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Phage in Medical News

New viruses to treat bacterial diseases -- 'My enemies' enemy is my friend'

... a virus that only attacks bacteria, called a phage and some phages only attack specific types of ... of the viruses by DNA analysis to utilise phage with different profiles. Using phages rather ... are fighting the disease-causing bacteria phage based treatment has been largely ignored until ...

New Research Shows MicroPhage Test Accurately and Rapidly Detects Serious Bacterial Infections

... is challenged with an antibiotic. Because phages depend on host bacteria for growth, any compound that kills or inhibits the microbe will stop phage growth. Only resistant strains allow multiplication of phages and yield a positive signal on the detector strip. Further information about the ...

XOMA to Present at the Rodman and Renshaw Annual Global Investment Conference on November 11

... (certolizumab pegol) for Crohn's disease. The Company has a premier antibody discovery and development platform that incorporates leading antibody phage display libraries and XOMA's proprietary Human Engineering(tm) and bacterial cell expression technologies. Bacterial cell expression is a key ...

XOMA to Announce Third Quarter 2008 Financial Results and Host Conference Call on November 10

... (certolizumab pegol) for Crohn's disease. The Company has a premier antibody discovery and development platform that incorporates leading antibody phage display libraries and XOMA's proprietary Human Engineering(tm) and bacterial cell expression technologies. Bacterial cell expression is a key ...

Sanofi-aventis: Encouraging First-Quarter 2008 Results Further Positive Phase III Results for Eplivanserin

... in sleep quality Filing for approval scheduled for the second half of 2008 * Agreement with Dyax on a human monoclonal antibody and on phage Display technology Confirmation of 2008 Guidance The first-quarter results support 2008 full-year guidance at constant EURO/dollar parity ...

Experts to Develop New Weapons Against Food Poisoning

... company like GangaGen that is at the forefront of phage technology development. Our team's ... building a business relationship to commercialise phage technology which has been developed at the University to complement the existing phage expertise of GangaGen. This is part of the ...

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Phage in Medical Technology

Pieris Reports Development Progress for Anticalin(R) PRS-050, a Next Generation VEGF Antagonist

... Management Angiogenesis. Kristian Jensen joins Pieris from Merck Serono, where he spent almost three years establishing and managing its phage display antibody facility in Geneva, Switzerland. Prior to Merck Serono, he obtained his research management experience during four years as Group ...

MicroPhage Successfully Completes Beta Trial for Rapid MRSA Test

... is challenged with an antibiotic. Because phages depend on host bacteria for growth, any compound that kills or inhibits the microbe will stop phage growth. Only resistant strains allow multiplication of phages and yield a positive signal on the detector strip. Further information about the ...

Athera Biotechnologies and Dyax Announce a Collaboration to Discover and Develop Antibodies for Cardiovascular Inflammation

... Athera has identified an exciting potential opportunity for therapeutic antibody treatment of cardiovascular inflammation." "The strength of Dyax's phage display technology, screening capabilities and expertise in drug discovery make them an excellent partner to advance our cardiovascular research ...

Preclinical Data on Cytogen's Technology to be Reported at the AACR Annual Meeting

... 8:00 AM -12:00 PM Abstract #645: Studies with long random phage libraries: Epitope-specific peptides recapitulate antibody ... nanoparticles coated with active-transport peptides derived from phage libraries. The abstracts are available and can be viewed on-line at no ...

Viral Enzyme Recruited in Fight Against Ear Infection

... phages to break out of bacteria they infect by using a special enzyme to destroy the cell walls. The success of the new treatment, which uses a phage enzyme called lysin to kill S. pneumonia, suggests that the strategy could significantly reduce the incidence of acute otitis media in the United ...

DX-88 for Hereditary Angioedema Meets Primary and Secondary Endpoints in Phase 3 Trial (EDEMA3)

... including CABG and heart valve replacement or repair procedures. Dyax identified DX-88 and other compounds in its pipeline using its patented phage display technology, which rapidly selects compounds that bind with high affinity and specificity to therapeutic targets. Dyax leverages this ...
Phage in Medical Definition

Medical procedure

... care Hyperbaric oxygen therapy Oxygen therapy Gene therapy Enzyme replacement therapy Intravenous therapy Kinesiotherapy phage therapy Serotherapy Respiratory therapy Vision therapy Electrotherapy Transcutaneous electrical nerve stimulation (TENS) Laser ...
Phage in Medical Dictionary

Deficiency

... ... phagedenic; phagedenical; phagedenic ulcer ; phagedenous; phage integrase family; phagemid; phage typing; phago-; phagocyte ; phagocyte bactericidal dysfunction; ...

Phagocyte

... tropica; phagedenic; phagedenical; phagedenic ulcer ; phagedenous; phage integrase family; phagemid; phage typing; phago-; phagocyte ; ... Ceplene ( histamine dihydro chloride ...

Monocyte

... white blood cells (see blood ; immunity ). E. chaffeensis invades monocyte s; granulocytic Ehrlichia invades granulocyte s. phagemid; phage typing; phago-; phagocyte ; phagocyte bactericidal dysfunction; phagocyte dysfunction; phagocytic; phagocytic dysfunction disorders immuno ...
Phage in Biological News

NYU scientists discover dangerous new method for bacterial toxin transfer

... microbes. When they modeled that phage therapy in the lab, however, the NYU researchers ... in raw milk. The unwitting selection of a phage with similar properties for mastitis therapy ... a protein protruding from the cell where the phage can dock. Bacteriophages also generally kill ...

Properties of unusual virus revealed in research

... which ultimately results in the creation of new phage proteins. These new proteins are used to construct new phages inside the bacterial cell. But the phage that we are studying is different. It injects ... RNA polymerase." The team says that the N4 phage that they are studying is the ...

Researchers study virus with unusual properties

... which ultimately results in the creation of new phage proteins. These new proteins are used to construct new phages inside the bacterial cell. But the phage that we are studying is different. It injects ... RNA polymerase." The team says that the N4 phage that they are studying is the ...

Tips from the Journals of the American Society for Microbiology

... phage Therapy May Control Staph Infections in Humans ... higher mortality rate. A bacteriophage, or phage for short, is a virus that infects bacteria. In ... These results suggest a potential use of the phage for the control of both local and systemic human ...

Biologists surprised to find parochial bacterial viruses

... biologist Forest Rohwer, who has prepared the world's largest database of phage DNA. In the first step of the tests, researchers crushed small bits of the ... Finally, all three of these metagenomes were compared with Rohwer's phage database and with several large gene-sequence databases, like GenBank. ...

Hidden interactions between predators and prey: evolution causes cryptic dynamics in ecology

... species in a laboratory microcosm, the bacterium Escherichia coli and the phage virus T4. Despite wide swings in phage abundance, they maintained a constant bacterial population by including ...

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Phage in Biological Technology

Tips from the Journals of the American Society for Microbiology

... phage Therapy May Control Staph Infections in Humans ... higher mortality rate. A bacteriophage, or phage for short, is a virus that infects bacteria. In ... These results suggest a potential use of the phage for the control of both local and systemic human ...

Calvert Research and Auburn University Announce Joint Venture

... pharmaceutical nanocarriers, such as liposomes, with breast tumor-specific phage proteins may significantly enhance their anti-cancer activity. "This ... Petrenko said. "Their experts first recognized that the merging of phage nanobiotechnology developed at Auburn with genomics can contribute ...

Peregrine Pharmaceuticals Licenses Anti-VEGF Antibodies to Affitech

... clinical data." Commenting on the licensing agreement, Dr. Achim Kaufhold, chief executive officer of Affitech, said, "Using advanced phage display technologies, Affitech successfully identified fully human, potent and selective anti-VEGF antibodies as part of a previous research and ...

TechConnect World Publishes Conference Agenda Featuring More than 2,700 Presentations Addressing Nano, Bio and Clean Technologies

... Medical & Biotech Track - focusing on cancer research; drug delivery; nano medicine; Bio-nano materials; biosensors & diagnostics; phage engineering, and other topics. Business & Strategy Track - addressing novel products, investments & business; education & ...

Frost & Sullivan Recognizes ESBATech's Innovation in Developing Antibody Fragments for Biologic Therapeutics

... independent screening platform, Immuna(R), for selecting and optimizing highly-stable, single-chain antibody fragments (scFv) without any phage display." ESBATech's successful screening and characterization of all 1.5 million naturally occurring antibody fragment frameworks resulted in ...

Using living cells as nanotechnology factories

... methods to copy branched DNA structures, and there has also been significant work in using long-stranded DNA sequences replicated from cells or phage viruses to scaffold short helper DNA sequences to form 2-D or 3-D objects," said Yan, who is also a professor in the Department of Chemistry and ...

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Phage in Biological Products

T7 Phage Capture Plate from Novagen

Description:... The T7 phage Capture Plate is a 96-well ELISA-compatible plate ... This 8-well strip plate has a capacity of 10 9 phage per well and low non-specific binding. phage binding is linear over two orders of magnitude. ...
Company:Novagen

Ph.D. Peptide Display Cloning System from New England Biolabs

Description:... of 5 displayed peptides per virion. The use of a phage vector, rather than a phagemid, simplifies the ... since neither antibiotic selection nor helper phage superinfection are required. Since displayed ... effect on the infectivity function of pIII in phage vectors, this vector is suitable only for the ...
Company:New England Biolabs

Rabbit Anti-M13 Genomic DNA Polyclonal Antibody, Unconjugated from Aviva Systems Biology

Description:... was derived from rabbit immunized with highly purified M13 bacterial phage particles.Recombinant protein domains such as antibody fragments can be fused to M13 coat protein pIII and displayed on phage using phagemid-based systems (1), rather than the phage-based system ...
Company:Aviva Systems Biology

Kilo Sequencing Deletion Kit from Takara Mirus Bio

Description:... The Deletion Kit for Kilo-Sequencing is designed to aid sequence analysis of long DNA fragments cloned into the multiple cloning sites (MCS) of M13 phage vectors (mp18/19) or pUC-related plasmid or phagemid vectors (pUC18/19). The kit is used to create nested unidirectional deletions in the target DNA, ...
Company:Takara Mirus Bio

pCITE-2a(+) DNA from Novagen

Description:... I and Xcm I sites. Subtract 5 bp from all sites beyond Msc I at 522. The f1 origin in pCITE-2a-c(+) vectors is oriented so that infection with helper phage wil produce virions containing single stranded DNA that is complementary to the strand shown on the vector map. Therefore, single stranded sequencing ...
Company:Novagen

pWEB::TNC Deletion Cosmid Transposition Kit from EPICENTRE Biotechnologies

Description:... and dephosphorylated pWEB::TNC Cosmid Vector, packaged using ultra-high efficiency MaxPlax™ Lambda Packaging Extracts (>10 9 pfu/ m g for phage lambda), also in the kit, and plated on the supplied EPBOS™ plating ....
Company:EPICENTRE Biotechnologies

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Phage in Biological Definition

Antibiotic resistance

... 3.1 Prevention 3.2 Vaccines 3.3 phage therapy 4 See also 5 External links ... of more effective vaccines is under way. phage therapy phage therapy is a more recent alternative that can ...

Hershey-Chase experiment

... of phages and, ultimately, of all organisms. A phage is a small virus that infects bacteria . It ... coat that encloses the genetic material. When a phage infects a bacterium, it inserts its genetic ... experiments, bacteria were separated from the phage coats by blending followed by centrifugation . ...

Lambda phage

... Enterobacteria phage λ ( lambda phage ) is a temperate phage that lives in E. coli . Once ...

Antibiotic resistance

... 3.1 Prevention 3.2 Vaccines 3.3 phage therapy 4 See also 5 External links ... of more effective vaccines is under way. phage therapy phage therapy is a more recent alternative that can ...

Phage

... A phage (also called bacteriophage ) (in Greek ... Mark Mller says: Bacteria don't die, they just phage away. ) Some phages (so-called temperate phages ... in the lysis of the host cell. An example is phage λ of E. coli . Sometimes, prophages even ...

Prophage

... A prophage is a temperate phage in its integrated status. Its genome can be integrated into the ... as an extrachromosomal plasmid . When stress in the host is detected, the phage enters its reproductive cycle. ...

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Phage in Biological Dictionary

Prophage

... A prophage is a phage genome inserted as part of the linear ... the DNA chromosome of a bacterium. A temperate phage integrated into the host chromosome or ... episome. A bacterial ... A prophage is the phage DNA in its dormant state, and is either ...

Phagemid

... developed as a hybrid of the filamentous phage M13 and plasmids to produce a vector that can ... developed as a hybrid of the filamentous phage M13 and plasmids to produce a vector that ... phagemid pG8H6 (10) was used to construct the phage display library. ... After incubation overnight, ...

Phage

... The term is commonly used in its shortened form, phage . phage therapy is the therapeutic use of ... this method of therapy ... Welcome to phage Biotechnology Corp., A manufacturer of protein ...

Lambda phage

... Lambda phage is a virus particle consisting of a head, containing double ... The repressor found in the phage lambda is a notable example of the level of ... lambda phage DNA is either linear, circular, or concatenated. ...

Genomic library

... 23. Medicago ... The first Mt genomic libraries were constructed in phage lambda derivatives in the 1990s. ... [While gel is running, you ... of host bacteria, each of ... ... size (use 20 kb for a lambda phage genomic library ), and the size of the genome ... A genomic DNA ...

Cosmid

... spliced with plasmid DNA for cloning large ... · plasmid · lambda phage · cosmid · P1 phage · fosmid · BAC ... Information about cosmid in the free online ...

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