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Phosphate in Medical News

Sagent Pharmaceuticals Announces Launch of First Two Oncolytic Products: Fludarabine Phosphate for Injection, USP and Epirubicin Hydrochloride Injection

... today announced that it has launched fludarabine phosphate for injection, USP and epirubicin hydrochloride ... mL single-dose vials. About Fludarabine phosphate for Injection, USP Fludarabine phosphate for injection, USP (generic equivalent to ...

Nephrologists Indicate High Interest in AMAG Pharmaceuticals' Newly Approved Feraheme According to Latest BioTrends Report

... and "adequate reimbursement". In the phosphate binder market, Genzyme's sevelamer compounds are ... According to the survey, the need for new phosphate binders and PTH modifiers is relatively high ... ESA and IV iron therapies. Particularly in the phosphate binder market, there are a number of important ...

Innophos Holdings, Inc. Reports Second Quarter 2009 Results

... higher than the second quarter 2009 due to higher phosphate rock and phosphoric acid costs in Mexico and the ... Innophos has been in arbitration with its phosphate rock supplier, OCP, S.A., over rock prices for ... Innophos' Mexican subsidiary had breached the phosphate rock exclusivity provision in the agreement by ...

Fresh-Meat Additives May Be Dangerous for Kidney Patients

... High potassium and phosphate content is common, but labeling is not required, ... Medical School, looked at the potassium and phosphate content in "enhanced" and additive-free meats and ... per 100 grams of protein. Most foods that had phosphate and potassium additives reported them on the ...

Alzheimer's discovery could bring early diagnosis, treatment closer

... Yifan Lu, report that the addition of a single phosphate to an amino acid in a key brain protein is a ... discovered that it is the addition of a single phosphate to the Ser202 amino acid within the tau brain ... exists. "Second, the enzyme which puts this phosphate on the tau can be targeted by drugs, so therapies ...

For Dialysis Patients, More Pills = Lower Quality of Life

... pill burden reported poorer physical health. phosphate binders, medications that control the level of ... take these medications as directed. The more phosphate binders patients were prescribed, the less ... pill burden must address the number of prescribed phosphate binders, the researchers said. The study, ...

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Phosphate in Medical Technology

Shire Strives to Increase Adherence Among Chronic Kidney Disease Stage 5 Patients

... In addition to offering the highly effective phosphate binder, FOSRENOL (lanthanum carbonate), Shire has ... of patients are repeatedly non-compliant to phosphate binder therapy. Specifically, 30 percent of ... concurrent medical conditions. "Nonadherence to phosphate binder therapy is a serious problem and ...

Keryx Biopharmaceuticals, Inc. Commences Phase 1 Study of KRX-0401 (Perifosine) in Recurrent Pediatric Solid Tumors at Memorial Sloan-Kettering Cancer Center

... citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also ...

Keryx Biopharmaceuticals Announces Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also ...

Keryx Biopharmaceuticals Reports Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

... citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also ...

Keryx Biopharmaceuticals Reports Single Agent Phase 2 Data of KRX-0401 (Perifosine) Further Demonstrating KRX-0401's Activity in the Treatment of Advanced Metastatic Renal Cell Cancer

... citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also ...

Perrigo and Partner Cobrek Confirms Filing for Generic Version of Evoclin(R) and Announcement of Lawsuit by Stiefel

... Inc. has filed an Abbreviated New Drug Application (ANDA) for Clindamycin phosphate Foam 1%, a generic version of Evoclin(R) Foam 1%. The Company believes ... 2009, as measured by Wolters Kluwer Health. The ANDA for Clindamycin phosphate Foam, 1%, which was filed prior to enactment of the Q1 Program ...

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Phosphate in Medical Products

DuoVisc

Description:... sodium hyaluronate, 8.5 mg sodium chloride, 0.28 mg of disodium hydrogen phosphate dihydrate, 0.04 mg of sodium dihydrogen phosphate hydrate and q.s. water for injection U.S.P. Healon syringes are terminally ...
Company:Alcon Laboratories

Terrific Broth, Ready-Made Powder

Description:... 2 O): 7.0 0.2 Contents: Casein Peptone: 24% Yeast Extract: 47% Potassium phosphate Dibasic: 25% Potassium phosphate Monobasic: 4% Storage: Ambient To Use: Dissolve 47 gm powder per liter of ...
Company:USB Corporation

SICKLEDEX

Description:... reconstituted solubility buffer and 20l of anticoagulated whole blood or 20l of sickle cell hemoglobin control. Each test kit contains two bottles of phosphate buffer with Saponin, two buffer dispensing caps and two vials of Sodium Hydrosulfite reagent powder. Reconstituted solution has an open-vial ...
Company:Streck

Zyderm® and Zyplast® Injectable Collagen Implants

Description:... or Zyplast® collagen implants. Zyderm and Zyplast implants are composed of highly purified bovine dermal collagen that is dispersed in phosphate buffered physiological saline containing 0.3% ....
Company:INAMED Aesthetics

Immersion Oil, BTL

Description:... Immersion oil composed on polyester polyol, diphenyl cresyl phosphate and tricyclodecane ....
Company:Carl Zeiss MicroImaging, Inc.

MM-PTH RIA Test

Description:... higher than Intact or N-terminal PTH concentrations. PTH acts directly on bone and kidney and indirectly on the intestine to alter calcium and phosphate concentrations in serum and urine. PTH is helpful in discriminating between primary hyperparathyroidism, where PTH levels are elevated, and ...
Company:Diagnostic Systems Laboratories, Inc.

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Phosphate in Medical Dictionary

Calcium phosphate

... Calcium phosphate Definition: This poisoning is caused by an overdose of calcium phosphate . It can be found in some cosmetic products, as ... that provides a soft frame work, and calcium phosphate , a mineral that adds strength and hardens the ...

Hormone

... deficient in vitamin D , it is unable to properly control calcium and phosphate levels. If the blood levels of these minerals become too low, the body may produce other body hormone s to stimulate release of calcium and phosphate from ... ...

Osteoma

... rickets Causes Vitamin D helps the body properly control calcium and phosphate levels in the body. Osteoma s ( Benign Ear Cyst or Tumor ) ... (or osteoma s). Vitamin D promotes the absorption of calcium and phosphate from food and is essential in the formation of bones and teeth . A ...

Osteomalacia

... rickets Causes Vitamin D helps the body properly control calcium and phosphate levels in the body. Osteomalacia (softening of the bones) Other bone ... the kidney s. Vitamin D promotes the absorption of calcium and phosphate from food and is essential in the formation of bones and teeth . A ...

Serum phosphorus

... phosphorus Definition: The serum phosphorus test measures the amount of phosphate in the blood . Serum phosphorus may be low. Serum alkaline ... falls to 2.0 mg/dL or lower. It often results from a shift of in organic phosphate from the blood stream to various organ s and tissue s. ...

Vitamin

... defects. Vitamin D helps the body properly control calcium and phosphate levels in the body. When the body is deficient in vitamin D , it is unable to properly control calcium and phosphate levels. Vitamin B 1, or thiamine , is an essential vitamin ...

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Phosphate in Biological News

NIH stimulus funding supports Emory biomedical scientists

... for manipulating the immune system. Dietary phosphate and prostate cancer: The nutrient phosphate is an additive in products ranging from soft ... This project monitors the influence of dietary phosphate on a mouse model of prostate cancer. ...

New study reveals the protein that makes phosphate chains in yeast

... trades is polyphosphate, a long chain of phosphate molecules. Researchers at the European Molecular ... have known for a long time how bacteria make phosphate chains, but how the same process works in ... a 'tail' hanging into the cell, which removes a phosphate molecule from ATP, an important energy carrier in ...

CSHL-led team identifies key decision-point at which cells with broken DNA repair themselves or die

... decision points called gamma-H2A.X foci, has phosphate groups added to its structure at particular ... of protein --a kinase called WSTF -- attaches phosphate to critical site, a tyrosine residue, at the ... such as when the strand breaks in two the phosphate molecule placed at the decision point by WSTF has ...

Research could lead to new non-antibiotic drugs to counter hospital infections

... Lack of an adequate amount of the mineral phosphate can turn a common bacterium into a killer, ... operation or organ surgery, levels of inorganic phosphate fall. The authors of the PNAS paper, led by ... at the University of Chicago, hypothesized that phosphate depletion in the stressed intestinal tract ...

A crystal clear view of chalk formation

... nucleus. The researchers in Golm used calcium phosphate and calcium oxalate to test whether other ... also follow this crystallization pathway. Calcium phosphate is the main constituent of bones and teeth; ... with the other component - that is, carbonate, phosphate or oxalate ions. With a special electrode they ...

World fertilizer prices drop dramatically after soaring to all-time highs

... in mid-December. The price of diammonium phosphate (DAP) increased by five timesfrom $262 to $1,218 ... gasessential for nitrogen fertilizer production. phosphate prices were also driven up by a huge increase in ... of the popular DAP and other high-analysis phosphate fertilizers. The supply of ...

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Phosphate in Biological Technology

Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients

... to that reported for other currently marketed phosphate binders. There was no increase in serum calcium ... suggest that Zerenex is an effective, tolerated phosphate binder that will potentially make a significant ... significant market potential for the drug in the phosphate binder space." Mr. Bentsur continued, "We're ...

Sanofi-aventis U.S. to Acquire Oral Chronic Lymphocytic Leukemia Treatment

... U.S. commercial rights to Oforta(TM) (fludarabine phosphate film-coated tablets), an oral B-cell chronic ... and safety of orally administered fludarabine phosphate relative to intravenously administered fludarabine phosphate have not been performed. The most common adverse ...

ChartTrends(R): Bone and Mineral Metabolism in Dialysis Reveals Latest Trends in the Treatment of Calcium, Phosphorus and PTH

... laboratory values, and treatment prevalence with phosphate binders, Nutritional Vitamin D, Active Vitamin D ... patients tend to be initiated on phosphate binder monotherapy when phosphorus reaches 5.7 ... can result in lower doses of Vitamin D and phosphate binders, the converse is actually true. Patients ...

MIT virus battery could power cars, electronic devices

... (carbon nanotubes in this case), each iron phosphate nanowire can be electrically "wired" to ... percolating throughout the electrodes to the iron phosphate and transferring energy in a very short time. ... higher voltage and capacitance, such as manganese phosphate and nickel phosphate, said Belcher. Once that ...

Frost & Sullivan Recognizes ApaTech's Leadership in Orthopedic Biologics

... Silicate ions are used to selectively replace phosphate groups in the calcium phosphate crystal lattice. This new material accelerates ... graft material. The silicate substituted calcium phosphate material also displays excellent porosity at all ...

Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients

... GENZ ) today announced the U.S. launch of the phosphate binder Renvela(R) (sevelamer carbonate) for ... (sevelamer hydrochloride), the most-prescribed phosphate binder in the United States. It is a calcium-free, metal-free, non-absorbed phosphate binder and is available in the U.S. as 800mg ...

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Phosphate in Biological Products

Phosphate Sensor from Invitrogen

Description:... phosphate Sensor is a highly sensitive reagent for the ... its environment.How it worksBinding of inorganic phosphate by phosphate Sensor is rapid and tight (Kd ~ 0.1 M), resulting ...
Company:Invitrogen

Phosphate Colorimetric Assay Kit, 'EnzoLyte from AnaSpec

Description:... EnzoLyte MG phosphate Assay Kit is based on quantification of the green ... and fast, involving a single addition step for phosphate determination. Assays can be performed in tubes, ... range: detection of as little of 1.6 pmoles of phosphate and useful range between 0.02 mM and 40 mM ...
Company:AnaSpec

NDPase (GDPase, UDPase, ADPase) Assay Kit from Sigma-Aldrich

Description:... fractions based on the detection of the inorganic phosphate released from NDP by the appropriate NDPase. The ... is proportional to the amount of the inorganic phosphate released by enzymes. Biochem/physiol Actions: ... unit of NDPase releases 1 μmole of inorganic phosphate per minute at 25 C under conditions specified by ...
Company:Sigma-Aldrich

T4 Polynucleotide Kinase Exchange Reaction Buffer from Invitrogen

Description:... For use with T4 Polynucleotide Kinase for labeling of 5' ends (5' phosphate ends) of nucleic acids. In the exchange reaction T4 Polynucleotide Kinase transfers the 5' phosphate group from DNA to ADP and subsequently transfers the Gamma-phosphate of ...
Company:Invitrogen

Calcium Phosphate Transfection Kit from Invitrogen

Description:... Invitrogen's Calcium phosphate Transfection Kit provides high-quality reagents to enable the introduction of DNA into tissue culture cells via calcium phosphate ....
Company:Invitrogen

Rabbit Anti-Lipid Phosphate Phosphatase 2 (LPP2) Antibody, Unconjugated from Sigma-Aldrich

Description:... Anti-Lipid phosphate Phosphatase 2 (LPP2) fractionated antiserum buffered aqueous solution Solution in phosphate buffered saline containing 0.08% sodium azide. unique peptide derived from ...
Company:Sigma-Aldrich

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Phosphate in Biological Definition

Adenosine triphosphate

... ATP consists of adenosine and three phosphate groups. It has the empirical formula C 10 H 16 N ... cell. Also, the hydrolysis yields free inorganic phosphate and adenosine diphosphate , which can be broken down further to another phosphate ion and adenosine monophosphate . ATP can also ...

Bone

... composite material , formed mostly of calcium phosphate (in the chemical arrangement termed calcium ... containing alkaline phosphatase. This cleaves phosphate groups and acts as the foci for calcium and phosphate deposition. The vesicles then rupture and act as ...

Cellular respiration

... two molecules of 3-carbon sugar (dihydroxyacetone phosphate and glyceraldehyde-3-phosphate) which are ... 3-carbon sugars are dehydrogenated and inorganic phosphate is added to them, forming two molecules of 1,3 ... two molecules of 1,3 diphosphoglycerate lose two phosphate groups to form two molecules of ...

DNA

... , each of which consists of a sugar , a phosphate and one of four kinds of nucleobases ... bases to face the helical axis, the sugar and phosphate groups of the nucleotides run along the outside; ... requires that helicases chemically cleave the phosphate backbone of one of the strands so that it can ...

Enzyme

... polymerase . Kinases are enzymes that transfer phosphate groups. The International Union of Biochemistry ... transfer a functional group (e.g., a methyl or phosphate group) EC 3 Hydrolases : catalyze the ... that hydrolyze ATP into ADP and inorganic phosphate in order to drive some other energetically ...

Nucleotide

... nucleobase , a pentose sugar , and a phosphate or polyphosphate group . Nucleotides also play ... deoxyribose in DNA or ribose in RNA, and the phosphate chain can be a monophosphate, diphosphate, or triphosphate. A nucleotide that lacks the phosphate group is called nucleoside . Contents ...

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Phosphate in Biological Dictionary

Phosphate ion

... The phosphate ion carries a negative three formal charge ... ... In weakly-acid conditions, the dihydrogen phosphate ion (H2PO4) is most common. ... phosphate ( ) n. A salt or ester of phosphoric acid. ... ...

Phosphate group

... A phosphate , an inorganic chemical, is a salt of phosphoric ... donates the two hydrogen atoms and ionizes as a phosphate group with a ... Hypophosphatemia is an ... in which there is an abnormally low level of phosphate in the blood. The condition has many causes, but ...

Phosphatase

... A phosphatase is an enzyme that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group ... is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including ...

CAT assay

... DNA-BD Vector. pVP16 AD Vector ... PhosFree™ phosphate assay . Cat . # BK050. Product Uses Include ... recommends using the CytoPhos™ phosphate assay ( Cat . # BK054). Kit contents ... CytoPhos™ phosphate assay . Cat . # BK054. Product Uses Include ... ...

Adenosine diphosphate

... ... C10H15N5O10P2 composed of adenosine and two phosphate groups ... Sugimura T. Poly( adenosine ... diphosphate or ADP is the result ... ... phosphate is cut loose, ATP becomes ADP ( Adenosine ... chemiosmosis ... ... free inorganic phosphate and adenosine diphosphate , which can be ...

Transient transfection

... students and researchers ... 4. Transient transfection using calcium phosphate ... Transient Transfection of Procyclic form T. brucei. Notes: 1. ... protocol for transient transfection of adherent cells with calcium phosphate ... Transient . transfection often results in high ... Transient ...

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