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Phenotype in Medical News

Genome-wide association study on Parkinson's disease finds public home at NIH

... on genotype (an individuals genetic makeup), and phenotype (observable traits and characteristics). The ... such as protocols and summaries of genotype and phenotype data. The controlled-access portion of the ... to download individual-level genotype and phenotype data from which the study participants personal ...

Brain tumor treatment may increase number of cancer stem-like cells

... population" (SP) cells from mouse and human glioblastomas. "Because the SP phenotype in glioma cancer stem-like cells is mainly mediated by ABCG2, as shown by the almost complete abolition of this phenotype when ABCG2 activity is blocked, we subsequently studied the oncogenic ...

Hodgkin lymphoma -- new characteristics discovered

... a considerable part of the B cell-specific gene expression pattern. The phenotype and the characteristics of Hodgkin lymphoma cells are therefore unique. ... Hodgkin/Reed-Sternberg (HRS) cells of Hodgkin lymphoma (HL) exhibit a phenotype and characteristics that are considerably altered. Although HRS cells are ...

Chest Journal: August news briefs

... that people who are obese with asthma may carry a specific trait or phenotype that causes them to have poorer asthma control than people who are not ... function changes suggest that obese patients may have a different phenotype of asthma. This study is published in the August issue of the journal ...

Monogram Biosciences Collaborates with Gilead Sciences for Elvitegravir Phase III Studies

... conjunction with Elvitegravir during the study. Both Monogram's Integrase phenotype and genotype assays were used in Elvitegravir preclinical and Phase II ... development. PhenoSense GT(TM) is the only assay combining actual phenotype and genotype drug results in a single report. PhenoSense GT also includes ...

JCI online early table of contents: Jan. 10 2008

... genes, which make proteins that manifest the contractile phenotype of SMCs. As elimination of myocardin in SMCs isolated from the main blood ... that myocardin has a central role in maintaining the SMC contractile phenotype and that this probably explains, in part, the development of PDA in the ...

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Phenotype in Medical Technology

Inverseon's Founder and SAB Member Published in PNAS

... "Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model." The article was edited by Robert Lefkowitz, The James ... mechanism by which Beta2-adrenoceptor signaling exacerbates the asthma phenotype is not yet known, but is an active area of study. Fully understanding this ...

Cylene Pharmaceuticals Initiates Phase I Trial With CX-4945 -Breakthrough First-in Class Inhibitor of CK2

... in a wide range of cancers. CK2 drives the excessive proliferation phenotype of cancer cells through its potentiating role in key cell survival ... apoptosis and inflammation. Because CK2 contributes to the cancer phenotype via multiple cellular events, CX-4945 has been designed with the objective ...

Spherix Announces Positive Phase 2 Study Results

... in addition to minimizing the extent of atherosclerosis from carbohydrate consumption, a diet enriched in tagatose may favor a more stable plaque phenotype less likely to cause stroke or myocardial infarction. Prior Clinical Trials with Naturlose Eight healthy individuals and eight ...

Research Finding Could Revolutionize Asthma Treatment

... article in the Proceedings of the National Academy of Sciences is "Beta2-Adrenoreceptor Signaling Is Required for the Development of an Asthma phenotype in a Murine Model." Executive Director Smith invites members of the public to help fund research to find a cure and better treatments for asthma ...

Bioheart Reports Promising Results From Preclinical Study of Adipose-Derived Acute Cell Therapy

... wholly owned subsidiary affiliated with a member of Bioheart's Board of Directors. Study objectives included assessment of the distribution and phenotype of the transplanted ADSCs and complete macroscopic exam and histopathology of selected tissues in a total of six differentiated study groups of ...

CDC Misses Target With Flawed MMR/Autism Study

... colons compared to non-vaccinated age and sex matched controls? 2. In the current CDC study, only a small subgroup of children was the correct phenotype to study. From page 7, "Only 5 of 25 subjects (20%) had received MMR before the onset of GI complaints and had also had onset of GI episodes before ...
Phenotype in Medical Products

Coatest APC Resistance Kit

Description:... function in vivo and provides information on the thrombotic risk associated with inherited and acquired APC resistance. Detects the APC resistance phenotype regardless of its cause. Detects both inherited and acquired APC ....
Company:DiaPharma Group, Inc.

Variant Total GHb Program

Description:... The VARIANT™ Total GHb Program separates glycated hemoglobin from non-glycated hemoglobin regardless of phenotype and without interference from Schiff Base. Patient results are standardized to the DCCT reference to ensure accurate diabetes ....
Company:Bio-Rad Laboratories

Human Immunodeficiency Virus (HIV) Phenotype Comprehensive

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

Antigen Testing, RBC Phenotype Extended

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

Alpha-1-Antitrypsin Phenotype (includes Alpha-1-Antitrypsin)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories

HLA-A & B Phenotype

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' ...
Company:ARUP Laboratories
Phenotype in Medical Definition

Autoimmune regulator

... disease. [4] References ^ OMIM. [1] ^ Ramsey, C. et al. (2002) Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum Mol Genet 11 (4), 397-409. ^ Anderson, M.S. et al. (2002) Projection of an Immunological Self-Shadow ...
Phenotype in Medical Dictionary

Carrier

... will be entirely normal and not be a carrier . Heterozygotes for a recessive gene are called carrier s. They usually don't express the phenotype clinically, but it can frequently be identified by sensitive labor atory methods. The " venom " can be used as a carrier to transport ...
Phenotype in Biological News

Mary had a lot of lambs: Researchers identify way to accelerate sheep breeding

... said, "so there are a lot of genes controlling it." Mateescu observed the phenotype the physical expression of the gene in the researchers' flock during a ... of the protein. This means that it may be an accurate indicator for the phenotype of breeding out of season, though it's uncertain whether the gene actually ...

December 2008 highlights from Biology of Reproduction

... a paper on p. 1038, Park et al. report genetic background effects on the phenotype produced by Dax1 (Nrob1) deficiency in mice. Intriguing work from several laboratories has demonstrated that the severity of the Dax1 -deficiency phenotype is greatest on a C57BL/6J background and milder on a 129 genetic ...

NIH's Genes, Environment and Health Initiative adds 6 studies

... view study documents, such as protocols, questionnaires and summaries of phenotype data. The second is the controlled-access portion of the database, which allows approved researchers to download individual-level genotype and phenotype data from which the study participants' personal identifiers, such as ...

Cancer signatures uncovered

... One of the three described groups of cancers has an early developmental phenotype and expresses genes that are characteristic of stem cells. From a ... The third is a small group of cancers that present as a transition phenotype between these two extremes and displays both characteristics. ...

Mouse can do without man's most treasured genes

... deletion of the same gene in the mouse and in humans produces the same phenotype (an observable trait such as presence or absence of a particular disease). ... diseases, such as neurological diseases related to vacuole proteins, the phenotype is so different that it may be necessary to establish a primate model." ...

Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring

... documents, such as protocols, questionnaires and summaries of genotype and phenotype data. The second is the controlled-access portion of the database, which allows approved researchers to download individual-level genotype and phenotype data from which the study participants personal identifiers, such as ...

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Phenotype in Biological Technology

Transposagen Creates a Rat Model of the Human Immune System

... companies. "Transposagen is pleased to have characterized the world's first rat model of SCID. We now have intellectual property covering the SCID phenotype in rat and will be offering the SCID rat and other rat models of the immune system in the near future," said Dr. Eric Ostertag , CEO of ...

First-Ever Egg Donor Web Portal Becomes One of The Largest Resources for Aspiring Parents in the U.S.

... perfect donor, the comprehensive yet easy-to-use database enables intended parents to search specific donor parameters such as ethnicity, education, phenotype and more. The system then automatically generates an email that is sent directly to the registered donor agency of the individual donors. ...

Prometheus Research Signs 3-Year Contract With Simons Foundation to Expand HTSQL Informatics System for Autism Research

... Simons Foundation. "This web-based tool offers researchers unprecedented access to DNA specimens on affected families, combined with high quality phenotype data," Johnson said. The SFARI mission is to improve the diagnosis, treatment, and prevention of autism and related developmental disorders. The ...

Former GE Healthcare Director, Per Foss Appointed CEO for HUNT Biosciences

... HUNT Study, which for the past 25 years has gathered blood samples from the general population of the Nord-Trondelag region together with detailed phenotype and environmental data. Foss joins just as recruitment for the third phase, HUNT III has closed, again with an astonishing high inclusion rate of ....

Atherotech to Exhibit its VAP(R) Cholesterol Test at Internal Medicine 2009 in Philadelphia

... April 23-25, 2009, at the Pennsylvania Convention Center in Philadelphia. Used in more than 100 clinical trials, including the Heredity and phenotype Intervention (HAPI) Heart Study recently published in Science , the VAP (Vertical Auto Profile) Test is the most accurate cholesterol test available ...

Heart Disease: An Epidemic For Firefighters

... screen of more than a million genes including newly identified KIF6 (statin responsiveness gene) and 9p21 (myocardial infarction gene), advanced phenotype (blood) and imaging analyses, diet and exercise review over the year-long study. Results and explanations were presented to the groups followed by ...

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Phenotype in Biological Products

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:... that regulates both proliferation and differentiation in intestinal epithelial cells. It plays an important role in triggering cells towards the phenotype of differentiated villus enterocytes as well as in the maintenance of the phenotype. Clone CDX2-88 reacts with a conserved epitope of the 40kD CDX2 ...
Company:BioGenex

BL21 Competent Cell Set* from Novagen

Description:... for proper folding and activity, and alleviating codon usage incompatibilities. Every strain of Novagen’s competent cells is verified for phenotype and purity, and transformation efficiency is guaranteed. The standard aliquot is 0.2 ml, which provides enough cells for 10 transformations; pack ...
Company:Novagen
Phenotype in Biological Definition

Gene

... ("complex" or "multifactoral") traits. The term phenotype refers to the characteristics that result from ... or antagonistically to generate a trait or phenotype . The ways that gene copies interact are ... the relationship between DNA strand and a phenotype trait is not direct. The same DNA strand in 2 ...

Phenotype

... The phenotype of an individual organism is either its total ... or eye color, that varies between individuals. phenotype is determined to some extent by genotype , or by ... biology . The interaction between genotype and phenotype has often been described using a simple ...

Population genetics

... map a population of genotypes ( G 1 ) to a phenotype space ( P 1 ), where selection takes place, ... in plant and animal breeding , operating in phenotype space. The missing part is the mapping between the genotype and phenotype space. This leads to a "sleight of hand" (as ...

Blood type

... 4 Rare phenotypes 4.1 Bombay phenotype 5 Compatibility 6 Frequency 7 ... related to Rh. Rare phenotypes Bombay phenotype The rare individuals with Bombay phenotype do not express substance H on their red blood ...

Epigenetics

... seemed to postulate a one-to-one correspondence between genotype and phenotype , could not explain cell differentiation. They developed a theory that ... the causal interactions between genes and their products which bring the phenotype into being”. However the term goes back at least to 1896 (see ...

Genetics

... although, in many instances, do not completely determine, the final phenotype of the organism. The phrase to code for is often used to mean a gene ... genetics, aims to predict the response to selection given data on the phenotype and relationships of individuals. A more recent development of ...

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Phenotype in Biological Dictionary

Transformed phenotype

... We have investigated whether the transformed phenotype is due to Rho activation. ... Other effects of Ras transformation must contribute to the phenotype . ... ... alter the phenotype of 3T3 cells transformed by an ... autocrine ...

Phenotype

... A phenotype is any observable characteristic or trait of ... expression of an organism's genes ... phenotype ( ) n. The observable physical or biochemical ... by both genetic makeup and environmental phenotype what an organism looks like as a consequence of ...

Genotype

... or ... the relation between genotype and phenotype is illustrated, ... Genotype and phenotype An individual's genotype is the composition, in ... belongs as ... 2. Partial Genotype and Partial phenotype ... 3. Mapping Genotype ...

True-breeding

... true " means that two organisms with a particular, heritable phenotype produce only offspring with ... (Redirected from Breeding ... alternate alleles are identical, ... The recessive trait's phenotype only appears in true - breeding (homozygous) individuals ... That is ...

Reciprocal cross

... of Reciprocal at Dictionary.com a free online dictionary ... or phenotype as the complementary female or male parent in the other cross . ... ... reciprocal adj. Concerning each of two or more persons or things. ... or phenotype as the complementary female or male parent in the other cross . ... ...

Recessive gene

... the effects of the different versions of a particular gene on the phenotype of an organism. Many animals and plants have two copies of each gene ... of ... The only way the recessive version of a gene shows as your phenotype (in this ... In genetics, the term " recessive gene " refers to an ...

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Other Contents
(Date:8/31/2014)... (PRWEB) August 31, 2014 Priya ... NutriGold , expressed concern over misinformation about weight-loss ... conflicting and, quite often, misleading information being propagated ... TV personalities are weighing in on the ... about vitamins, supplements, and especially weight-loss products and ...
(Date:8/31/2014)... Healthy Grid announced the impending release ... lollipops will use herbs to fight the bacteria that cause ... fight bacteria while stimulating saliva production. , “We're very excited ... of Healthy Grid. “Even though personal dental care is on ... little more prevention. Cavities are painful and expensive but these ...
(Date:8/31/2014)... Brook Forest Voices , audiobook producer and ... Short Stories of Wisdom and Kindness from Around the ... Jackson author, speaker, humanitarian and cultural economist. , In ... vast volume of meticulously handwritten notes taken while traveling ... behalf of Project C.U.R.E . Founded in 1987 ...
(Date:8/31/2014)... denervation seems to be more successful at reducing blood ... accessory renal arteries, according to research presented at ESC ... Dr Schmiedel said: "More than one billion people worldwide ... pressure (BP) greater than 140/90 mmHg. Up to 15% ... unable to reduce BP below 140/90 mmHg despite adhering ...
(Date:8/30/2014)... Local anaesthetic is as safe and effective for transcatheter ... results of the FRANCE 2 registry presented at ESC ... Dr Chopard said: "Numerous studies have shown that TAVI ... symptomatic aortic stenosis who are at very high risk ... number of TAVI procedures in France and around the ...
Breaking Medicine News(10 mins):Health News:New Reasons to Verify Label Claims on Weight-loss Products Before Buying 2Health News:New Reasons to Verify Label Claims on Weight-loss Products Before Buying 3Health News:Healthy Grid: Fight Cavities With Sweet Treats 2Health News:Healthy Grid: Fight Cavities With Sweet Treats 3Health News:Brook Forest Voices Announces End of Summer Release! Dr. James Jackson’s, “Simplicity & Sophistication” Audiobook 2Health News:Renal denervation more successful when it includes accessory arteries 2Health News:Local anesthetic for TAVI as safe and effective as general anesthetic 2
(Date:8/28/2014)... significant health risk to people with asthma according to a ... Clinical Immunology . , By critically reviewing the findings from ... that the presence of several types of mould can lead ... the likelihood of developing the condition. , The research has ... Medical School and is the first time all of the ...
(Date:8/28/2014)... California, and Alaska totaled 515 million board feet in ... of more than 10 percent compared to the first ... Research Station reported today. During this same period, West ... million board feet. , The total value of these ... $390 million in the same quarter, while the total ...
(Date:8/28/2014)... Ludwig-Maximilians-Universitaet (LMU) in Munich have assigned a number ... predatory arthropods. These animals lived in shallow marine ... forms found in Jurassic strata. , Before ... marine habitat and were fossilized some 435 million ... of the Silurian seas although they were ...
Breaking Biology News(10 mins):Indoor mold poses health risk to asthma sufferers 2West coast log exports up, lumber exports down in second quarter of 2014 2Paleontology: Oldest representative of a weird arthropod group 2
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