Anisomycin from Sigma-Aldrich
Description:... Antibiotic isolated fromStreptomyces griseolusthat inhibits protein synthesis. Acts by inhibiting peptidyl
transferase activity in eukaryote ribosomes. Reported to induce apoptosis in a variety of cells including promyelocytic leukemia cells, Jurkat cells, ...
... The peptidyl
transferase is an aminoacyltransferase (EC ... protein biosynthesis. Aspects of the topic peptidyl
- transferase are discussed in the following ... Synthesis of proteins ) 6. The enzyme peptidyl
transferase , which is part of the larger of the ...
Ribosome binding site
... binding site (RBS) is a sequence on mRNA that is bound by the ribosome when initiating protein translation. The P site is where the peptidyl
tRNA is formed in the ribosome . ... This binding is facilitated by elongation factor-Tu (EF-Tu), a small GTPase. ... Definition and other ...