology Produce Encouraging Results

... Both contain synthetic versions of genes encoding three HIV proteins: gag, pol and env. The DNA component also includes a gene encoding a fourth protein, nef. The gag, pol and nef genes come from HIV subtype B, the primary virus found in Europe ...

Abbott Receives Supplemental FDA Approval for its Best-in-Class in Sensitivity RealTime HIV-1 Viral Load Test

... of care in diagnostic sensitivity of 50 copies per mL. Also, unlike other assays, the Abbott RealTime HIV-1 test targets the highly conserved pol integrase region of the HIV-1 genome, giving the test its unique ability to detect and measure all known genetic variations of the virus. "Because ...

POL in Medical Products

AAFP-PT Laboratory Proficiency Testing and Quality Assurance

Description:... per year. AAFP-PT offers other education opportunities, including the pol Microscopy Atlas and pol ....
Company:American Academy of Family Physicians

LabPak POL Plus 2 Laboratory Information System

Description: ...
Company:Fletcher-Flora, Inc.

LabPak POL Plus Laboratory Information System

Description: comprehensive LIS solutions for Physician Office Laboratories are designed to fill the needs of any POL, large or small. Includes 2 additional standard instrument interfaces for a total of 3 standard instrument interfaces of your ....
Company:Fletcher-Flora, Inc.

POL in Medical Dictionary

Pol

... Encyclopedia > Disease s and Conditions > pol -Pz Disease s and Conditions Comprehensive and ... function. Mostert MC, Verkerk AJ, van de pol M, et al.: Identification of the critical region ... i Alergologii AM we WrocLawiu. Pneumonol Alergol pol (POLAND) 1994, ... Three of these-gag, ...

Myositis

... myositis , Gottron's Papule s on the Hand Dermato myositis , Heliotrope Eyelids Dermato myositis on the Legs ... Poly myositis ( pol -e-mi-o-SI-tis) is an uncommon disease that causes inflammation in your muscle s. Doctors also refer to poly myositis as a type of ...

Polymyositis

... Polymyositis ( pol -e-mi-o-SI-tis) is an uncommon disease that causes inflammation in your muscle s. Doctors also refer to polymyositis as a type of connective ...

POL in Biological News

CSHL scientists discover new way in which ubiquitin modifies transcriptional machinery

... polymerase II (abbreviated by scientists as RNA pol II). This enzyme is composed of 12 modules, each ... Asr1 has the unique ability of homing in on RNA pol II molecules that are actively turning on genes, ... that Asr1 might selectively glom on to RNA pol II molecules that are making mistakes in copying ...

New gene-silencing pathway found in plants

... eukaryotes share three essential RNA polymerases: pol I, II, and III. These polymerases are ... any of those, you die," says Pikaard. "However, pol IV and pol V -- which only plants have -- you don't need ...

Stowers Institute's Shilatifard Lab identifies new role for factor critical to transcription

... timing and location of transcript elongation by pol II is essential for development. In a paper ... causing temporary interruptions of the action of pol II in the fruit fly (Drosophila melanogaster). "Biological mechanisms such as the 'pausing' of pol II at nearby promoters have been found at many ...

Research sheds light on the mechanics of gene transcription

... to be transcribed. The researchers also tagged pol II with a fluorescent marker to track its ... by Webb -- the researchers found that over time pol II began to recycle itself within newly formed ... is, to our knowledge, the first demonstration of pol II recycling at a specific gene in vivo." Lis ...

International team compares 12 fruit fly genomes

... thought that the rate of transcription is limited by the time it takes pol II to be recruited to the promoter region, where it copies a strand of DNA ... But increasing evidence in Drosophila and other organisms indicates that pol II frequently exists in a "paused" state at the promoter: Already having ...

Genetic contributions to human brain morphology and intelligence

... the superior occipitofrontal fascicle, and the corpus callosum [Hulshoff pol et al., 2006]. For the genetic analyses, structural equation modeling and ... in areas that are under considerable genetic influence [Hulshoff pol et al., 2006]. A genetic approach to find genes involved in brain ...

Cutting-edge amfAR grants fight HIV/AIDS in the lab and on the phone

... of HIV infection Hongjie Liu, Ph.D. Virginia Commonwealth University, Richmond, VA $119,930 A pilot study of a text-messaging-enhanced pol HIV intervention program: Men involved in transactional sex with other men represent an important source of HIV transmission in China, especially ...

Massive dinosaur discovered in Antarctica sheds light on life, distribution of sauropodomorphs

... sauropods coexisted with their basal sauropodomorph cousins, including Glacialisaurus hammeri, during the Late Triassic and Early Jurassic, Smith and pol conclude in their research findings. ...

20th ECNP Congress 2007, Oct. 13-17, Vienna, Austria

... discuss the therapeutic consequences of these findings. Genetic contributions to human brain morphology and intelligence: Hilleke Hulshoff pol presents persuasive evidence how genetic factors influence the brain structure opening new insights into the reciprocal gene-environment ...

POL in Biological Technology

PolyOne Corporation Announces an Exclusive License Agreement with Battelle for Bio-Plasticizer Technology

... AVON LAKE, Ohio, Aug. 5 /PRNewswire-FirstCall/ -- PolyOne Corporation (NYSE: pol ), a premier provider of specialized polymer materials, services and solutions, announced today that it has entered into an exclusive license ...

Monsanto Company Signs Share Subscription Agreement With Devgen

... Officer of Devgen. "This strengthens Devgen's ability to develop and commercialize innovative biotech traits and seeds that meet farmers' needs." pol Bamelis, Chairman of Devgen, added: "We are pleased to strengthen our relationship with Monsanto. I would like to take the opportunity to acknowledge ...

More siRNA Vectors for RNA Interference

... control of the U6 promoter and several other RNA pol III promoters, it was found that ... have shown that different RNA pol III promoters generate small RNAs that ... to terminate transcription by RNA pol III. The insert design shown above is ...

Drive Long-Term Silencing with CMV Vectors

... performs better than most pol III promoters under long term ... clones is possible interference between the pol II and III promoters. ... it is hypothesized that when pol II and III promoters are in ...

Five Ways to Produce siRNAs

... in mammalian cells (14). RNA pol III was chosen to drive siRNA ... Plasmid Expression Vectors feature U6 and H1 pol III promoters, an ampicillin ... and colleagues (5), SECs include an RNA pol III promoter, a sequence encoding an ...

GENE SILENCING WITH PCR PRODUCTS

... to a hairpin siRNA template and an RNA pol III transcription termination site. When ... cells, the SECs are transcribed by endogenous RNA pol III to generate a small hairpin siRNA ... one or more PCRs with the included RNA pol III promoter-containing DNA ...

siRNA Design Guidelines

... also compatible with using RNA pol III to transcribe hairpin siRNAs because RNA pol III terminates transcription at 4-6 nucleotide ... as a termination signal for RNA pol III, avoid stretches of > 4 T's or A's ...

Selecting siRNA Sequences to Incorporate into the pSilencer Vectors

... to be comparable for both in vitro prepared siRNAs and RNA pol III-expressed siRNAs. This is also true for chemically synthesized siRNAs versus RNA pol III-expressed siRNAs. Therefore, it is not necessary to ...

RNA Interference and Gene Silencing: History and Overview

... expression vector developed by a different research group encodes the sense and antisense siRNA strands under control of separate pol III promoters (52 ). The siRNA strands from this vector, like the shRNAs of the other vectors, have 5 ...

siRNA Expression Vectors with Selectable Markers

... repeat is complementary to the mRNA to which the siRNA is targeted. A string of thymidines added to the 3' end serves as a pol III transcription termination site. (See Design of Vector Encoded siRNAs in sidebar). Once inside the cell, the vector ...

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POL in Biological Products

M-MLV Reverse Transcriptase from Promega

Description:... RT) is an RNA-dependent DNA polymerase that can be used in cDNA synthesis with long messenger RNA templates (>5kb). The enzyme is a product of the pol gene of M-MLV and consists of a single subunit with a molecular weight of 71kDa. The RNase H activity of M-MLV RT is weaker than the commonly used ...
Company:Promega

POL in Biological Definition

Lagging strand

... ladder now requires a new half to match it. pol III , the main DNA replication enzyme, can not ... of the leading strand . On the leading strand, pol III "reads" the DNA and adds nucleotides to it ... the DNA and adds RNA to it in short bursts. pol III lengthens the bursts, forming Okazaki ...

Okazaki fragment

... is a relatively short fragment of DNA that is created by primase and pol III along the lagging strand (see DNA replication ). They are later ... RNAse H , and the last ribonucleotide is removed by and synthesized by pol I . The nick, or a broken phosphodiester bond remaining between the ...

Retrovirus

... a nti g en) codes for core and structural proteins of the virus; pol ( pol ymerase) codes for reverse transcriptase , protease and integrase ; ...

POL in Biological Dictionary

TATA box

... The human TATA box -Binding Protein (hTBP) is a requisite protein in the assembly ... The GTFs that recognize the TATA - Box promoter for pol II (TFIID, TFIIB, TFIIF, ... TATA , box ,biological,biology dictionary,biology terminology,biology terms,biology abbreviations ... an enhancer, a ...

T7 RNA Polymerase

... RNA Polymerase is extremely sensitive to salt inhibition. ... Comparison of the T7 RNA polymerase structure with that of the homologous pol I ... The RNA polymerase (RNAP) from bacteriophage T7 has several advantages for use ... ... Structure of T7 RNA Polymerase . 3D ...

Self-splicing

... half as much ... Figure 2 Effect of exon context on RNA self - splicing and translation in vitro. ... Table 2 Self - splicing of a pol II transcript in vitro and in human cells ... Self - splicing ,biological ,biology dictionary,biology terminology,biology terms,biology ...

Ribonucleotides

... by ... Ribonucleotides are indicated by gray boxes. ... The additional flanking ribonucleotides of the D10R2 and D9R3 substrates were ... pol µ efficiently polymerizes ribonucleotides on a DNA primer. ... However, elongation of ribonucleotides or with ribonucleotides is less ...

Polyprotein

... of the mouse mammary tumor virus polyprotein precursor Pr77 ... Cell-free synthesis of a precursor polyprotein containing both gag and pol gene ... The report describes the use of transgenic plants of alfalfa as expression vector for the production of the polyprotein p1 of ...

Polygenic inheritance

... as being used to define multifactorial ... polygenic adj. Of, relating to, or determined by polygenes: polygenic inheritance . polygenically pol ' ygen ' ically ... Polygenic inheritance can explain what? ... ultifactorial inheritance is responsible for the greatest number of ...

Polymerase

... research ... Get Polymerase Chain Reaction - A Medical ... All products relating to Polymerase ... Polymerase associated factors >> pol II ... RNA polymerase II CTD repeat YSPTSPS (phospho S2) antibody - ChIP Grade ... Compare Cheap Prices for Polymerase at NexTag.com. Shop ...

Lampbrush

... recognizable lampbrush chromosomes (LBCs) ... were strikingly similar to those of the endogenous lampbrush bivalents. ... Figure 4. pol III sites in the lampbrush chromosomes of Xenopus. ... Lampbrush loops represent transcriptionally active regions of the chromosome. ... ... ...

Cloning vector

... ) ... MicroRNA-adapted Retroviral Vectors - for flexible shRNAmir cloning and expression ... Easy cloning of shRNAmir from pSM2 into pol II retroviral vectors ... A searchable gene bank of over 33,000 human full-length cDNA clones suitable and available for ... Two NotI ...